Methyl 4-hydroxyquinoline-3-carboxylate
AlkaPlorer ID: AK005033
Synonym: None
IUPAC Name: methyl 4-oxo-1H-quinoline-3-carboxylate
Structure
SMILES: COC(=O)C1=CNC2=CC=CC=C2C1=O
InChI: InChI=1S/C11H9NO3/c1-15-11(14)8-6-12-9-5-3-2-4-7(9)10(8)13/h2-6H,1H3,(H,12,13)
InChIKey: VFKCZUXTGSMROI-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Penicillium sp. | Penicillium | Aspergillaceae | Eurotiales | Eurotiomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 203.197
TPSA？: 59.160000000000004
MolLogP？: 1.3146999999999998
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Mus musculus | J774 | EC50 | 20000.0 | nM | 10.1021/acs.jmedchem.6b00759 |
| Plasmodium berghei | Plasmodium berghei | EC50 | 3.65 | nM | 10.1021/acs.jmedchem.6b00759 |
| Plasmodium falciparum | Plasmodium falciparum | EC50 | 200.0 | nM | 10.1021/acs.jmedchem.6b00759 |
| Plasmodium falciparum | Plasmodium falciparum | EC50 | 6590.0 | nM | 10.1021/acs.jmedchem.6b00759 |
| Plasmodium falciparum | Plasmodium falciparum | Ratio EC50 | 33.0 | None | 10.1021/acs.jmedchem.6b00759 |
| None | Unchecked | Ratio EC50 | 54.8 | None | 10.1021/acs.jmedchem.6b00759 |
| None | Unchecked | Ratio EC50 | 1810.0 | None | 10.1021/acs.jmedchem.6b00759 |