3-hydroxypyridine
AlkaPlorer ID: AK005118
Synonym: None
IUPAC Name: pyridin-3-ol
Structure
SMILES: OC1=CC=CN=C1
InChI: InChI=1S/C5H5NO/c7-5-2-1-3-6-4-5/h1-4,7H
InChIKey: GRFNBEZIAWKNCO-UHFFFAOYSA-N
Reference
Thermal degradation products derived from the smoke of Salvia divinorum leaves
PubChem CID: 7971
CAS: 109-00-2
LOTUS: LTS0067108
SuperNatural Ⅲ: SN0113249
COCONUT: CNP0191812
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Paeonia suffruticosa | Paeonia | Paeoniaceae | Saxifragales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 95.101
TPSA？: 33.120000000000005
MolLogP？: 0.7871999999999999
Number of H-Donors: 1
Number of H-Acceptors: 2
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Electrophorus electricus | Acetylcholinesterase | Activity | nan | None | 10.1021/acs.jmedchem.7b01620 |
| Homo sapiens | Cytochrome P450 3A4 | IC50 | 767361.49 | nM | 10.1016/j.ejmech.2008.12.004 |
| Homo sapiens | MIA PaCa-2 | IC50 | 56480.0 | nM | 10.1021/jm070396q |
| Homo sapiens | MIA PaCa-2 | IC50 | 73100.0 | nM | 10.1021/jm070396q |
| Homo sapiens | MRC5 | IC50 | 500000.0 | nM | 10.1016/j.ejmech.2017.12.070 |
| Homo sapiens | PI3-kinase p110-alpha/p85-alpha | Inhibition | 25.0 | % | 10.1016/j.bmc.2017.01.012 |
| Homo sapiens | PI3-kinase p110-alpha subunit | Inhibition | 25.0 | % | 10.1016/j.bmc.2017.01.012 |
| Homo sapiens | T98G | IC50 | 500000.0 | nM | 10.1016/j.ejmech.2017.12.070 |
| Homo sapiens | U-118-MG | IC50 | 500000.0 | nM | 10.1016/j.ejmech.2017.12.070 |
| Homo sapiens | U-87 MG | IC50 | 500000.0 | nM | 10.1016/j.ejmech.2017.12.070 |
| Staphylococcus aureus | Quinolone resistance protein norA | Activity | 128.0 | ug ml-1 | 10.1021/jm401808n |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 64.0 | ug.mL-1 | 10.1021/jm401808n |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 128.0 | ug.mL-1 | 10.1021/jm401808n |