(19R)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
AlkaPlorer ID: AK005222
Synonym: '10-Hydroxycamptothecin', 'MLS002695962', 'SMR001562120'
IUPAC Name: (19R)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Structure
SMILES: CC[C@]1(O)C(=O)OCC2=C1C=C1C3=NC4=CC=C(O)C=C4C=C3CN1C2=O
InChI: InChI=1S/C20H16N2O5/c1-2-20(26)14-7-16-17-11(5-10-6-12(23)3-4-15(10)21-17)8-22(16)18(24)13(14)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m1/s1
InChIKey: HAWSQZCWOQZXHI-HXUWFJFHSA-N
Reference
A camptothecin derivative from nothapodytes foetida
PubChem CID: 14440697
LOTUS: LTS0249424
SuperNatural Ⅲ: SN0120599-02
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Camptotheca acuminata | Camptotheca | Nyssaceae | Cornales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 364.35700000000014
TPSA？: 101.65
MolLogP？: 1.7851999999999992
Number of H-Donors: 2
Number of H-Acceptors: 7
RingCount: 5
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|