(+-)-Norreticuline
AlkaPlorer ID: AK005448
Synonym: None
IUPAC Name: 1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol
Structure
SMILES: COC1=C(C=C(C=C1)CC2C3=CC(=C(C=C3CCN2)OC)O)O
InChI: InChI=1S/C18H21NO4/c1-22-17-4-3-11(8-15(17)20)7-14-13-10-16(21)18(23-2)9-12(13)5-6-19-14/h3-4,8-10,14,19-21H,5-7H2,1-2H3
InChIKey: FVEMXQCEJGGXJB-UHFFFAOYSA-N
Reference
Identification of Pavinane Alkaloids in the Genera <b>Argemone</b> and <b>Eschscholzia</b> by GC-MS
PubChem CID: 443766
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Stephania kwangsiensis | Stephania | Menispermaceae | Ranunculales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Erythrina corallodendron | Erythrina | Fabaceae | Fabales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 315.369
TPSA？: 70.95
MolLogP？: 2.544500000000001
Number of H-Donors: 3
Number of H-Acceptors: 5
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Rattus norvegicus | Adrenergic receptor alpha | Ki | 7500.0 | nM | 10.1021/jm00180a013 |
| Rattus norvegicus | Adrenergic receptor beta | Ki | 4000.0 | nM | 10.1021/jm00180a013 |
| Rattus norvegicus | Dopamine receptor | Ki | 3800.0 | nM | 10.1021/jm00180a013 |