Molecule

Noracronycine

AlkaPlorer ID: AK005504

Synonym: None

IUPAC Name: 6-hydroxy-3,3,12-trimethylpyrano[2,3-c]acridin-7-one

Structure

SMILES: CN1C2=CC=CC=C2C(=O)C2=C(O)C=C3OC(C)(C)C=CC3=C21

InChI: InChI=1S/C19H17NO3/c1-19(2)9-8-12-15(23-19)10-14(21)16-17(12)20(3)13-7-5-4-6-11(13)18(16)22/h4-10,21H,1-3H3

InChIKey: CBXBWBNEFPNSDO-UHFFFAOYSA-N

Reference

Acridone alkaloids. Part 9. Chemical constituents of Glycosmis citrifolia(Willd.) Lindl. Structures of novel linear pyranoacridones, furoacridones, and other new acridone alkaloids

PubChem CID: 5320199

CAS: 13161-79-0

LOTUS: LTS0057116

COCONUT: CNP0385863

data_source: manually

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Boenninghausenia albiflora	Boenninghausenia	Rutaceae	Sapindales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota

Properties Information

Molecule Weight: 307.349

TPSA？: 51.46000000000001

MolLogP？: 3.581500000000003

Number of H-Donors: 1

Number of H-Acceptors: 4

RingCount: 4

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Homo sapiens	A498	GI50	13458.6	nM	None
Homo sapiens	A549	GI50	25003.45	nM	None
Homo sapiens	A549	IC50	40000.0	nM	10.1021/np980504z
Homo sapiens	CAKI-1	GI50	3047.89	nM	None
Homo sapiens	CCRF-CEM	GI50	25003.45	nM	None
Homo sapiens	CCRF-HSB-2	IC50	40000.0	nM	10.1021/np980504z
Homo sapiens	COLO 205	GI50	25003.45	nM	None
Homo sapiens	DLD-1	GI50	19364.22	nM	None
Homo sapiens	DMS-114	GI50	25003.45	nM	None
Homo sapiens	DMS-273	GI50	25003.45	nM	None
Homo sapiens	EKVX	GI50	21086.28	nM	None
Homo sapiens	HCC 2998	GI50	25003.45	nM	None
Homo sapiens	HCT-116	GI50	25003.45	nM	None
Homo sapiens	HCT-15	GI50	25003.45	nM	None
Homo sapiens	HL-60	GI50	11091.75	nM	None
Homo sapiens	HOP-18	GI50	13708.82	nM	None
Homo sapiens	HOP-62	GI50	25003.45	nM	None
Homo sapiens	HOP-92	GI50	25003.45	nM	None
Homo sapiens	HT-29	GI50	25003.45	nM	None
Homo sapiens	IGROV-1	GI50	25003.45	nM	None
Homo sapiens	K562	GI50	25003.45	nM	None
Homo sapiens	KB	Activity	nan	None	10.1021/np50027a016
Homo sapiens	KM12	GI50	25003.45	nM	None
Homo sapiens	KM-20L2	GI50	10162.49	nM	None
Homo sapiens	LOX IMVI	GI50	25003.45	nM	None
Homo sapiens	M19-MEL	GI50	25003.45	nM	None
Homo sapiens	Malme-3M	GI50	25003.45	nM	None
Homo sapiens	MCF7	GI50	25003.45	nM	None
Homo sapiens	MOLT-4	GI50	6280.58	nM	None
Homo sapiens	NCI/ADR-RES	GI50	25003.45	nM	None
Homo sapiens	NCI-H226	GI50	25003.45	nM	None
Homo sapiens	NCI-H23	GI50	25003.45	nM	None
Homo sapiens	NCI-H322M	GI50	25003.45	nM	None
Homo sapiens	NCI-H460	GI50	25003.45	nM	None
Homo sapiens	NCI-H522	GI50	25003.45	nM	None
Homo sapiens	OVCAR-3	GI50	25003.45	nM	None
Homo sapiens	OVCAR-4	GI50	25003.45	nM	None
Homo sapiens	OVCAR-5	GI50	25003.45	nM	None
Homo sapiens	OVCAR-8	GI50	2500.35	nM	None
Homo sapiens	RPMI-8226	GI50	25003.45	nM	None
Homo sapiens	RXF 393	GI50	10162.49	nM	None
Homo sapiens	SF-268	GI50	25003.45	nM	None
Homo sapiens	SF-295	GI50	25003.45	nM	None
Homo sapiens	SF-539	GI50	25003.45	nM	None
Homo sapiens	SK-MEL-2	GI50	25003.45	nM	None
Homo sapiens	SK-MEL-28	GI50	25003.45	nM	None
Homo sapiens	SK-MEL-5	GI50	25003.45	nM	None
Homo sapiens	SK-OV-3	GI50	25003.45	nM	None
Homo sapiens	SN12C	GI50	25003.45	nM	None
Homo sapiens	SN12K1	GI50	25003.45	nM	None
Homo sapiens	SNB-19	GI50	9311.08	nM	None
Homo sapiens	SNB-75	GI50	16826.74	nM	None
Homo sapiens	SNB-78	GI50	25003.45	nM	None
Homo sapiens	SW-620	GI50	12218.0	nM	None
Homo sapiens	TGBC11TKB	IC50	40000.0	nM	10.1021/np980504z
Homo sapiens	U-251	GI50	25003.45	nM	None
Homo sapiens	UACC-257	GI50	25003.45	nM	None
Homo sapiens	UACC-62	GI50	25003.45	nM	None
Homo sapiens	UO-31	GI50	25003.45	nM	None
Homo sapiens	XF498	GI50	25003.45	nM	None
Mus musculus	B16	IC50	40000.0	nM	10.1021/np980504z
Mus musculus	P388	GI50	25003.45	nM	None
Mus musculus	P388/ADR	GI50	25003.45	nM	None