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Amikacin

AlkaPlorer ID: AK005711

Synonym: None

IUPAC Name: (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide

Structure

SMILES: NCC[C@H](O)C(O)=N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O

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InChI: InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1

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InChIKey: LKCWBDHBTVXHDL-RMDFUYIESA-N

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Properties Information

Molecule Weight: 585.6080000000002

TPSA？: 335.42999999999995

MolLogP？: -7.583900000000006

Number of H-Donors: 13

Number of H-Acceptors: 17

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Acinetobacter Acinetobacter MIC 8.0 ug.mL-1 10.1128/aac.01115-07
Acinetobacter Acinetobacter MIC 64.0 ug.mL-1 10.1128/aac.00572-10
Acinetobacter Acinetobacter MIC nan None 10.1128/aac.01115-07
Acinetobacter baumannii Acinetobacter baumannii Activity 0.55 /hr 10.1128/aac.01468-07
Acinetobacter baumannii Acinetobacter baumannii Activity 6.62 10'8CFU/ml 10.1128/aac.01468-07
Acinetobacter baumannii Acinetobacter baumannii Activity 27.81 /hr 10.1128/aac.01468-07
Acinetobacter baumannii Acinetobacter baumannii Activity 28.6 % 10.1128/aac.00264-10
Acinetobacter baumannii Acinetobacter baumannii Activity 36.0 % 10.1128/aac.01099-06
Acinetobacter baumannii Acinetobacter baumannii Activity 36.7 % 10.1128/aac.00570-08
Acinetobacter baumannii Acinetobacter baumannii Activity 53.0 % 10.1128/aac.01581-07
Acinetobacter baumannii Acinetobacter baumannii Activity 71.4 % 10.1128/aac.00264-10
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.00560-07
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.00764-10
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.00963-09
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.01398-09
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.01468-07
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.01581-07
Acinetobacter baumannii Acinetobacter baumannii C50k 1.56 mg/L 10.1128/aac.01468-07
Acinetobacter baumannii Acinetobacter baumannii Inhibition 100.0 % 10.1021/acs.jmedchem.2c01905
Acinetobacter baumannii Acinetobacter baumannii MBC 8.0 mg/L 10.1128/aac.01468-07
Acinetobacter baumannii Acinetobacter baumannii MBC>99.9 0.125 uM 10.1021/acs.jmedchem.8b01348
Acinetobacter baumannii Acinetobacter baumannii MIC 0.5 ug.mL-1 10.1128/aac.00264-10
Acinetobacter baumannii Acinetobacter baumannii MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Acinetobacter baumannii Acinetobacter baumannii MIC 0.5 ug.mL-1 10.1128/aac.01581-07
Acinetobacter baumannii Acinetobacter baumannii MIC 0.5 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 1.0 ug.mL-1 10.1021/jm400560z
Acinetobacter baumannii Acinetobacter baumannii MIC 1.0 ug.mL-1 10.1128/aac.01259-06
Acinetobacter baumannii Acinetobacter baumannii MIC 1.5 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1021/acs.jnatprod.9b00305
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1021/acs.jnatprod.9b01000
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1039/C5MD00377F
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1039/C5MD00429B
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1128/aac.00570-08
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1128/aac.00572-10
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1128/aac.01259-06
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1128/aac.01433-06
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1128/aac.01581-07
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 3.0 ug.mL-1 10.1128/aac.01512-06
Acinetobacter baumannii Acinetobacter baumannii MIC 3.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1039/C5MD00377F
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.00178-09
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.00572-10
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.01259-06
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.01468-07
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 6.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 6.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 7.8 ug.mL-1 10.1016/j.bmc.2016.03.060
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1039/C5MD00377F
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.00861-09
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.01139-06
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.01259-06
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.01512-06
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 12.0 ug.mL-1 10.1128/aac.00570-08
Acinetobacter baumannii Acinetobacter baumannii MIC 12.0 ug.mL-1 10.1128/aac.01512-06
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1021/jm00023a011
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1039/C5MD00377F
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.00572-10
Acinetobacter baumannii Acinetobacter baumannii MIC 24.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1039/C5MD00377F
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.00838-06
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.01259-06
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 48.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1039/C5MD00429B
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.00178-09
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.00366-08
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.00572-10
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.01259-06
Acinetobacter baumannii Acinetobacter baumannii MIC 96.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 128.0 ug.mL-1 10.1021/jm1000437
Acinetobacter baumannii Acinetobacter baumannii MIC 128.0 ug.mL-1 10.1128/aac.00570-08
Acinetobacter baumannii Acinetobacter baumannii MIC 128.0 ug.mL-1 10.1128/aac.01259-06
Acinetobacter baumannii Acinetobacter baumannii MIC 128.0 ug.mL-1 10.1128/aac.01512-06
Acinetobacter baumannii Acinetobacter baumannii MIC 128.0 ug.mL-1 10.1128/aac.01581-07
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1039/d2md00459c
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00072-08
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00178-09
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00570-08
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00748-09
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.01121-08
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.01259-06
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.01512-06
Acinetobacter baumannii Acinetobacter baumannii MIC 512.0 ug.mL-1 10.1128/aac.00560-07
Acinetobacter baumannii Acinetobacter baumannii MIC 1700.0 nM 10.1021/acs.jmedchem.7b00102
Acinetobacter baumannii Acinetobacter baumannii MIC 3400.0 nM 10.1021/acs.jmedchem.7b00102
Acinetobacter baumannii Acinetobacter baumannii MIC 27000.0 nM 10.1021/acs.jmedchem.7b00102
Acinetobacter baumannii Acinetobacter baumannii MIC 31300.0 nM 10.1016/j.bmc.2016.10.009
Acinetobacter baumannii Acinetobacter baumannii MIC 50000.0 nM 10.1021/acs.jmedchem.7b00102
Acinetobacter baumannii Acinetobacter baumannii MIC50 8.0 ug.mL-1 10.1128/aac.01581-07
Acinetobacter baumannii Acinetobacter baumannii MIC50 16.0 ug.mL-1 10.1128/aac.00336-08
Acinetobacter baumannii Acinetobacter baumannii MIC50 32.0 ug.mL-1 10.1128/aac.01099-06
Acinetobacter baumannii Acinetobacter baumannii MIC50 64.0 ug.mL-1 10.1128/aac.00366-08
Acinetobacter baumannii Acinetobacter baumannii MIC50 128.0 ug.mL-1 10.1128/aac.00264-10
Acinetobacter baumannii Acinetobacter baumannii MIC90 32.0 ug.mL-1 10.1128/aac.01099-06
Acinetobacter baumannii Acinetobacter baumannii MIC90 125.0 ug.mL-1 10.1128/aac.00366-08
Acinetobacter baumannii Acinetobacter baumannii MIC90 128.0 ug.mL-1 10.1128/aac.00264-10
Acinetobacter baumannii Acinetobacter baumannii MIC90 128.0 ug.mL-1 10.1128/aac.00336-08
Acinetobacter baumannii Acinetobacter baumannii MIC90 128.0 ug.mL-1 10.1128/aac.01581-07
Acinetobacter baumannii Acinetobacter baumannii MIC90 14630.0 nM 10.1016/j.ejmech.2020.112821
Acinetobacter baumannii Acinetobacter baumannii MIC>95 0.0625 uM 10.1021/acs.jmedchem.8b01348
Acinetobacter baumannii Acinetobacter baumannii Ratio 1.0 None 10.1128/aac.00748-09
Acinetobacter calcoaceticus Acinetobacter calcoaceticus Activity 48.0 % 10.1128/aac.01400-07
Acinetobacter calcoaceticus Acinetobacter calcoaceticus Activity 98.0 % 10.1128/aac.01400-07
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC 0.25 ug.mL-1 10.1128/aac.01400-07
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC 0.5 ug.mL-1 10.1128/aac.01400-07
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC 32.0 ug.mL-1 10.1128/aac.00572-10
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC50 0.5 ug.mL-1 10.1128/aac.01400-07
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC50 16.0 ug.mL-1 10.1128/aac.01400-07
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC90 2.0 ug.mL-1 10.1128/aac.01400-07
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC90 128.0 ug.mL-1 10.1128/aac.01400-07
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.25 ug.mL-1 10.1016/j.ejmech.2018.08.022
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00818
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.5 ug.mL-1 10.1021/jm401148j
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.5 ug.mL-1 10.1021/jm900615h
Acinetobacter lwoffii Acinetobacter lwoffii MIC 2.0 ug.mL-1 10.1128/aac.00598-10
Acinetobacter lwoffii Acinetobacter lwoffii MIC 32.0 ug.mL-1 10.1021/jm00023a011
Acinetobacter lwoffii Acinetobacter lwoffii MIC 32.0 ug.mL-1 10.1128/aac.00598-10
Acinetobacter lwoffii Acinetobacter lwoffii MIC 64.0 ug.mL-1 10.1128/aac.00598-10
Acinetobacter lwoffii Acinetobacter lwoffii MIC 128.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Acinetobacter lwoffii Acinetobacter lwoffii MIC 128.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Acinetobacter lwoffii Acinetobacter lwoffii MIC 128.0 ug.mL-1 10.1021/jm401148j
Acinetobacter lwoffii Acinetobacter lwoffii MIC 128.0 ug.mL-1 10.1021/jm900615h
Acinetobacter pittii Acinetobacter pittii Activity 52.6 % 10.1128/aac.01624-09
Acinetobacter pittii Acinetobacter pittii MIC 0.5 ug.mL-1 10.1128/aac.00072-08
Acinetobacter pittii Acinetobacter pittii MIC 16.0 ug.mL-1 10.1128/aac.01624-09
Acinetobacter pittii Acinetobacter pittii MIC50 32.0 ug.mL-1 10.1128/aac.01624-09
Acinetobacter pittii Acinetobacter pittii MIC90 64.0 ug.mL-1 10.1128/aac.01624-09
Acinetobacter radioresistens Acinetobacter radioresistens MIC 0.5 ug.mL-1 10.1128/aac.00999-08
Acinetobacter sp. Acinetobacter sp. Activity 31.0 % 10.1128/aac.01808-09
Acinetobacter sp. Acinetobacter sp. MIC 32.0 ug.mL-1 10.1128/aac.00838-06
Acinetobacter sp. Acinetobacter sp. MIC50 4.0 ug.mL-1 10.1021/jm400560z
Acinetobacter sp. Acinetobacter sp. MIC50 64.0 ug.mL-1 10.1128/aac.00572-10
Acinetobacter sp. Acinetobacter sp. MIC90 64.0 ug.mL-1 10.1021/jm400560z
Acinetobacter sp. Acinetobacter sp. MIC90 64.0 ug.mL-1 10.1128/aac.00572-10
Bacillus anthracis Bacillus anthracis MIC 16.0 ug.mL-1 10.1021/acsmedchemlett.5b00255
Bacillus cereus Bacillus cereus IZ 20.0 mm 10.1007/s00044-013-0779-x
Bacillus cereus Bacillus cereus IZ 32.0 mm 10.1016/j.bmc.2015.04.015
Bacillus cereus Bacillus cereus MIC 9.4 ug.mL-1 10.1021/acsmedchemlett.5b00255
Bacillus licheniformis Bacillus licheniformis MIC 0.3 ug.mL-1 10.1021/acs.jnatprod.0c00741
Bacillus spizizenii Bacillus spizizenii MIC 72000.0 nM 10.1016/j.ejmech.2016.04.011
Bacillus subtilis Bacillus subtilis IZ 18.0 mm 10.1016/j.ejmech.2020.112832
Bacillus subtilis Bacillus subtilis IZ 21.0 mm 10.1016/j.ejmech.2011.02.039
Bacillus subtilis Bacillus subtilis IZ 32.0 mm 10.1016/j.ejmech.2008.07.017
Bacillus subtilis Bacillus subtilis Kd 760000.0 nM 10.1016/j.bmcl.2005.02.007
Bacillus subtilis Bacillus subtilis MIC 0.625 ug.mL-1 10.1016/j.bmcl.2017.03.075
Bacillus subtilis Bacillus subtilis MIC 0.9 ug.mL-1 10.1016/j.bmcl.2014.12.021
Bacillus subtilis Bacillus subtilis MIC 0.9 ug.mL-1 10.1016/j.ejmech.2010.07.038
Bacillus subtilis Bacillus subtilis MIC 0.9 ug.mL-1 10.1016/j.ejmech.2014.10.023
Bacillus subtilis Bacillus subtilis MIC 6.0 ug.mL-1 10.1016/j.ejmech.2011.02.039
Bacillus subtilis Bacillus subtilis MIC 37.5 ug.mL-1 10.1021/acsmedchemlett.5b00255
Bacillus subtilis Bacillus subtilis MIC 3900.0 nM 10.1016/j.bmc.2016.10.009
Bacillus subtilis Bacillus subtilis MIC 7000.0 nM 10.1016/j.ejmech.2021.113212
Bacillus subtilis Bacillus subtilis MIC 71720.0 nM 10.1016/j.bmc.2015.09.044
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Burkholderia cepacia Burkholderia cepacia Activity 4.0 % 10.1128/aac.00954-06
Burkholderia cepacia Burkholderia cepacia MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Burkholderia cepacia Burkholderia cepacia MIC50 128.0 ug.mL-1 10.1128/aac.00248-09
Burkholderia cepacia Burkholderia cepacia MIC90 128.0 ug.mL-1 10.1128/aac.00248-09
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Chlorocebus sabaeus Vero IC50 6.25 ug.mL-1 10.1016/j.bmcl.2017.05.050
Chlorocebus sabaeus Vero IC50 62.5 ug.mL-1 10.1016/j.bmcl.2012.12.069
Chlorocebus sabaeus Vero MNCC 6.25 ug ml-1 10.1016/j.bmc.2016.09.044
Citrobacter Citrobacter MIC50 32.0 ug.mL-1 10.1128/aac.00572-10
Citrobacter amalonaticus Citrobacter amalonaticus MIC 128.0 ug.mL-1 10.1021/jm900615h
Citrobacter amalonaticus Citrobacter amalonaticus MIC 512.0 ug.mL-1 10.1039/d2md00459c
Citrobacter freundii Citrobacter freundii Activity 31.6 % 10.1128/aac.01400-07
Citrobacter freundii Citrobacter freundii Activity 84.0 % 10.1128/aac.00426-09
Citrobacter freundii Citrobacter freundii Activity 100.0 % 10.1128/aac.01400-07
Citrobacter freundii Citrobacter freundii Activity 100.0 % 10.1128/aac.01808-09
Citrobacter freundii Citrobacter freundii MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Citrobacter freundii Citrobacter freundii MIC 0.5 ug.mL-1 10.1128/aac.01400-07
Citrobacter freundii Citrobacter freundii MIC 1.0 ug.mL-1 10.1128/aac.01099-09
Citrobacter freundii Citrobacter freundii MIC 1.0 ug.mL-1 10.1128/aac.01400-07
Citrobacter freundii Citrobacter freundii MIC 2.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 2.0 ug.mL-1 10.1128/aac.01405-06
Citrobacter freundii Citrobacter freundii MIC 4.0 ug.mL-1 10.1021/jm00023a011
Citrobacter freundii Citrobacter freundii MIC 4.0 ug.mL-1 10.1128/aac.00572-10
Citrobacter freundii Citrobacter freundii MIC 4.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 8.0 ug.mL-1 10.1128/aac.01099-09
Citrobacter freundii Citrobacter freundii MIC 30.0 ug.mL-1 10.1128/aac.00572-10
Citrobacter freundii Citrobacter freundii MIC 128.0 ug.mL-1 10.1128/aac.00886-08
Citrobacter freundii Citrobacter freundii MIC 256.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Citrobacter freundii Citrobacter freundii MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Citrobacter freundii Citrobacter freundii MIC50 2.0 ug.mL-1 10.1128/aac.01400-07
Citrobacter freundii Citrobacter freundii MIC90 4.0 ug.mL-1 10.1128/aac.01400-07
Citrobacter freundii Citrobacter freundii MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Citrobacter freundii Citrobacter freundii MIC90 32.0 ug.mL-1 10.1128/aac.01400-07
Citrobacter koseri Citrobacter koseri Activity 35.7 % 10.1128/aac.01400-07
Citrobacter koseri Citrobacter koseri Activity 100.0 % 10.1128/aac.01400-07
Citrobacter koseri Citrobacter koseri MIC 0.5 ug.mL-1 10.1128/aac.01400-07
Citrobacter koseri Citrobacter koseri MIC 1.0 ug.mL-1 10.1128/aac.01400-07
Citrobacter koseri Citrobacter koseri MIC50 1.0 ug.mL-1 10.1128/aac.01400-07
Citrobacter koseri Citrobacter koseri MIC50 32.0 ug.mL-1 10.1128/aac.01400-07
Citrobacter koseri Citrobacter koseri MIC90 2.0 ug.mL-1 10.1128/aac.01400-07
Citrobacter koseri Citrobacter koseri MIC90 64.0 ug.mL-1 10.1128/aac.01400-07
Clostridium sporogenes Clostridium sporogenes MIC 25610.0 nM 10.1016/j.bmc.2015.09.044
Clostridium sporogenes Clostridium sporogenes MIC 26000.0 nM 10.1016/j.ejmech.2016.04.011
Enterobacter Enterobacter Activity 2.0 % 10.1128/aac.01614-06
Enterobacter cloacae Enterobacter cloacae Activity 0.0 % 10.1128/aac.00675-09
Enterobacter cloacae Enterobacter cloacae Activity 0.0 % 10.1128/aac.01538-07
Enterobacter cloacae Enterobacter cloacae Activity 3.5 % 10.1128/aac.01195-06
Enterobacter cloacae Enterobacter cloacae Activity 63.2 % 10.1128/aac.01400-07
Enterobacter cloacae Enterobacter cloacae Activity 78.0 % 10.1128/aac.00675-09
Enterobacter cloacae Enterobacter cloacae Activity 92.0 % 10.1128/aac.00426-09
Enterobacter cloacae Enterobacter cloacae Activity 96.4 % 10.1128/aac.01400-07
Enterobacter cloacae Enterobacter cloacae Activity 99.0 % 10.1128/aac.01808-09
Enterobacter cloacae Enterobacter cloacae Inhibition nan % 10.1128/aac.01452-08
Enterobacter cloacae Enterobacter cloacae MBC 1.0 ug ml-1 10.1128/aac.01452-08
Enterobacter cloacae Enterobacter cloacae MBC 2.0 ug ml-1 10.1128/aac.01452-08
Enterobacter cloacae Enterobacter cloacae MBC 8.0 ug ml-1 10.1128/aac.01452-08
Enterobacter cloacae Enterobacter cloacae MIC 0.125 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 0.25 ug.mL-1 10.1128/aac.01400-07
Enterobacter cloacae Enterobacter cloacae MIC 0.5 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Enterobacter cloacae Enterobacter cloacae MIC 0.5 ug.mL-1 10.1128/aac.01099-09
Enterobacter cloacae Enterobacter cloacae MIC 0.5 ug.mL-1 10.1128/aac.01452-08
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1016/j.bmc.2016.03.060
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1021/jm00108a037
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1128/aac.01099-09
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1128/aac.01452-08
Enterobacter cloacae Enterobacter cloacae MIC 1.5 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 2.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 2.0 ug.mL-1 10.1128/aac.00572-10
Enterobacter cloacae Enterobacter cloacae MIC 2.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 2.0 ug.mL-1 10.1128/aac.01341-07
Enterobacter cloacae Enterobacter cloacae MIC 2.0 ug.mL-1 10.1128/aac.01400-07
Enterobacter cloacae Enterobacter cloacae MIC 4.0 ug.mL-1 10.1021/jm00023a011
Enterobacter cloacae Enterobacter cloacae MIC 4.0 ug.mL-1 10.1128/aac.00572-10
Enterobacter cloacae Enterobacter cloacae MIC 8.0 ug.mL-1 10.1128/aac.00726-07
Enterobacter cloacae Enterobacter cloacae MIC 16.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 16.0 ug.mL-1 10.1128/aac.00931-08
Enterobacter cloacae Enterobacter cloacae MIC 16.0 ug.mL-1 10.1128/aac.01341-07
Enterobacter cloacae Enterobacter cloacae MIC 24.0 ug.mL-1 10.1128/aac.00707-08
Enterobacter cloacae Enterobacter cloacae MIC 30.0 ug.mL-1 10.1128/aac.00572-10
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1021/jm00023a011
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.01341-07
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1039/C5MD00429B
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00260-09
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00882-08
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Enterobacter cloacae Enterobacter cloacae MIC 512.0 ug.mL-1 10.1039/d2md00459c
Enterobacter cloacae Enterobacter cloacae MIC 62500.0 nM 10.1016/j.bmc.2016.10.009
Enterobacter cloacae Enterobacter cloacae MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Enterobacter cloacae Enterobacter cloacae MIC50 2.0 ug.mL-1 10.1128/aac.01400-07
Enterobacter cloacae Enterobacter cloacae MIC50 16.0 ug.mL-1 10.1128/aac.01400-07
Enterobacter cloacae Enterobacter cloacae MIC90 4.0 ug.mL-1 10.1128/aac.01400-07
Enterobacter cloacae Enterobacter cloacae MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Enterobacter cloacae Enterobacter cloacae MIC90 32.0 ug.mL-1 10.1128/aac.01400-07
Enterobacter cloacae Enterobacter cloacae MIC90 nan None 10.1016/j.ejmech.2020.112821
Enterobacter hormaechei Enterobacter hormaechei MIC 0.2 ug.mL-1 10.1021/acs.jnatprod.0c00741
Enterobacter hormaechei Enterobacter hormaechei MIC 4.0 ug.mL-1 10.1128/aac.01592-08
Enterobacter hormaechei Enterobacter hormaechei MIC 8.0 ug.mL-1 10.1128/aac.01592-08
Enterobacteriaceae Enterobacteriaceae Activity 4.2 % 10.1128/aac.00044-07
Enterobacteriaceae Enterobacteriaceae Activity 8.3 % 10.1128/aac.01114-07
Enterobacteriaceae Enterobacteriaceae Activity 29.7 % 10.1128/aac.00044-07
Enterobacteriaceae Enterobacteriaceae Activity 73.3 % 10.1128/aac.01114-07
Enterobacteriaceae Enterobacteriaceae MIC50 2.0 ug.mL-1 10.1128/aac.01450-09
Enterobacteriaceae Enterobacteriaceae MIC50 4.0 ug.mL-1 10.1128/aac.01450-09
Enterobacteriaceae Enterobacteriaceae MIC50 8.0 ug.mL-1 10.1128/aac.01114-07
Enterobacteriaceae Enterobacteriaceae MIC50 8.0 ug.mL-1 10.1128/aac.01450-09
Enterobacteriaceae Enterobacteriaceae MIC50 256.0 ug.mL-1 10.1128/aac.00748-08
Enterobacteriaceae Enterobacteriaceae MIC90 8.0 ug.mL-1 10.1128/aac.01450-09
Enterobacteriaceae Enterobacteriaceae MIC90 32.0 ug.mL-1 10.1128/aac.01114-07
Enterobacteriaceae Enterobacteriaceae MIC90 64.0 ug.mL-1 10.1128/aac.01450-09
Enterobacteriaceae Enterobacteriaceae MIC90 256.0 ug.mL-1 10.1128/aac.00748-08
Enterobacter sp. Enterobacter sp. Activity 4.8 % 10.1128/aac.01114-07
Enterobacter sp. Enterobacter sp. Activity 95.2 % 10.1128/aac.01114-07
Enterobacter sp. Enterobacter sp. MIC50 2.0 ug.mL-1 10.1128/aac.01114-07
Enterobacter sp. Enterobacter sp. MIC50 8.0 ug.mL-1 10.1128/aac.00572-10
Enterobacter sp. Enterobacter sp. MIC90 16.0 ug.mL-1 10.1128/aac.01114-07
Enterobacter sp. Enterobacter sp. MIC90 64.0 ug.mL-1 10.1128/aac.00572-10
Enterococcus Enterococcus Activity nan None 10.1016/j.bmc.2016.10.009
Enterococcus Enterococcus MIC 62.5 ug.mL-1 10.1016/j.bmc.2016.03.060
Enterococcus Enterococcus MIC 125000.0 nM 10.1016/j.bmc.2016.10.009
Enterococcus faecalis Enterococcus faecalis Activity nan None 10.1128/aac.01400-07
Enterococcus faecalis Enterococcus faecalis IZ 23.0 mm 10.1016/j.ejmech.2008.07.017
Enterococcus faecalis Enterococcus faecalis MIC 0.39 ug.mL-1 10.1016/j.bmcl.2017.03.075
Enterococcus faecalis Enterococcus faecalis MIC 2.0 ug.mL-1 10.1016/j.ejmech.2009.12.016
Enterococcus faecalis Enterococcus faecalis MIC 4.0 ug.mL-1 10.1016/j.ejmech.2009.12.016
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1016/j.bmc.2010.11.001
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1016/j.bmcl.2010.12.084
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1021/jm800997s
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1128/aac.01400-07
Enterococcus faecalis Enterococcus faecalis MIC 64.0 ug.mL-1 10.1016/j.bmcl.2005.08.032
Enterococcus faecalis Enterococcus faecalis MIC 64.0 ug.mL-1 10.1021/jm00023a011
Enterococcus faecalis Enterococcus faecalis MIC 64.0 ug.mL-1 10.1128/aac.00603-06
Enterococcus faecalis Enterococcus faecalis MIC 125.0 ug.mL-1 10.1016/j.bmc.2016.03.060
Enterococcus faecalis Enterococcus faecalis MIC 128.0 ug.mL-1 10.1016/j.bmcl.2010.12.084
Enterococcus faecalis Enterococcus faecalis MIC 250.0 ug.mL-1 10.1016/j.bmc.2010.11.001
Enterococcus faecalis Enterococcus faecalis MIC 250.0 ug.mL-1 10.1016/j.ejmech.2016.12.008
Enterococcus faecalis Enterococcus faecalis MIC 250.0 ug.mL-1 10.1021/jm800997s
Enterococcus faecalis Enterococcus faecalis MIC 250.0 ug.mL-1 10.1039/c4md00078a
Enterococcus faecalis Enterococcus faecalis MIC 256.0 ug.mL-1 10.1016/j.bmcl.2015.11.095
Enterococcus faecalis Enterococcus faecalis MIC nan None 10.1021/acs.jmedchem.5b01620
Enterococcus faecalis Enterococcus faecalis MIC50 128.0 ug.mL-1 10.1128/aac.01400-07
Enterococcus faecalis Enterococcus faecalis MIC90 128.0 ug.mL-1 10.1128/aac.01400-07
Enterococcus faecium Enterococcus faecium MIC 125.0 ug.mL-1 10.1016/j.bmc.2016.03.060
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.00063-08
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.00551-10
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.00675-09
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.01538-07
Escherichia coli Escherichia coli Activity 1.0 % 10.1128/aac.00061-09
Escherichia coli Escherichia coli Activity 3.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 4.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity 5.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 6.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 7.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity 8.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 11.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 12.5 % 10.1128/aac.00171-08
Escherichia coli Escherichia coli Activity 17.0 % 10.1128/aac.00675-09
Escherichia coli Escherichia coli Activity 31.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 32.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 34.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 35.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 35.0 % 10.1128/aac.01338-09
Escherichia coli Escherichia coli Activity 36.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 37.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 39.0 % 10.1128/aac.01338-09
Escherichia coli Escherichia coli Activity 44.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 45.0 % 10.1128/aac.01338-09
Escherichia coli Escherichia coli Activity 46.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 48.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 53.7 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 59.5 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 69.0 % 10.1128/aac.00892-06
Escherichia coli Escherichia coli Activity 71.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity 78.9 % 10.1128/aac.00171-08
Escherichia coli Escherichia coli Activity 81.0 % 10.1128/aac.00171-08
Escherichia coli Escherichia coli Activity 83.3 % 10.1128/aac.00171-08
Escherichia coli Escherichia coli Activity 87.0 % 10.1128/aac.00426-09
Escherichia coli Escherichia coli Activity 93.0 % 10.1128/aac.01400-07
Escherichia coli Escherichia coli Activity 97.0 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 98.0 % 10.1128/aac.00426-09
Escherichia coli Escherichia coli Activity 98.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity 98.1 % 10.1128/aac.01509-06
Escherichia coli Escherichia coli Activity 98.5 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 100.0 % 10.1128/aac.00675-09
Escherichia coli Escherichia coli Activity 100.0 % 10.1128/aac.01400-07
Escherichia coli Escherichia coli Activity 100.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00014-10
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00560-07
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00892-06
Escherichia coli Escherichia coli Inhibition nan % 10.1128/aac.00014-10
Escherichia coli Escherichia coli Inhibition nan % 10.1128/aac.01452-08
Escherichia coli Escherichia coli IZ 14.0 mm 10.1016/j.ejmech.2011.07.013
Escherichia coli Escherichia coli IZ 16.2 mm 10.1016/j.ejmech.2011.07.013
Escherichia coli Escherichia coli IZ 17.0 mm 10.1007/s00044-011-9729-7
Escherichia coli Escherichia coli IZ 17.0 mm 10.1016/j.ejmech.2020.112832
Escherichia coli Escherichia coli IZ 18.0 mm 10.1016/j.bmcl.2011.04.117
Escherichia coli Escherichia coli IZ 20.0 mm 10.1016/j.bmcl.2016.09.059
Escherichia coli Escherichia coli IZ 20.0 mm 10.1016/j.ejmech.2011.07.013
Escherichia coli Escherichia coli IZ 21.27 mm 10.1007/s00044-011-9708-z
Escherichia coli Escherichia coli IZ 22.0 mm 10.1016/j.bmc.2015.04.015
Escherichia coli Escherichia coli IZ 22.0 mm 10.1016/j.ejmech.2011.02.039
Escherichia coli Escherichia coli IZ 30.0 mm 10.1016/j.ejmech.2008.07.017
Escherichia coli Escherichia coli MBC 0.006 mM 10.1016/j.ejmech.2008.07.017
Escherichia coli Escherichia coli MBC 4.0 ug ml-1 10.1128/aac.01452-08
Escherichia coli Escherichia coli MBC 16.0 ug ml-1 10.1128/aac.01452-08
Escherichia coli Escherichia coli MBC>99.9 0.0625 uM 10.1021/acs.jmedchem.8b01348
Escherichia coli Escherichia coli MBC>99.9 0.125 uM 10.1021/acs.jmedchem.8b01348
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 0.13 ug.mL-1 10.1128/aac.00926-07
Escherichia coli Escherichia coli MIC 0.15 ug.mL-1 10.1128/aac.00748-09
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01400-08
Escherichia coli Escherichia coli MIC 0.312 ug.mL-1 10.1016/j.bmcl.2017.03.075
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.bmcl.2010.12.084
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1039/C5MD00429B
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00572-10
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00616-07
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00726-07
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00795-06
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00838-06
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00896-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00926-07
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01345-06
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01400-07
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01400-08
Escherichia coli Escherichia coli MIC 0.75 ug.mL-1 10.1128/aac.00465-08
Escherichia coli Escherichia coli MIC 0.75 ug.mL-1 10.1128/aac.00810-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.bmc.2010.11.001
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.bmcl.2005.08.032
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.bmcl.2010.09.084
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.bmcl.2011.08.095
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.ejmech.2009.03.006
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.ejmech.2016.12.008
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1021/jm800997s
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1039/c4md00078a
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00137-10
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00336-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00436-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00726-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00748-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00830-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00882-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01053-06
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01360-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01452-08
Escherichia coli Escherichia coli MIC 1.5 ug.mL-1 10.1128/aac.00436-09
Escherichia coli Escherichia coli MIC 1.5 ug.mL-1 10.1128/aac.00810-07
Escherichia coli Escherichia coli MIC 1.5 ug.mL-1 10.1128/aac.00882-08
Escherichia coli Escherichia coli MIC 1.9 ug.mL-1 10.1016/j.bmcl.2014.12.021
Escherichia coli Escherichia coli MIC 1.9 ug.mL-1 10.1016/j.ejmech.2010.07.038
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmc.2016.03.060
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmcl.2010.09.084
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.ejmech.2012.01.031
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.ejmech.2019.02.024
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/acs.jnatprod.7b00077
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/jm00023a011
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/jm00108a037
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/jm1000437
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/jm401148j
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/jm900615h
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1039/C5MD00429B
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00158-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00299-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00572-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00616-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00726-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00748-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00780-06
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00830-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00896-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01137-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01341-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01444-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01452-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01818-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.7b00204
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1021/acs.jnatprod.9b00305
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1021/acs.jnatprod.9b01000
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1021/jm00108a037
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1021/jm1000437
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1021/jm401148j
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1021/jm900615h
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1039/C5MD00429B
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00572-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00616-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00726-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00780-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00795-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00830-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00899-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 6.0 ug.mL-1 10.1016/j.ejmech.2011.02.039
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.bmcl.2010.09.084
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.ejmech.2019.02.024
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1021/jm00023a011
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1021/jm00108a037
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00830-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00838-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01452-08
Escherichia coli Escherichia coli MIC 12.0 ug.mL-1 10.1128/aac.00944-09
Escherichia coli Escherichia coli MIC 12.0 ug.mL-1 10.1128/aac.01034-06
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00158-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00896-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00926-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01360-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01444-09
Escherichia coli Escherichia coli MIC 30.0 ug.mL-1 10.1128/aac.00572-10
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/jm1000437
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/jm900615h
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00572-10
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00926-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01360-08
Escherichia coli Escherichia coli MIC 48.0 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 50.0 ug.mL-1 10.1016/j.bmcl.2009.09.095
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.bmcl.2010.09.084
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1021/jm401148j
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1039/C5MD00429B
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00572-10
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1016/j.bmcl.2015.11.095
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1021/jm00023a011
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1021/jm900615h
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01137-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01320-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1021/jm00108a037
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00137-10
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00560-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00882-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00926-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01320-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01345-06
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1016/j.bmcl.2015.11.095
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1039/d2md00459c
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00143-07
Escherichia coli Escherichia coli MIC 3000.0 nM 10.1016/j.ejmech.2008.07.017
Escherichia coli Escherichia coli MIC 8540.0 nM 10.1016/j.bmc.2015.09.044
Escherichia coli Escherichia coli MIC 9000.0 nM 10.1016/j.ejmech.2016.04.011
Escherichia coli Escherichia coli MIC 31300.0 nM 10.1016/j.bmc.2016.10.009
Escherichia coli Escherichia coli MIC nan ug.mL-1 10.1021/jm00108a037
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.01011-08
Escherichia coli Escherichia coli MIC50 1.0 ug.mL-1 10.1021/jm400560z
Escherichia coli Escherichia coli MIC50 1.0 ug.mL-1 10.1128/aac.01400-07
Escherichia coli Escherichia coli MIC50 1.71 mmol/ml 10.1016/j.ejmech.2010.02.023
Escherichia coli Escherichia coli MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Escherichia coli Escherichia coli MIC50 2.0 ug.mL-1 10.1128/aac.01509-06
Escherichia coli Escherichia coli MIC50 8.0 ug.mL-1 10.1021/jm400560z
Escherichia coli Escherichia coli MIC50 8.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC50 16.0 ug.mL-1 10.1128/aac.00572-10
Escherichia coli Escherichia coli MIC90 2.0 ug.mL-1 10.1128/aac.01400-07
Escherichia coli Escherichia coli MIC90 4.0 ug.mL-1 10.1128/aac.00336-08
Escherichia coli Escherichia coli MIC90 4.0 ug.mL-1 10.1128/aac.01400-07
Escherichia coli Escherichia coli MIC90 8.0 ug.mL-1 10.1128/aac.01509-06
Escherichia coli Escherichia coli MIC90 16.0 ug.mL-1 10.1021/jm400560z
Escherichia coli Escherichia coli MIC90 16.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1021/jm400560z
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1128/aac.00572-10
Escherichia coli Escherichia coli MIC90 64.0 ug.mL-1 10.1021/jm400560z
Escherichia coli Escherichia coli MIC>95 0.0625 uM 10.1021/acs.jmedchem.8b01348
Escherichia coli Escherichia coli Ratio 2.0 None 10.1128/aac.00748-09
Escherichia coli K-12 Cell division protein ftsZ Activity 35.0 % 10.1016/j.ejmech.2015.03.026
Haemophilus influenzae Haemophilus influenzae Activity nan None 10.1128/aac.01400-07
Haemophilus influenzae Haemophilus influenzae Activity nan None 10.1128/aac.01538-07
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1128/aac.01400-07
Haemophilus influenzae Haemophilus influenzae MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Haemophilus influenzae Haemophilus influenzae MIC 37.5 ug.mL-1 10.1021/acsmedchemlett.5b00255
Haemophilus influenzae Haemophilus influenzae MIC50 8.0 ug.mL-1 10.1128/aac.01400-07
Haemophilus influenzae Haemophilus influenzae MIC90 16.0 ug.mL-1 10.1128/aac.01400-07
Haemophilus parainfluenzae Haemophilus parainfluenzae Activity nan None 10.1128/aac.01400-07
Haemophilus parainfluenzae Haemophilus parainfluenzae MIC 2.0 ug.mL-1 10.1128/aac.01400-07
Haemophilus parainfluenzae Haemophilus parainfluenzae MIC50 4.0 ug.mL-1 10.1128/aac.01400-07
Haemophilus parainfluenzae Haemophilus parainfluenzae MIC90 8.0 ug.mL-1 10.1128/aac.01400-07
Homo sapiens 5637 Activity nan None 10.1128/aac.00014-10
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens Adenosine A1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Alpha-1a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1d adrenergic receptor IC50 nan None None
Homo sapiens Alpha-1d adrenergic receptor Ki nan None None
Homo sapiens Alpha-2a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2a adrenergic receptor Ki nan None None
Homo sapiens Alpha-2b adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2b adrenergic receptor Ki nan None None
Homo sapiens Alpha-2c adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2c adrenergic receptor Ki nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens Beta-1 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bile salt export pump IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Bile salt export pump IC50 135000.0 nM 10.1093/toxsci/kfq269
Homo sapiens Bradykinin B2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Canalicular multispecific organic anion transporter 2 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Cannabinoid CB1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens Cholecystokinin A receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 3A4 IC50 nan None None
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens Dopamine D1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor IC50 nan None None
Homo sapiens Dopamine D1 receptor Ki nan None None
Homo sapiens Dopamine D2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor IC50 nan None None
Homo sapiens Dopamine D2 receptor Ki nan None None
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor IC50 nan None None
Homo sapiens Dopamine D3 receptor Ki nan None None
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens Ghrelin receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 nan None None
Homo sapiens HERG Ki nan None None
Homo sapiens Histamine H1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor IC50 nan None None
Homo sapiens Histamine H1 receptor Ki nan None None
Homo sapiens Histamine H2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor IC50 nan None None
Homo sapiens Histamine H2 receptor Ki nan None None
Homo sapiens Histone acetyltransferase GCN5 Potency 31622.8 nM None
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens Cmax 341.52 nM 10.1128/aac.01099-07
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 0.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens Drug uptake 7.68 nmol/mg 10.1128/aac.01680-07
Homo sapiens Homo sapiens Drug uptake 25.6 umol/Kg 10.1128/aac.01680-07
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens Kappa opioid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens Melanocortin receptor 3 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens Monoamine oxidase A AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Motilin receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Multidrug resistance-associated protein 4 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki nan None None
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor IC50 nan None None
Homo sapiens Neurokinin 2 receptor Ki nan None None
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Norepinephrine transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter IC50 nan None None
Homo sapiens Norepinephrine transporter Ki nan None None
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Pregnane X receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Prelamin-A/C Potency 158.5 nM None
Homo sapiens Progesterone receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki nan None None
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki nan None None
Homo sapiens Serotonin transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter IC50 nan None None
Homo sapiens Serotonin transporter Ki nan None None
Homo sapiens Serum Cmax 60962.07 nM 10.1128/aac.01099-07
Homo sapiens Serum Cmin 3.8 mg/L 10.1128/aac.01099-07
Homo sapiens Sigma opioid receptor IC50 nan None None
Homo sapiens Sigma opioid receptor Ki nan None None
Homo sapiens Telomerase reverse transcriptase Inhibition 25.0 % 10.1016/j.bmcl.2004.04.055
Homo sapiens Telomerase reverse transcriptase Inhibition nan % 10.1016/j.bmcl.2004.04.055
Homo sapiens Thromboxane A2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Type-1 angiotensin II receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine-protein kinase FYN IC50 nan None None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Homo sapiens Vasopressin V2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Klebsiella aerogenes Klebsiella aerogenes Activity 55.0 % 10.1128/aac.01400-07
Klebsiella aerogenes Klebsiella aerogenes Activity 83.0 % 10.1128/aac.00426-09
Klebsiella aerogenes Klebsiella aerogenes Activity 100.0 % 10.1128/aac.01400-07
Klebsiella aerogenes Klebsiella aerogenes Activity 100.0 % 10.1128/aac.01808-09
Klebsiella aerogenes Klebsiella aerogenes MIC 0.03 ug.mL-1 10.1128/aac.01400-07
Klebsiella aerogenes Klebsiella aerogenes MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Klebsiella aerogenes Klebsiella aerogenes MIC 1.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella aerogenes Klebsiella aerogenes MIC 1.0 ug.mL-1 10.1128/aac.01400-07
Klebsiella aerogenes Klebsiella aerogenes MIC 4.0 ug.mL-1 10.1128/aac.00572-10
Klebsiella aerogenes Klebsiella aerogenes MIC 30.0 ug.mL-1 10.1128/aac.00572-10
Klebsiella aerogenes Klebsiella aerogenes MIC 128.0 ug.mL-1 10.1021/jm900615h
Klebsiella aerogenes Klebsiella aerogenes MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella aerogenes Klebsiella aerogenes MIC 512.0 ug.mL-1 10.1039/d2md00459c
Klebsiella aerogenes Klebsiella aerogenes MIC50 1.0 ug.mL-1 10.1128/aac.01400-07
Klebsiella aerogenes Klebsiella aerogenes MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Klebsiella aerogenes Klebsiella aerogenes MIC50 16.0 ug.mL-1 10.1128/aac.01400-07
Klebsiella aerogenes Klebsiella aerogenes MIC90 2.0 ug.mL-1 10.1128/aac.01400-07
Klebsiella aerogenes Klebsiella aerogenes MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Klebsiella aerogenes Klebsiella aerogenes MIC90 64.0 ug.mL-1 10.1128/aac.01400-07
Klebsiella aerogenes Klebsiella aerogenes MIC90 nan None 10.1016/j.ejmech.2020.112821
Klebsiella oxytoca Klebsiella oxytoca Activity 86.0 % 10.1128/aac.00426-09
Klebsiella oxytoca Klebsiella oxytoca Activity 100.0 % 10.1128/aac.00426-09
Klebsiella oxytoca Klebsiella oxytoca Activity 100.0 % 10.1128/aac.01808-09
Klebsiella oxytoca Klebsiella oxytoca MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Klebsiella oxytoca Klebsiella oxytoca MIC 2.0 ug.mL-1 10.1128/aac.00260-09
Klebsiella oxytoca Klebsiella oxytoca MIC 4.0 ug.mL-1 10.1128/aac.00572-10
Klebsiella oxytoca Klebsiella oxytoca MIC 4.0 ug.mL-1 10.1128/aac.01355-08
Klebsiella oxytoca Klebsiella oxytoca MIC 30.0 ug.mL-1 10.1128/aac.00572-10
Klebsiella oxytoca Klebsiella oxytoca MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Klebsiella oxytoca Klebsiella oxytoca MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 0.0 % 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 0.0 % 10.1128/aac.00675-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 0.0 % 10.1128/aac.01538-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity 1.9 % 10.1128/aac.01538-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity 2.4 % 10.1128/aac.01538-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity 2.6 % 10.1128/aac.01538-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity 4.9 % 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 6.7 % 10.1128/aac.01538-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity 20.0 % 10.1128/aac.00675-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 28.6 % 10.1128/aac.00171-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 48.0 % 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 50.0 % 10.1128/aac.00675-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 66.0 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 69.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 73.0 % 10.1128/aac.00426-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 75.0 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 78.4 % 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 78.9 % 10.1128/aac.00171-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 81.0 % 10.1128/aac.00171-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 82.1 % 10.1128/aac.01400-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity 83.3 % 10.1128/aac.00171-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 91.4 % 10.1128/aac.01509-06
Klebsiella pneumoniae Klebsiella pneumoniae Activity 92.7 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 95.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 98.6 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 99.0 % 10.1128/aac.00426-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 100.0 % 10.1128/aac.01400-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity 100.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 102.0 % 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 106.0 % 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae Inhibition nan % 10.1128/aac.01452-08
Klebsiella pneumoniae Klebsiella pneumoniae IZ 11.0 mm 10.1007/s00044-013-0779-x
Klebsiella pneumoniae Klebsiella pneumoniae IZ 21.0 mm 10.1016/j.ejmech.2011.02.039
Klebsiella pneumoniae Klebsiella pneumoniae IZ 23.0 mm 10.1016/j.bmcl.2016.09.059
Klebsiella pneumoniae Klebsiella pneumoniae IZ 25.0 mm 10.1016/j.ejmech.2008.07.017
Klebsiella pneumoniae Klebsiella pneumoniae MBC 0.009 mM 10.1016/j.ejmech.2008.07.017
Klebsiella pneumoniae Klebsiella pneumoniae MBC 1.0 ug ml-1 10.1128/aac.01452-08
Klebsiella pneumoniae Klebsiella pneumoniae MBC 2.0 ug ml-1 10.1128/aac.01452-08
Klebsiella pneumoniae Klebsiella pneumoniae MBC>99.9 0.125 uM 10.1021/acs.jmedchem.8b01348
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1021/jm401148j
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1021/jm800997s
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1021/jm900615h
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1039/C5MD00429B
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00572-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01400-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.bmc.2010.11.001
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.bmc.2016.03.060
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.bmcl.2005.08.032
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.ejmech.2009.03.006
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.ejmech.2016.12.008
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1021/jm800997s
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00083-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00260-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00336-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01355-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01452-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.5 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1016/j.bmcl.2011.08.095
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1021/jm00023a011
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1021/jm00108a037
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00158-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00260-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00299-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00572-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00886-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01355-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01452-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01672-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01818-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00299-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00572-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01818-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 5.0 ug.mL-1 10.1016/j.bmcl.2017.03.075
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.0 ug.mL-1 10.1016/j.ejmech.2011.02.039
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1021/acs.jnatprod.9b00305
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1021/acs.jnatprod.9b01000
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01818-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 12.0 ug.mL-1 10.1128/aac.00436-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1016/j.ejmech.2019.02.024
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00299-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00726-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01355-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01672-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01818-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 30.0 ug.mL-1 10.1128/aac.00572-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1016/j.bmcl.2010.12.084
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1016/j.ejmech.2019.02.024
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1021/jm00023a011
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01355-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01818-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1021/jm400560z
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00158-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00299-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01355-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01818-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00886-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00137-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00260-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00882-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01053-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1039/d2md00459c
Klebsiella pneumoniae Klebsiella pneumoniae MIC 3000.0 nM 10.1016/j.ejmech.2008.07.017
Klebsiella pneumoniae Klebsiella pneumoniae MIC 31300.0 nM 10.1016/j.bmc.2016.10.009
Klebsiella pneumoniae Klebsiella pneumoniae MIC nan ug.mL-1 10.1021/jm00108a037
Klebsiella pneumoniae Klebsiella pneumoniae MIC nan None 10.1021/jm400560z
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.00336-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01400-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 1.71 mmol/ml 10.1016/j.ejmech.2010.02.023
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01509-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 4.0 ug.mL-1 10.1021/jm400560z
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.00083-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 6.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 16.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 32.0 ug.mL-1 10.1021/jm400560z
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 32.0 ug.mL-1 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 32.0 ug.mL-1 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 48.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 256.0 ug.mL-1 10.1128/aac.00083-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01400-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 12.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.01509-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.00083-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 64.0 ug.mL-1 10.1021/jm400560z
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 96.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 128.0 ug.mL-1 10.1128/aac.01400-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 256.0 ug.mL-1 10.1128/aac.00083-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 nan None 10.1016/j.ejmech.2020.112821
Klebsiella pneumoniae Klebsiella pneumoniae MIC>95 0.0625 uM 10.1021/acs.jmedchem.8b01348
Klebsiella sp. Klebsiella sp. Activity 13.3 % 10.1128/aac.01114-07
Klebsiella sp. Klebsiella sp. Activity 53.3 % 10.1128/aac.01114-07
Klebsiella sp. Klebsiella sp. MIC50 16.0 ug.mL-1 10.1128/aac.01114-07
Klebsiella sp. Klebsiella sp. MIC50 32.0 ug.mL-1 10.1128/aac.00572-10
Klebsiella sp. Klebsiella sp. MIC90 32.0 ug.mL-1 10.1128/aac.01114-07
Klebsiella sp. Klebsiella sp. MIC90 64.0 ug.mL-1 10.1128/aac.00572-10
Kocuria rhizophila Kocuria rhizophila MIC 3000.0 nM 10.1016/j.ejmech.2016.04.011
Kocuria rhizophila Kocuria rhizophila MIC 3420.0 nM 10.1016/j.bmc.2015.09.044
Listeria monocytogenes Listeria monocytogenes Activity nan None 10.1016/j.bmc.2016.10.009
Listeria monocytogenes Listeria monocytogenes IZ 20.0 mm 10.1016/j.ejmech.2011.02.039
Listeria monocytogenes Listeria monocytogenes MIC 3.9 ug.mL-1 10.1016/j.bmc.2016.03.060
Listeria monocytogenes Listeria monocytogenes MIC 6.0 ug.mL-1 10.1016/j.ejmech.2011.02.039
Listeria monocytogenes Listeria monocytogenes MIC 9.4 ug.mL-1 10.1021/acsmedchemlett.5b00255
Listeria monocytogenes Listeria monocytogenes MIC 3900.0 nM 10.1016/j.bmc.2016.10.009
Micrococcus flavus Micrococcus flavus MIC 3420.0 nM 10.1016/j.bmc.2015.09.044
Micrococcus luteus Micrococcus luteus IZ 31.0 mm 10.1016/j.ejmech.2008.07.017
Micrococcus luteus Micrococcus luteus MIC 0.39 ug.mL-1 10.1016/j.bmcl.2017.03.075
Micrococcus luteus Micrococcus luteus MIC 1000.0 nM 10.1016/j.ejmech.2021.113212
Micrococcus luteus Micrococcus luteus MIC 3000.0 nM 10.1016/j.ejmech.2016.04.011
Micrococcus luteus Micrococcus luteus MIC 13650.0 nM 10.1016/j.bmc.2015.09.044
Micrococcus luteus Micrococcus luteus MIC 14000.0 nM 10.1016/j.ejmech.2016.04.011
Morganella morganii Morganella morganii Activity 83.3 % 10.1128/aac.01400-07
Morganella morganii Morganella morganii Activity 96.0 % 10.1128/aac.01400-07
Morganella morganii Morganella morganii Activity 100.0 % 10.1128/aac.00675-09
Morganella morganii Morganella morganii MIC 0.5 ug.mL-1 10.1128/aac.01400-07
Morganella morganii Morganella morganii MIC 1.0 ug.mL-1 10.1128/aac.00336-08
Morganella morganii Morganella morganii MIC 1.0 ug.mL-1 10.1128/aac.01400-07
Morganella morganii Morganella morganii MIC50 1.0 ug.mL-1 10.1128/aac.01400-07
Morganella morganii Morganella morganii MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Morganella morganii Morganella morganii MIC90 2.0 ug.mL-1 10.1128/aac.01400-07
Morganella morganii Morganella morganii MIC90 4.0 ug.mL-1 10.1128/aac.00336-08
Morganella morganii Morganella morganii MIC90 4.0 ug.mL-1 10.1128/aac.01400-07
Mus musculus J774 Activity 81.2 % 10.1016/j.ejmech.2018.08.022
Mus musculus J774 Activity 92.0 % 10.1016/j.ejmech.2018.08.022
Mus musculus Mus musculus Activity 81.2 % 10.1021/acs.jmedchem.6b00818
Mus musculus Mus musculus Activity 92.0 % 10.1021/acs.jmedchem.6b00818
Mus musculus Mus musculus LD50 300.0 mg.kg-1 10.1016/j.bmc.2017.02.068
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Mycobacterium avium Mycobacterium avium log10cfu 3.5 None 10.1128/aac.00689-09
Mycobacterium avium Mycobacterium avium log10cfu 5.9 None 10.1128/aac.00689-09
Mycobacterium avium Mycobacterium avium log10cfu 6.7 None 10.1128/aac.00689-09
Mycobacterium avium Mycobacterium avium log10cfu 7.2 None 10.1128/aac.00689-09
Mycobacterium avium Mycobacterium avium MIC 1.56 ug.mL-1 10.1016/j.bmcl.2009.09.095
Mycobacterium avium Mycobacterium avium MIC 100.0 ug.mL-1 10.1016/j.bmcl.2009.09.095
Mycobacterium leprae Mycobacterium leprae Activity 96.0 % 10.1016/j.bmc.2019.04.032
Mycobacterium leprae Mycobacterium leprae Activity 97.3 % 10.1016/j.bmc.2019.04.032
Mycobacterium marinum Mycobacterium marinum Activity nan None 10.1021/acs.jmedchem.5b01620
Mycobacterium marinum Mycobacterium marinum MIC 1700.0 nM 10.1021/acs.jmedchem.5b01620
Mycobacterium marinum Mycobacterium marinum MIC50 0.62 ug.mL-1 10.1016/j.bmcl.2022.128692
Mycobacterium marinum Mycobacterium marinum MIC90 1.7 ug.mL-1 10.1016/j.bmcl.2022.128692
Mycobacterium marinum Mycobacterium marinum MIC90 3660.0 nM 10.1016/j.ejmech.2020.112821
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1016/j.bmc.2016.09.044
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1128/aac.00661-10
Mycobacterium tuberculosis Mycobacterium tuberculosis EC50 70.0 nM 10.1016/j.bmcl.2012.12.069
Mycobacterium tuberculosis Mycobacterium tuberculosis EC50 70.0 nM 10.1016/j.bmcl.2014.01.007
Mycobacterium tuberculosis Mycobacterium tuberculosis EC50 120.0 nM 10.1016/j.bmcl.2012.12.069
Mycobacterium tuberculosis Mycobacterium tuberculosis EC90 0.08 uM 10.1016/j.bmcl.2014.01.007
Mycobacterium tuberculosis Mycobacterium tuberculosis EC90 0.12 uM 10.1016/j.bmcl.2012.12.069
Mycobacterium tuberculosis Mycobacterium tuberculosis EC90 0.14 uM 10.1016/j.bmcl.2012.12.069
Mycobacterium tuberculosis Mycobacterium tuberculosis IC50 0.07 ug.mL-1 10.1016/j.ejmech.2013.09.061
Mycobacterium tuberculosis Mycobacterium tuberculosis IC50 70.0 nM 10.1016/j.bmc.2016.09.044
Mycobacterium tuberculosis Mycobacterium tuberculosis IC50 70.0 nM 10.1016/j.bmcl.2017.05.050
Mycobacterium tuberculosis Mycobacterium tuberculosis IC50 70.0 nM 10.1016/j.ejmech.2013.12.013
Mycobacterium tuberculosis Mycobacterium tuberculosis IC50 70.0 nM 10.1016/j.ejmech.2014.08.009
Mycobacterium tuberculosis Mycobacterium tuberculosis IC50 80.0 nM 10.1016/j.ejmech.2017.11.035
Mycobacterium tuberculosis Mycobacterium tuberculosis IC50 102.0 nM 10.1016/j.bmcl.2016.03.066
Mycobacterium tuberculosis Mycobacterium tuberculosis IC90 0.08 ug.mL-1 10.1016/j.ejmech.2013.09.061
Mycobacterium tuberculosis Mycobacterium tuberculosis IC90 80.0 nM 10.1016/j.bmc.2016.09.044
Mycobacterium tuberculosis Mycobacterium tuberculosis IC90 80.0 nM 10.1016/j.bmcl.2017.05.050
Mycobacterium tuberculosis Mycobacterium tuberculosis IC90 80.0 nM 10.1016/j.ejmech.2013.12.013
Mycobacterium tuberculosis Mycobacterium tuberculosis IC90 80.0 nM 10.1016/j.ejmech.2014.08.009
Mycobacterium tuberculosis Mycobacterium tuberculosis IC90 90.0 nM 10.1016/j.ejmech.2017.11.035
Mycobacterium tuberculosis Mycobacterium tuberculosis IC90 141.0 nM 10.1016/j.bmcl.2016.03.066
Mycobacterium tuberculosis Mycobacterium tuberculosis Inhibition 30.0 % 10.1016/j.bmc.2016.09.044
Mycobacterium tuberculosis Mycobacterium tuberculosis Inhibition 79.8 % 10.1016/j.ejmech.2013.09.061
Mycobacterium tuberculosis Mycobacterium tuberculosis Inhibition 96.0 % 10.1016/j.ejmech.2013.09.061
Mycobacterium tuberculosis Mycobacterium tuberculosis Inhibition 97.3 % 10.1016/j.ejmech.2013.09.061
Mycobacterium tuberculosis Mycobacterium tuberculosis Inhibition 98.0 % 10.1016/j.ejmech.2013.09.061
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.12 ug.mL-1 10.1016/j.ejmech.2017.06.005
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.14 ug.mL-1 10.1021/acsmedchemlett.1c00431
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.32 ug.mL-1 10.1021/acsmedchemlett.1c00431
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.5 ug.mL-1 10.1128/aac.00661-10
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1.75 ug.mL-1 10.1016/j.bmcl.2009.09.095
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 2.0 ug.mL-1 10.1016/j.ejmech.2009.04.002
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 2.0 ug.mL-1 10.1016/j.ejmech.2015.10.054
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 4.0 ug.mL-1 10.1039/C9MD00057G
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 5.0 ug.mL-1 10.1016/j.ejmech.2009.07.015
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 16.0 ug.mL-1 10.1128/aac.00661-10
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 23.13 ug.mL-1 10.1021/acsmedchemlett.1c00431
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 25.0 ug.mL-1 10.1021/acsmedchemlett.1c00431
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 160.0 nM 10.1016/j.bmc.2016.09.044
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 160.0 nM 10.1016/j.bmcl.2012.12.069
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 160.0 nM 10.1016/j.bmcl.2017.05.050
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 160.0 nM 10.1016/j.ejmech.2014.08.009
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 160.0 nM 10.1016/j.ejmech.2017.11.035
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 200.0 nM 10.1016/j.bmcl.2016.03.066
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 400.0 nM 10.1016/j.bmcl.2019.02.019
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 500.0 nM 10.1016/j.ejmech.2014.05.069
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 500.0 nM 10.1016/j.ejmech.2016.11.041
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 500.0 nM 10.1128/aac.00055-06
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 700.0 nM 10.1016/j.bmcl.2019.02.019
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1000.0 nM 10.1016/j.ejmech.2016.11.041
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1600.0 nM 10.1016/j.bmcl.2019.02.019
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1700.0 nM 10.1016/j.bmcl.2019.02.019
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 2000.0 nM 10.1016/j.ejmech.2014.05.069
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 2000.0 nM 10.1016/j.ejmech.2016.11.041
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 8000.0 nM 10.1016/j.ejmech.2014.05.069
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 32000.0 nM 10.1016/j.ejmech.2014.05.069
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 32000.0 nM 10.1016/j.ejmech.2016.11.041
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC50 0.24 ug.mL-1 10.1016/j.bmcl.2022.128692
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.19 ug.mL-1 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.22 ug.mL-1 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.24 ug.mL-1 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.25 ug.mL-1 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.37 ug.mL-1 10.1016/j.bmcl.2022.128692
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.91 ug.mL-1 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 160.0 nM 10.1016/j.bmcl.2014.01.007
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 160.0 nM 10.1016/j.ejmech.2013.09.061
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 400.0 nM 10.1016/j.bmcl.2019.02.019
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 460.0 nM 10.1016/j.ejmech.2020.112821
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 1830.0 nM 10.1016/j.ejmech.2020.112821
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 0.5 uM 10.1016/j.bmc.2017.08.010
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 0.5 uM 10.1021/acs.jmedchem.5b00608
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 0.5 uM 10.1021/acs.jmedchem.9b00912
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 1.0 uM 10.1016/j.bmc.2017.08.010
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 1.0 uM 10.1021/acs.jmedchem.5b00608
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 1.0 uM 10.1021/acs.jmedchem.9b00912
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 2.0 uM 10.1016/j.bmc.2017.08.010
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 2.0 uM 10.1021/acs.jmedchem.5b00608
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 2.0 uM 10.1021/acs.jmedchem.9b00912
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 32.0 uM 10.1016/j.bmc.2017.08.010
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 32.0 uM 10.1021/acs.jmedchem.5b00608
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC>99 32.0 uM 10.1021/acs.jmedchem.9b00912
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) Polyketide synthase Pks13 MIC=<90 1.0 ug ml-1 10.1021/acs.jmedchem.9b00010
Mycobacterium tuberculosis variant bovis Mycobacterium tuberculosis variant bovis MIC 0.125 ug.mL-1 10.1128/aac.01302-08
Mycobacterium ulcerans Mycobacterium ulcerans Log10 cfu 3.92 None 10.1128/aac.00821-06
Mycobacteroides abscessus Mycobacteroides abscessus Activity nan None 10.1128/aac.00986-07
Mycobacteroides abscessus Mycobacteroides abscessus log10cfu 1.1 None 10.1128/aac.00986-07
Mycobacteroides abscessus Mycobacteroides abscessus MBC 32.0 ug ml-1 10.1128/aac.00986-07
Mycobacteroides abscessus Mycobacteroides abscessus MBC 64.0 ug ml-1 10.1128/aac.00986-07
Mycobacteroides abscessus Mycobacteroides abscessus MBC 128.0 ug ml-1 10.1128/aac.00986-07
Mycobacteroides abscessus Mycobacteroides abscessus MIC 2.0 ug.mL-1 10.1128/aac.00986-07
Mycobacteroides abscessus Mycobacteroides abscessus MIC 12.5 ug.mL-1 10.1021/acs.jmedchem.7b00582
Mycobacteroides abscessus Mycobacteroides abscessus MIC 25.0 ug.mL-1 10.1021/acs.jmedchem.7b00582
Mycobacteroides abscessus Mycobacteroides abscessus MIC 32.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides abscessus Mycobacteroides abscessus MIC 64.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides abscessus Mycobacteroides abscessus MIC 100.0 ug.mL-1 10.1021/acs.jmedchem.7b00582
Mycobacteroides abscessus Mycobacteroides abscessus MIC 128.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides abscessus Mycobacteroides abscessus MIC50 2.0 ug.mL-1 10.1128/aac.00695-08
Mycobacteroides abscessus Mycobacteroides abscessus MIC50 2.3 ug.mL-1 10.1016/j.bmcl.2022.128692
Mycobacteroides abscessus Mycobacteroides abscessus MIC50 4.3 ug.mL-1 10.1016/j.bmcl.2022.128692
Mycobacteroides abscessus Mycobacteroides abscessus MIC50 16.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides abscessus Mycobacteroides abscessus MIC50 3900.0 nM 10.1016/j.ejmech.2020.112908
Mycobacteroides abscessus Mycobacteroides abscessus MIC50 7400.0 nM 10.1016/j.ejmech.2020.112908
Mycobacteroides abscessus Mycobacteroides abscessus MIC90 3.4 ug.mL-1 10.1016/j.bmcl.2022.128692
Mycobacteroides abscessus Mycobacteroides abscessus MIC90 5.9 ug.mL-1 10.1016/j.bmcl.2022.128692
Mycobacteroides abscessus Mycobacteroides abscessus MIC90 8.0 ug.mL-1 10.1128/aac.00695-08
Mycobacteroides abscessus Mycobacteroides abscessus MIC90 32.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides chelonae Mycobacteroides chelonae MIC50 1.0 ug.mL-1 10.1128/aac.00695-08
Mycobacteroides chelonae Mycobacteroides chelonae MIC50 8.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides chelonae Mycobacteroides chelonae MIC90 8.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides chelonae Mycobacteroides chelonae MIC90 16.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium aurum Mycolicibacterium aurum MIC90 1830.0 nM 10.1016/j.ejmech.2020.112821
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC 4.0 ug.mL-1 10.1128/aac.01551-06
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC50 1.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC50 1.0 ug.mL-1 10.1128/aac.01551-06
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC90 2.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC90 4.0 ug.mL-1 10.1128/aac.01551-06
Mycolicibacterium mageritense Mycolicibacterium mageritense MIC 0.5 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium peregrinum Mycolicibacterium peregrinum MIC50 0.5 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium peregrinum Mycolicibacterium peregrinum MIC90 1.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 0.03 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 0.25 ug.mL-1 10.1016/j.bmc.2010.11.001
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 0.25 ug.mL-1 10.1016/j.bmc.2016.03.060
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 0.25 ug.mL-1 10.1021/acsmedchemlett.5b00255
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 1.25 ug.mL-1 10.1016/j.bmcl.2009.09.095
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 15600.0 nM 10.1016/j.bmc.2016.10.009
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 29000.0 nM 10.1016/j.ejmech.2021.113212
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 50000.0 nM 10.1016/j.ejmech.2021.113212
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC90 460.0 nM 10.1016/j.ejmech.2020.112821
Nocardia brasiliensis Nocardia brasiliensis MIC 0.001 ug.mL-1 10.1128/aac.01102-06
Nocardia carnea Nocardia carnea MIC 0.0005 ug.mL-1 10.1128/aac.01102-06
Nocardia cyriacigeorgica Nocardia cyriacigeorgica MIC 6e-05 ug.mL-1 10.1128/aac.01102-06
Nocardia farcinica Nocardia farcinica Activity nan None 10.1128/aac.00021-10
Nocardia farcinica Nocardia farcinica MIC 0.001 ug.mL-1 10.1128/aac.01102-06
Nocardia farcinica Nocardia farcinica MIC 1.0 ug.mL-1 10.1128/aac.00021-10
Nocardia farcinica Nocardia farcinica MIC 64.0 ug.mL-1 10.1128/aac.00021-10
Nocardia farcinica Nocardia farcinica MIC 1024.0 ug.mL-1 10.1128/aac.00021-10
Nocardia nova Nocardia nova MIC 0.00012 ug.mL-1 10.1128/aac.01102-06
Nocardia otitidiscaviarum Nocardia otitidiscaviarum MIC 0.001 ug.mL-1 10.1128/aac.01102-06
Nocardia sp. Nocardia sp. MIC 0.00025 ug.mL-1 10.1128/aac.01102-06
Nocardia transvalensis Nocardia transvalensis MIC 0.032 ug.mL-1 10.1128/aac.01102-06
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Pasteurella sp. Pasteurella sp. Activity 31.0 % 10.1128/aac.01808-09
Pluralibacter gergoviae Pluralibacter gergoviae MIC 2.0 ug.mL-1 10.1128/aac.00572-10
Proteus hauseri Proteus hauseri MIC 11950.0 nM 10.1016/j.bmc.2015.09.044
Proteus hauseri Proteus hauseri MIC 12000.0 nM 10.1016/j.ejmech.2016.04.011
Proteus mirabilis Proteus mirabilis Activity 0.0 % 10.1128/aac.00675-09
Proteus mirabilis Proteus mirabilis Activity 63.6 % 10.1128/aac.01400-07
Proteus mirabilis Proteus mirabilis Activity 92.0 % 10.1128/aac.00426-09
Proteus mirabilis Proteus mirabilis Activity 100.0 % 10.1128/aac.01400-07
Proteus mirabilis Proteus mirabilis Activity 100.0 % 10.1128/aac.01509-06
Proteus mirabilis Proteus mirabilis Activity 100.0 % 10.1128/aac.01808-09
Proteus mirabilis Proteus mirabilis MIC 0.5 ug.mL-1 10.1128/aac.01400-07
Proteus mirabilis Proteus mirabilis MIC 1.0 ug.mL-1 10.1128/aac.00336-08
Proteus mirabilis Proteus mirabilis MIC 8.0 ug.mL-1 10.1128/aac.01400-08
Proteus mirabilis Proteus mirabilis MIC50 2.0 ug.mL-1 10.1128/aac.01400-07
Proteus mirabilis Proteus mirabilis MIC50 2.0 ug.mL-1 10.1128/aac.01509-06
Proteus mirabilis Proteus mirabilis MIC50 4.0 ug.mL-1 10.1128/aac.00336-08
Proteus mirabilis Proteus mirabilis MIC50 4.0 ug.mL-1 10.1128/aac.01400-07
Proteus mirabilis Proteus mirabilis MIC50 8.0 ug.mL-1 10.1128/aac.00572-10
Proteus mirabilis Proteus mirabilis MIC90 4.0 ug.mL-1 10.1128/aac.01400-07
Proteus mirabilis Proteus mirabilis MIC90 4.0 ug.mL-1 10.1128/aac.01509-06
Proteus mirabilis Proteus mirabilis MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Proteus mirabilis Proteus mirabilis MIC90 64.0 ug.mL-1 10.1128/aac.00572-10
Proteus mirabilis Proteus mirabilis MIC90 128.0 ug.mL-1 10.1128/aac.01400-07
Proteus vulgaris Proteus vulgaris MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Proteus vulgaris Proteus vulgaris MIC 512.0 ug.mL-1 10.1016/j.bmcl.2015.11.095
Proteus vulgaris Proteus vulgaris MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Proteus vulgaris Proteus vulgaris MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Providencia rettgeri Providencia rettgeri Activity 80.0 % 10.1128/aac.01400-07
Providencia rettgeri Providencia rettgeri Activity 84.6 % 10.1128/aac.01400-07
Providencia rettgeri Providencia rettgeri MIC 0.5 ug.mL-1 10.1128/aac.01400-07
Providencia rettgeri Providencia rettgeri MIC50 1.0 ug.mL-1 10.1128/aac.01400-07
Providencia rettgeri Providencia rettgeri MIC50 2.0 ug.mL-1 10.1128/aac.01400-07
Providencia rettgeri Providencia rettgeri MIC90 32.0 ug.mL-1 10.1128/aac.01400-07
Providencia stuartii Providencia stuartii MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Providencia stuartii Providencia stuartii MIC 1.0 ug.mL-1 10.1021/jm00108a037
Providencia stuartii Providencia stuartii MIC 8.0 ug.mL-1 10.1128/aac.00572-10
Providencia stuartii Providencia stuartii MIC 16.0 ug.mL-1 10.1021/jm00108a037
Providencia stuartii Providencia stuartii MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Providencia stuartii Providencia stuartii MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 0.0 % 10.1128/aac.01538-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 1.7 % 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 3.6 deltalog10CFU 10.1021/acs.jmedchem.6b01903
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 8.0 ug ml-1 10.1128/aac.01043-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 9.0 % 10.1128/aac.00810-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 18.6 % 10.1128/aac.00453-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 18.6 % 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 19.0 % 10.1128/aac.00810-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 19.0 % 10.1128/aac.01483-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 50.0 % 10.1128/aac.00707-08
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 51.0 % 10.1128/aac.00679-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 82.0 % 10.1128/aac.00851-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 85.0 % 10.1128/aac.00426-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 85.3 % 10.1128/aac.01400-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 90.9 % 10.1128/aac.00851-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 93.3 % 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 95.6 % 10.1128/aac.00851-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 96.0 % 10.1128/aac.01808-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 100.0 % 10.1128/aac.01400-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1016/j.bmc.2016.10.009
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1016/j.bmcl.2005.02.029
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1128/aac.01278-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1128/aac.01602-08
Pseudomonas aeruginosa Pseudomonas aeruginosa AD50 nan None 10.1128/aac.01278-06
Pseudomonas aeruginosa Pseudomonas aeruginosa BBC 4.0 ug ml-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa BBC 8.0 ug ml-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa BBC 16.0 ug ml-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa BBC 64.0 ug ml-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa EC50 3.8 ug.mL-1 10.1016/j.bmc.2017.02.003
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 4.0 None 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa Inhibition nan % 10.1128/aac.01452-08
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 15.0 mm 10.1007/s00044-013-0779-x
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 16.0 mm 10.1016/j.bmc.2015.04.015
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 17.0 mm 10.1007/s00044-011-9729-7
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 17.0 mm 10.1016/j.ejmech.2020.112832
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 20.0 mm 10.1128/aac.01212-07
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 22.0 mm 10.1016/j.bmcl.2016.09.059
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 22.1 mm 10.1007/s00044-011-9708-z
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 23.0 mm 10.1016/j.ejmech.2006.12.010
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 30.0 mm 10.1016/j.ejmech.2008.07.017
Pseudomonas aeruginosa Pseudomonas aeruginosa log10CFU/g 2.0 None 10.1021/acs.jmedchem.5b00262
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 0.012 mM 10.1016/j.ejmech.2008.07.017
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 2.0 ug ml-1 10.1128/aac.01452-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 4.0 ug ml-1 10.1128/aac.01452-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 32.0 ug ml-1 10.1128/aac.01452-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 64.0 ug ml-1 10.1128/aac.01452-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC>99.9 0.125 uM 10.1021/acs.jmedchem.8b01348
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC>99.9 0.25 uM 10.1021/acs.jmedchem.8b01348
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC>99.9 64.0 uM 10.1021/acs.jmedchem.8b01348
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.06 ug.mL-1 10.1128/aac.01400-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1016/j.bmc.2010.11.001
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1021/jm800997s
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1021/jm900615h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1039/c4md00078a
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00413-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00572-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.01107-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.8 ug.mL-1 10.1021/acs.jnatprod.0c00741
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2011.08.095
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.ejmech.2016.12.008
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.5b00262
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/jm900615h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00415-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.01107-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.bmcl.2005.08.032
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.bmcl.2010.12.084
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.ejmech.2012.01.031
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1021/acs.jnatprod.9b00305
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1021/acs.jnatprod.9b01000
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1021/jm400560z
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1021/jm401148j
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1021/jm900615h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1039/C5MD00429B
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00080-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00413-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00572-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.01107-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.01360-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.01400-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.01452-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.3 ug.mL-1 10.1021/acsmedchemlett.5b00255
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.5 ug.mL-1 10.1016/j.bmcl.2017.03.075
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 3.0 ug.mL-1 10.1128/aac.00465-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 3.0 ug.mL-1 10.1128/aac.00810-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 3.0 ug.mL-1 10.1128/aac.00822-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 3.0 ug.mL-1 10.1128/aac.01034-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1016/j.ejmech.2020.112252
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b01903
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1021/jm1000437
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1021/jm401148j
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1021/jm900615h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1039/C5MD00429B
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00080-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00110-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00413-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00572-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00679-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00899-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00900-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.01107-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.01212-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.01452-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.5 ug.mL-1 10.1016/j.bmc.2017.02.003
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.0 ug.mL-1 10.1128/aac.01573-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/jm400560z
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/jm401148j
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/jm900615h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00080-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00413-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00572-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00707-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.01107-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.01212-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.01646-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.0 ug.mL-1 10.1128/aac.00822-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 14.0 ug.mL-1 10.1128/aac.00572-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.ejmech.2020.112252
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00080-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00465-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00707-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.01405-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.01452-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.01483-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.01646-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 24.0 ug.mL-1 10.1128/aac.00707-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 24.0 ug.mL-1 10.1128/aac.01573-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 31.3 ug.mL-1 10.1016/j.bmc.2016.03.060
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1021/jm00023a011
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1039/C5MD00429B
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00572-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00707-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00822-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00824-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00900-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.01011-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.01360-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.01646-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 48.0 ug.mL-1 10.1128/aac.00810-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1021/jm00023a011
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00080-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00679-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00810-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00822-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.01646-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/jm1000437
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.00110-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.00679-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.00707-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.01360-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.01646-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.00900-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.01345-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.01573-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1128/aac.01646-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6000.0 nM 10.1016/j.ejmech.2008.07.017
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 14000.0 nM 10.1021/acs.jnatprod.7b00496
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 62500.0 nM 10.1016/j.bmc.2016.10.009
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 85000.0 nM 10.1016/j.ejmech.2016.04.011
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 85380.0 nM 10.1016/j.bmc.2015.09.044
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 4.0 ug.mL-1 10.1016/j.bmcl.2008.04.023
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 4.0 ug.mL-1 10.1021/jm2014748
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 4.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 4.0 ug.mL-1 10.1128/aac.01400-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 8.0 ug.mL-1 10.1021/jm400560z
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 8.0 ug.mL-1 10.1128/aac.00336-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 8.0 ug.mL-1 10.1128/aac.01400-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 16.0 ug.mL-1 10.1021/acs.jmedchem.7b00377
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 16.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 16.0 ug.mL-1 10.1128/aac.00572-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 64.0 ug.mL-1 10.1021/jm400560z
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC80 8.0 ug.mL-1 10.1016/j.bmcl.2008.04.023
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC>90 1.8 ug ml-1 10.1021/np400145u
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 16.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 16.0 ug.mL-1 10.1128/aac.01400-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 32.0 ug.mL-1 10.1016/j.bmcl.2008.04.023
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 32.0 ug.mL-1 10.1021/jm2014748
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 32.0 ug.mL-1 10.1128/aac.01400-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 64.0 ug.mL-1 10.1021/jm400560z
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 64.0 ug.mL-1 10.1128/aac.00572-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 128.0 ug.mL-1 10.1021/acs.jmedchem.7b00377
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 128.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 3660.0 nM 10.1016/j.ejmech.2020.112821
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC>95 0.0625 uM 10.1021/acs.jmedchem.8b01348
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC>95 0.125 uM 10.1021/acs.jmedchem.8b01348
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC>95 0.25 uM 10.1021/acs.jmedchem.8b01348
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC>95 64.0 uM 10.1021/acs.jmedchem.8b01348
Pseudomonas aeruginosa Pseudomonas aeruginosa Ratio 13.0 None 10.1128/aac.01468-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Ratio 20.0 None 10.1128/aac.01468-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Aminoglycoside 3'-phosphotransferase type IIb Kcat/Km 400000.0 /M/s 10.1128/aac.01034-06
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Aminoglycoside 3'-phosphotransferase type IIb Km 440000.0 nM 10.1128/aac.01034-06
Pseudomonas fluorescens Pseudomonas fluorescens Activity 31.0 % 10.1128/aac.01808-09
Pseudomonas fluorescens Pseudomonas fluorescens MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Pseudomonas fluorescens Pseudomonas fluorescens MIC 0.9 ug.mL-1 10.1016/j.bmcl.2014.12.021
Pseudomonas fluorescens Pseudomonas fluorescens MIC 0.9 ug.mL-1 10.1016/j.ejmech.2010.07.038
Pseudomonas fluorescens Pseudomonas fluorescens MIC50 16.0 ug.mL-1 10.1128/aac.00336-08
Pseudomonas fluorescens Pseudomonas fluorescens MIC90 128.0 ug.mL-1 10.1128/aac.00336-08
Pseudomonas putida Pseudomonas putida MIC 1.0 ug.mL-1 10.1128/aac.00707-08
Pseudomonas putida Pseudomonas putida MIC 1.0 ug.mL-1 10.1128/aac.00931-08
Pseudomonas putida Pseudomonas putida MIC 32.0 ug.mL-1 10.1128/aac.00838-06
Pseudomonas sp. Pseudomonas sp. Activity 7.7 % 10.1128/aac.01400-07
Pseudomonas sp. Pseudomonas sp. Activity 90.9 % 10.1128/aac.01400-07
Pseudomonas sp. Pseudomonas sp. MIC 0.5 ug.mL-1 10.1128/aac.01400-07
Pseudomonas sp. Pseudomonas sp. MIC 2.0 ug.mL-1 10.1128/aac.01400-07
Pseudomonas sp. Pseudomonas sp. MIC50 4.0 ug.mL-1 10.1128/aac.01400-07
Pseudomonas sp. Pseudomonas sp. MIC50 128.0 ug.mL-1 10.1128/aac.01400-07
Pseudomonas sp. Pseudomonas sp. MIC90 16.0 ug.mL-1 10.1128/aac.01400-07
Pseudomonas sp. Pseudomonas sp. MIC90 128.0 ug.mL-1 10.1128/aac.01400-07
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1a adrenergic receptor Ki nan None None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1b adrenergic receptor Ki nan None None
Rattus norvegicus Androgen Receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus Cyclooxygenase-1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Peripheral myelin protein 22 Potency 9074.3 nM None
Rattus norvegicus Rattus norvegicus ALB 34400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 35600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 36000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 36300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 36400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 36600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 37100.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 39000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 39700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 41300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 41700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 128.89 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 186.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 187.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 190.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 209.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 228.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 233.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 308.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 351.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 364.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 370.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 382.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 25.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 28.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 29.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 30.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 30.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 31.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 50.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 51.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 52.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 53.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 59.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 72.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 78.2 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 79.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 80.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 81.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 82.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 82.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 82.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 84.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 84.7 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 329.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.032 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.042 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.091 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.097 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.12 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.13 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.38 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.52 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.72 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.77 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.88 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 112.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 130.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 140.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 142.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 143.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 144.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 146.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 151.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 160.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 170.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 173.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 177.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 98.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 99.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 99.6 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 100.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 105.4 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 105.6 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 107.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 107.2 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 107.8 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 449.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 570.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 621.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 624.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 636.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 692.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 708.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 743.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 758.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 773.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 803.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 813.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 151.2 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 231.2 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 233.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 235.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 292.2 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 303.2 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 316.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 320.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 334.3 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 385.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 388.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 419.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 32330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 32670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 34500000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 35000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 35670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 5.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 5.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 6.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 6.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.076 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.087 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.11 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.12 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.14 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 29.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.84 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.86 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.88 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.92 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 1.28 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1198.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1244.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1254.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1362.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1366.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1456.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1472.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1491.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1550.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1606.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1626.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1783.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.87 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 34.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 34.43 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 35.97 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 44.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 45.32 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 45.74 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 45.98 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 47.53 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 47.66 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 126300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 128800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 130000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 131300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 132200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 137000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 138600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 147200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 148800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 154600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 156500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 78.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 98.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 105.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 105.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 106.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 109.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 111.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 112.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 113.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 123.1 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 129.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 142.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 17.1 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 22.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 23.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 24.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 32.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 6.63 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 7.26 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 9.1 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 9.91 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 10.45 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 13.53 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 3175.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 6237.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 6333.5 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 7637.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 8480.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 10165.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 80.34 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 81.3 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 81.34 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 83.34 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 83.57 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 86.2 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 86.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 88.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 89.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 90.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 90.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 91.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 18.0 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 18.72 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 19.07 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 19.4 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 19.76 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 20.02 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.0 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.03 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.6 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.95 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.38 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.93 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 302200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 321600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 324400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 328800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 329300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 332400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 377700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 381000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 382300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 383000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 387000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 388000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 56.35 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 57.9 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 59.02 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 59.4 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 60.1 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.0 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.38 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.7 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.93 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.6 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.95 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.2 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.13 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.14 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.18 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.21 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.29 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.4 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 11.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 19.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 38.83 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 67.83 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 121.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 225.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.62 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.64 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.68 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.76 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.26 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.46 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 9.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 9.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 10.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 10.4 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 12.66 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 12.97 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 13.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 14.14 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 14.9 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 15.14 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 0.83 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1.17 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1.34 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1.56 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1.84 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 2.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 480.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 661.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 661.17 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 743.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 950.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 993.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 99.4 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 100.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 100.4 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 102.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 103.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 105.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 107.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 108.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 111.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 112.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 114.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 117.4 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 622330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 865000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 903330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 924330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1125330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1177670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1322400.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1323800.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1365600.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1439300.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1445500.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1513400.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.04 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.37 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.46 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.47 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.52 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.62 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.93 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.07 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.34 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.57 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.81 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 53000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 58300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 59700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 59800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 60300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 64800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 66600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5270000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5380000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5440000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5480000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5640000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5810000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7450000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7680000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7720000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7740000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7950000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 8210000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.17 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.33 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.37 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.97 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 144.2 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 144.47 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 144.64 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 147.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 149.2 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 149.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 150.6 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 152.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 5.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 5.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 6.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 6.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 7.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 8.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 9.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 9.4 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 10.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 11.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 12.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 14.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 3670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 7000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 7030.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 8110.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 8360.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 8370.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 9700.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 10860.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 11270.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 11910.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 12880.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 16610.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 nan None None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki nan None None
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Salmonella Salmonella MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Salmonella Salmonella MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Salmonella Salmonella MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Salmonella enterica Salmonella enterica MIC 7.8 ug.mL-1 10.1016/j.bmc.2016.03.060
Salmonella enterica Salmonella enterica MIC 13660.0 nM 10.1016/j.bmc.2015.09.044
Salmonella enterica subsp. enterica serovar Enteritidis Salmonella enteritidis MIC 14000.0 nM 10.1016/j.ejmech.2016.04.011
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium IZ 19.0 mm 10.1016/j.ejmech.2011.02.039
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MBC>99.9 0.125 uM 10.1021/acs.jmedchem.8b01348
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 12.0 ug.mL-1 10.1016/j.ejmech.2011.02.039
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC>95 0.0625 uM 10.1021/acs.jmedchem.8b01348
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC>95 0.125 uM 10.1021/acs.jmedchem.8b01348
Serratia liquefaciens Serratia liquefaciens MIC 4.0 ug.mL-1 10.1128/aac.00572-10
Serratia marcescens Serratia marcescens Activity 30.0 % 10.1128/aac.01400-07
Serratia marcescens Serratia marcescens Activity 96.3 % 10.1128/aac.01400-07
Serratia marcescens Serratia marcescens Activity 100.0 % 10.1128/aac.01808-09
Serratia marcescens Serratia marcescens MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Serratia marcescens Serratia marcescens MIC 0.5 ug.mL-1 10.1128/aac.01400-07
Serratia marcescens Serratia marcescens MIC 1.0 ug.mL-1 10.1021/jm00108a037
Serratia marcescens Serratia marcescens MIC 2.0 ug.mL-1 10.1021/jm00108a037
Serratia marcescens Serratia marcescens MIC 2.0 ug.mL-1 10.1128/aac.00572-10
Serratia marcescens Serratia marcescens MIC 8.0 ug.mL-1 10.1021/jm00108a037
Serratia marcescens Serratia marcescens MIC 8.0 ug.mL-1 10.1128/aac.00572-10
Serratia marcescens Serratia marcescens MIC 16.0 ug.mL-1 10.1021/jm00023a011
Serratia marcescens Serratia marcescens MIC 30.0 ug.mL-1 10.1128/aac.00572-10
Serratia marcescens Serratia marcescens MIC 64.0 ug.mL-1 10.1021/jm00023a011
Serratia marcescens Serratia marcescens MIC 128.0 ug.mL-1 10.1021/jm00023a011
Serratia marcescens Serratia marcescens MIC50 1.0 ug.mL-1 10.1128/aac.01400-07
Serratia marcescens Serratia marcescens MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Serratia marcescens Serratia marcescens MIC50 128.0 ug.mL-1 10.1128/aac.01400-07
Serratia marcescens Serratia marcescens MIC90 2.0 ug.mL-1 10.1128/aac.01400-07
Serratia marcescens Serratia marcescens MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Serratia marcescens Serratia marcescens MIC90 128.0 ug.mL-1 10.1128/aac.01400-07
Serratia sp. Serratia sp. MIC50 8.0 ug.mL-1 10.1128/aac.00572-10
Staphylococcus aureus Staphylococcus aureus Activity 50.0 % 10.1021/acs.jmedchem.8b01433
Staphylococcus aureus Staphylococcus aureus Activity 80.6 % 10.1128/aac.01400-07
Staphylococcus aureus Staphylococcus aureus Activity 100.0 % 10.1128/aac.01400-07
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1016/j.bmc.2016.03.060
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1016/j.bmc.2016.10.009
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/jm0703183
Staphylococcus aureus Staphylococcus aureus DIZ nan None 10.1016/j.ejmech.2011.02.039
Staphylococcus aureus Staphylococcus aureus IZ 16.0 mm 10.1016/j.bmc.2015.04.015
Staphylococcus aureus Staphylococcus aureus IZ 17.0 mm 10.1007/s00044-013-0779-x
Staphylococcus aureus Staphylococcus aureus IZ 17.0 mm 10.1016/j.bmcl.2011.04.117
Staphylococcus aureus Staphylococcus aureus IZ 17.0 mm 10.1016/j.ejmech.2011.02.039
Staphylococcus aureus Staphylococcus aureus IZ 18.0 mm 10.1007/s00044-011-9729-7
Staphylococcus aureus Staphylococcus aureus IZ 19.0 mm 10.1016/j.ejmech.2011.02.039
Staphylococcus aureus Staphylococcus aureus IZ 20.0 mm 10.1007/s00044-013-0779-x
Staphylococcus aureus Staphylococcus aureus IZ 20.0 mm 10.1016/j.ejmech.2011.02.039
Staphylococcus aureus Staphylococcus aureus IZ 20.0 mm 10.1016/j.ejmech.2020.112832
Staphylococcus aureus Staphylococcus aureus IZ 23.0 mm 10.1016/j.bmcl.2016.09.059
Staphylococcus aureus Staphylococcus aureus IZ 25.0 mm 10.1016/j.ejmech.2008.07.017
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1128/aac.01400-07
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmc.2016.03.060
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmc.2010.11.001
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmc.2016.03.060
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2010.12.084
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2016.12.008
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/acs.jnatprod.0c00741
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/acsmedchemlett.5b00255
Staphylococcus aureus Staphylococcus aureus MIC 0.9 ug.mL-1 10.1016/j.bmcl.2014.12.021
Staphylococcus aureus Staphylococcus aureus MIC 0.9 ug.mL-1 10.1016/j.ejmech.2010.07.038
Staphylococcus aureus Staphylococcus aureus MIC 0.9 ug.mL-1 10.1016/j.ejmech.2014.10.023
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2010.09.084
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1021/acsmedchemlett.5b00255
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1021/jm00108a037
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1039/c4md00078a
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.01400-07
Staphylococcus aureus Staphylococcus aureus MIC 1.6 ug.mL-1 10.1128/aac.01682-09
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmc.2016.03.060
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2010.09.084
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2009.12.016
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2012.01.031
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1039/C5MD00429B
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.00572-10
Staphylococcus aureus Staphylococcus aureus MIC 2.5 ug.mL-1 10.1016/j.bmcl.2017.03.075
Staphylococcus aureus Staphylococcus aureus MIC 3.2 ug.mL-1 10.1128/aac.01682-09
Staphylococcus aureus Staphylococcus aureus MIC 3.9 ug.mL-1 10.1016/j.bmc.2016.03.060
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2010.12.084
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/jm00023a011
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/jm1000437
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/ml200202y
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.00572-10
Staphylococcus aureus Staphylococcus aureus MIC 7.8 ug.mL-1 10.1016/j.bmc.2016.03.060
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.bmcl.2010.09.084
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1021/jm1000437
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1021/jm800997s
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1021/ml200202y
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1039/c4md00078a
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1039/C5MD00429B
Staphylococcus aureus Staphylococcus aureus MIC 13.0 ug.mL-1 10.1128/aac.00572-10
Staphylococcus aureus Staphylococcus aureus MIC 15.6 ug.mL-1 10.1016/j.bmc.2016.03.060
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.bmc.2010.11.001
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.bmcl.2005.08.032
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.bmcl.2010.09.084
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.bmcl.2011.08.095
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.ejmech.2009.03.006
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.ejmech.2016.12.008
Staphylococcus aureus Staphylococcus aureus MIC 18.0 ug.mL-1 10.1128/aac.00572-10
Staphylococcus aureus Staphylococcus aureus MIC 25.0 ug.mL-1 10.1128/aac.01682-09
Staphylococcus aureus Staphylococcus aureus MIC 31.3 ug.mL-1 10.1016/j.bmc.2016.03.060
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1021/acsmedchemlett.5b00255
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1021/jm00023a011
Staphylococcus aureus Staphylococcus aureus MIC 50.0 ug.mL-1 10.1016/j.ejmech.2011.02.039
Staphylococcus aureus Staphylococcus aureus MIC 62.5 ug.mL-1 10.1016/j.bmc.2016.03.060
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/ml200202y
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1039/C5MD00429B
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.00572-10
Staphylococcus aureus Staphylococcus aureus MIC 100.0 ug.mL-1 10.1016/j.bmcl.2009.09.095
Staphylococcus aureus Staphylococcus aureus MIC 100.0 ug.mL-1 10.1016/j.ejmech.2011.02.039
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1016/j.bmcl.2010.12.084
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1016/j.bmcl.2015.11.095
Staphylococcus aureus Staphylococcus aureus MIC 3400.0 nM 10.1016/j.ejmech.2021.113212
Staphylococcus aureus Staphylococcus aureus MIC 5000.0 nM 10.1016/j.ejmech.2021.113212
Staphylococcus aureus Staphylococcus aureus MIC 18780.0 nM 10.1016/j.bmc.2015.09.044
Staphylococcus aureus Staphylococcus aureus MIC 19000.0 nM 10.1016/j.ejmech.2016.04.011
Staphylococcus aureus Staphylococcus aureus MIC 31300.0 nM 10.1016/j.bmc.2016.10.009
Staphylococcus aureus Staphylococcus aureus MIC nan ug.mL-1 10.1021/jm00108a037
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1021/acs.jnatprod.7b00496
Staphylococcus aureus Staphylococcus aureus MIC50 1.0 ug.mL-1 10.1128/aac.00248-09
Staphylococcus aureus Staphylococcus aureus MIC50 1.0 ug.mL-1 10.1128/aac.01400-07
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1128/aac.00248-09
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1128/aac.01400-07
Staphylococcus aureus Staphylococcus aureus MIC50 27.32 mmol/ml 10.1016/j.ejmech.2010.02.023
Staphylococcus aureus Staphylococcus aureus MIC50 32.0 ug.mL-1 10.1021/ml200202y
Staphylococcus aureus Staphylococcus aureus MIC90 2.0 ug.mL-1 10.1128/aac.01400-07
Staphylococcus aureus Staphylococcus aureus MIC90 4.0 ug.mL-1 10.1128/aac.00248-09
Staphylococcus aureus Staphylococcus aureus MIC90 16.0 ug.mL-1 10.1128/aac.00248-09
Staphylococcus aureus Staphylococcus aureus MIC90 64.0 ug.mL-1 10.1021/ml200202y
Staphylococcus aureus Staphylococcus aureus MIC90 128.0 ug.mL-1 10.1128/aac.01400-07
Staphylococcus aureus Staphylococcus aureus MIC90 nan None 10.1016/j.ejmech.2020.112821
Staphylococcus capitis Staphylococcus capitis MIC 0.5 ug.mL-1 10.1016/j.bmcl.2010.09.084
Staphylococcus epidermidis Staphylococcus epidermidis Activity 73.1 % 10.1128/aac.01400-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 98.8 % 10.1128/aac.01400-07
Staphylococcus epidermidis Staphylococcus epidermidis IZ 22.0 mm 10.1016/j.ejmech.2011.02.039
Staphylococcus epidermidis Staphylococcus epidermidis IZ 24.0 mm 10.1007/s00044-013-0779-x
Staphylococcus epidermidis Staphylococcus epidermidis IZ 25.0 mm 10.1007/s00044-013-0779-x
Staphylococcus epidermidis Staphylococcus epidermidis IZ 33.0 mm 10.1016/j.ejmech.2008.07.017
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.03 ug.mL-1 10.1128/aac.01400-07
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.5 ug.mL-1 10.1016/j.ejmech.2009.12.016
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.8 ug.mL-1 10.1016/j.bmcl.2010.09.084
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1.0 ug.mL-1 10.1021/jm1000437
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1021/jm1000437
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1128/aac.01400-07
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.5 ug.mL-1 10.1016/j.bmcl.2017.03.075
Staphylococcus epidermidis Staphylococcus epidermidis MIC 4.0 ug.mL-1 10.1016/j.bmcl.2010.09.084
Staphylococcus epidermidis Staphylococcus epidermidis MIC 4.0 ug.mL-1 10.1128/aac.00572-10
Staphylococcus epidermidis Staphylococcus epidermidis MIC 8.0 ug.mL-1 10.1016/j.bmcl.2010.09.084
Staphylococcus epidermidis Staphylococcus epidermidis MIC 12.0 ug.mL-1 10.1016/j.ejmech.2011.02.039
Staphylococcus epidermidis Staphylococcus epidermidis MIC 13.0 ug.mL-1 10.1128/aac.00572-10
Staphylococcus epidermidis Staphylococcus epidermidis MIC 15.6 ug.mL-1 10.1016/j.bmc.2016.03.060
Staphylococcus epidermidis Staphylococcus epidermidis MIC 18.0 ug.mL-1 10.1128/aac.00572-10
Staphylococcus epidermidis Staphylococcus epidermidis MIC 31.3 ug.mL-1 10.1016/j.bmc.2016.03.060
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 0.5 ug.mL-1 10.1128/aac.01400-07
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 4.0 ug.mL-1 10.1128/aac.01400-07
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 2.0 ug.mL-1 10.1128/aac.01400-07
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 64.0 ug.mL-1 10.1128/aac.01400-07
Staphylococcus sp. Staphylococcus sp. MIC50 16.0 ug.mL-1 10.1128/aac.00572-10
Staphylococcus sp. Staphylococcus sp. MIC90 64.0 ug.mL-1 10.1128/aac.00572-10
Staphylococcus warneri Staphylococcus warneri MIC 0.25 ug.mL-1 10.1016/j.bmcl.2010.09.084
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 31.0 % 10.1128/aac.01808-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 0.5 ug.mL-1 10.1128/aac.00336-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 64.0 ug.mL-1 10.1128/aac.00795-06
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 512.0 ug.mL-1 10.1021/jm1000437
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 16.0 ug.mL-1 10.1128/aac.00336-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 128.0 ug.mL-1 10.1128/aac.00248-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 128.0 ug.mL-1 10.1128/aac.00248-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 128.0 ug.mL-1 10.1128/aac.00336-08
Streptococcus equinus Streptococcus equinus MIC 64.0 ug.mL-1 10.1128/aac.00603-06
Streptococcus pasteurianus Streptococcus pasteurianus MIC 32.0 ug.mL-1 10.1128/aac.00603-06
Streptococcus pasteurianus Streptococcus pasteurianus MIC 64.0 ug.mL-1 10.1128/aac.00603-06
Streptococcus pasteurianus Streptococcus pasteurianus MIC 128.0 ug.mL-1 10.1128/aac.00603-06
Streptococcus pasteurianus Streptococcus pasteurianus MIC 512.0 ug.mL-1 10.1128/aac.00603-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1021/jm1000437
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1021/jm1000437
Streptococcus pyogenes Streptococcus pyogenes IZ 20.0 mm 10.1007/s00044-011-9729-7
Sus scrofa LLC-PK1 Activity nan None 10.1128/aac.01680-07
Trypanosoma brucei 6-phospho-1-fructokinase Potency 39810.7 nM None
None ADMET Activity nan None 10.1021/jm201082a
None ADMET C50 0.081 uM 10.1021/jm00385a015
None ADMET C50 0.21 uM 10.1021/jm00385a015
None ADMET CL 1.1 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET Cmax 853.81 nM 10.1128/aac.01099-07
None ADMET Cmax 1844.23 nM 10.1128/aac.01099-07
None ADMET Kill at C50 68.0 % 10.1021/jm00385a015
None ADMET Kill at C50 76.0 % 10.1021/jm00385a015
None ADMET LD90 0.14 uM 10.1021/jm00385a015
None ADMET LD90 0.32 uM 10.1021/jm00385a015
None ADMET MRT 2.4 hr 10.1124/dmd.108.020479
None ADMET T1/2 0.58 hr 10.1128/aac.01125-08
None ADMET T1/2 2.4 hr 10.1124/dmd.108.020479
None ADMET Uptake at C50 4.7 None 10.1021/jm00385a015
None ADMET Uptake at C50 6.4 None 10.1021/jm00385a015
None ADMET Vdss 0.16 L.kg-1 10.1124/dmd.108.020479
None BMDM CC50 90.0 ug.mL-1 10.1016/j.bmcl.2022.128692
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None NON-PROTEIN TARGET Activity 59.0 % 10.1128/aac.01173-09
None NON-PROTEIN TARGET Fu 0.88 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 0.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 6.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 15.3 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET MIC 6e-05 ug.mL-1 10.1128/aac.01102-06
None NON-PROTEIN TARGET MIC 0.00025 ug.mL-1 10.1128/aac.01102-06
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 0.78 ug.mL-1 10.1016/j.bmcl.2009.09.095
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.00899-09
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1128/aac.00899-09
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.00656-09
None NON-PROTEIN TARGET MIC 3900.0 nM 10.1016/j.bmc.2016.10.009
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC50 8.0 ug.mL-1 10.1128/aac.00572-10
None NON-PROTEIN TARGET MIC50 8.0 ug.mL-1 10.1128/aac.00858-06
None NON-PROTEIN TARGET MIC50 16.0 ug.mL-1 10.1128/aac.00858-06
None NON-PROTEIN TARGET MIC50 128.0 ug.mL-1 10.1128/aac.00248-09
None NON-PROTEIN TARGET MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC90 64.0 ug.mL-1 10.1128/aac.00858-06
None NON-PROTEIN TARGET MIC90 128.0 ug.mL-1 10.1128/aac.00248-09
None Nucleic Acid Frel 0.29 None 10.1016/j.bmcl.2005.02.007
None Nucleic Acid Kd 50.0 nM 10.1021/jm9000659
None Nucleic Acid Kd 100000.0 nM 10.1016/j.bmcl.2011.12.103
None Phospholipidosis Maximum test concentration that did not exhibit cytotoxicity 25.0 uM None
None Phospholipidosis Phospholipidosis nan None 10.1021/ci6004542
None Phospholipidosis Phospholipidosis nan None 10.1021/mp100103e
None Phospholipidosis Phospholipidosis nan None 10.1080/15376510701857262
None Phospholipidosis Phospholipidosis as % of positive control 4.9 % None
None Ribosomal RNA A-site IC50 70.0 nM 10.1021/acs.jmedchem.6b00793
None Unchecked Denaturation rate constant 0.093 min-1 10.1016/s0960-894x(03)00085-4
None Unchecked Hepatotoxicity (acute) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 160.0 nM 10.1016/s0960-894x(03)00085-4
None Unchecked IC50 1020.0 nM 10.1016/s0960-894x(03)00085-4
None Unchecked IC50 64630.0 nM 10.1021/acs.jmedchem.6b00793
None Unchecked IC50 nan None 10.1021/acs.jmedchem.5b01620
None Unchecked IC50 nan None None
None Unchecked Inhibition 0.0 % 10.1016/j.bmcl.2004.04.055
None Unchecked Inhibition 43.0 % 10.1016/s0960-894x(03)00085-4
None Unchecked Inhibition 85.0 % 10.1016/s0960-894x(03)00085-4
None Unchecked Kcat 1.38 /s 10.1021/jm800997s
None Unchecked Kcat 8.3 /s 10.1128/aac.01444-09
None Unchecked Kcat 13.8 /s 10.1128/aac.01444-09
None Unchecked Kcat 22.3 /s 10.1128/aac.01444-09
None Unchecked Kcat/Km 1.0 10'6/M/s 10.1128/aac.01444-09
None Unchecked Kcat/Km 1.3 10'5/M/s 10.1128/aac.01444-09
None Unchecked Kcat/Km 2.4 10'4/M/s 10.1021/jm800997s
None Unchecked Kcat/Km 9.4 10'5/M/s 10.1128/aac.01444-09
None Unchecked Ki nan None None
None Unchecked Km 13500.0 nM 10.1128/aac.01444-09
None Unchecked Km 23700.0 nM 10.1128/aac.01444-09
None Unchecked Km 57400.0 nM 10.1021/jm800997s
None Unchecked Km 62900.0 nM 10.1128/aac.01444-09
None Unchecked MBC>99.9 0.0625 uM 10.1021/acs.jmedchem.8b01348
None Unchecked MIC 0.4 ug.mL-1 10.1021/acs.jnatprod.0c00741
None Unchecked MIC 12.5 ug.mL-1 10.1021/acs.jmedchem.7b00582
None Unchecked MIC 12.8 ug.mL-1 10.1021/acs.jmedchem.7b00582
None Unchecked MIC 25.0 ug.mL-1 10.1021/acs.jmedchem.7b00582
None Unchecked MIC 50.0 ug.mL-1 10.1021/acs.jmedchem.7b00582
None Unchecked MIC 100.0 ug.mL-1 10.1021/acs.jmedchem.7b00582
None Unchecked MIC50 nan None 10.1016/j.ejmech.2020.112908
None Unchecked MIC>95 0.0625 uM 10.1021/acs.jmedchem.8b01348
None Unchecked Ratio 0.125 None 10.1128/aac.00413-08
None Unchecked Ratio 0.5 None 10.1128/aac.00413-08
None Unchecked Ratio 1.0 None 10.1128/aac.00413-08
None Unchecked Ratio 2.0 None 10.1128/aac.00413-08
None Unchecked Ratio IC50 923.29 None 10.1021/acs.jmedchem.6b00793
None Unchecked Vmax 2.75 umol/min/mg 10.1021/jm800997s

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT004406 CC(=O)[32S].NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O>>CC(=O)NC1C(O)C(CO)O[C@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](N)C[C@H]2NC(=O)[C@@H](O)CCN)C1O None
AKRT004407 CC(=O)[32S].NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O>>CC(=O)NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](NC(=O)[C@@H](O)CCN)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O None
AKRT004644 CC(=O)[CoA].NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O>>CC(=O)NC1C(O)C(CO)O[C@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](N)C[C@H]2NC(=O)[C@@H](O)CCN)C1O enzymemap_32182
AKRT004645 CC(=O)[CoA].NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O>>CC(=O)NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](NC(=O)[C@@H](O)CCN)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O enzymemap_32244
AKRT007185 CCC(=O)[CoA].NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O>>CCC(=O)N[C@H]1[C@H](O)[C@@H](CO)O[C@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](N)C[C@H]2NC(=O)[C@@H](O)CCN)[C@@H]1O enzymemap_32195
AKRT016480 N=c1[nH]c(=O)c2ncn([C@@H]3O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O)c2[nH]1.NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O>>N=c1[nH]c(=O)c2ncn([C@@H]3O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O)c2[nH]1.NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1OP(=O)(O)O None
AKRT017775 NCC(=O)[CoA].NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O>>NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](NC(=O)CN)[C@H]1O enzymemap_32186
AKRT018351 NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O.Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1>>NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1OP(=O)(O)O.Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1 None
AKRT018352 NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O>>NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1OP(=O)(O)O RXN-16735
AKRT022708 O=C(O)CC(=O)[CoA].NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O>>NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](NC(=O)CC(=O)O)[C@H]1O enzymemap_32191