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3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

AlkaPlorer ID: AK005832

Synonym: None

IUPAC Name: (6R,7S)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Structure

SMILES: CO[C@@]1(N=C(O)CC2=CC=CS2)C(=O)N2C(C(=O)O)=C(COC(=N)O)CS[C@@H]21

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InChI: InChI=1S/C16H17N3O7S2/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22)/t14-,16+/m1/s1

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InChIKey: WZOZEZRFJCJXNZ-ZBFHGGJFSA-N

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Reference

PubChem CID: 441199

CAS: 33564-30-6

NPASS: NPC487968

Source

Species Genus Family Order Class Phylum Kingdom Domain

Properties Information

Molecule Weight: 427.46000000000015

TPSA？: 152.74

MolLogP？: 1.3529700000000005

Number of H-Donors: 4

Number of H-Acceptors: 8

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.00072-09
Acinetobacter baumannii Acinetobacter baumannii MIC 12.0 ug.mL-1 10.1128/aac.00072-09
Acinetobacter baumannii Acinetobacter baumannii MIC 192.0 ug.mL-1 10.1128/aac.00072-09
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00072-08
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00267-07
Acinetobacter baumannii Acinetobacter baumannii MIC 20000.0 nM 10.6019/CHEMBL4513161
Acinetobacter baumannii ADC-11 Kcat 1.5 /s 10.1128/aac.00050-10
Acinetobacter baumannii ADC-11 Kcat/Km 3.0 /uM/s 10.1128/aac.00050-10
Acinetobacter baumannii ADC-11 Ki 500.0 nM 10.1128/aac.00050-10
Acinetobacter baumannii Beta-lactamase ADC-33 Kcat 0.3 /s 10.1128/aac.00050-10
Acinetobacter baumannii Beta-lactamase ADC-33 Kcat/Km 3.0 /uM/s 10.1128/aac.00050-10
Acinetobacter baumannii Beta-lactamase ADC-33 Ki 100.0 nM 10.1128/aac.00050-10
Acinetobacter genomosp. 3 ADC-14 protein Kcat 0.02 /s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-14 protein Kcat/Km 941.18 /mM/s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-14 protein Km 20.0 nM 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-16 protein Kcat 0.33 /s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-16 protein Kcat/Km 1875.71 /mM/s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-16 protein Km 180.0 nM 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-18 protein Kcat 0.27 /s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-18 protein Kcat/Km 1992.54 /mM/s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-18 protein Km 130.0 nM 10.1128/aac.00485-08
Acinetobacter haemolyticus Acinetobacter haemolyticus MIC 32.0 ug.mL-1 10.1128/aac.00267-07
Acinetobacter lwoffii Acinetobacter lwoffii MIC nan None 10.1128/aac.00598-10
Acinetobacter pittii Acinetobacter pittii MIC 48.0 ug.mL-1 10.1128/aac.00485-08
Acinetobacter pittii Acinetobacter pittii MIC 64.0 ug.mL-1 10.1128/aac.00485-08
Acinetobacter pittii Acinetobacter pittii MIC 128.0 ug.mL-1 10.1128/aac.00485-08
Acinetobacter pittii Acinetobacter pittii MIC 192.0 ug.mL-1 10.1128/aac.00485-08
Acinetobacter pittii Acinetobacter pittii MIC 256.0 ug.mL-1 10.1128/aac.00072-08
Acinetobacter pittii Acinetobacter pittii MIC 256.0 ug.mL-1 10.1128/aac.00485-08
Acinetobacter radioresistens Acinetobacter radioresistens MIC 8.0 ug.mL-1 10.1128/aac.00999-08
Acinetobacter sp. Acinetobacter sp. Activity nan None 10.1128/aac.01808-09
Actinomyces israelii Actinomyces israelii Activity 0.0 % 10.1128/aac.00481-10
Actinomyces israelii Actinomyces israelii Activity 92.0 % 10.1128/aac.00481-10
Actinomyces israelii Actinomyces israelii MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Actinomyces israelii Actinomyces israelii MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Actinomyces israelii Actinomyces israelii MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Actinomyces naeslundii Actinomyces naeslundii Activity 0.0 % 10.1128/aac.00481-10
Actinomyces naeslundii Actinomyces naeslundii Activity 92.0 % 10.1128/aac.00481-10
Actinomyces naeslundii Actinomyces naeslundii MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Actinomyces naeslundii Actinomyces naeslundii MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Actinomyces naeslundii Actinomyces naeslundii MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Aeromonas allosaccharophila Extended-spectrum beta-lactamase PER-6 Kcat nan None 10.1128/aac.01585-09
Aeromonas allosaccharophila Extended-spectrum beta-lactamase PER-6 Kcat/Km nan None 10.1128/aac.01585-09
Aeromonas allosaccharophila Extended-spectrum beta-lactamase PER-6 Km nan None 10.1128/aac.01585-09
Aeromonas caviae Aeromonas caviae MIC 512.0 ug.mL-1 10.1128/aac.01462-06
Aeromonas caviae IMP-19 Kcat 9.7 /s 10.1128/aac.01462-06
Aeromonas caviae IMP-19 Kcat/Km 0.29 None 10.1128/aac.01462-06
Aeromonas caviae IMP-19 Km 33000.0 nM 10.1128/aac.01462-06
Aeromonas sp. Aeromonas sp. MIC 2.0 ug.mL-1 10.1128/aac.00770-08
Anaerococcus prevotii Anaerococcus prevotii Activity 0.0 % 10.1128/aac.00481-10
Anaerococcus prevotii Anaerococcus prevotii Activity 0.0 % 10.1128/aac.00696-08
Anaerococcus prevotii Anaerococcus prevotii Activity 100.0 % 10.1128/aac.00481-10
Anaerococcus prevotii Anaerococcus prevotii MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Anaerococcus prevotii Anaerococcus prevotii MIC 1.0 ug.mL-1 10.1021/jm00068a009
Anaerococcus prevotii Anaerococcus prevotii MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Anaerococcus prevotii Anaerococcus prevotii MIC50 0.5 ug.mL-1 10.1128/aac.00481-10
Anaerococcus prevotii Anaerococcus prevotii MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
Anaerococcus prevotii Anaerococcus prevotii MIC90 1.0 ug.mL-1 10.1128/aac.00481-10
Anaerococcus prevotii Anaerococcus prevotii MIC90 4.0 ug.mL-1 10.1128/aac.00696-08
Bacillus clausii Beta-lactamase Activity 500.0 U 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Activity nan None 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Kcat 0.01 /s 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Kcat/Km nan None 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Km 10.0 nM 10.1128/aac.00537-07
Bacteroides caccae Bacteroides caccae Activity 6.3 % 10.1128/aac.00696-08
Bacteroides caccae Bacteroides caccae Activity 7.0 % 10.1128/aac.00481-10
Bacteroides caccae Bacteroides caccae Activity 8.9 % 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae Activity 10.9 % 10.1128/aac.01435-06
Bacteroides caccae Bacteroides caccae Activity 25.0 % 10.1128/aac.00481-10
Bacteroides caccae Bacteroides caccae MIC 0.06 ug.mL-1 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae MIC 4.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides caccae Bacteroides caccae MIC 4.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides caccae Bacteroides caccae MIC 17.61 ug.mL-1 10.1128/aac.01435-06
Bacteroides caccae Bacteroides caccae MIC50 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae MIC50 16.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides caccae Bacteroides caccae MIC50 32.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides caccae Bacteroides caccae MIC90 32.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae MIC90 32.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides caccae Bacteroides caccae MIC90 32.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides caccae Bacteroides caccae MIC90 64.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides fragilis Bacteroides fragilis Activity 3.0 % 10.1128/aac.00696-08
Bacteroides fragilis Bacteroides fragilis Activity 5.0 % 10.1128/aac.00481-10
Bacteroides fragilis Bacteroides fragilis Activity 5.2 % 10.1128/aac.01435-06
Bacteroides fragilis Bacteroides fragilis Activity 6.4 % 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis Activity 79.0 % 10.1128/aac.00481-10
Bacteroides fragilis Bacteroides fragilis MIC 0.06 ug.mL-1 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis MIC 1.0 ug.mL-1 10.1128/aac.00336-08
Bacteroides fragilis Bacteroides fragilis MIC 2.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides fragilis Bacteroides fragilis MIC 4.0 ug.mL-1 10.1021/jm00068a009
Bacteroides fragilis Bacteroides fragilis MIC 4.0 ug.mL-1 10.1128/aac.01047-08
Bacteroides fragilis Bacteroides fragilis MIC 8.0 ug.mL-1 10.1021/jm00068a009
Bacteroides fragilis Bacteroides fragilis MIC 8.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides fragilis Bacteroides fragilis MIC 15.42 ug.mL-1 10.1128/aac.01435-06
Bacteroides fragilis Bacteroides fragilis MIC50 8.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis MIC50 8.0 ug.mL-1 10.1128/aac.01047-08
Bacteroides fragilis Bacteroides fragilis MIC50 16.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides fragilis Bacteroides fragilis MIC50 16.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides fragilis Bacteroides fragilis MIC90 16.0 ug.mL-1 10.1128/aac.01047-08
Bacteroides fragilis Bacteroides fragilis MIC90 32.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis MIC90 32.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides fragilis Bacteroides fragilis MIC90 32.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides fragilis Bacteroides fragilis MIC90 32.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides ovatus Bacteroides ovatus Activity 7.0 % 10.1128/aac.00481-10
Bacteroides ovatus Bacteroides ovatus Activity 12.2 % 10.1128/aac.00081-08
Bacteroides ovatus Bacteroides ovatus Activity 14.3 % 10.1128/aac.00696-08
Bacteroides ovatus Bacteroides ovatus Activity 17.2 % 10.1128/aac.01435-06
Bacteroides ovatus Bacteroides ovatus Activity 25.0 % 10.1128/aac.00481-10
Bacteroides ovatus Bacteroides ovatus MIC 0.5 ug.mL-1 10.1128/aac.00081-08
Bacteroides ovatus Bacteroides ovatus MIC 4.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides ovatus Bacteroides ovatus MIC 8.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides ovatus Bacteroides ovatus MIC 27.16 ug.mL-1 10.1128/aac.01435-06
Bacteroides ovatus Bacteroides ovatus MIC50 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides ovatus Bacteroides ovatus MIC50 16.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides ovatus Bacteroides ovatus MIC50 32.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides ovatus Bacteroides ovatus MIC90 32.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides ovatus Bacteroides ovatus MIC90 64.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides ovatus Bacteroides ovatus MIC90 64.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides ovatus Bacteroides ovatus MIC90 64.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides sp. Bacteroides sp. Activity 23.9 % 10.1128/aac.00081-08
Bacteroides sp. Bacteroides sp. MIC 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides sp. Bacteroides sp. MIC50 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides sp. Bacteroides sp. MIC90 64.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris Activity 10.9 % 10.1128/aac.01435-06
Bacteroides stercoris Bacteroides stercoris Activity 23.9 % 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris MIC 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris MIC 17.61 ug.mL-1 10.1128/aac.01435-06
Bacteroides stercoris Bacteroides stercoris MIC50 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris MIC90 64.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris MIC90 64.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 7.0 % 10.1128/aac.00481-10
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 10.3 % 10.1128/aac.00696-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 16.8 % 10.1128/aac.01435-06
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 23.6 % 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 25.0 % 10.1128/aac.00481-10
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 0.06 ug.mL-1 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 2.0 ug.mL-1 10.1021/jm00068a009
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 4.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 4.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 16.0 ug.mL-1 10.1128/aac.01047-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 29.5 ug.mL-1 10.1128/aac.01435-06
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 16.0 ug.mL-1 10.1128/aac.01047-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 32.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 32.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 32.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 32.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 64.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 64.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 64.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides uniformis Bacteroides uniformis Activity 7.5 % 10.1128/aac.01435-06
Bacteroides uniformis Bacteroides uniformis Activity 9.4 % 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis Activity 9.5 % 10.1128/aac.00696-08
Bacteroides uniformis Bacteroides uniformis MIC 0.06 ug.mL-1 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis MIC 2.0 ug.mL-1 10.1128/aac.01047-08
Bacteroides uniformis Bacteroides uniformis MIC 4.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides uniformis Bacteroides uniformis MIC 12.91 ug.mL-1 10.1128/aac.01435-06
Bacteroides uniformis Bacteroides uniformis MIC50 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis MIC50 16.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides uniformis Bacteroides uniformis MIC50 16.0 ug.mL-1 10.1128/aac.01047-08
Bacteroides uniformis Bacteroides uniformis MIC90 16.0 ug.mL-1 10.1128/aac.01047-08
Bacteroides uniformis Bacteroides uniformis MIC90 32.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis MIC90 32.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides uniformis Bacteroides uniformis MIC90 64.0 ug.mL-1 10.1128/aac.00696-08
Bos taurus Monoamine oxidase A Activity nan None 10.1021/jm800656v
Burkholderia cenocepacia Burkholderia cenocepacia MIC 512.0 ug.mL-1 10.1128/aac.00946-08
Burkholderia cenocepacia PenB class A beta-lactamase Kcat nan None 10.1128/aac.00946-08
Burkholderia cenocepacia PenB class A beta-lactamase Kcat/Km nan None 10.1128/aac.00946-08
Burkholderia cenocepacia PenB class A beta-lactamase Km nan None 10.1128/aac.00946-08
Campylobacter coli Campylobacter coli MIC 64.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC50 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC90 256.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 2.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 32.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 64.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 256.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 512.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC50 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC90 256.0 ug.mL-1 10.1128/aac.01655-08
Candida albicans Candida albicans IZ 0.0 mm 10.1021/np900382x
Candida albicans Candida albicans MIC 20000.0 nM 10.6019/CHEMBL4513161
Chryseobacterium indologenes Chryseobacterium indologenes MIC 16.0 ug.mL-1 10.1128/aac.01607-08
Citrobacter freundii Citrobacter freundii Activity 16.0 % 10.1128/aac.00426-09
Citrobacter freundii Citrobacter freundii Activity 17.0 % 10.1128/aac.01808-09
Citrobacter freundii Citrobacter freundii MIC 1.0 ug.mL-1 10.1128/aac.01395-06
Citrobacter freundii Citrobacter freundii MIC 2.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 8.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 64.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 128.0 ug.mL-1 10.1128/aac.01312-09
Citrobacter freundii Citrobacter freundii MIC 256.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Citrobacter freundii Citrobacter freundii MIC 512.0 ug.mL-1 10.1128/aac.01337-07
Citrobacter freundii PER-2 beta-lactamase Activity 18.0 % 10.1128/aac.01395-06
Citrobacter freundii PER-2 beta-lactamase Kcat 0.001 /s 10.1128/aac.01395-06
Citrobacter freundii PER-2 beta-lactamase Ki 140.0 nM 10.1128/aac.01395-06
Citrobacter gillenii Gil1 Kcat nan None 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Kcat/Km nan None 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Km nan None 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Ratio nan None 10.1128/aac.01152-06
Clostridioides difficile Clostridioides difficile Activity 0.0 % 10.1128/aac.00481-10
Clostridioides difficile Clostridioides difficile Activity 100.0 % 10.1128/aac.00481-10
Clostridioides difficile Clostridioides difficile Activity nan None 10.1128/aac.00696-08
Clostridioides difficile Clostridioides difficile MIC 8.0 ug.mL-1 10.1128/aac.00696-08
Clostridioides difficile Clostridioides difficile MIC 32.0 ug.mL-1 10.1021/jm00068a009
Clostridioides difficile Clostridioides difficile MIC 64.0 ug.mL-1 10.1128/aac.00481-10
Clostridioides difficile Clostridioides difficile MIC50 64.0 ug.mL-1 10.1128/aac.00481-10
Clostridioides difficile Clostridioides difficile MIC90 128.0 ug.mL-1 10.1128/aac.00481-10
[Clostridium] innocuum [Clostridium] innocuum Activity 55.6 % 10.1128/aac.00696-08
[Clostridium] innocuum [Clostridium] innocuum MIC 1.0 ug.mL-1 10.1128/aac.00696-08
[Clostridium] innocuum [Clostridium] innocuum MIC50 64.0 ug.mL-1 10.1128/aac.00696-08
[Clostridium] innocuum [Clostridium] innocuum MIC90 128.0 ug.mL-1 10.1128/aac.00696-08
Clostridium paraputrificum Clostridium paraputrificum Activity 55.6 % 10.1128/aac.00696-08
Clostridium paraputrificum Clostridium paraputrificum MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Clostridium paraputrificum Clostridium paraputrificum MIC50 64.0 ug.mL-1 10.1128/aac.00696-08
Clostridium paraputrificum Clostridium paraputrificum MIC90 128.0 ug.mL-1 10.1128/aac.00696-08
Clostridium perfringens Clostridium perfringens Activity 0.0 % 10.1128/aac.00481-10
Clostridium perfringens Clostridium perfringens Activity 0.0 % 10.1128/aac.00696-08
Clostridium perfringens Clostridium perfringens Activity 100.0 % 10.1128/aac.00481-10
Clostridium perfringens Clostridium perfringens MIC 0.5 ug.mL-1 10.1128/aac.00481-10
Clostridium perfringens Clostridium perfringens MIC 0.5 ug.mL-1 10.1128/aac.01047-08
Clostridium perfringens Clostridium perfringens MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Clostridium perfringens Clostridium perfringens MIC 2.0 ug.mL-1 10.1021/jm00068a009
Clostridium perfringens Clostridium perfringens MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
Clostridium perfringens Clostridium perfringens MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
Clostridium perfringens Clostridium perfringens MIC50 1.0 ug.mL-1 10.1128/aac.01047-08
Clostridium perfringens Clostridium perfringens MIC90 2.0 ug.mL-1 10.1128/aac.00481-10
Clostridium perfringens Clostridium perfringens MIC90 2.0 ug.mL-1 10.1128/aac.01047-08
Clostridium perfringens Clostridium perfringens MIC90 4.0 ug.mL-1 10.1128/aac.00696-08
Clostridium septicum Clostridium septicum MIC 4.0 ug.mL-1 10.1021/jm00068a009
Clostridium tertium Clostridium tertium Activity 55.6 % 10.1128/aac.00696-08
Clostridium tertium Clostridium tertium MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Clostridium tertium Clostridium tertium MIC50 64.0 ug.mL-1 10.1128/aac.00696-08
Clostridium tertium Clostridium tertium MIC90 128.0 ug.mL-1 10.1128/aac.00696-08
Cryptococcus neoformans Cryptococcus neoformans MIC 20000.0 nM 10.6019/CHEMBL4513161
Cutibacterium acnes Cutibacterium acnes Activity 0.0 % 10.1128/aac.00696-08
Cutibacterium acnes Cutibacterium acnes MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Cutibacterium acnes Cutibacterium acnes MIC 2.0 ug.mL-1 10.1021/jm00068a009
Cutibacterium acnes Cutibacterium acnes MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
Cutibacterium acnes Cutibacterium acnes MIC90 1.0 ug.mL-1 10.1128/aac.00696-08
Dialister invisus Dialister invisus Activity 8.0 ug ml-1 10.1128/aac.00538-07
Dialister invisus Dialister invisus Activity 16.0 ug ml-1 10.1128/aac.00538-07
Dialister invisus Dialister invisus MIC 0.5 ug.mL-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus Activity 8.0 ug ml-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus Activity 16.0 ug ml-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus MIC 0.5 ug.mL-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus MIC50 0.5 ug.mL-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus MIC90 0.5 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes Activity 8.0 ug ml-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes Activity 16.0 ug ml-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC 0.5 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC50 0.5 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC90 1.0 ug.mL-1 10.1128/aac.00538-07
Dialister propionicifaciens Dialister propionicifaciens Activity 8.0 ug ml-1 10.1128/aac.00538-07
Dialister propionicifaciens Dialister propionicifaciens Activity 16.0 ug ml-1 10.1128/aac.00538-07
Dialister propionicifaciens Dialister propionicifaciens MIC 0.5 ug.mL-1 10.1128/aac.00538-07
Edwardsiella ictaluri Edwardsiella ictaluri MIC 32.0 ug.mL-1 10.1128/aac.01312-08
Eggerthella lenta Eggerthella lenta Activity 0.0 % 10.1128/aac.00481-10
Eggerthella lenta Eggerthella lenta Activity 92.0 % 10.1128/aac.00481-10
Eggerthella lenta Eggerthella lenta MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Eggerthella lenta Eggerthella lenta MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Eggerthella lenta Eggerthella lenta MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Eikenella corrodens Eikenella corrodens MIC 4.0 ug.mL-1 10.1021/jm00068a009
Elizabethkingia meningoseptica GOB-1 metallo-beta-lactamase Kcat/Km 2.5 10'5/M/s 10.1128/aac.01062-07
Enterobacter Enterobacter MIC 4.0 ug.mL-1 10.1128/aac.01614-06
Enterobacter Enterobacter MIC 8.0 ug.mL-1 10.1128/aac.01614-06
Enterobacter Enterobacter MIC 100.0 ug.mL-1 10.1021/jm00214a018
Enterobacter Enterobacter Relative potency 0.03 None 10.1016/S0960-894X(01)80923-9
Enterobacter cloacae Enterobacter cloacae Activity 1.0 % 10.1128/aac.01808-09
Enterobacter cloacae Enterobacter cloacae Activity 7.0 % 10.1128/aac.00426-09
Enterobacter cloacae Enterobacter cloacae MIC 2.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 4.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.00931-08
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00260-09
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.01082-06
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Enterobacter cloacae Enterobacter cloacae MIC 512.0 ug.mL-1 10.1128/aac.00033-09
Enterobacter cloacae Enterobacter cloacae MIC 512.0 ug.mL-1 10.1128/aac.01312-09
Enterobacter cloacae Enterobacter cloacae MIC 512.0 ug.mL-1 10.1128/aac.01431-06
Enterobacter cloacae IMI-1 Kcat 0.3 /s 10.1128/aac.00491-07
Enterobacter cloacae IMI-1 Kcat/Km 6.7 /mM/s 10.1128/aac.00491-07
Enterobacter cloacae IMI-1 Km 45000.0 nM 10.1128/aac.00491-07
Enterobacteriaceae Enterobacteriaceae Activity 16.6 % 10.1128/aac.00044-07
Enterobacteriaceae Enterobacteriaceae Activity 40.0 % 10.1128/aac.00044-07
Enterobacteriaceae Enterobacteriaceae MIC 0.78 ug.mL-1 10.1021/jm00214a018
Enterobacteriaceae Enterobacteriaceae MIC 100.0 ug.mL-1 10.1021/jm00214a018
Enterococcus Enterococcus MIC 100.0 ug.mL-1 10.1021/jm00214a018
Enterococcus Enterococcus Relative potency 0.06 None 10.1016/S0960-894X(01)80923-9
Enterococcus faecium Enterococcus faecium IZ nan None 10.1021/np900382x
Escherichia coli Beta-lactamase ACC-4 Kcat 0.01 /s 10.1128/aac.00389-07
Escherichia coli Beta-lactamase ACC-4 Kcat/Km nan None 10.1128/aac.00389-07
Escherichia coli Beta-lactamase ACC-4 Km nan None 10.1128/aac.00389-07
Escherichia coli Beta-lactamase SHV-11 Kcat 0.01 /s 10.1128/aac.00387-08
Escherichia coli Beta-lactamase SHV-11 Kcat/Km nan None 10.1128/aac.00387-08
Escherichia coli Beta-lactamase SHV-11 Km nan None 10.1128/aac.00387-08
Escherichia coli BlaVIM-1 Kcat 25.0 /s 10.1128/aac.00458-09
Escherichia coli BlaVIM-1 Kcat 26.0 /s 10.1128/aac.00017-09
Escherichia coli BlaVIM-1 Kcat/Km 0.2 /s/microM 10.1128/aac.00017-09
Escherichia coli BlaVIM-1 Kcat/Km 0.2 /uM/s 10.1128/aac.00458-09
Escherichia coli BlaVIM-1 Km 130000.0 nM 10.1128/aac.00458-09
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 1.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity 5.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity 6.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 10.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 11.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity 16.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 16.7 % 10.1128/aac.01176-07
Escherichia coli Escherichia coli Activity 19.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 20.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 21.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 40.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 43.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 54.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 61.1 % 10.1128/aac.01176-07
Escherichia coli Escherichia coli Activity 66.0 % 10.1128/aac.00426-09
Escherichia coli Escherichia coli Activity 67.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 68.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 71.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity 71.1 % 10.1128/aac.01509-06
Escherichia coli Escherichia coli Activity 74.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 80.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 89.0 % 10.1128/aac.00426-09
Escherichia coli Escherichia coli Activity 93.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity 94.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 94.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity 100.0 % 10.1128/aac.01176-07
Escherichia coli Escherichia coli Activity 100.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity 120.0 % 10.1128/aac.01420-09
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00614-07
Escherichia coli Escherichia coli IZ 8.8 mm 10.1074/jbc.m700084200
Escherichia coli Escherichia coli IZ 9.3 mm 10.1074/jbc.m700084200
Escherichia coli Escherichia coli IZ 10.8 mm 10.1074/jbc.m700084200
Escherichia coli Escherichia coli IZ 10.9 mm 10.1074/jbc.m700084200
Escherichia coli Escherichia coli IZ 16.0 mm 10.1021/np990134u
Escherichia coli Escherichia coli IZ 18.0 mm 10.1021/np900382x
Escherichia coli Escherichia coli IZ 22.0 mm 10.1021/np900382x
Escherichia coli Escherichia coli IZ 26.0 mm 10.1021/np900382x
Escherichia coli Escherichia coli MIC 0.063 ug.mL-1 10.1128/aac.01395-06
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01395-06
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00614-07
Escherichia coli Escherichia coli MIC 0.75 ug.mL-1 10.1128/aac.00787-09
Escherichia coli Escherichia coli MIC 0.92 ug.mL-1 10.1128/aac.00787-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00098-10
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00787-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00909-06
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00961-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01585-09
Escherichia coli Escherichia coli MIC 1.5 ug.mL-1 10.1128/aac.00787-09
Escherichia coli Escherichia coli MIC 1.56 ug.mL-1 10.1021/jm00214a018
Escherichia coli Escherichia coli MIC 1.7 ug.mL-1 10.1128/aac.00787-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/jm00068a009
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00098-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00111-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00137-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00219-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00485-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00543-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00608-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00770-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00774-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00791-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00830-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00859-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01152-06
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01180-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01439-06
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01462-06
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01473-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01581-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01585-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01607-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01615-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01672-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1128/aac.00485-08
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1128/aac.00787-09
Escherichia coli Escherichia coli MIC 3.2 ug.mL-1 10.1128/aac.01420-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1016/j.ejmech.2012.03.008
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00033-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00111-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00167-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00310-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00427-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00458-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00614-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00734-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00736-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00768-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00774-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00787-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00830-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00841-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00858-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00878-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00896-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00961-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01011-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01025-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01058-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01062-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01082-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01180-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01252-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01312-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01381-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01400-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01420-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01456-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01463-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01561-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01581-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01600-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01672-07
Escherichia coli Escherichia coli MIC 4.5 ug.mL-1 10.1021/acs.jmedchem.7b00204
Escherichia coli Escherichia coli MIC 4.7 ug.mL-1 10.1128/aac.00787-09
Escherichia coli Escherichia coli MIC 6.0 ug.mL-1 10.1128/aac.00072-09
Escherichia coli Escherichia coli MIC 6.0 ug.mL-1 10.1128/aac.00133-09
Escherichia coli Escherichia coli MIC 6.0 ug.mL-1 10.1128/aac.00547-09
Escherichia coli Escherichia coli MIC 6.0 ug.mL-1 10.1128/aac.00787-09
Escherichia coli Escherichia coli MIC 7.3 ug.mL-1 10.1128/aac.00787-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00279-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00310-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00547-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00734-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00736-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00780-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00830-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00946-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01011-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01058-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01062-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01336-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01337-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01381-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01439-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01539-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01561-09
Escherichia coli Escherichia coli MIC 10.6 ug.mL-1 10.1128/aac.01420-09
Escherichia coli Escherichia coli MIC 12.0 ug.mL-1 10.1128/aac.00547-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00310-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00485-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00734-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01058-06
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01353-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01539-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01607-08
Escherichia coli Escherichia coli MIC 24.0 ug.mL-1 10.1128/aac.00133-09
Escherichia coli Escherichia coli MIC 24.0 ug.mL-1 10.1128/aac.00485-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00133-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00485-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00608-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00734-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00780-06
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00841-06
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01025-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01312-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01539-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 48.0 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01025-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01586-08
Escherichia coli Escherichia coli MIC 96.0 ug.mL-1 10.1128/aac.00072-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00033-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00111-10
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00137-10
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00608-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00841-06
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01252-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01336-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01586-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00072-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00133-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00167-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00458-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00774-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00780-06
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00858-10
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00878-10
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01011-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01462-06
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01586-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 500.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00219-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00458-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00878-10
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01337-07
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01456-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01462-06
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 2000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 5000.0 nM 10.6019/CHEMBL4513161
Escherichia coli Escherichia coli MIC 8000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 16000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 50000.0 nM 10.1016/j.ejmech.2022.114333
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.00787-09
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.00822-08
Escherichia coli Escherichia coli MIC50 2.0 ug.mL-1 10.1128/aac.01509-06
Escherichia coli Escherichia coli MIC50 4.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC50 8.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli MIC50 256.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli MIC90 8.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC90 16.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli MIC90 64.0 ug.mL-1 10.1128/aac.01509-06
Escherichia coli Escherichia coli MIC90 256.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli Ratio 2.0 None 10.1128/aac.00734-08
Escherichia coli Escherichia coli Ratio 3.3 None 10.1128/aac.01420-09
Escherichia coli Escherichia coli Ratio 4.0 None 10.1016/j.ejmech.2012.03.008
Escherichia coli Escherichia coli Ratio 4.0 None 10.1128/aac.00734-08
Escherichia coli Escherichia coli Ratio 6.0 None 10.1128/aac.01011-08
Escherichia coli Escherichia coli Relative potency 0.1 None 10.1016/S0960-894X(01)80923-9
Escherichia coli Escherichia coli Susceptibility nan None 10.1021/jm049652e
Escherichia coli Metallo-beta-lactamase Kcat 2.8 /s 10.1128/aac.00017-09
Escherichia coli Metallo-beta-lactamase Kcat 15.0 /s 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase Kcat/Km 0.12 /s/microM 10.1128/aac.00017-09
Escherichia coli Metallo-beta-lactamase Kcat/Km 1.2 uM/hr 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase Km 13000.0 nM 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase VIM-19 Kcat 30.0 /s 10.1128/aac.00458-09
Escherichia coli Metallo-beta-lactamase VIM-19 Kcat/Km 0.5 /uM/s 10.1128/aac.00458-09
Escherichia coli Metallo-beta-lactamase VIM-19 Km 60000.0 nM 10.1128/aac.00458-09
Eubacterium sp. Eubacterium sp. Activity 0.0 % 10.1128/aac.00481-10
Eubacterium sp. Eubacterium sp. Activity 92.0 % 10.1128/aac.00481-10
Eubacterium sp. Eubacterium sp. MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Eubacterium sp. Eubacterium sp. MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Eubacterium sp. Eubacterium sp. MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna Activity 0.0 % 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna Activity 0.0 % 10.1128/aac.00696-08
Finegoldia magna Finegoldia magna Activity 100.0 % 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Finegoldia magna Finegoldia magna MIC50 0.5 ug.mL-1 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
Finegoldia magna Finegoldia magna MIC90 1.0 ug.mL-1 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna MIC90 1.0 ug.mL-1 10.1128/aac.00696-08
Fluoribacter gormanii FEZ-1 protein Kcat/Km 2.7 10'5/M/s 10.1128/aac.01062-07
Fusobacterium mortiferum Fusobacterium mortiferum MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Fusobacterium necrophorum Fusobacterium necrophorum MIC 0.5 ug.mL-1 10.1021/jm00068a009
Fusobacterium nucleatum Fusobacterium nucleatum MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Fusobacterium varium Fusobacterium varium MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Haemophilus influenzae Haemophilus influenzae MIC 2.0 ug.mL-1 10.1021/jm00068a009
Homo sapiens Adenosine A1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Canalicular multispecific organic anion transporter 1 Inhibition nan % 10.1124/dmd.111.041731
Homo sapiens Canalicular multispecific organic anion transporter 2 Inhibition nan % 10.1124/dmd.111.041731
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin B receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Endothelin receptor ET-A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HEK293 CC50 20000.0 nM 10.6019/CHEMBL4513161
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 3.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Kappa opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Motilin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Multidrug resistance-associated protein 4 Inhibition nan % 10.1124/dmd.111.041731
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Oligopeptide transporter small intestine isoform Ki 10000000.0 nM 10.1021/jm048982w
Homo sapiens Peroxisome proliferator-activated receptor gamma AC50 10999.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Peroxisome proliferator-activated receptor gamma AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Pregnane X receptor AC50 2400.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Pregnane X receptor AC50 6400.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Solute carrier family 22 member 8 Inhibition nan % 10.1124/dmd.112.049569
Homo sapiens Type-1 angiotensin II receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 18837.5 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 26608.6 nM None
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Hoylesella oralis Hoylesella oralis Activity 0.0 % 10.1128/aac.00481-10
Hoylesella oralis Hoylesella oralis Activity 89.0 % 10.1128/aac.00481-10
Hoylesella oralis Hoylesella oralis MIC 0.5 ug.mL-1 10.1128/aac.00481-10
Hoylesella oralis Hoylesella oralis MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
Hoylesella oralis Hoylesella oralis MIC90 32.0 ug.mL-1 10.1128/aac.00481-10
Klebsiella Klebsiella MIC 3.12 ug.mL-1 10.1021/jm00214a018
Klebsiella Klebsiella Relative potency 0.04 None 10.1016/S0960-894X(01)80923-9
Klebsiella aerogenes Klebsiella aerogenes Activity 8.0 % 10.1128/aac.01808-09
Klebsiella aerogenes Klebsiella aerogenes Activity 22.0 % 10.1128/aac.00426-09
Klebsiella aerogenes Klebsiella aerogenes Lysis diameter 6.0 mm 10.1021/jm049652e
Klebsiella aerogenes Klebsiella aerogenes Lysis diameter 7.0 mm 10.1021/jm049652e
Klebsiella aerogenes Klebsiella aerogenes Lysis diameter 12.0 mm 10.1021/jm049652e
Klebsiella aerogenes Klebsiella aerogenes Lysis diameter 16.0 mm 10.1021/jm049652e
Klebsiella aerogenes Klebsiella aerogenes MIC 8.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella aerogenes Klebsiella aerogenes MIC 32.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella aerogenes Klebsiella aerogenes MIC 128.0 ug.mL-1 10.1021/jm00068a009
Klebsiella aerogenes Klebsiella aerogenes MIC 128.0 ug.mL-1 10.1128/aac.00822-08
Klebsiella aerogenes Klebsiella aerogenes MIC 128.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella aerogenes Klebsiella aerogenes MIC 256.0 ug.mL-1 10.1128/aac.00822-08
Klebsiella aerogenes Klebsiella aerogenes MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella aerogenes Klebsiella aerogenes MIC 512.0 ug.mL-1 10.1128/aac.00822-08
Klebsiella aerogenes Klebsiella aerogenes MIC 512.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella aerogenes Klebsiella aerogenes MIC 1024.0 ug.mL-1 10.1128/aac.00822-08
Klebsiella aerogenes Klebsiella aerogenes MIC nan None 10.1128/aac.00822-08
Klebsiella oxytoca Klebsiella oxytoca Activity 64.0 % 10.1128/aac.00426-09
Klebsiella oxytoca Klebsiella oxytoca Activity 96.0 % 10.1128/aac.01808-09
Klebsiella oxytoca Klebsiella oxytoca Activity 97.0 % 10.1128/aac.00426-09
Klebsiella oxytoca Klebsiella oxytoca MIC 3.0 ug.mL-1 10.1128/aac.01473-08
Klebsiella oxytoca Klebsiella oxytoca MIC 8.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella oxytoca Klebsiella oxytoca MIC 256.0 ug.mL-1 10.1128/aac.00260-09
Klebsiella oxytoca Klebsiella oxytoca MIC 256.0 ug.mL-1 10.1128/aac.01473-08
Klebsiella pneumoniae Beta-lactamase NDM-1 Kcat 1.0 /s 10.1128/aac.00774-09
Klebsiella pneumoniae Beta-lactamase NDM-1 Kcat/Km 0.02 /s/microM 10.1128/aac.00774-09
Klebsiella pneumoniae Beta-lactamase NDM-1 Km 49000.0 nM 10.1128/aac.00774-09
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Kcat 0.26 /s 10.1128/aac.00491-07
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Kcat/Km 2.0 /mM/s 10.1128/aac.00491-07
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Km 120000.0 nM 10.1128/aac.00491-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity 61.0 % 10.1128/aac.00426-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 66.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 74.1 % 10.1128/aac.01509-06
Klebsiella pneumoniae Klebsiella pneumoniae Activity 84.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 87.0 % 10.1128/aac.00426-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 87.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 95.0 % 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 102.0 % 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1016/j.bmcl.2015.03.057
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1021/jm00068a009
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.5 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.03.057
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00543-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01312-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01607-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 3.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 3.0 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00715-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01381-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01473-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01607-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.0 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00715-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00822-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01312-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01539-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01607-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00736-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00822-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00841-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00909-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01607-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01672-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 24.0 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00260-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00715-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00736-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00822-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00841-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01451-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01607-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01672-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 48.0 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00260-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00461-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00736-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00822-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01180-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 96.0 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00017-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00260-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00543-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00841-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.01312-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00137-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00167-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00260-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00736-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00774-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01284-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01473-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01539-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1128/aac.00017-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1128/aac.00458-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 20000.0 nM 10.6019/CHEMBL4513161
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01509-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 3.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 12.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 16.0 ug.mL-1 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 24.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 48.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.01509-06
Klebsiella pneumoniae Metallo-beta-lactamase VIM-2 Kcat 3.0 /s 10.1128/aac.00774-09
Klebsiella pneumoniae Metallo-beta-lactamase VIM-2 Kcat/Km 0.12 /s/microM 10.1128/aac.00774-09
Klebsiella pneumoniae Metallo-beta-lactamase VIM-2 Km 24000.0 nM 10.1128/aac.00774-09
Mammaliicoccus lentus Mammaliicoccus lentus MIC 2.0 ug.mL-1 10.1128/aac.00356-10
Morganella morganii Morganella morganii MIC 6.25 ug.mL-1 10.1021/jm00214a018
Morganella morganii Morganella morganii MIC 128.0 ug.mL-1 10.1128/aac.01431-06
Mus musculus Solute carrier family 22 member 6 Inhibition nan % 10.1124/dmd.112.049569
Mus musculus Solute carrier family 22 member 8 Drug uptake nan None 10.1124/dmd.112.049569
Mus musculus Solute carrier family 22 member 8 IC50 57000.0 nM 10.1124/dmd.112.049569
Mus musculus Solute carrier family 22 member 8 Inhibition nan % 10.1124/dmd.112.049569
Mycobacteroides abscessus Mycobacteroides abscessus Activity nan None 10.1128/aac.00986-07
Mycobacteroides abscessus Mycobacteroides abscessus MIC 8.0 ug.mL-1 10.1128/aac.00986-07
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC 6.25 ug.mL-1 10.1128/aac.00986-07
Mycolicibacterium mageritense Mycolicibacterium mageritense MIC 1.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 1.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 2.0 ug.mL-1 10.1016/j.ejmech.2016.12.060
Parabacteroides distasonis Parabacteroides distasonis Activity 6.7 % 10.1128/aac.00696-08
Parabacteroides distasonis Parabacteroides distasonis Activity 7.0 % 10.1128/aac.00481-10
Parabacteroides distasonis Parabacteroides distasonis Activity 25.0 % 10.1128/aac.00481-10
Parabacteroides distasonis Parabacteroides distasonis Activity 25.6 % 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis Activity 29.9 % 10.1128/aac.01435-06
Parabacteroides distasonis Parabacteroides distasonis MIC 0.06 ug.mL-1 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis MIC 4.0 ug.mL-1 10.1128/aac.00481-10
Parabacteroides distasonis Parabacteroides distasonis MIC 4.0 ug.mL-1 10.1128/aac.00696-08
Parabacteroides distasonis Parabacteroides distasonis MIC 34.18 ug.mL-1 10.1128/aac.01435-06
Parabacteroides distasonis Parabacteroides distasonis MIC50 16.0 ug.mL-1 10.1128/aac.00696-08
Parabacteroides distasonis Parabacteroides distasonis MIC50 32.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis MIC50 32.0 ug.mL-1 10.1128/aac.00481-10
Parabacteroides distasonis Parabacteroides distasonis MIC90 32.0 ug.mL-1 10.1128/aac.00481-10
Parabacteroides distasonis Parabacteroides distasonis MIC90 32.0 ug.mL-1 10.1128/aac.00696-08
Parabacteroides distasonis Parabacteroides distasonis MIC90 64.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis MIC90 128.0 ug.mL-1 10.1128/aac.01435-06
Parabacteroides merdae Parabacteroides merdae Activity 0.0 % 10.1128/aac.00696-08
Parabacteroides merdae Parabacteroides merdae Activity 10.9 % 10.1128/aac.01435-06
Parabacteroides merdae Parabacteroides merdae Activity 23.9 % 10.1128/aac.00081-08
Parabacteroides merdae Parabacteroides merdae MIC 2.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides merdae Parabacteroides merdae MIC 8.0 ug.mL-1 10.1128/aac.00696-08
Parabacteroides merdae Parabacteroides merdae MIC 17.61 ug.mL-1 10.1128/aac.01435-06
Parabacteroides merdae Parabacteroides merdae MIC50 16.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides merdae Parabacteroides merdae MIC50 16.0 ug.mL-1 10.1128/aac.00696-08
Parabacteroides merdae Parabacteroides merdae MIC90 32.0 ug.mL-1 10.1128/aac.00696-08
Parabacteroides merdae Parabacteroides merdae MIC90 64.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides merdae Parabacteroides merdae MIC90 64.0 ug.mL-1 10.1128/aac.01435-06
Parvimonas micra Parvimonas micra Activity 0.0 % 10.1128/aac.00481-10
Parvimonas micra Parvimonas micra Activity 0.0 % 10.1128/aac.00696-08
Parvimonas micra Parvimonas micra MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Parvimonas micra Parvimonas micra MIC 0.25 ug.mL-1 10.1128/aac.00481-10
Parvimonas micra Parvimonas micra MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Parvimonas micra Parvimonas micra MIC50 0.5 ug.mL-1 10.1128/aac.01047-08
Parvimonas micra Parvimonas micra MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
Parvimonas micra Parvimonas micra MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
Parvimonas micra Parvimonas micra MIC90 0.5 ug.mL-1 10.1128/aac.01047-08
Parvimonas micra Parvimonas micra MIC90 4.0 ug.mL-1 10.1128/aac.00696-08
Parvimonas micra Parvimonas micra MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Pasteurella sp. Pasteurella sp. Activity nan None 10.1128/aac.01808-09
Pectobacterium atrosepticum Pectobacterium atrosepticum MIC 8.0 ug.mL-1 10.1128/aac.01062-07
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity 0.0 % 10.1128/aac.00481-10
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity 0.0 % 10.1128/aac.00696-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity 100.0 % 10.1128/aac.00481-10
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 0.06 ug.mL-1 10.1128/aac.00481-10
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 0.5 ug.mL-1 10.1128/aac.00481-10
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 4.0 ug.mL-1 10.1128/aac.00696-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius Activity 100.0 % 10.1128/aac.00481-10
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 0.12 ug.mL-1 10.1128/aac.01047-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 0.25 ug.mL-1 10.1128/aac.00481-10
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 2.0 ug.mL-1 10.1021/jm00068a009
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 0.25 ug.mL-1 10.1128/aac.01047-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 0.38 ug.mL-1 10.1128/aac.00056-07
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 0.75 ug.mL-1 10.1128/aac.00056-07
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 1.0 ug.mL-1 10.1128/aac.01047-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Peptostreptococcus sp. Peptostreptococcus sp. Activity 0.0 % 10.1128/aac.00696-08
Peptostreptococcus sp. Peptostreptococcus sp. MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Peptostreptococcus sp. Peptostreptococcus sp. MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
Peptostreptococcus sp. Peptostreptococcus sp. MIC90 4.0 ug.mL-1 10.1128/aac.00696-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 0.3 % 10.1128/aac.01435-06
Phocaeicola vulgatus Phocaeicola vulgatus Activity 3.2 % 10.1128/aac.00696-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 7.0 % 10.1128/aac.00481-10
Phocaeicola vulgatus Phocaeicola vulgatus Activity 17.0 % 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 25.0 % 10.1128/aac.00481-10
Phocaeicola vulgatus Phocaeicola vulgatus MIC 1.0 ug.mL-1 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC 2.0 ug.mL-1 10.1128/aac.00696-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC 4.0 ug.mL-1 10.1128/aac.00481-10
Phocaeicola vulgatus Phocaeicola vulgatus MIC 8.0 ug.mL-1 10.1021/jm00068a009
Phocaeicola vulgatus Phocaeicola vulgatus MIC 10.5 ug.mL-1 10.1128/aac.01435-06
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 8.0 ug.mL-1 10.1128/aac.00696-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 16.0 ug.mL-1 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 32.0 ug.mL-1 10.1128/aac.00481-10
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 32.0 ug.mL-1 10.1128/aac.00481-10
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 32.0 ug.mL-1 10.1128/aac.00696-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 32.0 ug.mL-1 10.1128/aac.01435-06
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 64.0 ug.mL-1 10.1128/aac.00081-08
Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Prevotella Prevotella MIC 1.0 ug.mL-1 10.1128/aac.00336-08
Prevotella bivia Prevotella bivia Activity 0.0 % 10.1128/aac.00481-10
Prevotella bivia Prevotella bivia Activity 89.0 % 10.1128/aac.00481-10
Prevotella bivia Prevotella bivia MIC 0.5 ug.mL-1 10.1128/aac.00481-10
Prevotella bivia Prevotella bivia MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
Prevotella bivia Prevotella bivia MIC90 32.0 ug.mL-1 10.1128/aac.00481-10
Prevotella buccae Prevotella buccae Activity 0.0 % 10.1128/aac.00481-10
Prevotella buccae Prevotella buccae Activity 89.0 % 10.1128/aac.00481-10
Prevotella buccae Prevotella buccae MIC 0.5 ug.mL-1 10.1128/aac.00481-10
Prevotella buccae Prevotella buccae MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
Prevotella buccae Prevotella buccae MIC90 32.0 ug.mL-1 10.1128/aac.00481-10
Prevotella intermedia Prevotella intermedia Activity 0.0 % 10.1128/aac.00481-10
Prevotella intermedia Prevotella intermedia Activity 100.0 % 10.1128/aac.00481-10
Prevotella intermedia Prevotella intermedia MIC 0.5 ug.mL-1 10.1128/aac.00481-10
Prevotella intermedia Prevotella intermedia MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Prevotella intermedia Prevotella intermedia MIC90 4.0 ug.mL-1 10.1128/aac.00481-10
Prevotella melaninogenica Prevotella melaninogenica MIC 4.0 ug.mL-1 10.1021/jm00068a009
Prevotella melaninogenica Prevotella melaninogenica MIC 8.0 ug.mL-1 10.1021/jm00068a009
Propionibacterium Propionibacterium Activity 0.0 % 10.1128/aac.00696-08
Propionibacterium Propionibacterium MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Propionibacterium Propionibacterium MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
Propionibacterium Propionibacterium MIC90 1.0 ug.mL-1 10.1128/aac.00696-08
Proteus Proteus Relative potency 0.6 None 10.1016/S0960-894X(01)80923-9
Proteus mirabilis Proteus mirabilis Activity 0.0 % 10.1128/aac.01509-06
Proteus mirabilis Proteus mirabilis Activity 95.0 % 10.1128/aac.00426-09
Proteus mirabilis Proteus mirabilis Activity 100.0 % 10.1128/aac.01808-09
Proteus mirabilis Proteus mirabilis MIC 1.56 ug.mL-1 10.1021/jm00214a018
Proteus mirabilis Proteus mirabilis MIC 2.0 ug.mL-1 10.1128/aac.01400-08
Proteus mirabilis Proteus mirabilis MIC 2.0 ug.mL-1 10.1128/aac.01431-06
Proteus mirabilis Proteus mirabilis MIC 4.0 ug.mL-1 10.1128/aac.01399-07
Proteus mirabilis Proteus mirabilis MIC 4.0 ug.mL-1 10.1128/aac.01431-06
Proteus mirabilis Proteus mirabilis MIC 128.0 ug.mL-1 10.1128/aac.00111-10
Proteus mirabilis Proteus mirabilis MIC50 2.0 ug.mL-1 10.1128/aac.01509-06
Proteus mirabilis Proteus mirabilis MIC90 8.0 ug.mL-1 10.1128/aac.01509-06
Proteus vulgaris Proteus vulgaris MIC 0.39 ug.mL-1 10.1021/jm00214a018
Providencia Providencia MIC 1.56 ug.mL-1 10.1021/jm00214a018
Providencia rettgeri Providencia rettgeri MIC 128.0 ug.mL-1 10.1128/aac.01312-09
Providencia stuartii Providencia stuartii MIC 128.0 ug.mL-1 10.1128/aac.00017-09
Pseudomonas Pseudomonas MIC 100.0 ug.mL-1 10.1021/jm00214a018
Pseudomonas aeruginosa Beta-lactamase Kcat 0.01 /s 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase Kcat 0.08 /s 10.1128/aac.01410-08
Pseudomonas aeruginosa Beta-lactamase Kcat/Km 160.0 /uM/s 10.1128/aac.01410-08
Pseudomonas aeruginosa Beta-lactamase Kcat/Km nan None 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase Km 500.0 nM 10.1128/aac.01410-08
Pseudomonas aeruginosa Beta-lactamase Km nan None 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase bla(BEL1) Kcat 0.01 /s 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase bla(BEL1) Kcat/Km nan None 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase bla(BEL1) Km nan None 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat 15.0 /s 10.1128/aac.00166-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat/Km 1.2 /uM/s 10.1128/aac.00166-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Km 13000.0 nM 10.1128/aac.00166-08
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-11 Kcat 6.4 /s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-11 Kcat/Km 8.6 10'6/M/s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-11 Km 7400.0 nM 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-2 Kcat 10.0 /s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-2 Kcat/Km 1.0 10'6/M/s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-2 Km 9900.0 nM 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-b-lactamase Kcat 10.0 /s 10.1128/aac.00166-08
Pseudomonas aeruginosa Metallo-b-lactamase Kcat/Km 0.15 /uM/s 10.1128/aac.00166-08
Pseudomonas aeruginosa Metallo-b-lactamase Km 68000.0 nM 10.1128/aac.00166-08
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1128/aac.00426-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1128/aac.01808-09
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 1.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 1.6 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 2.7 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 3.3 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 24.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 50.0 None 10.1128/aac.00296-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 50.0 None 10.1128/aac.01104-09
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 54.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 78.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 81.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 95.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 99.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 120.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 134.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 134.0 None 10.1128/aac.01104-09
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 189.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 232.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 232.0 None 10.1128/aac.01104-09
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 418.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 469.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 483.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 661.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 905.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 906.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 1014.0 None 10.1128/aac.01104-09
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 1105.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 1105.0 None 10.1128/aac.01104-09
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 1950.0 None 10.1128/aac.00385-10
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 1950.0 None 10.1128/aac.01104-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.01451-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.01011-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.01451-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.01451-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/jm00068a009
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1128/aac.00033-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1128/aac.00859-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 600.0 ug.mL-1 10.1128/aac.01617-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 800.0 ug.mL-1 10.1128/aac.01617-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1200.0 ug.mL-1 10.1128/aac.01617-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1600.0 ug.mL-1 10.1128/aac.01617-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2400.0 ug.mL-1 10.1128/aac.01617-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 3200.0 ug.mL-1 10.1128/aac.01617-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 20000.0 nM 10.6019/CHEMBL4513161
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 200000.0 nM 10.1016/j.ejmech.2022.114333
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1128/aac.00734-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1128/aac.01561-09
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 0.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 2.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 3.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 4.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 5.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 8.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 10.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 36.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 38.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 95.0 nmol 10.1128/aac.01617-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 152.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 165.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 230.0 nmol 10.1128/aac.01617-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 372.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 747.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 879.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 1019.0 nmol 10.1128/aac.01617-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 1068.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 1219.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 1303.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 2573.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 2981.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 3007.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 3022.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 3250.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 3438.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 3600.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 3935.0 nmol 10.1128/aac.01617-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 8130.0 nmol/min 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity nan None 10.1128/aac.00009-10
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat 0.015 /s 10.1128/aac.01410-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat/Km 30.0 /uM/s 10.1128/aac.01410-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Km 500.0 nM 10.1128/aac.01410-08
Pseudomonas fluorescens Beta-lactamase Kcat/Km 1.0 /mM/s 10.1128/aac.00961-09
Pseudomonas fluorescens Pseudomonas fluorescens Activity nan None 10.1128/aac.01808-09
Pseudomonas fluorescens Pseudomonas fluorescens MIC 256.0 ug.mL-1 10.1128/aac.00961-09
Pseudomonas putida Pseudomonas putida MIC 32.0 ug.mL-1 10.1128/aac.00931-08
Pseudomonas stutzeri Metallo-beta-lactamase Kcat 8.0 /s 10.1128/aac.01456-09
Pseudomonas stutzeri Metallo-beta-lactamase Km 20000.0 nM 10.1128/aac.01456-09
Pseudomonas stutzeri Metallo-beta-lactamase Ratio 400.0 None 10.1128/aac.01456-09
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Salmonella enterica Salmonella enterica MIC 16.0 ug.mL-1 10.1128/aac.00310-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 0.5 ug.mL-1 10.1128/aac.00600-06
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 1.0 ug.mL-1 10.1128/aac.00600-06
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 2.0 ug.mL-1 10.1128/aac.00600-06
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 4.0 ug.mL-1 10.1128/aac.00600-06
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 16.0 ug.mL-1 10.1128/aac.00600-06
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Ratio 4.0 None 10.1016/j.ejmech.2012.03.008
Schaalia meyeri Schaalia meyeri Activity 0.0 % 10.1128/aac.00481-10
Schaalia meyeri Schaalia meyeri Activity 92.0 % 10.1128/aac.00481-10
Schaalia meyeri Schaalia meyeri MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Schaalia meyeri Schaalia meyeri MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Schaalia meyeri Schaalia meyeri MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Serratia Serratia MIC 25.0 ug.mL-1 10.1021/jm00214a018
Serratia Serratia Relative potency 0.3 None 10.1016/S0960-894X(01)80923-9
Serratia fonticola Carbapenem-hydrolizing beta-lactamase SFC-1 Kcat 4.2 /s 10.1128/aac.00491-07
Serratia fonticola Carbapenem-hydrolizing beta-lactamase SFC-1 Kcat/Km 54.5 /mM/s 10.1128/aac.00491-07
Serratia fonticola Carbapenem-hydrolizing beta-lactamase SFC-1 Km 77000.0 nM 10.1128/aac.00491-07
Serratia marcescens Serratia marcescens Activity 26.0 % 10.1128/aac.01808-09
Serratia marcescens Serratia marcescens MIC 4.0 ug.mL-1 10.1128/aac.00768-10
Serratia marcescens Serratia marcescens MIC 16.0 ug.mL-1 10.1128/aac.01539-07
Serratia marcescens Serratia marcescens MIC 256.0 ug.mL-1 10.1128/aac.00768-10
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 4.46 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 0.25 % 10.6019/CHEMBL4495565
Shigella sonnei Shigella sonnei MIC 2.0 ug.mL-1 10.1128/aac.00227-08
Shouchella clausii Shouchella clausii MIC 16000.0 ug.mL-1 10.1128/aac.00537-07
Shouchella clausii Shouchella clausii MIC 32000.0 ug.mL-1 10.1128/aac.00537-07
Staphylococcus aureus Staphylococcus aureus Activity 1.84 mg/L 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus Activity 200.0 mg/L 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus EC50 0.55 ug.mL-1 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus FC 4.0 None 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus FC 512.0 None 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus GI nan None 10.1016/j.bmc.2015.04.069
Staphylococcus aureus Staphylococcus aureus IZ 13.0 mm 10.1128/aac.00040-07
Staphylococcus aureus Staphylococcus aureus IZ 22.0 mm 10.1016/j.bmcl.2011.11.059
Staphylococcus aureus Staphylococcus aureus IZ 33.0 mm 10.1016/j.bmcl.2011.11.059
Staphylococcus aureus Staphylococcus aureus IZ nan None 10.1021/np900382x
Staphylococcus aureus Staphylococcus aureus log10cfu -0.91 None 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus log10cfu 2.36 None 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus log10cfu 3.06 None 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus MBC 256.0 ug ml-1 10.1128/aac.00049-08
Staphylococcus aureus Staphylococcus aureus MIC 0.032 ug.mL-1 10.1128/aac.01173-08
Staphylococcus aureus Staphylococcus aureus MIC 0.256 ug.mL-1 10.1128/aac.01173-08
Staphylococcus aureus Staphylococcus aureus MIC 0.78 ug.mL-1 10.1016/S0960-894X(01)80927-6
Staphylococcus aureus Staphylococcus aureus MIC 1.5 ug.mL-1 10.1128/aac.01099-08
Staphylococcus aureus Staphylococcus aureus MIC 1.56 ug.mL-1 10.1016/S0960-894X(01)80927-6
Staphylococcus aureus Staphylococcus aureus MIC 1.56 ug.mL-1 10.1021/jm00214a018
Staphylococcus aureus Staphylococcus aureus MIC 3.0 ug.mL-1 10.1128/aac.01099-08
Staphylococcus aureus Staphylococcus aureus MIC 3.12 ug.mL-1 10.1016/j.bmcl.2023.129167
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/jm00068a009
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.00594-10
Staphylococcus aureus Staphylococcus aureus MIC 6.0 ug.mL-1 10.1128/aac.01099-08
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1016/S0960-894X(01)80927-6
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00594-10
Staphylococcus aureus Staphylococcus aureus MIC 12.5 ug.mL-1 10.1016/S0960-894X(01)80927-6
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1128/aac.00049-08
Staphylococcus aureus Staphylococcus aureus MIC 25.0 ug.mL-1 10.1016/j.bmcl.2023.129167
Staphylococcus aureus Staphylococcus aureus MIC 25.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1021/acsmedchemlett.1c00680
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.00040-07
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.00049-08
Staphylococcus aureus Staphylococcus aureus MIC 50.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/acsmedchemlett.1c00680
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.00049-08
Staphylococcus aureus Staphylococcus aureus MIC 100.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1128/aac.00049-08
Staphylococcus aureus Staphylococcus aureus MIC 200.0 ug.mL-1 10.1128/aac.01099-08
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1021/acsmedchemlett.1c00680
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1128/aac.00594-10
Staphylococcus aureus Staphylococcus aureus MIC 400.0 ug.mL-1 10.1128/aac.01099-08
Staphylococcus aureus Staphylococcus aureus MIC 800.0 ug.mL-1 10.1128/aac.01099-08
Staphylococcus aureus Staphylococcus aureus MIC 20000.0 nM 10.6019/CHEMBL4513161
Staphylococcus aureus Staphylococcus aureus MIC 25000.0 nM 10.1016/j.ejmech.2022.114333
Staphylococcus aureus Staphylococcus aureus MIC 100000.0 nM 10.1016/j.ejmech.2022.114333
Staphylococcus aureus Staphylococcus aureus Relative potency 0.03 None 10.1016/S0960-894X(01)80923-9
Staphylococcus epidermidis Staphylococcus epidermidis MIC 4.0 ug.mL-1 10.1021/jm00068a009
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 8.0 ug.mL-1 10.1128/aac.01150-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 16.0 ug.mL-1 10.1128/aac.01150-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 32.0 ug.mL-1 10.1128/aac.01150-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC50 2.0 ug.mL-1 10.1128/aac.01150-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC90 2.0 ug.mL-1 10.1128/aac.01150-07
Stenotrophomonas maltophilia Beta-lactamase L1 Kcat/Km 5.5 10'5/M/s 10.1128/aac.01062-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity nan None 10.1128/aac.00682-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity nan None 10.1128/aac.01485-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity nan None 10.1128/aac.01808-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 32.0 ug.mL-1 10.1128/aac.01283-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 64.0 ug.mL-1 10.1128/aac.01283-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 128.0 ug.mL-1 10.1128/aac.00682-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 1024.0 ug.mL-1 10.1128/aac.00682-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 1024.0 ug.mL-1 10.1128/aac.01283-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 1024.0 ug.mL-1 10.1128/aac.01513-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Ratio 0.2 None 10.1128/aac.00682-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1021/jm00068a009
Streptococcus pyogenes Streptococcus pyogenes MIC 0.78 ug.mL-1 10.1021/jm00214a018
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 2.0 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 4.0 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 8.0 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 16.0 ug.mL-1 10.1128/aac.00461-08
Stutzerimonas stutzeri Stutzerimonas stutzeri MIC 512.0 ug.mL-1 10.1128/aac.01456-09
Veillonella Veillonella MIC 1.0 ug.mL-1 10.1128/aac.00336-08
None ADMET CL 3.6 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET MRT 0.79 hr 10.1124/dmd.108.020479
None ADMET T1/2 0.81 hr 10.1124/dmd.108.020479
None ADMET Vdss 0.17 L.kg-1 10.1124/dmd.108.020479
None Erythrocyte HC10 20.0 uM 10.6019/CHEMBL4513161
None Hepatotoxicity Alkaline Phosphatase Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Active 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Marginal 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx1000865
None Hepatotoxicity Hepatotoxicity nan None 10.1124/dmd.110.035113
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LDH Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None NON-PROTEIN TARGET Activity 0.0 % 10.1128/aac.00481-10
None NON-PROTEIN TARGET Activity 0.0 % 10.1128/aac.00696-08
None NON-PROTEIN TARGET Activity 10.9 % 10.1128/aac.01435-06
None NON-PROTEIN TARGET Activity 23.9 % 10.1128/aac.00081-08
None NON-PROTEIN TARGET Activity 55.6 % 10.1128/aac.00696-08
None NON-PROTEIN TARGET Activity 92.0 % 10.1128/aac.00481-10
None NON-PROTEIN TARGET Fu 0.73 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 0.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 18.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 25.8 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.00481-10
None NON-PROTEIN TARGET MIC 0.13 ug.mL-1 10.1128/aac.00481-10
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1021/jm00068a009
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00791-09
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.01585-09
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.00696-08
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.01152-06
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.01615-09
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1021/jm00068a009
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.00081-08
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1021/jm00068a009
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.00696-08
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.01252-09
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.01581-08
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC 17.61 ug.mL-1 10.1128/aac.01435-06
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1128/aac.00427-09
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1128/aac.01252-09
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.00049-08
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.00734-08
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.01463-07
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.00049-08
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.01284-08
None NON-PROTEIN TARGET MIC 512.0 ug.mL-1 10.1128/aac.01600-06
None NON-PROTEIN TARGET MIC50 0.064 ug.mL-1 10.1128/aac.00056-07
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
None NON-PROTEIN TARGET MIC50 16.0 ug.mL-1 10.1128/aac.00081-08
None NON-PROTEIN TARGET MIC50 16.0 ug.mL-1 10.1128/aac.00696-08
None NON-PROTEIN TARGET MIC50 64.0 ug.mL-1 10.1128/aac.00696-08
None NON-PROTEIN TARGET MIC50 256.0 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC90 0.38 ug.mL-1 10.1128/aac.00056-07
None NON-PROTEIN TARGET MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
None NON-PROTEIN TARGET MIC90 32.0 ug.mL-1 10.1128/aac.00696-08
None NON-PROTEIN TARGET MIC90 64.0 ug.mL-1 10.1128/aac.00081-08
None NON-PROTEIN TARGET MIC90 64.0 ug.mL-1 10.1128/aac.01435-06
None NON-PROTEIN TARGET MIC90 128.0 ug.mL-1 10.1128/aac.00696-08
None NON-PROTEIN TARGET MIC90 256.0 ug.mL-1 10.1128/aac.00630-09
None Unchecked Ac50 0.3981 uM None
None Unchecked Ac50 4.467 uM None
None Unchecked Ac50 44.67 uM None
None Unchecked AC50 400.0 nM None
None Unchecked AC50 4466.8 nM None
None Unchecked AC50 44668.4 nM None
None Unchecked Activity nan None 10.1128/aac.01145-07
None Unchecked Activity nan None 10.1128/aac.01463-07
None Unchecked Hepatotoxicity (acute) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Kcat 0.01 /s 10.1128/aac.00387-08
None Unchecked Kcat 0.01 /s 10.1128/aac.00856-09
None Unchecked Kcat 0.01 /s 10.1128/aac.01463-07
None Unchecked Kcat 0.01 /s 10.1128/aac.01600-06
None Unchecked Kcat 0.08 /s 10.1128/aac.00608-08
None Unchecked Kcat 0.08 /s 10.1128/aac.01410-08
None Unchecked Kcat 0.1 /s 10.1128/aac.00608-08
None Unchecked Kcat 0.2 /s 10.1128/aac.01252-09
None Unchecked Kcat 0.28 /s 10.1128/aac.00219-09
None Unchecked Kcat 0.3 /s 10.1128/aac.00608-08
None Unchecked Kcat 0.35 /s 10.1128/aac.00219-09
None Unchecked Kcat 0.4 /s 10.1128/aac.00608-08
None Unchecked Kcat 0.5 /s 10.1128/aac.01252-09
None Unchecked Kcat 0.5 /s 10.1128/aac.01410-08
None Unchecked Kcat 0.88 /s 10.1128/aac.01252-09
None Unchecked Kcat 1.0 /s 10.1128/aac.00961-09
None Unchecked Kcat 2.0 /s 10.1128/aac.00858-10
None Unchecked Kcat 4.0 /s 10.1128/aac.00017-09
None Unchecked Kcat 7.0 /s 10.1128/aac.01062-07
None Unchecked Kcat 7.0 /s 10.1128/aac.01462-06
None Unchecked Kcat 7.5 /s 10.1128/aac.00771-10
None Unchecked Kcat 9.0 /s 10.1128/aac.01336-09
None Unchecked Kcat 12.1 /s 10.1128/aac.00771-10
None Unchecked Kcat 16.0 /s 10.1128/aac.00774-09
None Unchecked Kcat 16.0 /s 10.1128/aac.00858-10
None Unchecked Kcat 26.0 /s 10.1128/aac.00166-08
None Unchecked Kcat 40.0 /s 10.1128/aac.01336-09
None Unchecked Kcat 1178.0 /s 10.1128/aac.01337-07
None Unchecked Kcat nan None 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.03 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.08 /s/microM 10.1128/aac.00017-09
None Unchecked Kcat/Km 0.1 /mM/s 10.1128/aac.00608-08
None Unchecked Kcat/Km 0.15 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.2 /uM/s 10.1128/aac.00166-08
None Unchecked Kcat/Km 0.3 /mM/s 10.1128/aac.00608-08
None Unchecked Kcat/Km 0.86 /s/M 10.1128/aac.01025-07
None Unchecked Kcat/Km 0.9 uM/hr 10.1128/aac.01336-09
None Unchecked Kcat/Km 1.0 /uM/s 10.1128/aac.00050-10
None Unchecked Kcat/Km 1.0 None 10.1128/aac.01462-06
None Unchecked Kcat/Km 1.3 10'6/M/s 10.1128/aac.01252-09
None Unchecked Kcat/Km 1.4 10'7/M/s 10.1128/aac.01337-07
None Unchecked Kcat/Km 1.6 /uM/s 10.1128/aac.00219-09
None Unchecked Kcat/Km 1.8 10'5/M/s 10.1128/aac.00858-10
None Unchecked Kcat/Km 2.0 10'6/M/s 10.1128/aac.00858-10
None Unchecked Kcat/Km 2.0 /s/microM 10.1128/aac.00774-09
None Unchecked Kcat/Km 2.3 /uM/s 10.1128/aac.00219-09
None Unchecked Kcat/Km 3.0 10'5/M/s 10.1128/aac.01252-09
None Unchecked Kcat/Km 3.0 uM/hr 10.1128/aac.01336-09
None Unchecked Kcat/Km 3.5 10'7/M/s 10.1128/aac.01252-09
None Unchecked Kcat/Km 4.7 10'3/M/s 10.1128/aac.01062-07
None Unchecked Kcat/Km 7.1 10'4/M/s 10.1128/aac.01062-07
None Unchecked Kcat/Km 10.0 /uM/s 10.1128/aac.01585-09
None Unchecked Kcat/Km 160.0 /uM/s 10.1128/aac.01410-08
None Unchecked Kcat/Km 200.0 /uM/s 10.1128/aac.01410-08
None Unchecked Kcat/Km nan None 10.1128/aac.00387-08
None Unchecked Kcat/Km nan None 10.1128/aac.00771-10
None Unchecked Kcat/Km nan None 10.1128/aac.01082-06
None Unchecked Ki 150.0 nM 10.1128/aac.00219-09
None Unchecked Ki 170.0 nM 10.1128/aac.00219-09
None Unchecked Km 25.0 nM 10.1128/aac.01252-09
None Unchecked Km 400.0 nM 10.1128/aac.01252-09
None Unchecked Km 500.0 nM 10.1128/aac.01410-08
None Unchecked Km 650.0 nM 10.1128/aac.01252-09
None Unchecked Km 3000.0 nM 10.1128/aac.01336-09
None Unchecked Km 7000.0 nM 10.1128/aac.01462-06
None Unchecked Km 8000.0 nM 10.1128/aac.00774-09
None Unchecked Km 8000.0 nM 10.1128/aac.00858-10
None Unchecked Km 11000.0 nM 10.1128/aac.00858-10
None Unchecked Km 45000.0 nM 10.1128/aac.01336-09
None Unchecked Km 81000.0 nM 10.1128/aac.01337-07
None Unchecked Km 82300.0 nM 10.1128/aac.00771-10
None Unchecked Km 130000.0 nM 10.1128/aac.00166-08
None Unchecked Km 221000.0 nM 10.1128/aac.00771-10
None Unchecked Km 700000.0 nM 10.1128/aac.00608-08
None Unchecked Km 800000.0 nM 10.1128/aac.00608-08
None Unchecked Km 825000.0 nM 10.1128/aac.00961-09
None Unchecked Km 1000000.0 nM 10.1128/aac.00608-08
None Unchecked Km 1500000.0 nM 10.1128/aac.00608-08
None Unchecked Km 1570000.0 nM 10.1128/aac.01062-07
None Unchecked Km nan None 10.1128/aac.00387-08
None Unchecked Km nan None 10.1128/aac.00389-07
None Unchecked Km nan None 10.1128/aac.00771-10
None Unchecked Km nan None 10.1128/aac.00856-09
None Unchecked Km nan None 10.1128/aac.01082-06
None Unchecked Km nan None 10.1128/aac.01463-07
None Unchecked Km nan None 10.1128/aac.01600-06
None Unchecked Ratio 4.0 None 10.1128/aac.00614-07
None Unchecked Vmax 0.002 nmol 10.1128/aac.00389-07
None Unchecked Vmax/Km nan None 10.1128/aac.00389-07

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT011276 CO[C@@]1(NC(=O)Cc2cccs2)C(=O)N2C(C(=O)O)=C(COC(N)=O)CS[C@@H]21>>CO[C@@](NC(=O)Cc1cccs1)(C(=O)O)[C@@H]1NC(C(=O)O)=C(COC(N)=O)CS1 enzymemap_78561