Navigation

name Structure Reference Source Properties Activities Metabolism

Enopeptin A

AlkaPlorer ID: AK005983

Synonym: None

IUPAC Name: (2E,4E,6E,8E,10E)-N-(2-hydroxy-5-oxocyclopenten-1-yl)-N'-[(2S)-1-oxo-3-phenyl-1-[[(3S,7S,9R,13S,16S,19S)-9,13,16,17-tetramethyl-2,6,12,15,18-pentaoxo-5-oxa-1,11,14,17-tetrazatricyclo[17.3.0.07,11]docosan-3-yl]amino]propan-2-yl]dodeca-2,4,6,8,10-pentaenediamide

Structure

SMILES: C[C@@H]1C[C@H]2C(=O)OC[C@H](NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)/C=C/C=C/C=C/C=C/C=C/C(=O)NC3=C(O)CCC3=O)C(=O)N3CCC[C@H]3C(=O)N(C)[C@@H](C)C(=O)N[C@@H](C)C(=O)N2C1

copy

InChI: InChI=1S/C47H57N7O11/c1-29-25-36-47(64)65-28-34(45(62)53-24-16-19-35(53)46(63)52(4)31(3)42(59)48-30(2)44(61)54(36)27-29)50-43(60)33(26-32-17-12-11-13-18-32)49-39(57)20-14-9-7-5-6-8-10-15-21-40(58)51-41-37(55)22-23-38(41)56/h5-15,17-18,20-21,29-31,33-36,55H,16,19,22-28H2,1-4H3,(H,48,59)(H,49,57)(H,50,60)(H,51,58)/b6-5+,9-7+,10-8+,20-14+,21-15+/t29-,30+,31+,33+,34+,35+,36+/m1/s1

copy

InChIKey: ODKIYTBYJKALOK-BKZRIAMSSA-N

copy

Source

Species Genus Family Order Class Phylum Kingdom Domain
Streptomyces sp. Streptomyces Streptomycetaceae Kitasatosporales Actinomycetes Actinomycetota None Bacteria

Properties Information

Molecule Weight: 896.0109999999995

TPSA？: 240.93

MolLogP？: 1.364800000000007

Number of H-Donors: 5

Number of H-Acceptors: 11

RingCount: 5

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Escherichia coli (strain K12) ATP-dependent Clp protease proteolytic subunit EC50 100.0 nM 10.1021/acs.jnatprod.5b01091
Escherichia coli (strain K12) ATP-dependent Clp protease proteolytic subunit EC50 1200.0 nM 10.1021/acs.jnatprod.5b01091
Escherichia coli (strain K12) ATP-dependent Clp protease proteolytic subunit Ratio EC50 10.0 None 10.1021/acs.jnatprod.5b01091

Metabolism Information