N-Acetyl-L-tyrosine
AlkaPlorer ID: AK006136
Synonym: None
IUPAC Name: (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid
Structure
SMILES: CC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O
InChI: InChI=1S/C11H13NO4/c1-7(13)12-10(11(15)16)6-8-2-4-9(14)5-3-8/h2-5,10,14H,6H2,1H3,(H,12,13)(H,15,16)/t10-/m0/s1
InChIKey: CAHKINHBCWCHCF-JTQLQIEISA-N
Reference
UHPLC-ESI Analysis and Antifungal Activity of Cladodes and Callus Cultures of Cereus hildmannianus
PubChem CID: 68310
CAS: 36174-18-2
data_source: manually
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Cereus hildmannianus | Cereus | Cactaceae | Caryophyllales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 223.22799999999998
TPSA？: 86.63000000000001
MolLogP？: 0.5239999999999998
Number of H-Donors: 3
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Galactocerebrosidase | Potency | 707.9 | nM | None |
| Homo sapiens | Matrix metalloproteinase 3 | IC50 | 500000.0 | nM | 10.1021/jm00027a027 |
| Homo sapiens | SLC16A10 protein | Activity | 100.0 | % | 10.1006/geno.2001.6678 |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 21331.3 | nM | None |
| Rattus norvegicus | Monocarboxylate transporter 10 | Activity | 90.0 | % | 10.1074/jbc.m009462200 |
| Severe acute respiratory syndrome coronavirus 2 | Replicase polyprotein 1ab | Inhibition | 10.28 | % | 10.6019/CHEMBL4495564 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | Hit score | 0.135 | None | 10.1101/2020.04.21.054387 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | IC50 | 19952.62 | nM | 10.6019/CHEMBL4651402 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | IC50 | 20000.0 | nM | 10.6019/CHEMBL4651402 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | Inhibition | -8.83 | % | 10.21203/rs.3.rs-23951/v1 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | Inhibition | 0.03 | % | 10.6019/CHEMBL4495565 |
| Staphylococcus aureus | Staphylococcus aureus | Activity | 19.9 | % | 10.1128/aac.01293-08 |
| Staphylococcus aureus | Staphylococcus aureus | Activity | 47.5 | % | 10.1128/aac.01293-08 |
| Staphylococcus aureus | Staphylococcus aureus | Inhibition | 47.1 | % | 10.1128/aac.01293-08 |
| Staphylococcus aureus | Staphylococcus aureus | Inhibition | 71.5 | % | 10.1128/aac.01293-08 |