(S)-Norreticuline
AlkaPlorer ID: AK006252
Synonym: 'Norreticuline'
IUPAC Name: (1S)-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol
Structure
SMILES: COC1=CC=C(C[C@@H]2NCCC3=CC(OC)=C(O)C=C32)C=C1O
InChI: InChI=1S/C18H21NO4/c1-22-17-4-3-11(8-15(17)20)7-14-13-10-16(21)18(23-2)9-12(13)5-6-19-14/h3-4,8-10,14,19-21H,5-7H2,1-2H3/t14-/m0/s1
InChIKey: FVEMXQCEJGGXJB-AWEZNQCLSA-N
Reference
Biosynthesis of Erythrina alkaloids in Erythrina crista-galli
PubChem CID: 441069
CAS: 4781-58-2
LOTUS: LTS0229629
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Erythrina crista-galli | Erythrina | Fabaceae | Fabales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 315.369
TPSA？: 70.95
MolLogP？: 2.5445000000000007
Number of H-Donors: 3
Number of H-Acceptors: 5
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Rattus norvegicus | Adrenergic receptor alpha | Ki | 5000.0 | nM | 10.1021/jm00180a013 |
| Rattus norvegicus | Adrenergic receptor beta | Ki | 1300.0 | nM | 10.1021/jm00180a013 |
| Rattus norvegicus | Dopamine receptor | Ki | 1500.0 | nM | 10.1021/jm00180a013 |