3',5'-cyclic GMP(1-)
AlkaPlorer ID: AK006463
Synonym: '', "3',5'-cyclic GMP anion", "3',5'-Cyclic GMP", 'Guanosine cyclic monophosphate', "Guanosine 3',5'-cyclic monophosphate", "3',5'-cyclic GMP", 'Cyclic GMP', 'cGMP', "Guanosine 3',5'-cyclic phosphate"
IUPAC Name: 9-[(4aR,6S,7R,7aS)-2,7-dihydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-1H-purin-6-one
Structure
SMILES: N=C1N=C(O)C2=C(N1)N([C@H]1O[C@@H]3COP(=O)(O)O[C@H]3[C@H]1O)C=N2
InChI: InChI=1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)/t3-,5-,6-,9+/m1/s1
InChIKey: ZOOGRGPOEVQQDX-BDXYJKHTSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 345.208
TPSA？: 175.79999999999995
MolLogP？: -1.2814300000000007
Number of H-Donors: 5
Number of H-Acceptors: 10
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | G-protein coupled receptor kinase 2 | Inhibition | 24.2 | % | 10.1021/jm010093a |