Tenuazonic Acid
AlkaPlorer ID: AK006770
Synonym: None
IUPAC Name: (2S)-4-acetyl-2-[(2S)-butan-2-yl]-3-hydroxy-1,2-dihydropyrrol-5-one
Structure
SMILES: CC[C@H](C)[C@@H]1N=C(O)C(C(C)=O)=C1O
InChI: InChI=1S/C10H15NO3/c1-4-5(2)8-9(13)7(6(3)12)10(14)11-8/h5,8,13H,4H2,1-3H3,(H,11,14)/t5-,8-/m0/s1
InChIKey: CEIZFXOZIQNICU-XNCJUZBTSA-N
Reference
PubChem CID: 54683011
CAS: 1013-59-8
LOTUS: LTS0216774
SuperNatural Ⅲ: SN0043462-01
NPASS: NPC4706
{NPAtlas: NPA015602
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Alternaria sp. | Alternaria | Pleosporaceae | Pleosporales | Dothideomycetes | Ascomycota | Fungi | Eukaryota |
| None | Alternaria | Pleosporaceae | Pleosporales | Dothideomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 197.234
TPSA？: 69.89
MolLogP？: 1.7723
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Human gammaherpesvirus 4 | Human gammaherpesvirus 4 | Inhibition | 23.0 | % | 10.1021/acs.jnatprod.2c00783 |
| Mus musculus | BV-2 | Inhibition | 62.9 | % | 10.1021/acs.jnatprod.2c00783 |
| Mus musculus | L5178Y | Activity | 57.9 | % | 10.1021/np070447m |