Norcorydine
AlkaPlorer ID: AK006879
Synonym: '(+)-Norcorydine'
IUPAC Name: (6aS)-2,10,11-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol
Structure
SMILES: COC1=CC2=C3C(=C1O)C1=C(OC)C(OC)=CC=C1C[C@@H]3NCC2
InChI: InChI=1S/C19H21NO4/c1-22-13-5-4-10-8-12-15-11(6-7-20-12)9-14(23-2)18(21)17(15)16(10)19(13)24-3/h4-5,9,12,20-21H,6-8H2,1-3H3/t12-/m0/s1
InChIKey: HVMMFGYMZZVURQ-LBPRGKRZSA-N
Reference
Alkaloids of Corydalis marschalliana
PubChem CID: 179491
CAS: 26931-78-2
LOTUS: LTS0039213
SuperNatural Ⅲ: SN0136642-02
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Glaucium fimbrilligerum | Glaucium | Papaveraceae | Ranunculales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 327.3800000000001
TPSA？: 59.95
MolLogP？: 2.8279000000000005
Number of H-Donors: 2
Number of H-Acceptors: 5
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Entamoeba histolytica | Entamoeba histolytica | IC50 | 50.03 | ug.mL-1 | 10.1007/s00044-011-9767-1 |
| Entamoeba histolytica | Entamoeba histolytica | IC50 | 76400.0 | nM | 10.1021/np000144r |
| Homo sapiens | KB | IC50 | 733000.0 | nM | 10.1021/np000144r |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 3080.0 | nM | 10.1021/np000144r |