"1-methyl-4-methoxy-2-quinolone
AlkaPlorer ID: AK006991
Synonym: 'MLS000532185', 'N-Methyl-4-methoxycarbostyril', '1-Methyl-4-methoxy-2-quinolone', '4-methoxy-1-methyl-2(1H)-quinolinone', 'MLSMR', 'SMR000137126', '4-Methoxy-1-methyl-2-quinolone'
IUPAC Name: 4-methoxy-1-methylquinolin-2-one
Structure
SMILES: COC1=CC(=O)N(C)C2=CC=CC=C12
InChI: InChI=1S/C11H11NO2/c1-12-9-6-4-3-5-8(9)10(14-2)7-11(12)13/h3-7H,1-2H3
InChIKey: SPBLFONLHXBBQE-UHFFFAOYSA-N
Reference
Coumarins and Antiplatelet Constituents from the Root Bark of<i>Zanthoxylum schinifolium</i>
PubChem CID: 182073
CAS: 32262-18-3
LOTUS: LTS0090578
SuperNatural Ⅲ: SN0351569
COCONUT: CNP0413350
data_source: manually
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 189.21400000000003
TPSA？: 31.23
MolLogP？: 1.5471
Number of H-Donors: 0
Number of H-Acceptors: 3
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | DNA polymerase iota | Potency | 89125.1 | nM | None |
| Homo sapiens | Glycoprotein hormones alpha chain | Potency | 2238.7 | nM | None |
| Homo sapiens | HepG2 | IC50 | 160000.0 | nM | 10.1016/j.ejmech.2011.10.047 |
| Homo sapiens | Ubiquitin carboxyl-terminal hydrolase 1 | Potency | 794.3 | nM | None |
| Mus musculus | Nuclear receptor ROR-gamma | Potency | 12589.3 | nM | None |
| Staphylococcus aureus | Staphylococcus aureus | IC50 | 8000.0 | nM | 10.1016/j.ejmech.2018.08.061 |
| None | NON-PROTEIN TARGET | IC50 | 50000.0 | nM | 10.1021/np070594k |