8-Methylquinoline
AlkaPlorer ID: AK007498
Synonym: None
IUPAC Name: 8-methylquinoline
Structure
SMILES: CC1=C2C(=CC=C1)C=CC=N2
InChI: InChI=1S/C10H9N/c1-8-4-2-5-9-6-3-7-11-10(8)9/h2-7H,1H3
InChIKey: JRLTTZUODKEYDH-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Nitraria schoberi | Nitraria | Nitrariaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 143.18899999999996
TPSA？: 12.89
MolLogP？: 2.54322
Number of H-Donors: 0
Number of H-Acceptors: 1
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | 26S proteasome non-ATPase regulatory subunit 14 | IC50 | 100000.0 | nM | 10.1021/acs.jmedchem.6b01379 |
| Homo sapiens | ATPase family AAA domain-containing protein 5 | Potency | 11577.4 | nM | None |
| Homo sapiens | Chromobox protein homolog 1 | Potency | 89125.1 | nM | None |
| Homo sapiens | Geminin | Potency | 206.0 | nM | None |
| Homo sapiens | Geminin | Potency | 29092.9 | nM | None |
| Homo sapiens | HCT-116 | IC50 | 100000.0 | nM | 10.1021/acs.jmedchem.6b01379 |
| Homo sapiens | Nuclear factor erythroid 2-related factor 2 | Potency | 82.0 | nM | None |
| Homo sapiens | Nuclear factor erythroid 2-related factor 2 | Potency | 66824.2 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 3264.3 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 20786.5 | nM | None |