6-Benzyl-6,6a-dihydroisoindolo[2,1-a]quinazoline-5,11-dione
AlkaPlorer ID: AK007518
Synonym: None
IUPAC Name: 6-benzyl-6aH-isoindolo[2,3-a]quinazoline-5,11-dione
Structure
SMILES: C1=CC=C(C=C1)CN2C3C4=CC=CC=C4C(=O)N3C5=CC=CC=C5C2=O
InChI: InChI=1S/C22H16N2O2/c25-21-18-12-6-7-13-19(18)24-20(16-10-4-5-11-17(16)22(24)26)23(21)14-15-8-2-1-3-9-15/h1-13,20H,14H2
InChIKey: BLMZEXAIXSZDJW-UHFFFAOYSA-N
Reference
Synthesis of Isoindolo[2,1‐a]quinazoline Derivatives in Ionic Liquid Catalyzed by Iodine
PubChem CID: 3514191
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 340.38200000000006
TPSA？: 40.620000000000005
MolLogP？: 4.001600000000003
Number of H-Donors: 0
Number of H-Acceptors: 2
RingCount: 5
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | 4'-phosphopantetheinyl transferase ffp | Potency | 39810.7 | nM | None |
| Homo sapiens | Chromobox protein homolog 1 | Potency | 100000.0 | nM | None |
| Homo sapiens | Glucagon-like peptide 1 receptor | Potency | 12589.3 | nM | None |
| Homo sapiens | Guanine nucleotide-binding protein G(s), subunit alpha | Potency | 10000.0 | nM | None |
| Homo sapiens | Mothers against decapentaplegic homolog 3 | Potency | 35481.3 | nM | None |
| Homo sapiens | Rap guanine nucleotide exchange factor 4 | Potency | 56234.1 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 12995.3 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 29092.9 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 10417.9 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 16511.3 | nM | None |
| None | Unchecked | Potency | 10000.0 | nM | None |
| None | Unchecked | Potency | 25929.0 | nM | None |