Griseusrazin A
AlkaPlorer ID: AK007680
Synonym: None
IUPAC Name: N-[4-[[5-[[4-[formyl(methyl)amino]phenyl]methyl]-3,6-dimethylpyrazin-2-yl]methyl]phenyl]-N-methylformamide
Structure
SMILES: CC1=C(CC2=CC=C(N(C)C=O)C=C2)N=C(C)C(CC2=CC=C(N(C)C=O)C=C2)=N1
InChI: InChI=1S/C24H26N4O2/c1-17-23(13-19-5-9-21(10-6-19)27(3)15-29)26-18(2)24(25-17)14-20-7-11-22(12-8-20)28(4)16-30/h5-12,15-16H,13-14H2,1-4H3
InChIKey: CNVOHHZMQVBZQE-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces griseus | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 402.4980000000001
TPSA？: 66.4
MolLogP？: 3.4602400000000024
Number of H-Donors: 0
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Mus musculus | Nuclear factor erythroid 2-related factor 2 | Activity | None | None | 10.1021/acs.jnatprod.6b00009 |
| Mus musculus | RAW264.7 | Activity | None | None | 10.1021/acs.jnatprod.6b00009 |
| Mus musculus | Transcription factor p65 | Inhibition | None | % | 10.1021/acs.jnatprod.6b00009 |
| None | Unchecked | Inhibition | None | % | 10.1021/acs.jnatprod.6b00009 |