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Tobramycin

AlkaPlorer ID: AK007916

Synonym: None

IUPAC Name: (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol

Structure

SMILES: NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O

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InChI: InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1

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InChIKey: NLVFBUXFDBBNBW-PBSUHMDJSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain

Properties Information

Molecule Weight: 467.5200000000002

TPSA？: 268.1700000000001

MolLogP？: -6.295800000000006

Number of H-Donors: 10

Number of H-Acceptors: 14

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Acinetobacter Acinetobacter MIC 8.0 ug.mL-1 10.1128/aac.01634-07
Acinetobacter baumannii Acinetobacter baumannii Activity 60.4 % 10.1128/aac.00418-09
Acinetobacter baumannii Acinetobacter baumannii Activity 61.2 % 10.1128/aac.00570-08
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.00963-09
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.01398-09
Acinetobacter baumannii Acinetobacter baumannii FC 512.0 None 10.1021/acs.jmedchem.9b00876
Acinetobacter baumannii Acinetobacter baumannii Inhibition 100.0 % 10.1021/acs.jmedchem.2c01905
Acinetobacter baumannii Acinetobacter baumannii MBC 68.0 mg/L 10.1007/s00044-011-9933-5
Acinetobacter baumannii Acinetobacter baumannii MBC 78.1 mg/L 10.1007/s00044-011-9933-5
Acinetobacter baumannii Acinetobacter baumannii MBC 83.3 mg/L 10.1007/s00044-011-9933-5
Acinetobacter baumannii Acinetobacter baumannii MBC99.9 12.5 ug ml-1 10.1021/acs.jmedchem.6b01805
Acinetobacter baumannii Acinetobacter baumannii MBC99.9 25.0 ug ml-1 10.1021/acs.jmedchem.6b01805
Acinetobacter baumannii Acinetobacter baumannii MIC 0.12 ug.mL-1 10.1128/aac.00418-09
Acinetobacter baumannii Acinetobacter baumannii MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.9b00876
Acinetobacter baumannii Acinetobacter baumannii MIC 0.25 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 0.5 ug.mL-1 10.1039/D1MD00206F
Acinetobacter baumannii Acinetobacter baumannii MIC 0.5 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 0.75 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 0.75 ug.mL-1 10.1128/aac.01198-06
Acinetobacter baumannii Acinetobacter baumannii MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.9b00876
Acinetobacter baumannii Acinetobacter baumannii MIC 1.0 ug.mL-1 10.1039/C5MD00377F
Acinetobacter baumannii Acinetobacter baumannii MIC 1.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 1.0 ug.mL-1 10.1128/aac.01407-08
Acinetobacter baumannii Acinetobacter baumannii MIC 1.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 1.5 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 3.0 ug.mL-1 10.1128/aac.01198-06
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.01198-06
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 6.0 ug.mL-1 10.1128/aac.01198-06
Acinetobacter baumannii Acinetobacter baumannii MIC 6.25 ug.mL-1 10.1021/acs.jmedchem.6b01805
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1039/C5MD00377F
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.01198-06
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.01634-07
Acinetobacter baumannii Acinetobacter baumannii MIC 12.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.00838-06
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.01198-06
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 24.0 ug.mL-1 10.1128/aac.01198-06
Acinetobacter baumannii Acinetobacter baumannii MIC 25.0 ug.mL-1 10.1021/acs.jmedchem.6b01805
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.01139-06
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.01684-07
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.00072-08
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 96.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 512.0 ug.mL-1 10.1128/aac.00560-07
Acinetobacter baumannii Acinetobacter baumannii MIC 2500.0 nM 10.6019/CHEMBL4513161
Acinetobacter baumannii Acinetobacter baumannii MIC 6250.0 nM 10.1016/j.bmc.2009.12.003
Acinetobacter baumannii Acinetobacter baumannii MIC 25000.0 nM 10.1016/j.bmc.2009.12.003
Acinetobacter baumannii Acinetobacter baumannii MIC 200000.0 nM 10.1016/j.bmc.2009.12.003
Acinetobacter baumannii Acinetobacter baumannii MIC 400000.0 nM 10.1016/j.bmc.2009.12.003
Acinetobacter baumannii Acinetobacter baumannii MIC50 4.0 ug.mL-1 10.1128/aac.00418-09
Acinetobacter baumannii Acinetobacter baumannii MIC80 3100.0 nM 10.1039/c9md00341j
Acinetobacter baumannii Acinetobacter baumannii MIC90 64.0 ug.mL-1 10.1128/aac.00418-09
Acinetobacter baumannii Acinetobacter baumannii Survival 100.0 % 10.1021/acs.jmedchem.6b01805
Acinetobacter calcoaceticus Acinetobacter calcoaceticus Activity 92.6 % 10.1128/aac.00418-09
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC90 1.0 ug.mL-1 10.1128/aac.00418-09
Acinetobacter lwoffii Acinetobacter lwoffii Activity 94.0 % 10.1128/aac.00418-09
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.25 ug.mL-1 10.1016/j.ejmech.2018.08.022
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00818
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.5 ug.mL-1 10.1016/j.ejmech.2018.08.022
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.6b00818
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.5 ug.mL-1 10.1021/jm401148j
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.5 ug.mL-1 10.1021/jm900615h
Acinetobacter lwoffii Acinetobacter lwoffii MIC 1.0 ug.mL-1 10.1021/jm401148j
Acinetobacter lwoffii Acinetobacter lwoffii MIC 1.0 ug.mL-1 10.1021/jm900615h
Acinetobacter lwoffii Acinetobacter lwoffii MIC 1.0 ug.mL-1 10.1128/aac.00598-10
Acinetobacter lwoffii Acinetobacter lwoffii MIC 2.0 ug.mL-1 10.1128/aac.00598-10
Acinetobacter lwoffii Acinetobacter lwoffii MIC 4.0 ug.mL-1 10.1128/aac.00598-10
Acinetobacter lwoffii Acinetobacter lwoffii MIC 8.0 ug.mL-1 10.1128/aac.00598-10
Acinetobacter lwoffii Acinetobacter lwoffii MIC 16.0 ug.mL-1 10.1128/aac.00598-10
Acinetobacter lwoffii Acinetobacter lwoffii MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Acinetobacter lwoffii Acinetobacter lwoffii MIC90 0.5 ug.mL-1 10.1128/aac.00418-09
Acinetobacter pittii Acinetobacter pittii Activity 42.1 % 10.1128/aac.01624-09
Acinetobacter pittii Acinetobacter pittii MIC 0.25 ug.mL-1 10.1128/aac.00072-08
Acinetobacter pittii Acinetobacter pittii MIC 0.5 ug.mL-1 10.1128/aac.01624-09
Acinetobacter pittii Acinetobacter pittii MIC50 8.0 ug.mL-1 10.1128/aac.01624-09
Acinetobacter pittii Acinetobacter pittii MIC90 16.0 ug.mL-1 10.1128/aac.01624-09
Acinetobacter radioresistens Acinetobacter radioresistens MIC 2.0 ug.mL-1 10.1128/aac.00999-08
Acinetobacter sp. Acinetobacter sp. Activity 66.0 % 10.1128/aac.01398-09
Acinetobacter sp. Acinetobacter sp. MIC 8.0 ug.mL-1 10.1128/aac.00838-06
Acinetobacter sp. Acinetobacter sp. MIC 16.0 ug.mL-1 10.1128/aac.00838-06
Aeromonas caviae Aeromonas caviae MIC 32.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Aeromonas hydrophila Aeromonas hydrophila MIC 16.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Aspergillus niger Aspergillus niger MIC nan None 10.1021/acs.jnatprod.6b00200
Bacillus anthracis Bacillus anthracis MIC 9.4 ug.mL-1 10.1021/jm400707f
Bacillus anthracis Bacillus anthracis MIC 128.0 ug.mL-1 10.1021/acsmedchemlett.5b00255
Bacillus cereus Bacillus cereus IZ 19.0 mm 10.1007/s00044-011-9911-y
Bacillus cereus Bacillus cereus MIC 9.4 ug.mL-1 10.1021/acsmedchemlett.5b00255
Bacillus cereus Bacillus cereus MIC 75.0 ug.mL-1 10.1021/jm400707f
Bacillus subtilis Bacillus subtilis Kd 38000.0 nM 10.1016/j.bmcl.2005.02.007
Bacillus subtilis Bacillus subtilis MIC 2.3 ug.mL-1 10.1021/jm400707f
Bacillus subtilis Bacillus subtilis MIC 3.0 ug.mL-1 10.1016/j.bmcl.2015.10.087
Bacillus subtilis Bacillus subtilis MIC 9.4 ug.mL-1 10.1021/acsmedchemlett.5b00255
Bacillus subtilis Bacillus subtilis MIC 9.4 ug.mL-1 10.1021/jm400707f
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Burkholderia cepacia Burkholderia cepacia INH 64.0 ug ml-1 10.1016/j.bmc.2019.115229
Burkholderia cepacia Burkholderia cepacia MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Burkholderia cepacia Burkholderia cepacia MIC 40.0 ug.mL-1 10.1021/jm200506x
Burkholderia cepacia Burkholderia cepacia MIC50 32.0 ug.mL-1 10.1128/aac.00248-09
Burkholderia cepacia Burkholderia cepacia MIC90 32.0 ug.mL-1 10.1128/aac.00248-09
Candida albicans Candida albicans MIC 20000.0 nM 10.6019/CHEMBL4513161
Candida albicans Candida albicans MIC nan None 10.1021/acs.jnatprod.6b00200
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Chlorocebus sabaeus Vero IC50 200.0 ug.mL-1 10.1021/acs.jmedchem.6b01805
Citrobacter amalonaticus Citrobacter amalonaticus MIC 8.0 ug.mL-1 10.1128/aac.01634-07
Citrobacter amalonaticus Citrobacter amalonaticus MIC 128.0 ug.mL-1 10.1021/jm900615h
Citrobacter amalonaticus Citrobacter amalonaticus MIC 512.0 ug.mL-1 10.1039/d2md00459c
Citrobacter freundii Citrobacter freundii Activity 99.0 % 10.1128/aac.00418-09
Citrobacter freundii Citrobacter freundii MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Citrobacter freundii Citrobacter freundii MIC 8.0 ug.mL-1 10.1128/aac.01634-07
Citrobacter freundii Citrobacter freundii MIC 64.0 ug.mL-1 10.1128/aac.01405-06
Citrobacter freundii Citrobacter freundii MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Citrobacter freundii Citrobacter freundii MIC90 0.5 ug.mL-1 10.1128/aac.00418-09
Citrobacter koseri Citrobacter koseri Activity nan None 10.1128/aac.00418-09
Citrobacter koseri Citrobacter koseri MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Citrobacter koseri Citrobacter koseri MIC 8.0 ug.mL-1 10.1128/aac.01634-07
Citrobacter koseri Citrobacter koseri MIC50 0.5 ug.mL-1 10.1128/aac.00418-09
Citrobacter koseri Citrobacter koseri MIC90 1.0 ug.mL-1 10.1128/aac.00418-09
Cronobacter sakazakii Cronobacter sakazakii MIC 16.0 ug.mL-1 10.1016/j.ejmech.2022.114495
Cryptococcus neoformans Cryptococcus neoformans MIC 20000.0 nM 10.6019/CHEMBL4513161
Enterobacter cloacae Enterobacter cloacae Activity 89.0 % 10.1128/aac.00675-09
Enterobacter cloacae Enterobacter cloacae Activity 100.0 % 10.1128/aac.00418-09
Enterobacter cloacae Enterobacter cloacae Activity 100.0 % 10.1128/aac.00675-09
Enterobacter cloacae Enterobacter cloacae MIC 0.047 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 0.12 ug.mL-1 10.1128/aac.00418-09
Enterobacter cloacae Enterobacter cloacae MIC 0.125 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 0.25 ug.mL-1 10.1021/jm00155a004
Enterobacter cloacae Enterobacter cloacae MIC 0.25 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 0.38 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 0.5 ug.mL-1 10.1021/jm00155a004
Enterobacter cloacae Enterobacter cloacae MIC 0.5 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1021/jm00155a004
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 1.5 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 2.0 ug.mL-1 10.1128/aac.01534-08
Enterobacter cloacae Enterobacter cloacae MIC 8.0 ug.mL-1 10.1128/aac.00931-08
Enterobacter cloacae Enterobacter cloacae MIC 8.0 ug.mL-1 10.1128/aac.01634-07
Enterobacter cloacae Enterobacter cloacae MIC 16.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Enterobacter cloacae Enterobacter cloacae MIC 16.0 ug.mL-1 10.1021/jm00155a004
Enterobacter cloacae Enterobacter cloacae MIC 16.0 ug.mL-1 10.1128/aac.01534-08
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.00726-07
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00882-08
Enterobacter cloacae Enterobacter cloacae MIC 512.0 ug.mL-1 10.1039/d2md00459c
Enterobacter cloacae Enterobacter cloacae MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Enterobacter cloacae Enterobacter cloacae MIC90 1.0 ug.mL-1 10.1128/aac.00418-09
Enterobacteriaceae Enterobacteriaceae Activity 8.5 % 10.1128/aac.00044-07
Enterobacteriaceae Enterobacteriaceae Activity 41.8 % 10.1128/aac.00044-07
Enterococcus Enterococcus MIC 128.0 ug.mL-1 10.1039/C2MD20162C
Enterococcus faecalis Enterococcus faecalis Activity nan None 10.1128/aac.00418-09
Enterococcus faecalis Enterococcus faecalis MIC 2.0 ug.mL-1 10.1128/aac.00418-09
Enterococcus faecalis Enterococcus faecalis MIC 8.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Enterococcus faecalis Enterococcus faecalis MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Enterococcus faecalis Enterococcus faecalis MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Enterococcus faecalis Enterococcus faecalis MIC 8.0 ug.mL-1 10.1039/D1MD00206F
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1016/j.bmcl.2004.05.004
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1016/j.bmcl.2005.02.029
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1016/j.bmcl.2005.08.032
Enterococcus faecalis Enterococcus faecalis MIC 62.5 ug.mL-1 10.1038/nature05756
Enterococcus faecalis Enterococcus faecalis MIC 128.0 ug.mL-1 10.1039/C2MD20162C
Enterococcus faecalis Enterococcus faecalis MIC 256.0 ug.mL-1 10.1021/acs.jnatprod.7b00565
Enterococcus faecalis Enterococcus faecalis MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
Enterococcus faecalis Enterococcus faecalis MIC80 nan None 10.1039/c9md00341j
Enterococcus faecalis Enterococcus faecalis MIC90 128.0 ug.mL-1 10.1128/aac.00418-09
Enterococcus faecium Enterococcus faecium Activity nan None 10.1128/aac.00418-09
Enterococcus faecium Enterococcus faecium MIC 2.0 ug.mL-1 10.1128/aac.00418-09
Enterococcus faecium Enterococcus faecium MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Enterococcus faecium Enterococcus faecium MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Enterococcus faecium Enterococcus faecium MIC 16.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Enterococcus faecium Enterococcus faecium MIC 16.0 ug.mL-1 10.1039/D1MD00206F
Enterococcus faecium Enterococcus faecium MIC 32.0 ug.mL-1 10.1016/j.ejmech.2022.114495
Enterococcus faecium Enterococcus faecium MIC 62.5 ug.mL-1 10.1038/nature05756
Enterococcus faecium Enterococcus faecium MIC 256.0 ug.mL-1 10.1021/acs.jnatprod.7b00565
Enterococcus faecium Enterococcus faecium MIC50 128.0 ug.mL-1 10.1128/aac.00418-09
Enterococcus faecium Enterococcus faecium MIC90 128.0 ug.mL-1 10.1128/aac.00418-09
Escherichia coli Escherichia coli Activity 22.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity 49.0 % 10.1128/aac.01338-09
Escherichia coli Escherichia coli Activity 50.0 % 10.1128/aac.00061-09
Escherichia coli Escherichia coli Activity 69.0 % 10.1128/aac.01338-09
Escherichia coli Escherichia coli Activity 93.0 % 10.1128/aac.01338-09
Escherichia coli Escherichia coli Activity 94.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity 95.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity 97.0 % 10.1128/aac.00675-09
Escherichia coli Escherichia coli Activity 100.0 % 10.1128/aac.00675-09
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00043-09
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00220-10
Escherichia coli Escherichia coli FC 760.0 None 10.1128/aac.00043-09
Escherichia coli Escherichia coli FC 3300.0 None 10.1128/aac.00043-09
Escherichia coli Escherichia coli IC50 15.0 nM 10.1021/jm400707f
Escherichia coli Escherichia coli INH 16.0 ug ml-1 10.1016/j.bmc.2019.115229
Escherichia coli Escherichia coli IZ 20.0 mm 10.1007/s00044-011-9911-y
Escherichia coli Escherichia coli MBC 64.3 mg/L 10.1007/s00044-011-9933-5
Escherichia coli Escherichia coli MBC 74.0 mg/L 10.1007/s00044-011-9933-5
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00926-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01345-06
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01360-08
Escherichia coli Escherichia coli MIC 0.13 ug.mL-1 10.1021/jm00155a004
Escherichia coli Escherichia coli MIC 0.13 ug.mL-1 10.1128/aac.00926-07
Escherichia coli Escherichia coli MIC 0.19 ug.mL-1 10.1128/aac.00882-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1016/j.bmcl.2017.06.022
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1021/jm00155a004
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00175-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00465-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00616-07
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00726-07
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00838-06
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01534-08
Escherichia coli Escherichia coli MIC 0.38 ug.mL-1 10.1128/aac.00810-07
Escherichia coli Escherichia coli MIC 0.38 ug.mL-1 10.1128/aac.00882-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.bmcl.2005.08.032
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.bmcl.2011.08.095
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.ejmech.2009.03.006
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.ejmech.2019.04.034
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.6b00867
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.6b01742
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1021/jm00155a004
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1021/jm401148j
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1021/jm900615h
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00795-06
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01137-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.bmcl.2004.05.004
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.bmcl.2005.02.029
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1021/jm00155a004
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1021/jm200506x
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00158-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01444-09
Escherichia coli Escherichia coli MIC 1.5 ug.mL-1 10.1128/aac.00043-09
Escherichia coli Escherichia coli MIC 1.95 ug.mL-1 10.1038/nature05756
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/acs.jnatprod.6b00200
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/jm200506x
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1039/D1MD00206F
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00043-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00465-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00896-08
Escherichia coli Escherichia coli MIC 2.5 ug.mL-1 10.1021/acs.jmedchem.7b00204
Escherichia coli Escherichia coli MIC 2.5 ug.mL-1 10.1021/jm200506x
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1016/j.bmcl.2015.10.087
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1128/aac.00882-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1021/jm00155a004
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00158-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00838-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01360-08
Escherichia coli Escherichia coli MIC 6.0 ug.mL-1 10.1128/aac.00810-07
Escherichia coli Escherichia coli MIC 6.0 ug.mL-1 10.1128/aac.01034-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.ejmech.2022.114278
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.ejmech.2022.114495
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.2c01469
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1021/jm00155a004
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00616-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00795-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00896-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01534-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01634-07
Escherichia coli Escherichia coli MIC 9.4 ug.mL-1 10.1021/jm400707f
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1021/jm00155a004
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00158-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00726-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01534-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.ejmech.2022.114495
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/jm401148j
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/jm900615h
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01444-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1021/jm401148j
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1021/jm900615h
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01345-06
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01444-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1021/jm900615h
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00926-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01137-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01320-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00560-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00882-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00926-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01320-07
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1039/d2md00459c
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00143-07
Escherichia coli Escherichia coli MIC 2500.0 nM 10.6019/CHEMBL4513161
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.01011-08
Escherichia coli Escherichia coli MIC50 1.07 mmol/ml 10.1016/j.ejmech.2010.02.023
Escherichia coli Escherichia coli MIC50 2.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC50 8.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC50 16.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC50 32.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC80 780.0 nM 10.1039/c9md00341j
Escherichia coli Escherichia coli MIC90 8.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1128/aac.00883-08
Haemophilus influenzae Haemophilus influenzae Activity nan None 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC 1.0 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Haemophilus influenzae Haemophilus influenzae MIC 4.7 ug.mL-1 10.1021/acsmedchemlett.5b00255
Haemophilus influenzae Haemophilus influenzae MIC 18.8 ug.mL-1 10.1021/jm400707f
Haemophilus influenzae Haemophilus influenzae MIC50 2.0 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC50 4.0 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Alpha-1d adrenergic receptor IC50 nan None None
Homo sapiens Alpha-1d adrenergic receptor Ki nan None None
Homo sapiens Alpha-2a adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2a adrenergic receptor Ki nan None None
Homo sapiens Alpha-2b adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2b adrenergic receptor Ki nan None None
Homo sapiens Alpha-2c adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2c adrenergic receptor Ki nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bile salt export pump IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Canalicular multispecific organic anion transporter 2 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 3A4 IC50 nan None None
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens Dopamine D1 receptor IC50 nan None None
Homo sapiens Dopamine D1 receptor Ki nan None None
Homo sapiens Dopamine D2 receptor IC50 nan None None
Homo sapiens Dopamine D2 receptor Ki nan None None
Homo sapiens Dopamine D3 receptor IC50 nan None None
Homo sapiens Dopamine D3 receptor Ki nan None None
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens dsDNA Kd 18000.0 nM 10.1016/j.bmcl.2022.128886
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens HEK293 CC50 20000.0 nM 10.6019/CHEMBL4513161
Homo sapiens HeLa Activity nan None 10.1128/aac.00729-05
Homo sapiens HERG IC50 nan None None
Homo sapiens HERG Ki nan None None
Homo sapiens Histamine H1 receptor IC50 nan None None
Homo sapiens Histamine H1 receptor Ki nan None None
Homo sapiens Histamine H2 receptor IC50 nan None None
Homo sapiens Histamine H2 receptor Ki nan None None
Homo sapiens Histone deacetylase 6 Inhibition -7.53 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition -5.82 % 10.6019/CHEMBL4808148
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens CL 0.98 mL.min-1.kg-1 None
Homo sapiens Homo sapiens CL 1.6 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL_renal 1.19 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens Cmax 9839.15 nM None
Homo sapiens Homo sapiens Cmax 11122.52 nM None
Homo sapiens Homo sapiens Excretion 90.0 % None
Homo sapiens Homo sapiens F 9.0 % None
Homo sapiens Homo sapiens T1/2 2.2 hr None
Homo sapiens Homo sapiens T1/2 145.0 hr None
Homo sapiens Homo sapiens Tmax 0.3 hr None
Homo sapiens Homo sapiens Vdss 0.33 L.kg-1 None
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens Menin Activity nan None 10.1016/j.bmcl.2014.03.055
Homo sapiens Menin Tm 41.43 degrees C 10.1016/j.bmcl.2014.03.055
Homo sapiens Menin Tm 42.61 degrees C 10.1016/j.bmcl.2014.03.055
Homo sapiens Menin Tm 43.35 degrees C 10.1016/j.bmcl.2014.03.055
Homo sapiens MG-63 Activity nan None 10.1128/aac.00729-05
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Multidrug resistance-associated protein 4 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki nan None None
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor IC50 nan None None
Homo sapiens Neurokinin 2 receptor Ki nan None None
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Norepinephrine transporter IC50 nan None None
Homo sapiens Norepinephrine transporter Ki nan None None
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki nan None None
Homo sapiens Serotonin transporter IC50 nan None None
Homo sapiens Serotonin transporter Ki nan None None
Homo sapiens Sigma opioid receptor IC50 nan None None
Homo sapiens Sigma opioid receptor Ki nan None None
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition 197.1 % 10.1124/mol.112.084152
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition 105.18 % 10.1124/mol.112.084152
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Tyrosine-protein kinase FYN IC50 nan None None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 REV Kd 4110.0 nM 10.1016/s0960-894x(01)00149-4
Klebsiella aerogenes Klebsiella aerogenes Activity 100.0 % 10.1128/aac.00418-09
Klebsiella aerogenes Klebsiella aerogenes MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Klebsiella aerogenes Klebsiella aerogenes MIC 128.0 ug.mL-1 10.1021/jm900615h
Klebsiella aerogenes Klebsiella aerogenes MIC 512.0 ug.mL-1 10.1039/d2md00459c
Klebsiella aerogenes Klebsiella aerogenes MIC50 0.5 ug.mL-1 10.1128/aac.00418-09
Klebsiella aerogenes Klebsiella aerogenes MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Klebsiella oxytoca Klebsiella oxytoca Activity nan None 10.1128/aac.00418-09
Klebsiella oxytoca Klebsiella oxytoca MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Klebsiella oxytoca Klebsiella oxytoca MIC 8.0 ug.mL-1 10.1128/aac.01634-07
Klebsiella oxytoca Klebsiella oxytoca MIC50 0.5 ug.mL-1 10.1128/aac.00418-09
Klebsiella oxytoca Klebsiella oxytoca MIC90 1.0 ug.mL-1 10.1128/aac.00418-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 8.0 % 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 10.8 % 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 67.0 % 10.1128/aac.00675-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 76.5 % 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 83.0 % 10.1128/aac.00675-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 92.0 % 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 96.0 % 10.1128/aac.00675-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 100.0 % 10.1128/aac.00418-09
Klebsiella pneumoniae Klebsiella pneumoniae MBC 24.1 mg/L 10.1007/s00044-011-9933-5
Klebsiella pneumoniae Klebsiella pneumoniae MBC 28.1 mg/L 10.1007/s00044-011-9933-5
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.06 ug.mL-1 10.1021/jm00155a004
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.00418-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.00715-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1016/j.bmcl.2017.06.022
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1016/j.ejmech.2019.04.034
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00867
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b01742
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.00715-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.bmcl.2005.08.032
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.bmcl.2017.06.022
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.ejmech.2009.03.006
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2011.08.095
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2017.06.022
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1021/jm401148j
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1021/jm900615h
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1016/j.ejmech.2022.114495
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01634-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1016/j.ejmech.2022.114278
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1021/acs.jmedchem.2c01469
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00158-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00726-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01534-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01672-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00882-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1039/d2md00459c
Klebsiella pneumoniae Klebsiella pneumoniae MIC 20000.0 nM 10.6019/CHEMBL4513161
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 2.14 mmol/ml 10.1016/j.ejmech.2010.02.023
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 16.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 32.0 ug.mL-1 10.1128/aac.00556-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 32.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC80 13000.0 nM 10.1039/c9md00341j
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00418-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.00556-09
Legionella pneumophila Legionella pneumophila Activity nan None 10.1128/aac.00418-09
Legionella pneumophila Legionella pneumophila MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Legionella pneumophila Legionella pneumophila MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Legionella pneumophila Legionella pneumophila MIC90 1.0 ug.mL-1 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes Activity nan None 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes IZ 20.0 mm 10.1007/s00044-011-9911-y
Listeria monocytogenes Listeria monocytogenes MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes MIC 2.3 ug.mL-1 10.1021/acsmedchemlett.5b00255
Listeria monocytogenes Listeria monocytogenes MIC 18.8 ug.mL-1 10.1021/jm400707f
Listeria monocytogenes Listeria monocytogenes MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes MIC90 0.12 ug.mL-1 10.1128/aac.00418-09
Moraxella catarrhalis Moraxella catarrhalis Activity 100.0 % 10.1128/aac.00418-09
Moraxella catarrhalis Moraxella catarrhalis MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Moraxella catarrhalis Moraxella catarrhalis MIC50 0.03 ug.mL-1 10.1128/aac.00418-09
Moraxella catarrhalis Moraxella catarrhalis MIC90 0.03 ug.mL-1 10.1128/aac.00418-09
Morganella morganii Morganella morganii Activity 100.0 % 10.1128/aac.00675-09
Morganella morganii Morganella morganii Activity nan None 10.1128/aac.00418-09
Morganella morganii Morganella morganii MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Morganella morganii Morganella morganii MIC 4.0 ug.mL-1 10.1128/aac.01634-07
Morganella morganii Morganella morganii MIC 8.0 ug.mL-1 10.1128/aac.01634-07
Morganella morganii Morganella morganii MIC50 1.0 ug.mL-1 10.1128/aac.00418-09
Morganella morganii Morganella morganii MIC90 4.0 ug.mL-1 10.1128/aac.00418-09
Mus musculus J774 Activity 83.2 % 10.1016/j.ejmech.2018.08.022
Mus musculus J774 Activity 99.7 % 10.1016/j.ejmech.2018.08.022
Mus musculus Monoamine oxidase A Activity nan None 10.1021/jm800656v
Mus musculus Monoamine oxidase B Activity nan None 10.1021/jm800656v
Mus musculus Mus musculus Activity 83.2 % 10.1021/acs.jmedchem.6b00818
Mus musculus Mus musculus Activity 99.7 % 10.1021/acs.jmedchem.6b00818
Mus musculus Mus musculus AUC 273.83 ng.hr.mL-1 10.1128/aac.01172-09
Mus musculus Mus musculus AUC 315.67 ng.hr.mL-1 10.1128/aac.01172-09
Mus musculus Mus musculus AUC 7061.33 ng.hr.mL-1 10.1128/aac.01172-09
Mus musculus Mus musculus AUC 7296.67 ng.hr.mL-1 10.1128/aac.01172-09
Mus musculus Mus musculus AUC 10978.17 ng.hr.mL-1 10.1128/aac.01172-09
Mus musculus Mus musculus AUC 11117.0 ng.hr.mL-1 10.1128/aac.01172-09
Mus musculus Mus musculus AUC 11382.17 ng.hr.mL-1 10.1128/aac.01172-09
Mus musculus Mus musculus AUC 11457.83 ng.hr.mL-1 10.1128/aac.01172-09
Mus musculus Mus musculus Cmax 705.85 nM 10.1128/aac.01172-09
Mus musculus Mus musculus Cmax 16683.78 nM 10.1128/aac.01172-09
Mus musculus Mus musculus Cmax 35207.05 nM 10.1128/aac.01172-09
Mus musculus Mus musculus Cmax 75419.23 nM 10.1128/aac.01172-09
Mus musculus Mus musculus F 0.48 % 10.1128/aac.01172-09
Mus musculus Mus musculus F 12.4 % 10.1128/aac.01172-09
Mus musculus Mus musculus F 96.45 % 10.1128/aac.01172-09
Mus musculus Mus musculus F 100.0 % 10.1128/aac.01172-09
Mus musculus Mus musculus fAUC 42960.0 ng.hr.mL-1 10.1128/aac.00174-07
Mus musculus Mus musculus fc max 19.07 mg/L 10.1128/aac.00174-07
Mus musculus Mus musculus MTD 60.0 mg Kg-1 10.1128/aac.00268-09
Mus musculus Mus musculus T1/2 0.295 hr 10.1128/aac.01172-09
Mus musculus Mus musculus T1/2 0.3388 hr 10.1128/aac.01172-09
Mus musculus Mus musculus T1/2 0.3662 hr 10.1128/aac.01172-09
Mus musculus Mus musculus T1/2 0.55 hr 10.1128/aac.00174-07
Mus musculus Mus musculus T1/2 0.6935 hr 10.1128/aac.01172-09
Mus musculus Mus musculus Tmax 0.08333 hr 10.1128/aac.01172-09
Mus musculus Mus musculus Tmax 0.25 hr 10.1128/aac.01172-09
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Mycobacterium leprae Mycobacterium leprae Activity 28.7 % 10.1016/j.bmc.2019.04.032
Mycobacterium leprae Mycobacterium leprae Activity 37.0 % 10.1016/j.bmc.2019.04.032
Mycobacteroides abscessus Mycobacteroides abscessus MIC 4.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides abscessus Mycobacteroides abscessus MIC 8.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides abscessus Mycobacteroides abscessus MIC 16.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides abscessus Mycobacteroides abscessus MIC 32.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides abscessus Mycobacteroides abscessus MIC 128.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides abscessus Mycobacteroides abscessus MIC50 8.0 ug.mL-1 10.1128/aac.00695-08
Mycobacteroides abscessus Mycobacteroides abscessus MIC50 8.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides abscessus Mycobacteroides abscessus MIC90 16.0 ug.mL-1 10.1128/aac.00695-08
Mycobacteroides abscessus Mycobacteroides abscessus MIC90 16.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides chelonae Mycobacteroides chelonae MIC 25.0 ug.mL-1 10.1128/aac.00590-09
Mycobacteroides chelonae Mycobacteroides chelonae MIC nan None 10.1128/aac.00590-09
Mycobacteroides chelonae Mycobacteroides chelonae MIC50 4.0 ug.mL-1 10.1128/aac.00695-08
Mycobacteroides chelonae Mycobacteroides chelonae MIC50 16.0 ug.mL-1 10.1128/aac.01551-06
Mycobacteroides chelonae Mycobacteroides chelonae MIC90 16.0 ug.mL-1 10.1128/aac.00695-08
Mycobacteroides chelonae Mycobacteroides chelonae MIC90 32.0 ug.mL-1 10.1128/aac.01551-06
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC 32.0 ug.mL-1 10.1016/s0960-894x(01)00283-9
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC 64.0 ug.mL-1 10.1128/aac.01551-06
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC 128.0 ug.mL-1 10.1128/aac.01551-06
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC50 16.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC50 16.0 ug.mL-1 10.1128/aac.01551-06
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC90 32.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC90 64.0 ug.mL-1 10.1128/aac.01551-06
Mycolicibacterium mageritense Mycolicibacterium mageritense MIC 8.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium peregrinum Mycolicibacterium peregrinum MIC50 4.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium peregrinum Mycolicibacterium peregrinum MIC90 8.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 0.03 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 0.6 ug.mL-1 10.1021/jm400707f
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 128.0 ug.mL-1 10.1021/acsmedchemlett.5b00255
Nocardia farcinica Nocardia farcinica MIC 32.0 ug.mL-1 10.1128/aac.00021-10
Nocardia farcinica Nocardia farcinica MIC 64.0 ug.mL-1 10.1128/aac.00021-10
Nocardia farcinica Nocardia farcinica MIC 1024.0 ug.mL-1 10.1128/aac.00021-10
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Proteus mirabilis Proteus mirabilis Activity 0.0 % 10.1128/aac.00675-09
Proteus mirabilis Proteus mirabilis Activity 100.0 % 10.1128/aac.00418-09
Proteus mirabilis Proteus mirabilis MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Proteus mirabilis Proteus mirabilis MIC 0.5 ug.mL-1 10.1021/jm00155a004
Proteus mirabilis Proteus mirabilis MIC 0.5 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC 4.0 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC50 1.0 ug.mL-1 10.1128/aac.00418-09
Proteus mirabilis Proteus mirabilis MIC50 8.0 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC90 4.0 ug.mL-1 10.1128/aac.00418-09
Proteus mirabilis Proteus mirabilis MIC90 32.0 ug.mL-1 10.1128/aac.00883-08
Proteus vulgaris Proteus vulgaris Activity 100.0 % 10.1128/aac.00418-09
Proteus vulgaris Proteus vulgaris MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Proteus vulgaris Proteus vulgaris MIC50 1.0 ug.mL-1 10.1128/aac.00418-09
Proteus vulgaris Proteus vulgaris MIC90 4.0 ug.mL-1 10.1128/aac.00418-09
Providencia rettgeri Providencia rettgeri MIC 0.13 ug.mL-1 10.1021/jm00155a004
Providencia rettgeri Providencia rettgeri MIC 32.0 ug.mL-1 10.1021/jm00155a004
Providencia stuartii Providencia stuartii MIC 2.0 ug.mL-1 10.1021/jm00155a004
Providencia stuartii Providencia stuartii MIC 16.0 ug.mL-1 10.1021/jm00155a004
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 0.4 None 10.1128/aac.01037-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 0.78 None 10.1128/aac.01037-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 1.36 None 10.1128/aac.01037-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 1.51 None 10.1128/aac.01037-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 2.0 % 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 2.0 log10CFU/ml 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 2.7 log10CFU/ml 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 3.0 log10CFU/ml 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 3.7 log10CFU/ml 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 4.0 log10CFU/ml 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 4.64 log10CFU/ml 10.1021/acs.jmedchem.2c01604
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 9.0 % 10.1128/aac.00810-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 20.0 mg.min/L 10.1128/aac.00054-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 21.7 % 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 30.0 mg.min/L 10.1128/aac.00054-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 33.9 % 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 36.9 % 10.1128/aac.00851-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 44.0 % 10.1128/aac.00810-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 44.8 % 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 55.0 % 10.1128/aac.01483-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 60.0 % 10.1128/aac.00268-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 67.5 % 10.1128/aac.00851-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 70.0 % 10.1128/aac.00054-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 77.5 % 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 83.8 % 10.1128/aac.00851-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 95.2 % 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 1000.0 mg.min/L 10.1128/aac.00054-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 250000.0 CFU/ml 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1016/j.ejmech.2021.113797
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1021/acs.jmedchem.6b01903
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1021/acs.jmedchem.9b00481
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1021/acs.jmedchem.9b00876
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1039/C5MD00373C
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1128/aac.00054-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1128/aac.01278-06
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1128/aac.01602-08
Pseudomonas aeruginosa Pseudomonas aeruginosa BBC 1.0 ug ml-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa BBC 2.0 ug ml-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa BBC 8.0 ug ml-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 0.2 None 10.1128/aac.00054-07
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 0.9 None 10.1128/aac.00054-07
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 1.0 None 10.1021/acs.jmedchem.1c00888
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 1.5 None 10.1128/aac.00054-07
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 2.0 None 10.1021/acs.jmedchem.1c00888
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 2.0 None 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 4.0 None 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 4.0 None 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa FC 16.0 None 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa FIC 0.125 None 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa FIC 0.25 None 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa FIC 0.5 None 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa FICI 1.0 None 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa FICI 1.125 None 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa FICI 1.25 None 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa FICI 1.5 None 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa FICI 4.81 None 10.1128/aac.01071-07
Pseudomonas aeruginosa Pseudomonas aeruginosa f %t > MIC nan None 10.1128/aac.00174-07
Pseudomonas aeruginosa Pseudomonas aeruginosa GI 100.0 % 10.1016/j.bmc.2013.09.019
Pseudomonas aeruginosa Pseudomonas aeruginosa INH 4.0 ug ml-1 10.1016/j.bmc.2019.115229
Pseudomonas aeruginosa Pseudomonas aeruginosa Inhibition 92.0 % 10.1021/acs.jmedchem.1c01241
Pseudomonas aeruginosa Pseudomonas aeruginosa Inhibition nan % 10.1016/j.bmc.2019.115229
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 18.0 mm 10.1007/s00044-011-9911-y
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 20.0 mm 10.1128/aac.01212-07
Pseudomonas aeruginosa Pseudomonas aeruginosa log10cfu 1.69 None 10.1128/aac.00237-08
Pseudomonas aeruginosa Pseudomonas aeruginosa log10cfu 2.48 None 10.1128/aac.00237-08
Pseudomonas aeruginosa Pseudomonas aeruginosa log10cfu 2.9 None 10.1128/aac.00268-09
Pseudomonas aeruginosa Pseudomonas aeruginosa log(activity) 0.5 None 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa log(activity) 1.0 None 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa log(activity) 1.5 None 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa log(activity) 2.0 None 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa log(activity) 2.5 None 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa log(activity) 3.0 None 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa log(activity) 4110000.0 None 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 13.7 mg/L 10.1007/s00044-011-9933-5
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 26.5 mg/L 10.1007/s00044-011-9933-5
Pseudomonas aeruginosa Pseudomonas aeruginosa MBIC50 2.0 uM 10.1021/acs.jmedchem.1c01241
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.06 ug.mL-1 10.1021/jm00155a004
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.06 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.12 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.12 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.12 ug.mL-1 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.12 ug.mL-1 10.1128/aac.01107-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.125 ug.mL-1 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.125 ug.mL-1 10.1039/C5MD00373C
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.125 ug.mL-1 10.1128/aac.00282-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.125 ug.mL-1 10.1128/aac.00912-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.13 ug.mL-1 10.1021/jm00155a004
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.19 ug.mL-1 10.1128/aac.01264-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.2 ug.mL-1 10.1128/aac.00419-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1016/j.bmcl.2005.02.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1016/j.bmcl.2017.06.022
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1016/j.ejmech.2018.08.022
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00818
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.7b00156
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1021/jm900615h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.00268-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.00893-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.01107-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.01264-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.38 ug.mL-1 10.1128/aac.01264-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.4 ug.mL-1 10.1128/aac.00419-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1016/j.bmcl.2004.05.004
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1016/j.bmcl.2005.02.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1016/j.bmcl.2017.06.022
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1016/j.ejmech.2018.08.022
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1016/j.ejmech.2022.114278
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.2c01469
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.6b00818
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1021/jm401148j
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1021/jm900615h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1039/C5MD00373C
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1039/D1MD00206F
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00268-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00282-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00912-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.01107-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.01264-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.6 ug.mL-1 10.1021/acsmedchemlett.5b00255
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.62 ug.mL-1 10.1038/nature05756
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.75 ug.mL-1 10.1128/aac.00282-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.75 ug.mL-1 10.1128/aac.00810-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.75 ug.mL-1 10.1128/aac.01264-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.9 ug.mL-1 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2005.02.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2011.08.095
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2020.127575
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b00793
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b01903
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/jm401148j
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/jm900615h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1039/C5MD00373C
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00080-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00174-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00237-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00415-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00822-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00893-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.00900-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.01034-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.01107-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.01212-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.01264-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.06 ug.mL-1 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.19 ug.mL-1 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.25 ug.mL-1 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.37 ug.mL-1 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.5 ug.mL-1 10.1128/aac.00282-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.5 ug.mL-1 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.5 ug.mL-1 10.1128/aac.00762-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.5 ug.mL-1 10.1128/aac.01264-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.75 ug.mL-1 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.bmcl.2005.02.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.bmcl.2017.06.022
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.ejmech.2020.112252
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1039/C5MD00373C
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00282-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00762-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00893-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.01212-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.01264-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.01573-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.2 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 3.0 ug.mL-1 10.1128/aac.00282-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 3.5 ug.mL-1 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 3.75 ug.mL-1 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1016/j.bmcl.2005.08.032
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1016/j.bmcl.2020.127413
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.1c00888
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1021/jm00155a004
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1039/C5MD00373C
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.01483-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 5.0 ug.mL-1 10.1021/acs.jmedchem.1c01781
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 5.0 ug.mL-1 10.1021/jm200506x
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.0 ug.mL-1 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.3 ug.mL-1 10.1016/j.bmcl.2005.02.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1016/j.ejmech.2020.112252
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.1c00888
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1039/C5MD00373C
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00080-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00175-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00704-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00893-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00912-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 10.0 ug.mL-1 10.1021/acs.jmedchem.1c01781
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.0 ug.mL-1 10.1128/aac.00822-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1021/jm00155a004
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1039/C5MD00373C
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00080-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00282-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00465-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00900-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.01011-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 24.0 ug.mL-1 10.1128/aac.00282-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1016/j.bmcl.2005.02.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1016/j.ejmech.2022.114495
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1021/acs.jnatprod.0c01151
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1039/C5MD00373C
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00282-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00824-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.01360-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 48.0 ug.mL-1 10.1128/aac.00465-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 48.0 ug.mL-1 10.1128/aac.00822-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 50.0 ug.mL-1 10.1016/j.bmcl.2005.02.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 50.0 ug.mL-1 10.1128/aac.01071-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1016/j.bmcl.2004.05.004
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00282-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00810-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00822-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00834-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.01024-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 96.0 ug.mL-1 10.1128/aac.00282-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 100.0 ug.mL-1 10.1016/j.bmcl.2005.02.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 125.0 ug.mL-1 10.1021/jm00155a004
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/jm401148j
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/jm900615h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1039/C2MD20162C
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.00175-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.01405-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.01573-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 200.0 ug.mL-1 10.1016/j.bmcl.2005.02.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 240.0 ug.mL-1 10.1128/aac.01071-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.00299-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.00810-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.00900-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.01345-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.01573-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 700.0 nM 10.1021/acs.jmedchem.8b01093
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1024.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1250.0 nM 10.6019/CHEMBL4513161
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2000.0 nM 10.1021/acs.jmedchem.1c01241
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2048.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4096.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6400.0 nM 10.1016/j.bmc.2015.04.020
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 20000.0 nM 10.6019/CHEMBL4513161
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 1.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 1.0 ug.mL-1 10.1128/aac.00912-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 2.0 ug.mL-1 10.1021/acs.jmedchem.7b00377
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 2.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 2.0 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 2.0 ug.mL-1 10.1128/aac.00912-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 8.0 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 32.0 ug.mL-1 10.1128/aac.00912-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 128.0 ug.mL-1 10.1128/aac.00912-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC80 1600.0 nM 10.1039/c9md00341j
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 1.0 ug.mL-1 10.1021/acs.jnatprod.2c01125
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 2.0 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 4.0 ug.mL-1 10.1128/aac.00912-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 32.0 ug.mL-1 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 64.0 ug.mL-1 10.1128/aac.00503-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 64.0 ug.mL-1 10.1128/aac.00912-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 128.0 ug.mL-1 10.1021/acs.jmedchem.7b00377
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 128.0 ug.mL-1 10.1128/aac.00912-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 256.0 ug.mL-1 10.1128/aac.00912-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Mortality 60.0 % 10.1128/aac.00174-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Mortality 66.7 % 10.1128/aac.00174-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Ratio 33.0 None 10.1128/aac.00054-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Ratio 256.0 None 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa Ratio 256.0 None 10.1021/acs.jmedchem.7b00156
Pseudomonas aeruginosa Pseudomonas aeruginosa Ratio 512.0 None 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa Survival 0.0 % 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa Survival 20.0 % 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa TIME 0.4283 hr 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa TIME 0.4333 hr 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa TIME 0.455 hr 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa TIME 0.4617 hr 10.1128/aac.00428-08
Pseudomonas aeruginosa Pseudomonas aeruginosa TIME 0.5 hr 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa TIME 1.0 hr 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa TIME 2.0 hr 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa TIME 4.0 hr 10.1128/aac.00248-09
Pseudomonas aeruginosa Pseudomonas aeruginosa TIME 8.0 hr 10.1128/aac.00248-09
Pseudomonas putida Pseudomonas putida MIC 8.0 ug.mL-1 10.1128/aac.00931-08
Pseudomonas putida Pseudomonas putida MIC 16.0 ug.mL-1 10.1128/aac.00838-06
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1a adrenergic receptor Ki nan None None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1b adrenergic receptor Ki nan None None
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Rattus norvegicus ALB 34200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 35400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 35600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 36400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 36600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 37100.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 38800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 40500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 41700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 43500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 137.2 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 186.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 192.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 204.75 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 217.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 228.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 233.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 236.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 300.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 314.25 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 20.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 24.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 25.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 27.25 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 28.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 28.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 30.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 31.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 32.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 78.2 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 79.3 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 79.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 80.2 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 81.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 85.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 86.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 86.75 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 89.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 91.75 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.032 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.078 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.091 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.11 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.12 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.13 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.35 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.38 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.42 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.57 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.6 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.72 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.75 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.77 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.78 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 1.16 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.4 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 3.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 3.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 112.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 127.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 132.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 142.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 144.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 148.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 152.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 152.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 163.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 170.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 105.4 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 105.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 105.6 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 106.25 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 106.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 107.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 108.2 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 108.25 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 108.8 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 109.8 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 449.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 512.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 517.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 557.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 558.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 560.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 570.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 584.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 594.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 692.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 132.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 214.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 233.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 257.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 303.2 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 334.3 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 349.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 384.75 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 410.25 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 601.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 24000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 25000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 25750000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 29000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 4.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 4.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 5.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 5.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 5.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 5.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 6.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 6.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 7.4 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.06 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.11 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.12 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.14 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.42 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.6 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.62 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.68 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.7 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.86 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.92 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 1.01 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 1.28 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 1.32 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1092.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1130.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1182.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1217.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1244.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1254.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1272.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1287.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1472.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 45.66 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 45.74 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 45.98 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 46.26 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 46.27 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 47.35 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 47.53 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 47.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 47.97 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 138600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 147200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 149200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 151700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 152200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 153800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 155600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 156300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 156500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 83.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 84.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 103.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 105.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 106.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 123.1 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 145.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 185.75 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 195.25 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 267.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 8.25 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 10.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 12.25 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 12.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 13.25 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 17.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 22.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 24.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 33.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 6.63 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 7.97 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 8.04 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 9.91 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 11.02 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 13.53 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 81.3 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 81.34 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 82.08 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 83.34 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 84.78 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 85.08 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 85.22 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 86.55 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 86.77 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 87.65 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 18.0 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 19.07 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 19.08 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 19.22 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 19.76 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 20.04 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 20.27 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 20.3 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 20.48 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 21.18 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 302200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 320500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 321600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 322500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 326700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 328700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 329000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 329300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 330000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 333800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 57.9 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 58.02 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 58.56 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 59.4 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 60.02 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.38 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.53 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.25 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.45 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 66.15 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.14 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.18 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.21 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.27 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.4 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.38 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.52 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.57 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.68 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.76 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.93 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.05 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.34 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.46 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.62 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 9.38 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 9.53 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 10.35 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 10.36 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 10.74 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 12.97 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 13.77 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 14.14 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 14.9 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 0.92 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 0.97 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1.17 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1.56 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 2.01 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 2.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 83.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 98.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 100.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 102.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 105.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 114.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 118.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 120.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 124.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 135.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1248400.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1300900.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1322400.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1323800.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1334500.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1359250.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1436600.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1445500.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1523000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1786000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.48 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.52 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.65 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.68 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.8 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.88 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.26 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.34 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.57 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.58 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 58400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 60000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 62800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 63800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 64800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 65300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 66600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7260000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7290000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7450000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7480000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7610000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7690000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7740000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7910000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 8160000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 8210000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 147.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 148.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 149.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 149.2 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 149.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 150.8 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 151.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 151.2 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 152.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 152.3 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 9.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 9.4 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 9.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 9.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 10.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 12.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 15.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 18.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 19.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 6740.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 8110.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 8680.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 9340.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 9410.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 11690.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 11910.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 12190.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13610.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 16610.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 nan None None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki nan None None
Salmonella Salmonella MIC 3.0 ug.mL-1 10.1016/j.bmcl.2015.10.087
Salmonella enterica Salmonella enterica INH 8.0 ug ml-1 10.1016/j.bmc.2019.115229
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity nan None 10.1128/aac.00382-07
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium EC50 1.0 ug.mL-1 10.1128/aac.00382-07
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium EC50 19.0 ug.mL-1 10.1128/aac.00382-07
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium IZ 18.0 mm 10.1007/s00044-011-9911-y
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 4.0 ug.mL-1 10.1128/aac.00382-07
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 125.0 ug.mL-1 10.1128/aac.00382-07
Serratia marcescens Serratia marcescens Activity 100.0 % 10.1128/aac.00418-09
Serratia marcescens Serratia marcescens MIC 0.12 ug.mL-1 10.1128/aac.00418-09
Serratia marcescens Serratia marcescens MIC 2.0 ug.mL-1 10.1021/jm00155a004
Serratia marcescens Serratia marcescens MIC 8.0 ug.mL-1 10.1128/aac.01634-07
Serratia marcescens Serratia marcescens MIC50 0.5 ug.mL-1 10.1128/aac.00418-09
Serratia marcescens Serratia marcescens MIC90 1.0 ug.mL-1 10.1128/aac.00418-09
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 13.99 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -0.18 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 2.66 % 10.21203/rs.3.rs-23951/v1
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition index 0.06782 None 10.1101/2020.04.03.023846
Shigella sonnei Shigella sonnei MIC 16.0 ug.mL-1 10.1039/C2MD20162C
Shigella sonnei Shigella sonnei MIC 32.0 ug.mL-1 10.1039/C2MD20162C
Staphylococcus aureus Staphylococcus aureus Activity 27.3 % 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus Activity 68.4 % 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/jm0703183
Staphylococcus aureus Staphylococcus aureus FC 5.0 None 10.1021/jm200506x
Staphylococcus aureus Staphylococcus aureus IZ 19.0 mm 10.1007/s00044-011-9911-y
Staphylococcus aureus Staphylococcus aureus log10cfu 0.86 None 10.1128/aac.00237-08
Staphylococcus aureus Staphylococcus aureus log10cfu 2.0 None 10.1128/aac.00237-08
Staphylococcus aureus Staphylococcus aureus MBC 11.8 mg/L 10.1007/s00044-011-9933-5
Staphylococcus aureus Staphylococcus aureus MBC 17.3 mg/L 10.1007/s00044-011-9933-5
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1021/jm00155a004
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC 0.13 ug.mL-1 10.1021/jm00155a004
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1021/acs.jnatprod.6b00200
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2005.08.032
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2011.08.095
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2009.03.006
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2018.08.022
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00818
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00867
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b01742
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/acsmedchemlett.5b00255
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2004.05.004
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2016.12.060
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2018.08.022
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2019.04.034
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2022.114278
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.2c01469
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.6b00818
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/acsmedchemlett.5b00255
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1039/D1MD00206F
Staphylococcus aureus Staphylococcus aureus MIC 0.62 ug.mL-1 10.1038/nature05756
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2005.02.029
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2015.04.046
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2022.114495
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1021/acs.jnatprod.8b00382
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1021/jm200506x
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1021/ml5001118
Staphylococcus aureus Staphylococcus aureus MIC 1.25 ug.mL-1 10.1021/jm200506x
Staphylococcus aureus Staphylococcus aureus MIC 1.5 ug.mL-1 10.1016/j.bmcl.2015.10.087
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm200506x
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1039/D1MD00206F
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.00237-08
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.bmcl.2015.04.046
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.ejmech.2022.114495
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1021/jm00155a004
Staphylococcus aureus Staphylococcus aureus MIC 9.4 ug.mL-1 10.1021/jm400707f
Staphylococcus aureus Staphylococcus aureus MIC 15.62 ug.mL-1 10.1007/s00044-012-0419-x
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1021/jm00155a004
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1039/C2MD20162C
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.bmcl.2015.04.046
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1021/jm00155a004
Staphylococcus aureus Staphylococcus aureus MIC 37.5 ug.mL-1 10.1021/jm400707f
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2004.05.004
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2005.02.029
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.ejmech.2018.08.022
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.6b00818
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/acsmedchemlett.5b00255
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1039/C2MD20162C
Staphylococcus aureus Staphylococcus aureus MIC 2048.0 ug.mL-1 10.1128/aac.00209-07
Staphylococcus aureus Staphylococcus aureus MIC 20000.0 nM 10.6019/CHEMBL4513161
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1016/j.bmcl.2020.127413
Staphylococcus aureus Staphylococcus aureus MIC50 0.125 ug.mL-1 10.1128/aac.00248-09
Staphylococcus aureus Staphylococcus aureus MIC50 0.5 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC50 0.53 mmol/ml 10.1016/j.ejmech.2010.02.023
Staphylococcus aureus Staphylococcus aureus MIC50 1.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC50 128.0 ug.mL-1 10.1128/aac.00248-09
Staphylococcus aureus Staphylococcus aureus MIC80 nan None 10.1039/c9md00341j
Staphylococcus aureus Staphylococcus aureus MIC90 1.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1128/aac.00248-09
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC90 128.0 ug.mL-1 10.1128/aac.00248-09
Staphylococcus chromogenes Staphylococcus chromogenes MIC 2.0 ug.mL-1 10.1016/j.ejmech.2022.114495
Staphylococcus epidermidis Staphylococcus epidermidis Activity 16.7 % 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 33.3 % 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis log10cfu 0.2 None 10.1128/aac.00237-08
Staphylococcus epidermidis Staphylococcus epidermidis log10cfu 3.08 None 10.1128/aac.00237-08
Staphylococcus epidermidis Staphylococcus epidermidis MBC 50.0 mg/L 10.1007/s00044-011-9933-5
Staphylococcus epidermidis Staphylococcus epidermidis MBIC 128.0 ug ml-1 10.1039/C2MD20162C
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.008 ug.mL-1 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.25 ug.mL-1 10.1016/j.ejmech.2019.04.034
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00867
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b01742
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.25 ug.mL-1 10.1128/aac.00237-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.3 ug.mL-1 10.1021/jm400707f
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.31 ug.mL-1 10.1038/nature05756
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1.0 ug.mL-1 10.1039/C2MD20162C
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Staphylococcus epidermidis Staphylococcus epidermidis MIC 8.0 ug.mL-1 10.1039/D1MD00206F
Staphylococcus epidermidis Staphylococcus epidermidis MIC 128.0 ug.mL-1 10.1039/C2MD20162C
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 0.03 ug.mL-1 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 2.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 nan None 10.1128/aac.00418-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 26.7 % 10.1128/aac.00418-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC50 2.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus hominis Staphylococcus hominis Activity 16.0 % 10.1128/aac.00418-09
Staphylococcus hominis Staphylococcus hominis MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Staphylococcus hominis Staphylococcus hominis MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus hominis Staphylococcus hominis MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus lugdunensis Staphylococcus lugdunensis Activity 46.7 % 10.1128/aac.00418-09
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus saprophyticus Staphylococcus saprophyticus Activity 54.5 % 10.1128/aac.00418-09
Staphylococcus saprophyticus Staphylococcus saprophyticus MBC 25.0 mg/L 10.1007/s00044-011-9933-5
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 0.008 ug.mL-1 10.1128/aac.00418-09
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC50 0.015 ug.mL-1 10.1128/aac.00418-09
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC90 0.06 ug.mL-1 10.1128/aac.00418-09
Staphylococcus warneri Staphylococcus warneri Activity 34.0 % 10.1128/aac.00418-09
Staphylococcus warneri Staphylococcus warneri MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Staphylococcus warneri Staphylococcus warneri MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Staphylococcus warneri Staphylococcus warneri MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 0.0 % 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 1.9 % 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 2.0 ug.mL-1 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 8.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 8.0 ug.mL-1 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 32.0 ug.mL-1 10.1128/aac.00795-06
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 512.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 512.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 512.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 8.0 ug.mL-1 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 32.0 ug.mL-1 10.1128/aac.00248-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 32.0 ug.mL-1 10.1128/aac.00248-09
Streptococcus agalactiae Streptococcus agalactiae Activity 73.0 % 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae MIC 32.0 ug.mL-1 10.1021/acs.jnatprod.8b00382
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus constellatus Streptococcus constellatus Activity 95.5 % 10.1128/aac.00418-09
Streptococcus constellatus Streptococcus constellatus MIC 0.008 ug.mL-1 10.1128/aac.00418-09
Streptococcus constellatus Streptococcus constellatus MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus constellatus Streptococcus constellatus MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus dysgalactiae Streptococcus dysgalactiae MIC 16.0 ug.mL-1 10.1016/j.ejmech.2022.114495
Streptococcus equinus Streptococcus equinus Activity 95.5 % 10.1128/aac.00418-09
Streptococcus equinus Streptococcus equinus MIC 0.008 ug.mL-1 10.1128/aac.00418-09
Streptococcus equinus Streptococcus equinus MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus equinus Streptococcus equinus MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius Activity 95.5 % 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius MIC 0.008 ug.mL-1 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis Activity 95.5 % 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis MIC 0.008 ug.mL-1 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus mutans Streptococcus mutans MBIC 64.0 ug ml-1 10.1039/C2MD20162C
Streptococcus mutans Streptococcus mutans MIC 128.0 ug.mL-1 10.1039/C2MD20162C
Streptococcus oralis Streptococcus oralis Activity 95.5 % 10.1128/aac.00418-09
Streptococcus oralis Streptococcus oralis MIC 0.008 ug.mL-1 10.1128/aac.00418-09
Streptococcus oralis Streptococcus oralis MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus oralis Streptococcus oralis MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1016/j.ejmech.2019.04.034
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes Activity 0.06 % 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes MIC 4.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes MIC 7.81 ug.mL-1 10.1007/s00044-012-0419-x
Streptococcus pyogenes Streptococcus pyogenes MIC 64.0 ug.mL-1 10.1021/jm400707f
Streptococcus pyogenes Streptococcus pyogenes MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus salivarius Streptococcus salivarius Activity 95.5 % 10.1128/aac.00418-09
Streptococcus salivarius Streptococcus salivarius MIC 0.008 ug.mL-1 10.1128/aac.00418-09
Streptococcus salivarius Streptococcus salivarius MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus salivarius Streptococcus salivarius MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis Activity 95.5 % 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis MIC 0.008 ug.mL-1 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus sp. Streptococcus sp. Activity 74.0 % 10.1128/aac.00418-09
Streptococcus sp. Streptococcus sp. MIC 0.008 ug.mL-1 10.1128/aac.00418-09
Streptococcus sp. Streptococcus sp. MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus sp. Streptococcus sp. MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
None ADMET C50 0.24 uM 10.1021/jm00385a015
None ADMET CL 1.6 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET K2 0.012 min-1 10.1016/S0960-894X(97)00339-9
None ADMET K2 0.051 min-1 10.1016/S0960-894X(97)00339-9
None ADMET K2 nan None 10.1016/S0960-894X(97)00339-9
None ADMET Kill at C50 54.0 % 10.1021/jm00385a015
None ADMET LD90 0.71 uM 10.1021/jm00385a015
None ADMET log10(%HIA +10) 1.0 None 10.1016/j.ejmech.2010.11.005
None ADMET MRT 2.4 hr 10.1124/dmd.108.020479
None ADMET T1/2 2.0 hr 10.1124/dmd.108.020479
None ADMET Uptake at C50 8.3 None 10.1021/jm00385a015
None ADMET Vdss 0.23 L.kg-1 10.1124/dmd.108.020479
None Erythrocyte HC10 20.0 uM 10.6019/CHEMBL4513161
None Hepatotoxicity Alkaline Phosphatase Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Number of Reports nan None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Active 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Marginal 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Number of Reports nan None 10.2174/1570163043334794
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx1000865
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity Hepatotoxicity nan None 10.1124/dmd.110.035113
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LDH Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Number of Reports nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Number of Reports nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Number of Reports nan None 10.2174/1570163043334794
None i-motif DNA Kd 13000.0 nM 10.1016/j.bmcl.2022.128886
None i-motif DNA Kd 17000.0 nM 10.1016/j.bmcl.2022.128886
None NON-PROTEIN TARGET Activity 56.0 % 10.1128/aac.01173-09
None NON-PROTEIN TARGET Activity 74.0 % 10.1128/aac.00418-09
None NON-PROTEIN TARGET Activity 95.5 % 10.1128/aac.00418-09
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00382-07
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00729-05
None NON-PROTEIN TARGET EC50 2.5 ug.mL-1 10.1128/aac.00382-07
None NON-PROTEIN TARGET EC50 75.0 ug.mL-1 10.1128/aac.00382-07
None NON-PROTEIN TARGET fAUC/MIC 43.0 None 10.1128/aac.00174-07
None NON-PROTEIN TARGET fc max/MIC 19.0 None 10.1128/aac.00174-07
None NON-PROTEIN TARGET Fu 1.0 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 0.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 12.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 23.5 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET MIC 0.008 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.00382-07
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.01634-07
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1016/j.bmc.2013.09.041
None NON-PROTEIN TARGET MIC 40.0 ug.mL-1 10.1021/jm200506x
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1039/C2MD20162C
None NON-PROTEIN TARGET MIC 250.0 ug.mL-1 10.1128/aac.00382-07
None NON-PROTEIN TARGET MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC50 32.0 ug.mL-1 10.1128/aac.00248-09
None NON-PROTEIN TARGET MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC90 32.0 ug.mL-1 10.1128/aac.00248-09
None NON-PROTEIN TARGET MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
None No relevant target Kd 0.9 nM 10.1021/jm030650o
None Nucleic Acid Frel 0.33 None 10.1016/j.bmcl.2005.02.007
None Nucleic Acid Kd 80.0 nM 10.1021/jm9000659
None Nucleic Acid Kd 430.0 nM 10.1016/s0960-894x(02)00342-6
None Nucleic Acid Kd 680.0 nM 10.1016/s0960-894x(01)00760-0
None Nucleic Acid Kd 1680.0 nM 10.1016/s0960-894x(00)00299-7
None Nucleic Acid Kd 2040.0 nM 10.1016/s0960-894x(01)00760-0
None Nucleic Acid Kd 2070.0 nM 10.1016/s0960-894x(01)00760-0
None Nucleic Acid Kd 2110.0 nM 10.1016/s0960-894x(00)00299-7
None Nucleic Acid Kd 2120.0 nM 10.1016/s0960-894x(01)00760-0
None Nucleic Acid Kd 2910.0 nM 10.1016/s0960-894x(02)00342-6
None Nucleic Acid Kd 3260.0 nM 10.1016/s0960-894x(02)00342-6
None Nucleic Acid Kd 5370.0 nM 10.1016/s0960-894x(02)00342-6
None Nucleic Acid Kd 100000.0 nM 10.1016/j.bmcl.2011.12.103
None Nucleic Acid Kd nan nM 10.1016/s0960-894x(01)00760-0
None Nucleic Acid MIC 10000.0 nM 10.1021/jm970372r
None Osteoblast Activity nan None 10.1128/aac.00729-05
None Phospholipidosis Phospholipidosis nan None 10.1021/ci6004542
None Phospholipidosis Phospholipidosis nan None 10.1021/mp100103e
None Phospholipidosis Phospholipidosis nan None 10.1080/15376510701857262
None Ribosomal RNA A-site IC50 70.0 nM 10.1021/acs.jmedchem.6b00793
None Ribosomal RNA A-site Kd 1500.0 nM 10.1016/s0960-894x(00)00615-6
None Unchecked Activity nan None 10.1128/aac.00382-07
None Unchecked Delta Tm 19.0 degrees C 10.1021/acs.jmedchem.7b01891
None Unchecked FICI 1.06 None 10.1021/acs.jmedchem.7b00156
None Unchecked Hepatotoxicity (acute) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 6.2 nM 10.1021/acs.jmedchem.6b00867
None Unchecked IC50 42320.0 nM 10.1021/acs.jmedchem.6b00793
None Unchecked IC50 nan None None
None Unchecked Inhibition 10.0 % 10.1016/j.ejmech.2019.112008
None Unchecked Kcat 16.6 /s 10.1128/aac.01444-09
None Unchecked Kcat 26.1 /s 10.1128/aac.01444-09
None Unchecked Kcat 26.7 /s 10.1128/aac.01444-09
None Unchecked Kcat/Km 1.7 10'7/M/s 10.1128/aac.01444-09
None Unchecked Kcat/Km 2.7 10'7/M/s 10.1128/aac.01444-09
None Unchecked Kd 1680.0 nM 10.1016/s0960-894x(01)00602-3
None Unchecked Ki 59900.0 nM 10.1016/j.bmcl.2014.03.055
None Unchecked Ki nan None None
None Unchecked Km 1000.0 nM 10.1128/aac.01444-09
None Unchecked Km 1500.0 nM 10.1128/aac.01444-09
None Unchecked Ratio IC50 604.57 None 10.1021/acs.jmedchem.6b00793

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT003108 CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>CC(=O)N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@@H]1[C@@H](N)C[C@@H](N)[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](N)[C@H]2O)[C@H]1O enzymemap_31528
AKRT004419 CC(=O)[32S].NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O>>CC(=O)NC1C(O)C(CO)O[C@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)[C@@H](O)C[C@H]3N)[C@@H]2O)C1O None
AKRT004420 CC(=O)[32S].NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O>>CC(=O)NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O None
AKRT004421 CC(=O)[32S].NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O>>CC(=O)N[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)[C@@H](O)C[C@H]3N)[C@@H]2O)O[C@H](CO)[C@H]1O None
AKRT004671 CC(=O)[CoA].NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>CC(=O)NC1C(O)C(CO)OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)CC3N)C2O)C1O MNXR130528
AKRT004672 CC(=O)[CoA].NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>CC(=O)NC1C(O)C(CO)O[C@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CN)[C@@H](O)C[C@H]3N)[C@@H](N)C[C@H]2N)C1O enzymemap_31554
AKRT004673 CC(=O)[CoA].NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>CC(=O)NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O enzymemap_32237
AKRT004674 CC(=O)[CoA].NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>CC(=O)N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@@H]1[C@@H](N)C[C@@H](N)[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](N)[C@H]2O)[C@H]1O enzymemap_31527
AKRT004675 CC(=O)[CoA].NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>CC(=O)N[C@H]1[C@H](O)[C@@H](CO)O[C@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CN)[C@@H](O)C[C@H]3N)[C@@H](N)C[C@H]2N)[C@@H]1O enzymemap_31538
AKRT007189 CCC(=O)[CoA].NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>CCC(=O)NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O enzymemap_32247
AKRT007190 CCC(=O)[CoA].NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>CCC(=O)N[C@H]1[C@H](O)[C@@H](CO)O[C@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CN)[C@@H](O)C[C@H]3N)[C@@H](N)C[C@H]2N)[C@@H]1O enzymemap_32201
AKRT007441 CCCC(=O)[CoA].NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>CCCC(=O)NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O enzymemap_32249
AKRT016484 N=c1[nH]c(=O)c2ncn([C@@H]3O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O)c2[nH]1.NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O>>N=c1[nH]c(=O)c2ncn([C@@H]3O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O)c2[nH]1.NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3OP(=O)(O)O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O None
AKRT017161 NC(=O)OP(=O)(O)O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](COC(N)=O)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O R10767
AKRT017164 NC(=O)OP(=O)(O)O.NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O>>NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COC(N)=O)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O RXN-15284
AKRT017177 NC(=O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O RXN-13168
AKRT017180 NC(=O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O.NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O>>NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COC(N)=O)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O RXN-13168
AKRT018488 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O)[C@H](N)C[C@@H]1O.N[C@H]1[C@H](O)[C@@H](CO)O[C@H](OP(=O)(O)OP(=O)(O)OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@H](O)[C@@H]2O)[C@@H]1O>>NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O R11278
AKRT018501 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O>>NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O enzymemap_48899
AKRT018502 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3OP(=O)(O)O)[C@H]2O)[C@H](N)C[C@@H]1O enzymemap_43937
AKRT018508 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O enzymemap_48899
AKRT018519 NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O.Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1>>NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3OP(=O)(O)O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O.Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1 None
AKRT018520 NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O>>NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3OP(=O)(O)O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O None
AKRT018521 NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O>>NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3OP(=O)(O)O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O RXN-16732
AKRT018531 NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COC(N)=O)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O>>NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O RXN-13168
AKRT022710 O=C(O)CC(=O)[CoA].NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O>>N[C@H]1[C@H](O)[C@@H](CO)O[C@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CNC(=O)CC(=O)O)[C@@H](O)C[C@H]3N)[C@@H](N)C[C@H]2N)[C@@H]1O enzymemap_32248