Salsolidine
AlkaPlorer ID: AK008449
Synonym: None
IUPAC Name: (1S)-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
Structure
SMILES: COC1=CC2=C(C=C1OC)[C@H](C)NCC2
InChI: InChI=1S/C12H17NO2/c1-8-10-7-12(15-3)11(14-2)6-9(10)4-5-13-8/h6-8,13H,4-5H2,1-3H3/t8-/m0/s1
InChIKey: HMYJLVDKPJHJCF-QMMMGPOBSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Salsola collina | Salsola | Chenopodiaceae | Caryophyllales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 207.273
TPSA？: 30.49
MolLogP？: 1.9105
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Electrophorus electricus | Acetylcholinesterase | Inhibition | -3.39 | % | 10.1016/j.bmc.2012.09.040 |
| Equus caballus | Cholinesterase | Inhibition | -4.57 | % | 10.1016/j.bmc.2012.09.040 |
| Homo sapiens | Cytochrome P450 1A2 | AC50 | nan | None | None |
| Homo sapiens | Cytochrome P450 2C19 | AC50 | nan | None | None |
| Homo sapiens | Cytochrome P450 2C9 | AC50 | nan | None | None |
| Homo sapiens | Cytochrome P450 2D6 | AC50 | nan | None | None |
| Homo sapiens | Cytochrome P450 3A4 | AC50 | nan | None | None |
| Homo sapiens | Histone acetyltransferase GCN5 | Potency | 11220.2 | nM | None |
| Homo sapiens | Solute carrier organic anion transporter family member 1B1 | Inhibition | 117.33 | % | 10.1124/mol.112.084152 |
| Homo sapiens | Solute carrier organic anion transporter family member 1B3 | Inhibition | 93.8 | % | 10.1124/mol.112.084152 |
| Homo sapiens | Thyroid stimulating hormone receptor | Potency | 15848.9 | nM | None |