2876-17-7
AlkaPlorer ID: AK008729
Synonym: None
IUPAC Name: 1-methoxyphenazine
Structure
SMILES: COC1=CC=CC2=NC3=CC=CC=C3N=C12
InChI: InChI=1S/C13H10N2O/c1-16-12-8-4-7-11-13(12)15-10-6-3-2-5-9(10)14-11/h2-8H,1H3
InChIKey: ZYDGCYWJDWIJCS-UHFFFAOYSA-N
Reference
7-Hydroxytropolon aus Pseudomonas sp. [1] / 7-Hydroxy Tropolone from Pseudomonas sp. [1]
PubChem CID: 76137
CAS: 2876-17-7
LOTUS: LTS0200179
SuperNatural Ⅲ: SN0483439
COCONUT: CNP0103979
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Pseudomonas chlororaphis | Pseudomonas | Pseudomonadaceae | Pseudomonadales | Gammaproteobacteria | Pseudomonadota | None | Bacteria |
Properties Information
Molecule Weight: 210.236
TPSA？: 35.010000000000005
MolLogP？: 2.7916000000000007
Number of H-Donors: 0
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | 786-0 | GI50 | 74131.02 | nM | None |
| Homo sapiens | A498 | GI50 | 76913.04 | nM | None |
| Homo sapiens | A549 | GI50 | 54200.09 | nM | None |
| Homo sapiens | ACHN | GI50 | 25292.98 | nM | None |
| Homo sapiens | CAKI-1 | GI50 | 60953.69 | nM | None |
| Homo sapiens | CCRF-CEM | GI50 | 43351.09 | nM | None |
| Homo sapiens | COLO 205 | GI50 | 90157.11 | nM | None |
| Homo sapiens | DU-145 | GI50 | 100000.0 | nM | None |
| Homo sapiens | EKVX | GI50 | 86696.19 | nM | None |
| Homo sapiens | HCC 2998 | GI50 | 79432.82 | nM | None |
| Homo sapiens | HCT-116 | GI50 | 38459.18 | nM | None |
| Homo sapiens | HCT-15 | GI50 | 39084.09 | nM | None |
| Homo sapiens | HL-60 | GI50 | 100000.0 | nM | None |
| Homo sapiens | HOP-62 | GI50 | 100000.0 | nM | None |
| Homo sapiens | HOP-92 | GI50 | 32960.97 | nM | None |
| Homo sapiens | Hs-578T | GI50 | 100000.0 | nM | None |
| Homo sapiens | HT-29 | GI50 | 46344.69 | nM | None |
| Homo sapiens | K562 | GI50 | 80167.81 | nM | None |
| Homo sapiens | KM12 | GI50 | 74131.02 | nM | None |
| Homo sapiens | LOX IMVI | GI50 | 38815.04 | nM | None |
| Homo sapiens | M14 | GI50 | 100000.0 | nM | None |
| Homo sapiens | Malme-3M | GI50 | 100000.0 | nM | None |
| Homo sapiens | MCF7 | GI50 | 54701.6 | nM | None |
| Homo sapiens | MDA-MB-231 | GI50 | 67608.3 | nM | None |
| Homo sapiens | MDA-MB-435 | GI50 | 100000.0 | nM | None |
| Homo sapiens | MDA-N | GI50 | 100000.0 | nM | None |
| Homo sapiens | MOLT-4 | GI50 | 60813.5 | nM | None |
| Homo sapiens | NCI/ADR-RES | GI50 | 100000.0 | nM | None |
| Homo sapiens | NCI-H226 | GI50 | 45498.81 | nM | None |
| Homo sapiens | NCI-H23 | GI50 | 100000.0 | nM | None |
| Homo sapiens | NCI-H322M | GI50 | 40179.08 | nM | None |
| Homo sapiens | NCI-H460 | GI50 | 39810.72 | nM | None |
| Homo sapiens | OVCAR-3 | GI50 | 90991.33 | nM | None |
| Homo sapiens | OVCAR-5 | GI50 | 100000.0 | nM | None |
| Homo sapiens | OVCAR-8 | GI50 | 23823.19 | nM | None |
| Homo sapiens | PC-3 | GI50 | 25527.01 | nM | None |
| Homo sapiens | Quinone reductase 2 | IC50 | 31100.0 | nM | 10.1021/jm1011066 |
| Homo sapiens | Quinone reductase 2 | Inhibition | 88.6 | % | 10.1021/jm1011066 |
| Homo sapiens | RPMI-8226 | GI50 | 17021.59 | nM | None |
| Homo sapiens | RXF 393 | GI50 | 39264.49 | nM | None |
| Homo sapiens | SF-268 | GI50 | 87902.25 | nM | None |
| Homo sapiens | SF-295 | GI50 | 79983.43 | nM | None |
| Homo sapiens | SF-539 | GI50 | 84527.88 | nM | None |
| Homo sapiens | SK-MEL-28 | GI50 | 100000.0 | nM | None |
| Homo sapiens | SK-MEL-5 | GI50 | 54827.7 | nM | None |
| Homo sapiens | SK-OV-3 | GI50 | 100000.0 | nM | None |
| Homo sapiens | SN12C | GI50 | 71449.63 | nM | None |
| Homo sapiens | SNB-19 | GI50 | 94623.72 | nM | None |
| Homo sapiens | SNB-75 | GI50 | 59979.11 | nM | None |
| Homo sapiens | SR | GI50 | 44055.49 | nM | None |
| Homo sapiens | SW-620 | GI50 | 45814.19 | nM | None |
| Homo sapiens | T47D | GI50 | 76032.63 | nM | None |
| Homo sapiens | TK-10 | GI50 | 66069.34 | nM | None |
| Homo sapiens | U-251 | GI50 | 55462.57 | nM | None |
| Homo sapiens | UACC-257 | GI50 | 91201.08 | nM | None |
| Homo sapiens | UACC-62 | GI50 | 50933.09 | nM | None |
| Homo sapiens | UO-31 | GI50 | 35974.93 | nM | None |
| Mus musculus | NAD(P)H dehydrogenase [quinone] 1 | Ratio | 1.4 | None | 10.1021/jm1011066 |
| Mus musculus | RAW264.7 | Inhibition | 2.4 | % | 10.1021/jm1011066 |
| None | Unchecked | Inhibition | 0.0 | % | 10.1021/jm1011066 |