1,6-dihydroxy-3,5-dimethoxy-10-methylacridin-9-one
AlkaPlorer ID: AK009429
Synonym: None
IUPAC Name: 1,6-dihydroxy-3,5-dimethoxy-10-methylacridin-9-one
Structure
SMILES: COC1=CC(O)=C2C(=O)C3=CC=C(O)C(OC)=C3N(C)C2=C1
InChI: InChI=1S/C16H15NO5/c1-17-10-6-8(21-2)7-12(19)13(10)15(20)9-4-5-11(18)16(22-3)14(9)17/h4-7,18-19H,1-3H3
InChIKey: OQMSMWRXIZYYNR-UHFFFAOYSA-N
Reference
Coumarins, acridone alkaloids and a flavone from Citrus grandis
PubChem CID: 5494827
LOTUS: LTS0071155
SuperNatural Ⅲ: SN0272572
COCONUT: CNP0155621
data_source: manually
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 301.298
TPSA？: 80.92000000000002
MolLogP？: 2.1200999999999994
Number of H-Donors: 2
Number of H-Acceptors: 6
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | A549 | IC50 | 40000.0 | nM | 10.1021/np980504z |
| Homo sapiens | CCRF-HSB-2 | IC50 | 40000.0 | nM | 10.1021/np980504z |
| Homo sapiens | TGBC11TKB | IC50 | 40000.0 | nM | 10.1021/np980504z |
| Mus musculus | B16 | IC50 | 40000.0 | nM | 10.1021/np980504z |