lauroyl vanillylamides
AlkaPlorer ID: AK009597
Synonym: 'Lauroyl vanillylamide'
IUPAC Name: N-[(4-hydroxy-3-methoxyphenyl)methyl]dodecanamide
Structure
SMILES: CCCCCCCCCCCC(=O)NCC1=CC=C(O)C(OC)=C1
InChI: InChI=1S/C20H33NO3/c1-3-4-5-6-7-8-9-10-11-12-20(23)21-16-17-13-14-18(22)19(15-17)24-2/h13-15,22H,3-12,16H2,1-2H3,(H,21,23)
InChIKey: QXOUXETZELPRMZ-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces mobaraensis | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 335.48800000000006
TPSA？: 58.56
MolLogP？: 4.937900000000005
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bos taurus | NADH-ubiquinone oxidoreductase chain 1 | IC50 | 6309.57 | nM | 10.1016/0005-2728(95)00131-x |
| Mus musculus | Mus musculus | Inhibition | 48.1 | % | 10.1021/jm00070a002 |
| Mus musculus | Mus musculus | Latency | 9.9 | None | 10.1021/jm00070a002 |
| Mus musculus | Mus musculus | Lethality | 25.0 | % | 10.1021/jm00070a002 |
| Mus musculus | Mus musculus | Lethality | 100.0 | % | 10.1021/jm00070a002 |
| Mus musculus | Mus musculus | Response | 0.0 | None | 10.1021/jm00070a002 |
| None | Unchecked | IC50 | 100000.0 | nM | 10.1016/0005-2728(95)00131-x |
| None | Unchecked | Inhibition | 70.0 | % | 10.1016/0005-2728(95)00131-x |
| None | Unchecked | Inhibition | nan | % | 10.1016/0005-2728(95)00131-x |
| None | Unchecked | pI50 | nan | None | 10.1016/0005-2728(95)00131-x |