Piriferine
AlkaPlorer ID: AK009691
Synonym: None
IUPAC Name: 2-methyl-N-[(2R)-1-[(E)-3-phenylprop-2-enoyl]pyrrolidin-2-yl]propanamide
Structure
SMILES: CC(C)C(O)=N[C@H]1CCCN1C(=O)/C=C/C1=CC=CC=C1
InChI: InChI=1S/C17H22N2O2/c1-13(2)17(21)18-15-9-6-12-19(15)16(20)11-10-14-7-4-3-5-8-14/h3-5,7-8,10-11,13,15H,6,9,12H2,1-2H3,(H,18,21)/b11-10+/t15-/m1/s1
InChIKey: MHTFRPKYOLEGDG-AUECHBEKSA-N
Reference
Piriferine, a New Pyrrolidine Alkaloid from Aglaia pirifera Leaves
PubChem CID: 9548036
LOTUS: LTS0180161
SuperNatural Ⅲ: SN0225978-04
NPASS: NPC143516
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Aglaia | Meliaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Aglaia elliptifolia | Aglaia | Meliaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 286.375
TPSA？: 52.900000000000006
MolLogP？: 3.2608000000000024
Number of H-Donors: 1
Number of H-Acceptors: 2
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | A-431 | ED50 | 20.0 | ug ml-1 | 10.1021/np50094a004 |
| Homo sapiens | HT-1080 | ED50 | 20.0 | ug ml-1 | 10.1021/np50094a004 |
| Homo sapiens | KB | ED50 | 20.0 | ug ml-1 | 10.1021/np50094a004 |
| Homo sapiens | LNCaP | ED50 | 20.0 | ug ml-1 | 10.1021/np50094a004 |
| Homo sapiens | SK-MEL-2 | ED50 | 20.0 | ug ml-1 | 10.1021/np50094a004 |
| Homo sapiens | ZR-75-1 | ED50 | 20.0 | ug ml-1 | 10.1021/np50094a004 |
| None | NON-PROTEIN TARGET | ED50 | 8.5 | ug ml-1 | 10.1021/np50094a004 |
| None | NON-PROTEIN TARGET | ED50 | 10.0 | ug ml-1 | 10.1021/np50094a004 |
| None | NON-PROTEIN TARGET | ED50 | 20.0 | ug ml-1 | 10.1021/np50094a004 |