Pratorimine
AlkaPlorer ID: AK009733
Synonym: ''
IUPAC Name: 5-hydroxy-4-methoxy-9-azatetracyclo[7.6.1.02,7.012,16]hexadeca-1(15),2,4,6,10,12(16),13-heptaen-8-one
Structure
SMILES: COC1=CC2=C(C=C1O)C(=O)N1C=CC3=CC=CC2=C31
InChI: InChI=1S/C16H11NO3/c1-20-14-8-11-10-4-2-3-9-5-6-17(15(9)10)16(19)12(11)7-13(14)18/h2-8,18H,1H3
InChIKey: LAKWSSVAGFQTAY-UHFFFAOYSA-N
Reference
Alkaloids from the Bulbs of Crinum bulbispermum.
PubChem CID: 181937
CAS: 88860-12-2
LOTUS: LTS0099296
SuperNatural Ⅲ: SN0200274
COCONUT: CNP0156153
data_source: manually
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Crinum americanum | Crinum | Amaryllidaceae | Asparagales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 265.26800000000003
TPSA？: 50.94
MolLogP？: 2.757900000000001
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | A2780 | IC50 | 75000.0 | nM | 10.1016/j.bmc.2017.06.017 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 38000.0 | nM | 10.1016/j.bmc.2017.06.017 |