2,4-Quinolinediol
AlkaPlorer ID: AK009976
Synonym: 4-Hydroxy-2(1H)-quinolinone, 4-Hydroxycarbostyril, 2,4-Dihydroxyquinoline, 2-Hydroxy-4(1H)-quinolinone, 2,4(1H,3H)-Quinolinedione
IUPAC Name: 4-hydroxy-1H-quinolin-2-one
Structure
SMILES: OC1=CC(O)=C2C=CC=CC2=N1
InChI: InChI=1S/C9H7NO2/c11-8-5-9(12)10-7-4-2-1-3-6(7)8/h1-5H,(H2,10,11,12)
InChIKey: HDHQZCHIXUUSMK-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Haplophyllum bucharicum | Haplophyllum | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 161.15999999999997
TPSA？: 53.35
MolLogP？: 1.6459999999999992
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Aldehyde dehydrogenase 1A1 | Potency | 5011.9 | nM | None |
| Homo sapiens | Geminin | Potency | 8199.5 | nM | None |
| Homo sapiens | Guanine nucleotide-binding protein G(s), subunit alpha | Potency | 3981.1 | nM | None |
| Homo sapiens | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Potency | 79432.8 | nM | None |
| Homo sapiens | Lysine-specific demethylase 4D-like | Potency | 39810.7 | nM | None |
| Mycobacterium tuberculosis | Mycobacterium tuberculosis | Inhibition | 0.0 | % | 10.1016/j.bmcl.2006.09.082 |
| Trichophyton benhamiae | Trichophyton benhamiae | MIC | 500000000.0 | nM | 10.1016/j.bmcl.2006.09.082 |
| None | Unchecked | Potency | 206.0 | nM | None |