Schizozygine
AlkaPlorer ID: AK010180
Synonym: None
IUPAC Name: (1S,14S,18S,19R)-8,10-dioxa-4,17-diazaheptacyclo[15.4.3.01,18.04,19.05,13.07,11.014,19]tetracosa-5,7(11),12,22-tetraen-3-one
Structure
SMILES: O=C1C[C@]23C=CCN4CC[C@H]5C6=CC7=C(C=C6N1[C@@]5(CC2)[C@@H]43)OCO7
InChI: InChI=1S/C20H20N2O3/c23-17-10-19-3-1-6-21-7-2-13-12-8-15-16(25-11-24-15)9-14(12)22(17)20(13,5-4-19)18(19)21/h1,3,8-9,13,18H,2,4-7,10-11H2/t13-,18-,19-,20+/m0/s1
InChIKey: DTBOGXTYLFTPCH-XCXWGBRNSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Schizozygia | Apocynaceae | Gentianales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 336.39100000000013
TPSA？: 42.010000000000005
MolLogP？: 2.4123
Number of H-Donors: 0
Number of H-Acceptors: 4
RingCount: 7
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |
| Candida albicans | Candida albicans | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |
| Cladosporium cladosporioides | Cladosporium cladosporioides | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |
| Cladosporium herbarum | Cladosporium herbarum | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |
| Epidermophyton floccosum | Epidermophyton floccosum | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |
| Escherichia coli | Escherichia coli | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |
| Human immunodeficiency virus 1 | Human immunodeficiency virus type 1 reverse transcriptase | IC50 | 200.0 | ug.mL-1 | 10.1021/np50073a012 |
| Nannizzia gypsea | Nannizzia gypsea | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |
| Trichophyton interdigitale | Trichophyton interdigitale | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |
| Trichophyton mentagrophytes | Trichophyton mentagrophytes | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |
| Trichophyton tonsurans | Trichophyton tonsurans | MIC | 500.0 | ug.mL-1 | 10.1021/np010298m |