Navigation

name Structure Reference Source Properties Activities Metabolism

Papaveraldine

AlkaPlorer ID: AK010274

Synonym: 'SMR001223913', 'MLS001360484', 'Xanthaline'

IUPAC Name: (6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)methanone

Structure

SMILES: COC1=CC=C(C(=O)C2=NC=CC3=CC(OC)=C(OC)C=C23)C=C1OC

copy

InChI: InChI=1S/C20H19NO5/c1-23-15-6-5-13(10-16(15)24-2)20(22)19-14-11-18(26-4)17(25-3)9-12(14)7-8-21-19/h5-11H,1-4H3

copy

InChIKey: QJTBIAMBPGGIGI-UHFFFAOYSA-N

copy

Source

Species Genus Family Order Class Phylum Kingdom Domain
Papaver somniferum Papaver Papaveraceae Ranunculales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 353.37400000000014

TPSA？: 66.88000000000001

MolLogP？: 3.500200000000002

Number of H-Donors: 0

Number of H-Acceptors: 6

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Electrophorus electricus Acetylcholinesterase Inhibition 2.3 % 10.1007/s00044-008-9122-3
Homo sapiens Acetylcholinesterase Inhibition 2.3 % 10.1016/j.bmcl.2006.01.067
Homo sapiens Acetylcholinesterase Inhibition 38.6 % 10.1016/j.bmcl.2006.01.067
Homo sapiens Apoptotic protease-activating factor 1 IC50 24400.0 nM None
Homo sapiens Apoptotic protease-activating factor 1 IC50 100000.0 nM None
Homo sapiens Ataxin-2 Potency 100.0 nM None
Homo sapiens ATPase family AAA domain-containing protein 5 Potency 29081.0 nM None
Homo sapiens Caspase-3 IC50 8210.0 nM None
Homo sapiens DNA polymerase eta Potency 63095.7 nM None
Homo sapiens DNA polymerase iota Potency 56234.1 nM None
Homo sapiens Glucagon-like peptide 1 receptor Potency 1778.3 nM None
Homo sapiens Guanine nucleotide-binding protein G(s), subunit alpha Potency 31622.8 nM None
Homo sapiens Histone-lysine N-methyltransferase NSD2 AC50 6770.0 nM None
Homo sapiens Lethal(3)malignant brain tumor-like protein 1 Potency 39810.7 nM None
Homo sapiens Sentrin-specific protease 6 IC50 805.0 nM None
Homo sapiens Sentrin-specific protease 7 IC50 1670.0 nM None
Homo sapiens Sentrin-specific protease 8 IC50 2470.0 nM None
Homo sapiens Sentrin-specific protease 8 IC50 5000.0 nM None
Homo sapiens Serine/threonine-protein phosphatase IC50 19597.0 nM None
Homo sapiens Serine/threonine protein phosphatase PP1-alpha catalytic subunit IC50 67047.0 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 18356.4 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 29092.9 nM None
Homo sapiens Ubiquitin carboxyl-terminal hydrolase 1 Potency 14125.4 nM None
Plasmodium falciparum Plasmodium falciparum Potency 737.5 nM None
Plasmodium falciparum Plasmodium falciparum Potency 1168.9 nM None
Schistosoma mansoni Thioredoxin glutathione reductase Potency 50118.7 nM None
None Unchecked IC50 4770.0 nM None
None Unchecked Potency 1258.9 nM None

Metabolism Information