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cyclo(L-Leu-L-Pro)

AlkaPlorer ID: AK010659

Synonym: '', 'cyclo (L)-Pro-(L)-Leu', 'cyclo-(Pro-Leu)', 'cyclo(Leu-Pro)', 'Cyclo(leucylprolyl)', 'Cyclo(D)-Pro-(D)-Leu', 'Gancidin W', '32510-93-3', 'Cyclo(pro-leu)', 'Cyclo-L-leu-L-pro', 'cyclo(L-prolyl-L-leucyl)', 'cycloL-Leucyl-L-Prolyl', 'L-cyclo(Leu-pro)', '43041-29-8', 'cyclo(L-leucyl-L-prolyl)', 'cycloL-leucyl-L-prolyl', 'Maculosin 6', '19943-30-7', 'cyclo(Pro-Leu)', '36238-67-2', 'L,L-Cyclo(leucylprolyl)', 'L-Leucyl-L-proline lactam', '2873-36-1', 'L-cyclo(Leucyloprolyl)', 'cyclo(L-Pro-L-Leu)'

IUPAC Name: (3S,8aS)-3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Structure

SMILES: CC(C)C[C@@H]1N=C(O)[C@@H]2CCCN2C1=O

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InChI: InChI=1S/C11H18N2O2/c1-7(2)6-8-11(15)13-5-3-4-9(13)10(14)12-8/h7-9H,3-6H2,1-2H3,(H,12,14)/t8-,9-/m0/s1

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InChIKey: SZJNCZMRZAUNQT-IUCAKERBSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Achromobacter xylosoxidans Achromobacter Alcaligenaceae Burkholderiales Betaproteobacteria Pseudomonadota None Bacteria
Ulva pertusa Ulva Ulvaceae Ulvales Ulvophyceae Chlorophyta Viridiplantae Eukaryota
Callyspongia pseudoreticulata Callyspongia Callyspongiidae Haplosclerida Demospongiae Porifera Metazoa Eukaryota
Bacillus amyloliquefaciens Bacillus Bacillaceae Bacillales Bacilli Bacillota None Bacteria
Eschweilera coriacea Eschweilera Lecythidaceae Ericales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Pseudomonas aeruginosa Pseudomonas Pseudomonadaceae Pseudomonadales Gammaproteobacteria Pseudomonadota None Bacteria
Sanguisorba tenuifolia Sanguisorba Rosaceae Rosales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Uvaria tanzaniae Uvaria Annonaceae Magnoliales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Amansia glomerata Amansia Rhodomelaceae Ceramiales Florideophyceae Rhodophyta None Eukaryota
Turbo stenogyrus Turbo Turbinidae Trochida Gastropoda Mollusca Metazoa Eukaryota
Uvaria hamiltonii Uvaria Annonaceae Magnoliales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Lobophora papenfussii Lobophora Dictyotaceae Dictyotales Phaeophyceae None None Eukaryota
Senecio serra Senecio Asteraceae Asterales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Salvadora persica Salvadora Salvadoraceae Brassicales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Eucalyptus cladocalyx Eucalyptus Myrtaceae Myrtales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Entada abyssinica Entada Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Aspergillus violaceus Aspergillus Aspergillaceae Eurotiales Eurotiomycetes Ascomycota Fungi Eukaryota
Portulaca oleracea Portulaca Portulacaceae Caryophyllales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 210.277

TPSA？: 52.900000000000006

MolLogP？: 1.3622

Number of H-Donors: 1

Number of H-Acceptors: 2

RingCount: 2

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bacillus cereus Bacillus cereus Activity nan None 10.1021/np960095b
Bacillus subtilis Bacillus subtilis MIC 15.7 ug.mL-1 10.1016/j.bmcl.2015.06.010
Dengue virus Dengue virus EC50 11200.0 nM 10.1016/j.ejmech.2019.05.010
Enterococcus faecalis Enterococcus faecalis MIC 12.5 ug.mL-1 10.1016/j.bmc.2018.11.042
Escherichia coli Escherichia coli MIC 20.0 ug.mL-1 10.1016/j.bmcl.2015.06.010
Fusobacterium nucleatum Fusobacterium nucleatum Inhibition nan % 10.1016/j.bmc.2018.11.042
Homo sapiens Neurokinin 1 receptor Activity nan None 10.1021/np50106a005
Micrococcus luteus Micrococcus luteus Activity nan None 10.1021/np960095b
Mus musculus Mus musculus Inhibition nan % 10.1021/jm00194a009
Porphyromonas gingivalis Porphyromonas gingivalis Inhibition nan % 10.1016/j.bmc.2018.11.042
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/np960095b
Staphylococcus aureus Staphylococcus aureus MIC 18.8 ug.mL-1 10.1016/j.bmcl.2015.06.010
Streptococcus mutans Streptococcus mutans GI nan None 10.1016/j.bmc.2018.11.042
Streptococcus mutans Streptococcus mutans Inhibition nan % 10.1016/j.bmc.2018.11.042
None NON-PROTEIN TARGET IC50 1100000.0 nM 10.1016/j.bmc.2012.01.050
None NON-PROTEIN TARGET Inhibition 0.0 % 10.1016/j.bmc.2012.01.050
None NON-PROTEIN TARGET Inhibition 86.2 % 10.1016/j.bmc.2012.01.050

Metabolism Information