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Cyclosporin A

AlkaPlorer ID: AK010808

Synonym: None

IUPAC Name: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone

Structure

SMILES: C/C=C/C[C@@H](C)[C@@H](O)[C@H]1C(O)=N[C@@H](CC)C(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(O)=N[C@@H](C(C)C)C(=O)N(C)[C@@H](CC(C)C)C(O)=N[C@@H](C)C(O)=N[C@H](C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N1C

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InChI: InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1

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InChIKey: PMATZTZNYRCHOR-CGLBZJNRSA-N

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Properties Information

Molecule Weight: 1202.634999999999

TPSA？: 292.76

MolLogP？: 6.630200000000022

Number of H-Donors: 5

Number of H-Acceptors: 12

RingCount: 1

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Bovine viral diarrhea virus 1 Bovine viral diarrhea virus 1 IC50 9900.0 nM 10.1128/aac.01324-07
Canis lupus familiaris MDCK logPapp -5.16 None 10.1021/jm901846t
Canis lupus familiaris MDCK Papp 1.1 ucm/s 10.1021/acs.jmedchem.5b00128
Canis lupus familiaris MDCK TC50 9.9 uM 10.1128/aac.01324-07
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Cavia porcellus Voltage-dependent L-type calcium channel subunit alpha-1C IC50 2000.0 nM 10.1002/jat.2784
Chlorocebus sabaeus Vero Activity nan None 10.1128/aac.00189-09
Chlorocebus sabaeus Vero CC50 50000.0 nM 10.1101/2020.03.20.999730
Chlorocebus sabaeus Vero TC50 16.6 uM 10.1128/aac.01324-07
Chlorocebus sabaeus Vero C1008 CC50 26300.0 nM 10.6019/CHEMBL4651402
Chlorocebus sabaeus Vero C1008 pCC50 4.58 None 10.6019/CHEMBL4651402
Coxsackievirus Coxsackievirus IC50 25000.0 nM 10.1128/aac.01324-07
Cryptococcus neoformans Cryptococcus neoformans MIC 0.39 ug.mL-1 10.1021/acs.jmedchem.7b01413
dengue virus type 1 dengue virus type 1 IC50 500.0 nM 10.1128/aac.00189-09
dengue virus type 1 dengue virus type 1 Inhibition 70.0 % 10.1128/aac.00189-09
dengue virus type 1 dengue virus type 1 Inhibition nan % 10.1128/aac.00189-09
dengue virus type 2 dengue virus type 2 Activity nan None 10.1128/aac.00189-09
Electrophorus electricus Acetylcholinesterase Inhibition -12.0 % 10.1016/j.bmc.2012.09.040
Enterovirus A71 Enterovirus A71 EC50 3660.0 nM 10.1016/j.bmcl.2015.11.002
Equus caballus Cholinesterase Inhibition -5.62 % 10.1016/j.bmc.2012.09.040
Feline coronavirus Feline coronavirus IC50 1500.0 nM 10.1128/aac.01324-07
Gallus gallus Gallus gallus ED50 50.0 nM 10.1021/jm980307x
Hepacivirus hominis Hepatitis C virus Activity nan None 10.1039/C1MD00227A
Hepacivirus hominis Hepatitis C virus CC50 5620.0 nM 10.1128/aac.00660-09
Hepacivirus hominis Hepatitis C virus EC50 4.0 nM 10.1128/aac.00939-08
Hepacivirus hominis Hepatitis C virus EC50 137.0 nM 10.1039/C1MD00227A
Hepacivirus hominis Hepatitis C virus EC50 170.0 nM 10.1021/acs.jmedchem.6b01329
Hepacivirus hominis Hepatitis C virus EC50 198.0 nM 10.1039/C1MD00227A
Hepacivirus hominis Hepatitis C virus EC50 210.0 nM 10.1128/aac.01236-09
Hepacivirus hominis Hepatitis C virus EC50 230.0 nM 10.1016/j.bmcl.2013.05.101
Hepacivirus hominis Hepatitis C virus EC50 240.0 nM 10.1128/aac.01534-07
Hepacivirus hominis Hepatitis C virus EC50 300.0 nM 10.1128/aac.01534-07
Hepacivirus hominis Hepatitis C virus EC50 306.0 nM 10.1039/C1MD00227A
Hepacivirus hominis Hepatitis C virus EC50 350.0 nM 10.1128/aac.00939-08
Hepacivirus hominis Hepatitis C virus EC50 370.0 nM 10.1016/j.bmcl.2010.09.036
Hepacivirus hominis Hepatitis C virus EC50 400.0 nM 10.1128/aac.00939-08
Hepacivirus hominis Hepatitis C virus EC50 455.0 nM 10.1039/C1MD00227A
Hepacivirus hominis Hepatitis C virus EC50 490.0 nM 10.1128/aac.00939-08
Hepacivirus hominis Hepatitis C virus EC50 500.0 nM 10.1128/aac.01534-07
Hepacivirus hominis Hepatitis C virus EC50 773.0 nM 10.1021/acs.jmedchem.8b00802
Hepacivirus hominis Hepatitis C virus EC50 1980.0 nM 10.1128/aac.00939-08
Hepacivirus hominis Hepatitis C virus EC50 3390.0 nM 10.1128/aac.01236-09
Hepacivirus hominis Hepatitis C virus EC50 3850.0 nM 10.1128/aac.00939-08
Hepacivirus hominis Hepatitis C virus EC50 10000.0 nM 10.1128/aac.01236-09
Hepacivirus hominis Hepatitis C virus EC90 910.0 nM 10.1016/j.bmcl.2010.09.036
Hepacivirus hominis Hepatitis C virus EC90 1000.0 nM 10.1039/C1MD00227A
Hepacivirus hominis Hepatitis C virus IC50 2300.0 nM 10.1128/aac.01324-07
Hepatitis B virus Hepatitis B virus IC50 200.0 nM 10.1021/acs.jmedchem.6b01442
Hepatitis B virus Hepatitis B virus IC50 400.0 nM 10.1016/j.bmc.2022.116862
Hepatitis B virus Hepatitis B virus IC50 5784.0 nM 10.1021/acs.jmedchem.0c01484
Hepatitis B virus Hepatitis B virus IC50 nan None 10.1128/aac.01324-07
Hepatitis B virus Hepatitis B virus Inhibition 83.0 % 10.1016/j.bmc.2022.116862
Homo sapiens A2780 Activity 10.0 % 10.1021/ml1002663
Homo sapiens A2780 GI50 8940.0 nM 10.1016/j.ejmech.2016.03.067
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens Adenosine A1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Alpha-1a adrenergic receptor AC50 2826.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1d adrenergic receptor IC50 nan None None
Homo sapiens Alpha-1d adrenergic receptor Ki nan None None
Homo sapiens Alpha-2a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2a adrenergic receptor Ki nan None None
Homo sapiens Alpha-2b adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2b adrenergic receptor Ki nan None None
Homo sapiens Alpha-2c adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2c adrenergic receptor Ki nan None None
Homo sapiens Androgen Receptor Potency 4466.8 nM None
Homo sapiens Androgen Receptor Potency 14125.4 nM None
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens Ataxin-2 Potency 8912.5 nM None
Homo sapiens ATPase family AAA domain-containing protein 5 Potency 8196.1 nM None
Homo sapiens ATP-binding cassette sub-family G member 2 Activity nan None 10.1021/jm901826e
Homo sapiens ATP-binding cassette sub-family G member 2 EC50 1750.0 nM 10.1021/acs.jmedchem.9b00963
Homo sapiens ATP-binding cassette sub-family G member 2 EC50 nan None 10.1021/acs.jmedchem.9b00963
Homo sapiens ATP-binding cassette sub-family G member 2 IC50 4300.0 nM 10.1016/j.ejmech.2022.114346
Homo sapiens ATP-binding cassette sub-family G member 2 IC50 6568.0 nM 10.1021/acs.jmedchem.0c01826
Homo sapiens ATP-binding cassette sub-family G member 2 IC50 63095.73 nM 10.1016/j.bmc.2008.07.034
Homo sapiens ATP-binding cassette sub-family G member 2 Ki 500.0 nM 10.1006/bbrc.2001.5130
Homo sapiens Beta-1 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-3 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bile acid receptor FXR AC50 6699.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile acid receptor FXR AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile acid transporter IC50 1000.0 nM None
Homo sapiens Bile salt export pump AC50 1052.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump Activity nan None 10.1038/nrd3028
Homo sapiens Bile salt export pump IC50 400.0 nM 10.1002/hep.27206
Homo sapiens Bile salt export pump IC50 400.0 nM 10.1021/acs.jmedchem.0c00524
Homo sapiens Bile salt export pump IC50 500.0 nM 10.1093/toxsci/kft176
Homo sapiens Bile salt export pump IC50 500.0 nM 10.1124/dmd.111.040758
Homo sapiens Bile salt export pump IC50 900.0 nM 10.1093/toxsci/kfq269
Homo sapiens Bile salt export pump IC50 7500.0 nM 10.1023/a:1023278211849
Homo sapiens Bile salt export pump IC50 7800.0 nM 10.1023/a:1023278211849
Homo sapiens Bile salt export pump IC50 10000.0 nM 10.1124/dmd.112.047068
Homo sapiens Bile salt export pump Inhibition nan % 10.1124/dmd.112.044891
Homo sapiens Bile salt export pump Ki 9500.0 nM 10.1053/gast.2002.36591
Homo sapiens Blood AUC 170.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood AUC 266.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood AUC 334.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood AUC 569.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood AUC 812.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood AUC 853.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood AUC 2232.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood AUC 2553.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood AUC 5509.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood AUC 6467.0 ng.hr.mL-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood AUC 9399.0 ng.hr.mL-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood AUC 9485.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood AUC 9939.0 ng.hr.mL-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood AUC 11479.0 ng.hr.mL-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood CL 4.333 mL.min-1.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood CL 4.667 mL.min-1.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood CL 5.5 mL.min-1.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood CL 5.667 mL.min-1.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood CL 5.933 mL.min-1.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood CL 6.0 mL.min-1.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood CL 6.6 mL.min-1.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood CL 7.833 mL.min-1.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Cmax 20.79 nM 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Cmax 36.59 nM 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Cmax 353.39 nM 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood Cmax 773.31 nM 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood Cmax 794.09 nM 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood Cmax 800.75 nM 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Cmax 827.35 nM 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Cmax 1255.58 nM 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood F 23.0 % 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood F 23.0 % 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood F 24.0 % 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood F 28.0 % 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood F 33.0 % 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood F 42.0 % 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood MAT 2.59 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood MAT 3.69 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood MAT 5.48 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood MRT 3.52 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood MRT 3.87 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood MRT 4.35 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Ratio 1.1 None 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood Ratio 1.18 None 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood Ratio 1.29 None 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood Ratio 2.56 None 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood Ratio AUC 0.018 None 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Ratio AUC 0.037 None 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Ratio AUC 0.047 None 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Ratio AUC 0.063 None 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Ratio AUC 0.081 None 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Ratio AUC 0.14 None 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Ratio AUC 0.18 None 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Ratio AUC 0.24 None 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Ratio AUC 0.41 None 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Ratio AUC 0.68 None 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood T1/2 0.41 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood T1/2 5.68 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Tmax 3.3 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Tmax 5.3 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Vd 0.373 L.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood Vd 0.466 L.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood Vdss 1.2 L.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Vdss 1.23 L.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood Vdss 1.3 L.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Vdss 1.53 L.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Blood Vdss 3.2 L.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Blood Vdss 188.0 L.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Bradykinin B1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens Breast cancer cell line EC50 500.0 nM 10.1021/jm010126m
Homo sapiens Breast cancer cell line EC50 600.0 nM 10.1021/jm010126m
Homo sapiens Breast cancer cell line Ratio 1.4 None 10.1021/jm010126m
Homo sapiens Breast cancer cell line Ratio 1.7 None 10.1021/jm010126m
Homo sapiens Breast cancer cell line Relative potency 32.5 None 10.1021/jm010126m
Homo sapiens Breast cancer cell line Relative potency 41.9 None 10.1021/jm010126m
Homo sapiens Breast cancer cell line Relative resistance 1.3 None 10.1021/jm010126m
Homo sapiens Caco-2 logPapp -6.0 None 10.1016/j.bmc.2011.03.011
Homo sapiens Caco-2 Papp 15.9 nm/s 10.1016/j.bmc.2007.09.039
Homo sapiens Caco-2 Papp 15.9 nm/s 10.1016/j.bmc.2008.01.055
Homo sapiens Caco-2 Papp 153.0 nm/s 10.1016/j.bmc.2007.09.039
Homo sapiens Caco-2 Papp 153.0 nm/s 10.1016/j.bmc.2008.01.055
Homo sapiens Caco-2 Ratio 9.6 None 10.1016/j.bmc.2007.09.039
Homo sapiens Caco-2 Ratio 9.6 None 10.1016/j.bmc.2008.01.055
Homo sapiens Caco-2 Ratio 9.6 None 10.1021/jm701267q
Homo sapiens Calcineurin B alpha IC50 34000.0 nM 10.1021/acs.jnatprod.1c00118
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Canalicular multispecific organic anion transporter 1 Activity 40.0 % 10.1021/jm7015683
Homo sapiens Canalicular multispecific organic anion transporter 1 Activity nan None 10.1016/j.bbrc.2003.09.007
Homo sapiens Canalicular multispecific organic anion transporter 1 Activity nan None 10.1038/nrd3028
Homo sapiens Canalicular multispecific organic anion transporter 1 Activity nan None 10.1124/mol.56.6.1219
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 13600.0 nM 10.1016/j.bmcl.2008.07.127
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 14500.0 nM 10.1093/toxsci/kft176
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 16270.0 nM 10.1021/acs.jmedchem.0c01826
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 20000.0 nM 10.1016/j.ejmech.2016.06.039
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 25600.0 nM 10.1016/j.ejmech.2016.06.039
Homo sapiens Canalicular multispecific organic anion transporter 1 Inhibition nan % 10.1016/j.ejmech.2016.06.039
Homo sapiens Canalicular multispecific organic anion transporter 1 Inhibition nan % 10.1039/C1MD00227A
Homo sapiens Canalicular multispecific organic anion transporter 1 Ki 4700.0 nM 10.1124/mol.56.6.1219
Homo sapiens Canalicular multispecific organic anion transporter 1 Ki 8110.0 nM 10.1023/a:1016192413308
Homo sapiens Canalicular multispecific organic anion transporter 1 Ki 21000.0 nM 10.1002/hep.510300220
Homo sapiens Canalicular multispecific organic anion transporter 2 IC50 631.5 nM 10.1021/acs.jmedchem.0c01826
Homo sapiens Canalicular multispecific organic anion transporter 2 IC50 23000.0 nM 10.1093/toxsci/kft176
Homo sapiens Cannabinoid CB1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens Cholecystokinin A receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Cholecystokinin B receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Corticotropin releasing factor receptor 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Corticotropin releasing factor receptor 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cyclophilin A Activity nan None 10.1016/j.bmcl.2016.10.050
Homo sapiens Cyclophilin A IC50 2.0 nM 10.1016/j.bmcl.2003.09.042
Homo sapiens Cyclophilin A IC50 3.7 nM 10.1038/nchembio.214
Homo sapiens Cyclophilin A IC50 7.2 nM 10.1021/acs.jmedchem.5b01064
Homo sapiens Cyclophilin A IC50 8.33 nM 10.1016/j.bmcl.2010.09.036
Homo sapiens Cyclophilin A IC50 9.0 nM 10.1021/jm00048a002
Homo sapiens Cyclophilin A IC50 9.3 nM 10.1016/j.ejmech.2011.09.019
Homo sapiens Cyclophilin A IC50 9.6 nM 10.1039/C1MD00227A
Homo sapiens Cyclophilin A IC50 10.25 nM 10.1016/j.ejmech.2011.02.023
Homo sapiens Cyclophilin A IC50 23.0 nM 10.1016/j.bmcl.2015.11.002
Homo sapiens Cyclophilin A IC50 27.0 nM 10.1021/jm00017a020
Homo sapiens Cyclophilin A IC50 40.7 nM 10.1021/jm9008295
Homo sapiens Cyclophilin A IC50 62.0 nM 10.1021/jm00017a020
Homo sapiens Cyclophilin A IC50 100.0 nM 10.1038/nchembio.214
Homo sapiens Cyclophilin A IC50 950.0 nM 10.1039/C1MD00227A
Homo sapiens Cyclophilin A Inhibition 50.0 % 10.1128/aac.00660-09
Homo sapiens Cyclophilin A Inhibition nan % 10.1016/j.bmcl.2016.10.050
Homo sapiens Cyclophilin A Inhibition nan % 10.1128/aac.00660-09
Homo sapiens Cyclophilin A K 0.06759 /s 10.1016/j.bmcl.2016.10.050
Homo sapiens Cyclophilin A K 0.06895 /s 10.1016/j.bmcl.2016.10.050
Homo sapiens Cyclophilin A K 0.06916 /s 10.1016/j.bmcl.2016.10.050
Homo sapiens Cyclophilin A K 0.06941 /s 10.1016/j.bmcl.2016.10.050
Homo sapiens Cyclophilin A K 0.06953 /s 10.1016/j.bmcl.2016.10.050
Homo sapiens Cyclophilin A K 6.81 10'-2/s 10.1016/j.bmcl.2016.10.050
Homo sapiens Cyclophilin A Ka 1.3 10'8M 10.1016/j.ejmech.2011.09.019
Homo sapiens Cyclophilin A Ka 7.6 10'3/M/s 10.1021/acs.jmedchem.5b01064
Homo sapiens Cyclophilin A Kd 0.48 None 10.1021/jm9903139
Homo sapiens Cyclophilin A Kd 2.5 10'-2/s 10.1021/acs.jmedchem.5b01064
Homo sapiens Cyclophilin A Kd 6.0 nM 10.1021/acs.jmedchem.6b00411
Homo sapiens Cyclophilin A Kd 7.6 nM 10.1016/j.ejmech.2011.09.019
Homo sapiens Cyclophilin A Kd 9.0 nM 10.1038/nchembio.214
Homo sapiens Cyclophilin A Kd 10.0 nM 10.1016/j.bmcl.2016.09.039
Homo sapiens Cyclophilin A Kd 10.0 nM 10.1021/ml200039u
Homo sapiens Cyclophilin A Kd 17.0 nM 10.1021/acs.jmedchem.6b01329
Homo sapiens Cyclophilin A Kd 17.0 nM 10.1021/acs.jmedchem.8b00802
Homo sapiens Cyclophilin A Kd 36.8 nM 10.1016/j.bmcl.2008.06.006
Homo sapiens Cyclophilin A Kd 300.0 nM 10.1021/jm010009r
Homo sapiens Cyclophilin A Kd 6420.0 nM 10.1016/j.ejmech.2011.02.023
Homo sapiens Cyclophilin A Ki 2.64 nM 10.1128/aac.00660-09
Homo sapiens Cyclophilin A Ki 6.7 nM 10.1021/acs.jmedchem.6b01329
Homo sapiens Cyclophilin A Ki 7.0 nM 10.1021/acs.jmedchem.1c00211
Homo sapiens Cyclophilin A Ki 9.79 nM 10.1128/aac.01324-07
Homo sapiens Cyclophilin A Ki 12.2 nM 10.1021/jm4007577
Homo sapiens Cyclophilin A Ki 20.0 nM 10.1016/j.bmcl.2004.06.028
Homo sapiens Cyclophilin A Ki 227.0 nM 10.1021/ml1001272
Homo sapiens Cyclophilin A Ki 231.0 nM 10.1021/ml1001272
Homo sapiens Cyclophilin B IC50 8.78 nM 10.1016/j.bmcl.2010.09.036
Homo sapiens Cyclophilin B Ka 2.7 10'3/M/s 10.1021/acs.jmedchem.5b01064
Homo sapiens Cyclophilin B Kd 5.8 10'-3/s 10.1021/acs.jmedchem.5b01064
Homo sapiens Cyclophilin B Kd 9.8 nM 10.1016/j.bmcl.2008.06.006
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 1A2 IC50 100000.0 nM 10.1128/aac.00660-09
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2C19 IC50 7000.0 nM 10.1128/aac.00660-09
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C9 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 2C9 IC50 38800.0 nM 10.1128/aac.00660-09
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 2D6 IC50 100000.0 nM 10.1128/aac.00660-09
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 3A IC50 1240.0 nM 10.1124/dmd.111.043018
Homo sapiens Cytochrome P450 3A IC50 1470.0 nM 10.1124/dmd.111.043018
Homo sapiens Cytochrome P450 3A Inhibition nan % 10.1124/dmd.111.043018
Homo sapiens Cytochrome P450 3A Ki 980.0 nM 10.1124/dmd.111.043018
Homo sapiens Cytochrome P450 3A4 Activity nan None None
Homo sapiens Cytochrome P450 3A4 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 3A4 IC50 1450.0 nM 10.1124/dmd.111.043018
Homo sapiens Cytochrome P450 3A4 IC50 2060.0 nM 10.1124/dmd.111.043018
Homo sapiens Cytochrome P450 3A4 IC50 6500.0 nM 10.1021/jm021012t
Homo sapiens Cytochrome P450 3A4 IC50 6600.0 nM 10.1128/aac.00660-09
Homo sapiens Cytochrome P450 3A4 IC50 10000.0 nM None
Homo sapiens Cytochrome P450 3A4 IC50 nan None None
Homo sapiens Cytochrome P450 3A4 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 3A4 Inhibition nan % 10.1124/dmd.111.043018
Homo sapiens Cytochrome P450 3A4 Ki 300.0 nM 10.1124/dmd.111.043018
Homo sapiens Cytochrome P450 3A4 Ki 890.0 nM 10.1124/dmd.111.043018
Homo sapiens Cytochrome P450 3A4 Ki 1420.0 nM 10.1016/j.bmc.2022.116862
Homo sapiens Cytochrome P450 3A4 Ki 7600.0 nM 10.1124/dmd.111.043018
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Cytochrome P450 3A4 Log 1/Km -0.6021 None 10.1016/j.bmcl.2005.06.015
Homo sapiens Cytochrome P450 3A5 Inhibition nan % 10.1124/dmd.111.043018
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens Dihydroorotate dehydrogenase IC50 50000.0 nM 10.1021/jm981028c
Homo sapiens DNA polymerase iota Potency 89125.1 nM None
Homo sapiens Dopamine D1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor IC50 nan None None
Homo sapiens Dopamine D1 receptor Ki nan None None
Homo sapiens Dopamine D2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor IC50 nan None None
Homo sapiens Dopamine D2 receptor Ki nan None None
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor IC50 nan None None
Homo sapiens Dopamine D3 receptor Ki nan None None
Homo sapiens Dopamine D4 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens Endothelin receptor ET-A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Endothelin receptor ET-B AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor alpha Potency 22387.2 nM None
Homo sapiens Estrogen receptor beta AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens Eyes absent homolog 2 Inhibition nan % None
Homo sapiens FK506-binding protein 1A Kd nan nM 10.1016/0960-894X(95)00404-H
Homo sapiens FK506-binding protein 1A Ki 20.0 nM 10.1021/jm980307x
Homo sapiens FK506-binding protein 1B Ki 6.0 nM 10.1021/jm00021a005
Homo sapiens FK506 binding protein 4 IC50 16.0 nM 10.1021/jm9903139
Homo sapiens Focal adhesion kinase 1 Activity nan None 10.1021/acs.jmedchem.8b01826
Homo sapiens Formyl peptide receptor 1 IC20 3.6 uM 10.1021/jm010987v
Homo sapiens Formyl peptide receptor 1 IC50 10000.0 nM 10.1021/jm010987v
Homo sapiens GABA-B receptor 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Gastric inhibitory polypeptide receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Geminin Potency 631.0 nM None
Homo sapiens Ghrelin receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucagon-like peptide 1 receptor Potency 2511.9 nM None
Homo sapiens Glucagon receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens H4 Activity 55.82 % 10.1073/pnas.0709695104
Homo sapiens H4 Activity 71.69 % 10.1073/pnas.0709695104
Homo sapiens H4 Activity 73.62 % 10.1073/pnas.0709695104
Homo sapiens H4 Activity 101.74 % 10.1073/pnas.0709695104
Homo sapiens H4 Activity 104.28 % 10.1073/pnas.0709695104
Homo sapiens H4 Activity 114.15 % 10.1073/pnas.0709695104
Homo sapiens H4 Activity 117.39 % 10.1073/pnas.0709695104
Homo sapiens H4 Activity 155.88 % 10.1073/pnas.0709695104
Homo sapiens H4 Activity 159.64 % 10.1073/pnas.0709695104
Homo sapiens H4 Activity 178.79 % 10.1073/pnas.0709695104
Homo sapiens H4 Activity 181.14 % 10.1073/pnas.0709695104
Homo sapiens HeLa TC50 8.3 uM 10.1128/aac.01324-07
Homo sapiens Hepatocyte T1/2 4.0 hr 10.1039/C1MD00227A
Homo sapiens HepG2 IC50 50000.0 nM 10.1073/pnas.1118370109
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 nan None None
Homo sapiens HERG Ki nan None None
Homo sapiens HFF IC50 10000.0 nM 10.1126/science.1087061
Homo sapiens Histamine H1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor IC50 nan None None
Homo sapiens Histamine H1 receptor Ki nan None None
Homo sapiens Histamine H2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor IC50 nan None None
Homo sapiens Histamine H2 receptor Ki nan None None
Homo sapiens Histamine H3 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HL-60 Activity nan None 10.1021/acsmedchemlett.7b00454
Homo sapiens HL-60 Inhibition nan % 10.1016/j.bmc.2012.08.062
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens Activity 0.15 ug ml-1 10.1128/aac.01096-07
Homo sapiens Homo sapiens Activity 3.98 ug ml-1 10.1128/aac.01096-07
Homo sapiens Homo sapiens Activity 4.26 ug ml-1 10.1128/aac.01096-07
Homo sapiens Homo sapiens Activity 64.0 ng/ml 10.1128/aac.01096-07
Homo sapiens Homo sapiens Activity nan None 10.1002/hep.27206
Homo sapiens Homo sapiens AUC 5856.81 ng.hr.mL-1 10.1093/toxsci/kft176
Homo sapiens Homo sapiens CL 7.4 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 7.5 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL 7.5 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 57.0 mL.min-1.kg-1 None
Homo sapiens Homo sapiens CL/F 31.2 L/hr 10.1124/dmd.111.043018
Homo sapiens Homo sapiens CL_renal 0.08 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL_renal 0.1 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens Cmax 770.0 nM 10.1002/hep.27206
Homo sapiens Homo sapiens Cmax 1108.4 nM None
Homo sapiens Homo sapiens Css 0.203 uM 10.1093/toxsci/kft176
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 7.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens Drugabsorption 40.3 mg/hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Homo sapiens Drugabsorption 142.1 mg/hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Homo sapiens EC50 23.0 nM 10.1021/jm00045a024
Homo sapiens Homo sapiens Excretion 1.0 % None
Homo sapiens Homo sapiens F 5.0 % 10.1021/jm400887j
Homo sapiens Homo sapiens F 20.0 % 10.1039/C5MD00575B
Homo sapiens Homo sapiens F 30.0 % 10.1039/C1MD00093D
Homo sapiens Homo sapiens F 30.8 % 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Homo sapiens F 33.0 % 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Homo sapiens F 35.0 % 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Homo sapiens F 44.0 % 10.1021/jm901846t
Homo sapiens Homo sapiens F 46.0 % 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Homo sapiens F 125.0 % None
Homo sapiens Homo sapiens Fa 0.86 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fabs 40.0 % 10.1124/dmd.110.034629
Homo sapiens Homo sapiens F_fraction 0.28 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fg 0.48 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fh 0.68 None 10.1021/jm901371v
Homo sapiens Homo sapiens IC50 60.0 nM 10.1016/s0960-894x(97)10205-0
Homo sapiens Homo sapiens T1/2 10.7 hr None
Homo sapiens Homo sapiens Tmax 1.5 hr None
Homo sapiens Homo sapiens Vd 4.5 L.kg-1 None
Homo sapiens Homo sapiens Vdss 3.3 L.kg-1 10.1021/jm901371v
Homo sapiens HUVEC Activity nan None 10.1021/acs.jnatprod.2c00153
Homo sapiens Ileal bile acid transporter Ki 24000.0 nM 10.1152/ajpgi.1998.274.1.g157
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens Jurkat Activity nan None 10.1016/j.bmc.2006.06.059
Homo sapiens Jurkat Activity nan None 10.1016/j.bmcl.2021.128235
Homo sapiens Jurkat Activity nan None 10.1128/aac.00660-09
Homo sapiens Jurkat EC50 5.0 nM 10.1128/aac.00660-09
Homo sapiens Jurkat EC50 6.7 nM 10.1016/j.bmcl.2010.09.036
Homo sapiens Jurkat IC50 7.0 nM 10.1021/jm010066k
Homo sapiens Jurkat IC50 8.0 nM 10.1016/S0960-894X(97)10005-1
Homo sapiens Jurkat IC50 8.0 nM 10.1021/jm010066k
Homo sapiens Jurkat IC50 11.0 nM 10.1016/j.bmc.2016.08.051
Homo sapiens Jurkat IC50 12.0 nM 10.1021/jm00021a005
Homo sapiens Jurkat IC50 1000.0 nM 10.1021/jm010066k
Homo sapiens Jurkat IC50 1900.0 nM 10.1016/j.bmc.2018.12.023
Homo sapiens Jurkat IC50 10000.0 nM 10.1021/jm010822m
Homo sapiens Jurkat IC50 10000.0 nM 10.1021/jm300630p
Homo sapiens Jurkat IC50 10000.0 nM 10.1021/jm981028c
Homo sapiens Jurkat Inhibition 50.0 % 10.1128/aac.01324-07
Homo sapiens Jurkat Inhibition 81.06 % 10.1016/j.bmcl.2011.08.020
Homo sapiens Jurkat Inhibition 91.0 % 10.1016/j.bmc.2016.08.051
Homo sapiens Jurkat Inhibition 99.0 % 10.1016/j.bmc.2016.08.051
Homo sapiens Jurkat Inhibition 100.0 % 10.1016/j.bmcl.2011.08.020
Homo sapiens K562 Rhodamine-123 accumulation 72.0 arbitrary units 10.1021/jm021099i
Homo sapiens K562 Rhodamine-123 accumulation 80.0 arbitrary units 10.1021/jm021099i
Homo sapiens K562 Rhodamine-123 accumulation 87.0 arbitrary units 10.1021/jm021099i
Homo sapiens K562 Rhodamine-123 accumulation 102.0 arbitrary units 10.1021/jm021099i
Homo sapiens K562 Survival 40.5 % 10.1021/jm501676v
Homo sapiens Kappa opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens KB Fold reversion 9.0 None 10.1021/jm960361i
Homo sapiens KB IC50 600.0 nM 10.1021/jm049949c
Homo sapiens KB Viability 82.0 % 10.1021/jm960361i
Homo sapiens KB 3-1 Amax 3.5 pmoles 10.1021/jm049949c
Homo sapiens KB 3-1 EC50 1200.0 nM 10.1021/jm049949c
Homo sapiens KB 3-1 IC50 1500.0 nM 10.1021/jm049949c
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens Liver microsome CLH 47.0 ug/min/mg 10.1021/acs.jmedchem.5b00128
Homo sapiens Liver microsome T1/2 0.4267 hr 10.1039/C1MD00227A
Homo sapiens Liver microsomes Activity nan None 10.1021/tx300075j
Homo sapiens Liver microsomes CL 29000.0 mL.min-1.g-1 10.1128/aac.00660-09
Homo sapiens Liver microsomes Stability nan % 10.1021/tx300075j
Homo sapiens Liver microsomes T1/2 0.4833 hr 10.1128/aac.00660-09
Homo sapiens LOX IMVI Activity nan None 10.1021/np010295+
Homo sapiens LXR-alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens LXR-beta AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens MCF7 Inhibition 19.3 % 10.1016/j.ejmech.2021.113336
Homo sapiens Melanocortin receptor 3 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens Monoamine oxidase A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Motilin receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens MT4 Activity nan None 10.1128/aac.01324-07
Homo sapiens MT4 CC50 5608.0 nM 10.1021/acs.jmedchem.8b00802
Homo sapiens Multidrug resistance associated protein Activity 26.3 % None
Homo sapiens Multidrug resistance-associated protein 1 Activity 37.0 % None
Homo sapiens Multidrug resistance-associated protein 1 Activity nan None None
Homo sapiens Multidrug resistance-associated protein 1 EC50 1700.0 nM 10.1021/acs.jmedchem.9b00963
Homo sapiens Multidrug resistance-associated protein 1 IC50 1412.0 nM 10.1021/acs.jmedchem.0c01826
Homo sapiens Multidrug resistance-associated protein 1 IC50 2700.0 nM 10.1016/j.bmc.2013.10.007
Homo sapiens Multidrug resistance-associated protein 1 IC50 2810.0 nM 10.1016/j.ejmech.2013.06.035
Homo sapiens Multidrug resistance-associated protein 1 IC50 2950.0 nM 10.1016/j.ejmech.2020.113045
Homo sapiens Multidrug resistance-associated protein 1 IC50 2970.0 nM 10.1021/acs.jmedchem.7b00441
Homo sapiens Multidrug resistance-associated protein 1 IC50 3530.0 nM 10.1016/j.ejmech.2017.08.020
Homo sapiens Multidrug resistance-associated protein 1 IC50 3530.0 nM 10.1016/j.ejmech.2018.10.026
Homo sapiens Multidrug resistance-associated protein 1 IC50 3770.0 nM 10.1021/acs.jmedchem.6b00330
Homo sapiens Multidrug resistance-associated protein 1 IC50 4780.0 nM 10.1016/j.bmcl.2008.07.127
Homo sapiens Multidrug resistance-associated protein 1 IC50 6630.0 nM 10.1021/acs.jmedchem.0c00961
Homo sapiens Multidrug resistance-associated protein 1 Inhibition 20.0 % 10.1016/j.ejmech.2020.113045
Homo sapiens Multidrug resistance-associated protein 1 Inhibition 100.0 % 10.1021/acs.jmedchem.5b00188
Homo sapiens Multidrug resistance-associated protein 1 Inhibition nan % 10.1016/j.bmcl.2012.08.024
Homo sapiens Multidrug resistance-associated protein 1 Inhibition nan % 10.1016/j.ejmech.2016.06.039
Homo sapiens Multidrug resistance-associated protein 1 Ki 5000.0 nM 10.1016/s0021-9258(18)46856-1
Homo sapiens Multidrug resistance-associated protein 4 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Multidrug resistance-associated protein 7 Activity 49.6 % 10.1124/mol.63.2.351
Homo sapiens Multidrug resistance protein 3 Activity nan None 10.1038/nrd3028
Homo sapiens Mu opioid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki nan None None
Homo sapiens NCI/ADR-RES Inhibition 22.7 % 10.1016/j.ejmech.2021.113336
Homo sapiens Neurokinin 1 receptor AC50 987.5 nM 10.1038/s41467-023-40064-9
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor AC50 11370.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neurokinin 2 receptor IC50 4139.0 nM None
Homo sapiens Neurokinin 2 receptor Ki 1380.0 nM None
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Neurotensin receptor 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Niemann-Pick C1 protein Potency 4466.8 nM None
Homo sapiens Norepinephrine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter IC50 nan None None
Homo sapiens Norepinephrine transporter Ki nan None None
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 6513.1 nM None
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 9688.5 nM None
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 16360.1 nM None
Homo sapiens Nuclear factor of activated T-cells cytoplasmic 1 Activity nan None 10.1016/j.bmcl.2021.128235
Homo sapiens Nuclear factor of activated T-cells cytoplasmic 1 Inhibition nan % 10.1016/j.bmcl.2021.128235
Homo sapiens Nuclear factor of activated T-cells cytoplasmic 1 Inhibition nan % 10.1016/j.ejmech.2022.114514
Homo sapiens Nuclear receptor subfamily 1 group I member 3 AC50 1200.0 nM 10.1038/s41467-023-40064-9
Homo sapiens PBMC Activity 26.0 % 10.1016/j.bmcl.2011.10.081
Homo sapiens PBMC Activity nan None 10.1021/np010414l
Homo sapiens PBMC Activity nan None 10.1128/aac.01324-07
Homo sapiens PBMC EC50 3.1 nM 10.1128/aac.00660-09
Homo sapiens PBMC FC 10.0 None 10.1128/aac.01324-07
Homo sapiens PBMC IC50 3.0 nM 10.1039/C1MD00227A
Homo sapiens PBMC IC50 12.0 nM 10.1021/np0401056
Homo sapiens PBMC Inhibition 3.7 % 10.1016/j.bmcl.2011.10.081
Homo sapiens PBMC Inhibition 25.5 % 10.1021/np9003678
Homo sapiens PBMC Inhibition 32.0 % 10.1021/jm8000746
Homo sapiens PBMC Inhibition 50.0 % 10.1128/aac.00660-09
Homo sapiens PBMC Inhibition 65.7 % 10.1021/jm8000746
Homo sapiens PBMC Inhibition 68.0 % 10.1021/np9003678
Homo sapiens PBMC Inhibition 75.2 % 10.1021/jm8000746
Homo sapiens PBMC Inhibition 89.9 % 10.1021/np9003678
Homo sapiens PBMC Inhibition nan % 10.1016/j.bmcl.2011.10.081
Homo sapiens Peptidyl-prolyl cis-trans isomerase D IC50 3.6 nM 10.1021/acsmedchemlett.5b00451
Homo sapiens Peptidyl-prolyl cis-trans isomerase D Kd 13.0 nM 10.1021/acs.jmedchem.5b01801
Homo sapiens Peptidyl-prolyl cis-trans isomerase D Kd 30.0 nM 10.1016/j.bmcl.2019.126717
Homo sapiens Peptidyl-prolyl cis-trans isomerase D Ki 2.58 nM 10.1021/acsmedchemlett.5b00451
Homo sapiens Peptidyl-prolyl cis-trans isomerase D Ki 7.0 nM 10.1021/ml1001272
Homo sapiens Peptidyl-prolyl cis-trans isomerase D Ki 8.2 nM 10.1021/acs.jmedchem.5b01801
Homo sapiens Peptidyl-prolyl cis-trans isomerase D Ki 34.0 nM 10.1021/ml1001272
Homo sapiens Peroxisome proliferator-activated receptor alpha AC50 10999.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Peroxisome proliferator-activated receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Peroxisome proliferator-activated receptor delta Potency 28183.8 nM None
Homo sapiens Peroxisome proliferator-activated receptor gamma Potency 6309.6 nM None
Homo sapiens Peroxisome proliferator-activated receptor gamma Potency 10000.0 nM None
Homo sapiens P-glycoprotein 1 Activity 0.0 % 10.1016/s0006-2952(96)00656-9
Homo sapiens P-glycoprotein 1 Activity 1.1 uM 10.1074/jbc.m706175200
Homo sapiens P-glycoprotein 1 Activity 1.58 % None
Homo sapiens P-glycoprotein 1 Activity 2.19 % None
Homo sapiens P-glycoprotein 1 Activity 5.0 % 10.1016/s0006-2952(96)00656-9
Homo sapiens P-glycoprotein 1 Activity 5.0 None 10.1016/j.bmc.2007.09.039
Homo sapiens P-glycoprotein 1 Activity 9.8 nM/mg*min 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 Activity 11.0 uM 10.1074/jbc.m706175200
Homo sapiens P-glycoprotein 1 Activity 15.0 uM 10.1074/jbc.m706175200
Homo sapiens P-glycoprotein 1 Activity 30.0 % 10.1124/jpet.102.045096
Homo sapiens P-glycoprotein 1 Activity 40.0 % 10.1124/jpet.103.055574
Homo sapiens P-glycoprotein 1 Activity 43.0 % 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 Activity 50.0 % 10.1124/jpet.102.045096
Homo sapiens P-glycoprotein 1 Activity 437.0 % 10.1016/j.bmc.2007.10.006
Homo sapiens P-glycoprotein 1 Activity nan None 10.1006/taap.2002.9461
Homo sapiens P-glycoprotein 1 Activity nan None 10.1007/s004240050829
Homo sapiens P-glycoprotein 1 Activity nan None 10.1016/j.bbrc.2004.01.156
Homo sapiens P-glycoprotein 1 Activity nan None 10.1016/j.bmc.2003.08.013
Homo sapiens P-glycoprotein 1 Activity nan None 10.1016/j.bmc.2007.10.006
Homo sapiens P-glycoprotein 1 Activity nan None 10.1016/j.bmc.2008.01.055
Homo sapiens P-glycoprotein 1 Activity nan None 10.1016/j.ejphar.2003.11.035
Homo sapiens P-glycoprotein 1 Activity nan None 10.1016/j.jconrel.2003.12.006
Homo sapiens P-glycoprotein 1 Activity nan None 10.1016/j.neuropharm.2006.07.038
Homo sapiens P-glycoprotein 1 Activity nan None 10.1016/s0009-9236(97)90027-8
Homo sapiens P-glycoprotein 1 Activity nan None 10.1021/jm701267q
Homo sapiens P-glycoprotein 1 Activity nan None 10.1021/np010295+
Homo sapiens P-glycoprotein 1 Activity nan None 10.1023/a:1011076217118
Homo sapiens P-glycoprotein 1 Activity nan None 10.1023/a:1011902625609
Homo sapiens P-glycoprotein 1 Activity nan None 10.1023/a:1013358126640
Homo sapiens P-glycoprotein 1 Activity nan None 10.1023/a:1024422625596
Homo sapiens P-glycoprotein 1 Activity nan None 10.1023/a:1025001131513
Homo sapiens P-glycoprotein 1 Activity nan None 10.1038/nrd3028
Homo sapiens P-glycoprotein 1 Activity nan None 10.1038/sj.bjp.0706008
Homo sapiens P-glycoprotein 1 Activity nan None 10.1038/sj.leu.2400698
Homo sapiens P-glycoprotein 1 Activity nan None 10.1128/aac.00671-07
Homo sapiens P-glycoprotein 1 Activity nan None 10.1152/ajpcell.00418.2002
Homo sapiens P-glycoprotein 1 Activity nan None None
Homo sapiens P-glycoprotein 1 Alpha max 0.92 None 10.1021/jm101421d
Homo sapiens P-glycoprotein 1 EC50 32.0 nM 10.1021/acs.jmedchem.5b00085
Homo sapiens P-glycoprotein 1 EC50 32.0 nM 10.1021/acs.jmedchem.9b00963
Homo sapiens P-glycoprotein 1 EC50 32.0 nM 10.1021/jm400930e
Homo sapiens P-glycoprotein 1 EC50 43.0 nM 10.1021/acs.jmedchem.5b00085
Homo sapiens P-glycoprotein 1 EC50 600.0 nM 10.1021/jm010126m
Homo sapiens P-glycoprotein 1 EC50 45500.0 nM 10.1016/j.bmcl.2008.05.055
Homo sapiens P-glycoprotein 1 EC50 80000.0 nM 10.1016/j.bmc.2007.09.039
Homo sapiens P-glycoprotein 1 EC50 80000.0 nM 10.1021/jm701267q
Homo sapiens P-glycoprotein 1 EC50 nan None 10.1021/acs.jmedchem.5b00085
Homo sapiens P-glycoprotein 1 FC 1.2 None 10.1021/jm300378k
Homo sapiens P-glycoprotein 1 FC 5.0 None 10.1016/j.ejmech.2015.02.056
Homo sapiens P-glycoprotein 1 FC 91.6 None 10.1021/jm100035c
Homo sapiens P-glycoprotein 1 Hill coefficient 3.63 None 10.1016/j.bmc.2007.07.024
Homo sapiens P-glycoprotein 1 IC50 102.33 nM 10.1021/jm201705f
Homo sapiens P-glycoprotein 1 IC50 141.3 nM 10.1021/acs.jmedchem.0c01826
Homo sapiens P-glycoprotein 1 IC50 436.52 nM 10.1016/j.bmc.2007.11.057
Homo sapiens P-glycoprotein 1 IC50 440.0 nM 10.1016/j.bmc.2007.11.057
Homo sapiens P-glycoprotein 1 IC50 500.0 nM 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 IC50 650.0 nM 10.1021/jm101421d
Homo sapiens P-glycoprotein 1 IC50 670.0 nM 10.1021/ml100118k
Homo sapiens P-glycoprotein 1 IC50 676.0 nM 10.1021/acs.jmedchem.8b01821
Homo sapiens P-glycoprotein 1 IC50 729.0 nM 10.1039/C1MD00227A
Homo sapiens P-glycoprotein 1 IC50 800.0 nM 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 IC50 919.0 nM 10.1021/acs.jmedchem.5b00188
Homo sapiens P-glycoprotein 1 IC50 920.0 nM 10.1016/j.bmc.2013.10.007
Homo sapiens P-glycoprotein 1 IC50 990.0 nM 10.1016/j.ejmech.2013.06.035
Homo sapiens P-glycoprotein 1 IC50 1090.0 nM 10.1021/acs.jmedchem.6b00035
Homo sapiens P-glycoprotein 1 IC50 1170.0 nM 10.1016/j.ejmech.2018.10.026
Homo sapiens P-glycoprotein 1 IC50 1200.0 nM 10.1016/j.ejmech.2020.113045
Homo sapiens P-glycoprotein 1 IC50 1200.0 nM 10.1021/acs.jmedchem.0c00961
Homo sapiens P-glycoprotein 1 IC50 1210.0 nM 10.1016/j.ejmech.2016.09.010
Homo sapiens P-glycoprotein 1 IC50 1210.0 nM 10.1016/j.ejmech.2017.08.020
Homo sapiens P-glycoprotein 1 IC50 1210.0 nM 10.1021/acs.jmedchem.6b00330
Homo sapiens P-glycoprotein 1 IC50 1210.0 nM 10.1021/acs.jmedchem.7b00441
Homo sapiens P-glycoprotein 1 IC50 1300.0 nM None
Homo sapiens P-glycoprotein 1 IC50 1400.0 nM 10.1006/bbrc.2001.6000
Homo sapiens P-glycoprotein 1 IC50 1400.0 nM 10.1016/j.bmc.2009.01.072
Homo sapiens P-glycoprotein 1 IC50 1410.0 nM 10.1016/j.ejmech.2016.03.067
Homo sapiens P-glycoprotein 1 IC50 1412.54 nM 10.1016/j.bmc.2007.07.024
Homo sapiens P-glycoprotein 1 IC50 1412.54 nM 10.1016/j.bmc.2007.11.057
Homo sapiens P-glycoprotein 1 IC50 1412.54 nM 10.1016/j.bmc.2008.07.034
Homo sapiens P-glycoprotein 1 IC50 1700.0 nM 10.1006/bbrc.2001.6000
Homo sapiens P-glycoprotein 1 IC50 1800.0 nM 10.1006/bbrc.2001.6000
Homo sapiens P-glycoprotein 1 IC50 2100.0 nM 10.1006/bbrc.2001.6000
Homo sapiens P-glycoprotein 1 IC50 2400.0 nM 10.1006/bbrc.2001.6000
Homo sapiens P-glycoprotein 1 IC50 3400.0 nM 10.1021/jm0109863
Homo sapiens P-glycoprotein 1 IC50 3410.0 nM 10.1021/jm990955w
Homo sapiens P-glycoprotein 1 IC50 3660.0 nM 10.1111/j.1349-7006.1998.tb00518.x
Homo sapiens P-glycoprotein 1 IC50 4300.0 nM 10.1006/bbrc.2001.6000
Homo sapiens P-glycoprotein 1 IC50 4920.0 nM 10.1016/j.bmcl.2008.07.127
Homo sapiens P-glycoprotein 1 IC50 9340.0 nM 10.1128/aac.00671-07
Homo sapiens P-glycoprotein 1 IC50 59100.0 nM 10.1016/j.ejmech.2021.113336
Homo sapiens P-glycoprotein 1 Inhibition 20.0 % 10.1016/j.ejmech.2020.113045
Homo sapiens P-glycoprotein 1 Inhibition 43.0 % 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 Inhibition 92.0 % 10.1021/ml200293c
Homo sapiens P-glycoprotein 1 Inhibition 100.0 % 10.1016/j.bmcl.2013.11.068
Homo sapiens P-glycoprotein 1 Inhibition 100.0 % 10.1021/acs.jmedchem.5b00188
Homo sapiens P-glycoprotein 1 Inhibition nan % 10.1016/j.bmcl.2012.08.024
Homo sapiens P-glycoprotein 1 Inhibition nan % 10.1016/j.ejmech.2016.06.039
Homo sapiens P-glycoprotein 1 Inhibition nan % 10.1021/acsmedchemlett.8b00324
Homo sapiens P-glycoprotein 1 Inhibition nan % 10.1021/jm5005623
Homo sapiens P-glycoprotein 1 Inhibition nan % 10.1021/np100429s
Homo sapiens P-glycoprotein 1 Inhibition nan % 10.1021/np400950h
Homo sapiens P-glycoprotein 1 Ki 20.0 nM None
Homo sapiens P-glycoprotein 1 Ki 350.0 nM 10.1023/a:1022359300826
Homo sapiens P-glycoprotein 1 Ki 1300.0 nM 10.1124/mol.61.5.964
Homo sapiens P-glycoprotein 1 Ki 1800.0 nM 10.1006/bbrc.1999.0475
Homo sapiens P-glycoprotein 1 Ki 2180.0 nM 10.1023/a:1016140429238
Homo sapiens P-glycoprotein 1 Ki 4660.0 nM 10.1124/mol.61.5.964
Homo sapiens P-glycoprotein 1 Km 170.0 nM 10.1023/a:1013358126640
Homo sapiens P-glycoprotein 1 Km 3800.0 nM 10.1111/j.1476-5381.1996.tb15612.x
Homo sapiens P-glycoprotein 1 Km 8400.0 nM 10.1016/s0021-9258(18)53221-x
Homo sapiens P-glycoprotein 1 % maximum response 98.7 % None
Homo sapiens P-glycoprotein 1 Papp 1.6 nm/s 10.1128/aac.00660-09
Homo sapiens P-glycoprotein 1 Papp 5.7 nm/s 10.1128/aac.00660-09
Homo sapiens P-glycoprotein 1 Papp 9.3 nm/s 10.1128/aac.00660-09
Homo sapiens P-glycoprotein 1 Papp 15.9 nm/s None
Homo sapiens P-glycoprotein 1 Papp 153.0 nm/s None
Homo sapiens P-glycoprotein 1 Papp 446.0 nm/s 10.1128/aac.00660-09
Homo sapiens P-glycoprotein 1 Ratio 1.0 None 10.1021/jm401966m
Homo sapiens P-glycoprotein 1 Ratio 1.01 None 10.1021/acsmedchemlett.8b00324
Homo sapiens P-glycoprotein 1 Ratio 1.15 None 10.1021/acsmedchemlett.8b00324
Homo sapiens P-glycoprotein 1 Ratio 1.16 None 10.1021/acsmedchemlett.8b00324
Homo sapiens P-glycoprotein 1 Ratio 1.2 None 10.1021/jm401966m
Homo sapiens P-glycoprotein 1 Ratio 1.25 None 10.1021/acsmedchemlett.8b00324
Homo sapiens P-glycoprotein 1 Ratio 1.3 None 10.1021/acsmedchemlett.8b00324
Homo sapiens P-glycoprotein 1 Ratio 1.4 None 10.1021/acsmedchemlett.8b00324
Homo sapiens P-glycoprotein 1 Ratio 1.43 None 10.1021/acsmedchemlett.8b00324
Homo sapiens P-glycoprotein 1 Ratio 1.44 None 10.1021/acsmedchemlett.8b00324
Homo sapiens P-glycoprotein 1 Ratio 1.46 None 10.1021/acsmedchemlett.8b00324
Homo sapiens P-glycoprotein 1 Ratio 1.47 None 10.1021/acsmedchemlett.8b00324
Homo sapiens P-glycoprotein 1 Ratio 1.6 None 10.1128/aac.00660-09
Homo sapiens P-glycoprotein 1 Ratio 5.2 None 10.1021/jm401966m
Homo sapiens P-glycoprotein 1 Ratio 20.8 None 10.1021/jm401966m
Homo sapiens P-glycoprotein 1 Ratio 279.0 None 10.1128/aac.00660-09
Homo sapiens P-glycoprotein 1 Ratio_ATPase activity 0.85 None None
Homo sapiens P-glycoprotein 1 Ratio_Papp 9.61 None None
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Plasma AUC 3689.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma AUC 4471.0 ng.hr.mL-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma AUC 4471.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma AUC 5971.0 ng.hr.mL-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma AUC 6637.0 ng.hr.mL-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma AUC 8799.0 ng.hr.mL-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma AUC 11556.0 ng.hr.mL-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma CL 6.5 mL.min-1.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma CL 7.5 mL.min-1.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma CL 7.667 mL.min-1.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma CL 7.833 mL.min-1.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma CL 7.85 mL.min-1.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma CL 8.333 mL.min-1.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma CL 11.62 mL.min-1.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma CL 11.67 mL.min-1.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma Cmax 303.5 nM 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Cmax 610.33 nM 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma Cmax 618.64 nM 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Cmax 681.84 nM 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma Cmax 1047.7 nM 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Cmax 1712.91 nM 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma F 21.0 % 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma F 21.0 % 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma F 24.0 % 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma F 79.0 % 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma fCmax 0.054 uM 10.1124/dmd.111.040758
Homo sapiens Plasma MAT 3.22 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma MAT 3.56 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma MAT 5.54 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma MRT 2.53 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma MRT 2.71 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma MRT 3.67 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma PPB 99.0 % 10.1039/C1MD00227A
Homo sapiens Plasma Ratio 1.09 None 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Ratio 1.45 None 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Ratio 1.58 None 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Ratio 4.29 None 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma T1/2 0.41 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma T1/2 0.48 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma T1/2 0.5 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma T1/2 4.1 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma T1/2 4.91 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma T1/2 5.6 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Tmax 1.8 hr 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Tmax 3.3 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma Tmax 5.1 hr 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma Vd 0.609 L.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Vd 0.806 L.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Vdss 1.19 L.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Vdss 1.2 L.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Plasma Vdss 1.85 L.kg-1 10.1002/j.1552-4604.1990.tb01868.x
Homo sapiens Plasma Vdss 2.38 L.kg-1 10.1002/j.1552-4604.1994.tb03967.x
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Rap guanine nucleotide exchange factor 3 Potency 2511.9 nM None
Homo sapiens RD CC50 10000.0 nM 10.1016/j.bmcl.2015.11.002
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens Retinoic acid receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Retinoic acid receptor beta AC50 6000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Retinoic acid receptor beta AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Retinoic acid receptor gamma AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Retinoid X receptor alpha Potency 15848.9 nM None
Homo sapiens SAOS-2 Activity nan None 10.1021/np400950h
Homo sapiens Serine/threonine-protein kinase mTOR Inhibition 10.0 % 10.1016/j.bmcl.2017.04.034
Homo sapiens Serine/threonine-protein kinase mTOR Inhibition nan % 10.1016/j.bmcl.2017.04.034
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Activity nan None 10.1016/j.bmcl.2021.128235
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 183.0 nM 10.1021/jm025595i
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Inhibition nan % 10.1016/j.bmcl.2016.10.050
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Kd 4.0 nM 10.1016/0960-894X(95)00404-H
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 8600.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki nan None None
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki nan None None
Homo sapiens Serotonin 7 (5-HT7) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter IC50 nan None None
Homo sapiens Serotonin transporter Ki nan None None
Homo sapiens SH-SY5Y Activity 57.4 % 10.1016/j.ejmech.2021.113168
Homo sapiens SH-SY5Y Activity 74.5 % 10.1016/j.ejmech.2021.113168
Homo sapiens SH-SY5Y Activity 82.0 % 10.1016/j.ejmech.2021.113168
Homo sapiens SH-SY5Y Activity 83.5 % 10.1016/j.ejmech.2021.113168
Homo sapiens SH-SY5Y Activity 86.4 % 10.1016/j.ejmech.2021.113168
Homo sapiens SH-SY5Y Activity 89.1 % 10.1016/j.ejmech.2021.113168
Homo sapiens SH-SY5Y Activity 99.32 % 10.1016/j.ejmech.2021.113168
Homo sapiens SH-SY5Y Activity 103.6 % 10.1016/j.ejmech.2021.113168
Homo sapiens SH-SY5Y Activity 120.7 % 10.1016/j.ejmech.2021.113168
Homo sapiens SH-SY5Y Activity nan None 10.1016/j.ejmech.2021.113168
Homo sapiens SH-SY5Y Inhibition nan % 10.1016/j.ejmech.2021.113168
Homo sapiens Sigma opioid receptor IC50 nan None None
Homo sapiens Sigma opioid receptor Ki nan None None
Homo sapiens SK-HEP1 Activity 80.0 % 10.1016/j.ejmech.2011.02.023
Homo sapiens Skin Activity nan None 10.1128/aac.00492-07
Homo sapiens Solute carrier family 22 member 1 Inhibition 3.5 % 10.1021/jm8003152
Homo sapiens Solute carrier organic anion transporter family member 1B1 Activity 6.1 % 10.1211/0022357021440
Homo sapiens Solute carrier organic anion transporter family member 1B1 Activity nan None 10.1038/nrd3028
Homo sapiens Solute carrier organic anion transporter family member 1B1 Activity nan None 10.1124/jpet.102.043026
Homo sapiens Solute carrier organic anion transporter family member 1B1 IC50 700.0 nM 10.1124/dmd.111.042382
Homo sapiens Solute carrier organic anion transporter family member 1B1 IC50 750.0 nM 10.1021/acs.jmedchem.0c01484
Homo sapiens Solute carrier organic anion transporter family member 1B1 IC50 1200.0 nM 10.1124/dmd.111.042382
Homo sapiens Solute carrier organic anion transporter family member 1B1 IC50 1400.0 nM 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition 4.605 % 10.1124/mol.112.084152
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition 96.8 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 1B1 Ki 200.0 nM 10.1007/s00210-003-0814-4
Homo sapiens Solute carrier organic anion transporter family member 1B1 Ki 200.0 nM 10.1124/dmd.111.042382
Homo sapiens Solute carrier organic anion transporter family member 1B1 Ki 238.0 nM 10.1124/jpet.102.041921
Homo sapiens Solute carrier organic anion transporter family member 1B1 Ki 1300.0 nM 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 1B3 Activity nan None 10.1038/nrd3028
Homo sapiens Solute carrier organic anion transporter family member 1B3 IC50 1300.0 nM 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition 4.221 % 10.1124/mol.112.084152
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition 103.7 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 1B3 Ki 1200.0 nM 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 2B1 Activity nan None 10.1038/nrd3028
Homo sapiens Solute carrier organic anion transporter family member 2B1 IC50 37000.0 nM 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 2B1 Inhibition 14.0 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 2B1 Ki 36000.0 nM 10.1021/jm300212s
Homo sapiens Thromboxane A2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Type-1 angiotensin II receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine-protein kinase FYN IC50 nan None None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase JAK1 Inhibition nan % 10.1016/j.bmcl.2011.10.081
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 2909.3 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 5173.5 nM None
Homo sapiens Ubiquitin carboxyl-terminal hydrolase 1 Potency 354813.4 nM None
Homo sapiens UDP-glucuronosyltransferase 2B7 Km 202000.0 nM 10.1016/j.pharmthera.2004.10.013
Homo sapiens UDP-glucuronosyltransferase 2B7 Vmax 99.0 pmol/min/mg protein 10.1016/j.pharmthera.2004.10.013
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vitamin D receptor Potency 17782.8 nM None
Human alphaherpesvirus 1 Human alphaherpesvirus 1 IC50 8300.0 nM 10.1128/aac.01324-07
Human alphaherpesvirus 2 Human alphaherpesvirus 2 IC50 8300.0 nM 10.1128/aac.01324-07
Human alphaherpesvirus 3 Human alphaherpesvirus 3 IC50 3300.0 nM 10.1128/aac.01324-07
Human betaherpesvirus 5 Human betaherpesvirus 5 IC50 18300.0 nM 10.1128/aac.01324-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity 96.0 % 10.1021/jm050716a
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 450.0 nM 10.1016/j.bmcl.2013.05.101
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 450.0 nM 10.1128/aac.01324-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 540.0 nM 10.1128/aac.01324-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 830.0 nM 10.1128/aac.01324-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition 100.0 % 10.1016/j.ejmech.2011.02.023
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 455.0 nM 10.1016/j.bmcl.2003.09.042
Human papillomavirus type 16 Human papillomavirus type 16 IC50 400.0 nM 10.1128/aac.01324-07
Human papillomavirus type 16 Human papillomavirus type 16 TC50 0.3 uM 10.1128/aac.01324-07
Human respirovirus 3 Human respirovirus 3 IC50 nan None 10.1128/aac.01324-07
Influenza A virus Influenza A virus IC50 14800.0 nM 10.1128/aac.01324-07
Influenza A virus Nonstructural protein 1 Potency 4466.8 nM None
Influenza B virus Influenza B virus IC50 14800.0 nM 10.1128/aac.01324-07
Kluyveromyces marxianus Kluyveromyces marxianus Activity nan None 10.1128/aac.01096-07
Kluyveromyces marxianus Kluyveromyces marxianus IZ 15.5 mm 10.1128/aac.01096-07
Kluyveromyces marxianus Kluyveromyces marxianus IZ 20.5 mm 10.1128/aac.01096-07
Kluyveromyces marxianus Kluyveromyces marxianus IZ 23.3 mm 10.1128/aac.01096-07
Macaca fascicularis Cynomolgus monkey MST 39.0 day 10.1126/science.1087061
Mus musculus B-cell line IC50 740.0 nM 10.1021/acs.jnatprod.2c00204
Mus musculus B-cell line IC50 nan None 10.1021/acs.jnatprod.9b01167
Mus musculus Bile salt export pump Activity 19.6 % 10.1053/jhep.2001.24171
Mus musculus Bile salt export pump Activity nan None None
Mus musculus C2C12 Activity nan None 10.1038/nchembio.301
Mus musculus C2C12 Inhibition nan % 10.1038/nchembio.301
Mus musculus EMT6 IC50 440.0 nM 10.1016/s0960-894x(99)00030-x
Mus musculus HT-22 Activity 90.0 % 10.1016/j.ejmech.2014.07.027
Mus musculus HT-22 Activity 90.0 % 10.1016/j.ejmech.2017.09.033
Mus musculus HT-22 Activity 90.0 % 10.1016/j.ejmech.2017.09.043
Mus musculus HT-22 Activity 90.0 % 10.1016/j.ejmech.2017.12.045
Mus musculus HT-22 Activity 90.0 % 10.1016/j.ejmech.2018.07.068
Mus musculus HT-22 Activity nan None 10.1016/j.ejmech.2017.12.045
Mus musculus Interleukin-2 Activity nan None 10.1016/0960-894X(95)00281-W
Mus musculus Interleukin-2 IC50 5.0 nM 10.1021/jm00017a020
Mus musculus L929 IC50 29900.0 nM 10.1016/j.ejmech.2021.113795
Mus musculus L929 IC50 30000.0 nM 10.1021/acs.jmedchem.5b00085
Mus musculus L929 IC50 33900.0 nM 10.1021/jm201121b
Mus musculus L929 IC50 33900.0 nM 10.1021/jm400930e
Mus musculus Liver T1/2 0.5617 hr 10.1039/C1MD00227A
Mus musculus Monoamine oxidase A Activity nan None 10.1021/jm800656v
Mus musculus Monoamine oxidase B Activity nan None 10.1021/jm800656v
Mus musculus Mus musculus Activity 2.0 % 10.1073/pnas.0702955104
Mus musculus Mus musculus Activity 5.0 None 10.1016/j.ejmech.2008.01.035
Mus musculus Mus musculus Activity 6.1 None 10.1016/j.ejmech.2008.01.035
Mus musculus Mus musculus Activity 47.3 % 10.1016/j.bmc.2019.02.054
Mus musculus Mus musculus Activity 73.0 % 10.1021/acs.jmedchem.1c01403
Mus musculus Mus musculus Activity 82.0 % 10.1016/j.ejmech.2016.11.017
Mus musculus Mus musculus Activity 953.0 None 10.1016/j.ejmech.2008.01.035
Mus musculus Mus musculus Activity 1617.0 None 10.1016/j.ejmech.2008.01.035
Mus musculus Mus musculus Activity nan None 10.1016/j.ejmech.2021.113791
Mus musculus Mus musculus Activity nan None 10.1021/acs.jmedchem.0c00272
Mus musculus Mus musculus Activity nan None 10.1021/acs.jmedchem.5b01064
Mus musculus Mus musculus Activity nan None 10.1021/ml2000998
Mus musculus Mus musculus Activity nan None 10.1021/ml4004809
Mus musculus Mus musculus Activity_index 11.6 None 10.1016/j.bmc.2019.02.054
Mus musculus Mus musculus Activity_index 41.8 None 10.1016/j.bmc.2019.02.054
Mus musculus Mus musculus Body weight 19.0 g 10.1016/S0960-894X(97)10072-5
Mus musculus Mus musculus CC50 1290.0 nM 10.1021/jm048979c
Mus musculus Mus musculus EC50 17.8 nM 10.1021/jm00045a024
Mus musculus Mus musculus ED50 10.0 mg.kg-1 10.1021/jm7010996
Mus musculus Mus musculus ED50 45.0 mg.kg-1 10.1016/s0960-894x(99)00220-6
Mus musculus Mus musculus graft survival 1.0 day 10.1016/S0960-894X(97)10072-5
Mus musculus Mus musculus IC50 0.004 ug.mL-1 10.1016/s0960-894x(99)00220-6
Mus musculus Mus musculus IC50 0.008 ug.mL-1 10.1021/jm00011a004
Mus musculus Mus musculus IC50 0.02 ug.mL-1 10.1021/jm00011a004
Mus musculus Mus musculus IC50 0.0518 ug.mL-1 10.1016/S0960-894X(97)10072-5
Mus musculus Mus musculus IC50 0.0518 ug.mL-1 10.1021/jm960023h
Mus musculus Mus musculus IC50 2.5 nM 10.1016/s0960-894x(99)00621-6
Mus musculus Mus musculus IC50 6.0 nM 10.1021/jm010822m
Mus musculus Mus musculus IC50 6.0 nM 10.1021/jm981028c
Mus musculus Mus musculus IC50 7.5 nM 10.1016/s0960-894x(99)00621-6
Mus musculus Mus musculus IC50 10.0 nM 10.1021/jm960391l
Mus musculus Mus musculus IC50 14.0 nM 10.1016/0960-894X(95)00126-E
Mus musculus Mus musculus IC50 20.0 nM 10.1021/jm00017a020
Mus musculus Mus musculus IC50 20.0 nM 10.1021/jm00048a002
Mus musculus Mus musculus IC50 40.0 nM 10.1021/jm00021a005
Mus musculus Mus musculus IC50 73.0 nM 10.1021/jm981079+
Mus musculus Mus musculus IC50 242.0 nM 10.1021/jm981079+
Mus musculus Mus musculus IC50 100000.0 nM 10.1021/jm981028c
Mus musculus Mus musculus Inhibition 48.0 % 10.1021/jm970039n
Mus musculus Mus musculus Inhibition 55.1 % 10.1021/jm5013006
Mus musculus Mus musculus Inhibition 82.0 % 10.1016/j.bmcl.2010.04.112
Mus musculus Mus musculus Inhibition 83.0 % 10.1021/jm970039n
Mus musculus Mus musculus Inhibition nan % 10.1021/acs.jmedchem.8b00521
Mus musculus Mus musculus Mean graft survival 9.8 day 10.1016/S0960-894X(97)10072-5
Mus musculus Mus musculus Paw weight 163.0 mg 10.1021/jm00170a003
Mus musculus Mus musculus Ratio 1.0 None 10.1016/S0960-894X(01)80716-2
Mus musculus Mus musculus Relative IC50 1.0 None 10.1016/S0960-894X(01)80127-X
Mus musculus Mus musculus Selectivity index 7.0 None 10.1021/jm048979c
Mus musculus Mus musculus Selectivity index 963.0 None 10.1021/jm048979c
Mus musculus Mus musculus Stimulation index 0.18 None 10.1016/s0960-894x(98)00022-5
Mus musculus Mus musculus Survival 11.8 day 10.1016/j.bmcl.2009.05.054
Mus musculus Mus musculus Survival 30.0 day 10.1021/jm101254z
Mus musculus Mus musculus Weight change 2.7 % 10.1016/S0960-894X(97)10072-5
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Mus musculus P388 Fold reversion 260.0 None 10.1021/jm960361i
Mus musculus P388 Viability 65.0 % 10.1021/jm960361i
Mus musculus Peptidyl-prolyl cis-trans isomerase F, mitochondrial Activity 46.0 % 10.1016/j.ejmech.2016.12.057
Mus musculus Peptidyl-prolyl cis-trans isomerase F, mitochondrial Inhibition nan % 10.1021/acsmedchemlett.5b00451
Mus musculus Peptidyl-prolyl cis-trans isomerase F, mitochondrial Ratio 46.0 % 10.1016/j.ejmech.2018.07.068
Mus musculus Peripheral-type benzodiazepine receptor Activity -46.0 % 10.1016/j.ejmech.2016.11.017
Mus musculus Peripheral-type benzodiazepine receptor Activity -46.0 % 10.1016/j.ejmech.2017.09.033
Mus musculus Peripheral-type benzodiazepine receptor Activity 55.0 % 10.1016/j.ejmech.2016.11.017
Mus musculus Peripheral-type benzodiazepine receptor Activity 55.0 % 10.1016/j.ejmech.2017.09.033
Mus musculus P-glycoprotein 1 Activity nan None 10.1016/j.neuropharm.2006.07.038
Mus musculus P-glycoprotein 1 IC50 700.0 nM 10.1021/jm021012t
Mus musculus P-glycoprotein 1 Ki 3500.0 nM 10.1124/jpet.102.037549
Mus musculus P-glycoprotein 3 Activity nan None 10.1016/j.neuropharm.2006.07.038
Mus musculus P-glycoprotein 3 Activity nan None 10.1023/a:1023847521767
Mus musculus P-glycoprotein 3 Activity nan None 10.1046/j.1440-1681.2000.03308.x
Mus musculus P-glycoprotein 3 Activity nan None 10.1172/jci118214
Mus musculus P-glycoprotein 3 Activity nan None None
Mus musculus P-glycoprotein 3 IC50 4800.0 nM 10.1021/jm021012t
Mus musculus P-glycoprotein 3 Ki 3650.0 nM 10.1124/jpet.102.037549
Mus musculus P-glycoprotein 3 Ratio 1.3 None 10.1021/jm021012t
Mus musculus P-glycoprotein 3 Ratio 8.5 None 10.1021/jm021012t
Mus musculus P-glycoprotein 3 Ratio 10.2 None 10.1021/jm021012t
Mus musculus Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform IC50 570.0 nM 10.1016/j.ejmech.2015.12.020
Mus musculus Plasma Ratio AUC 0.6 None 10.1124/dmd.110.034629
Mus musculus Scavenger receptor class B member 1 AbsAC40_uM 35.0 uM None
Mus musculus Splenocyte Activity 96.8 % 10.1021/ml2000998
Mus musculus Splenocyte Activity 97.1 % 10.1021/ml2000998
Mus musculus Splenocyte CC50 1200.0 nM 10.1016/j.bmc.2019.06.030
Mus musculus Splenocyte CC50 1200.0 nM 10.1021/acs.jmedchem.8b01430
Mus musculus Splenocyte CC50 2500.0 nM 10.1021/acs.jnatprod.1c01085
Mus musculus Splenocyte CC50 7330.0 nM 10.1021/acs.jnatprod.2c00204
Mus musculus Splenocyte CC50 nan None 10.1021/acs.jnatprod.2c00766
Mus musculus Splenocyte EC50 30.0 nM 10.1021/acs.jnatprod.2c00766
Mus musculus Splenocyte IC50 10.0 nM 10.1016/j.bmcl.2009.05.043
Mus musculus Splenocyte IC50 10.0 nM 10.1016/j.bmcl.2009.05.054
Mus musculus Splenocyte IC50 17.0 nM 10.1021/jm901108b
Mus musculus Splenocyte IC50 30.0 nM 10.1016/j.bmcl.2012.08.068
Mus musculus Splenocyte IC50 30.0 nM 10.1021/acs.jnatprod.1c01085
Mus musculus Splenocyte IC50 40.0 nM 10.1016/j.bmc.2019.06.030
Mus musculus Splenocyte IC50 40.0 nM 10.1021/acs.jmedchem.8b01430
Mus musculus Splenocyte IC50 70.0 nM 10.1016/j.bmcl.2009.05.043
Mus musculus Splenocyte IC50 300.0 nM 10.1021/acs.jnatprod.0c01344
Mus musculus Splenocyte IC50 320.0 nM 10.1021/acs.jnatprod.1c01085
Mus musculus Splenocyte IC50 400.0 nM 10.1016/j.bmc.2019.06.030
Mus musculus Splenocyte IC50 400.0 nM 10.1021/acs.jmedchem.8b01430
Mus musculus Splenocyte IC50 10150.0 nM 10.1021/acs.jnatprod.1c00118
Mus musculus Splenocyte IC50 nan None 10.1021/acs.jnatprod.0c01344
Mus musculus Splenocyte Inhibition 95.0 % 10.1016/j.bmc.2009.06.043
Mus musculus Splenocyte Inhibition nan % 10.1016/j.bmc.2010.07.004
Mus musculus Splenocyte OD 0.001 None 10.1016/j.ejmech.2008.01.035
Mus musculus Splenocyte OD 0.046 None 10.1016/j.ejmech.2008.01.035
Mus musculus Splenocyte OD 0.07 None 10.1016/j.ejmech.2008.01.035
Mus musculus Splenocyte Ratio CC50/IC50 3.0 None 10.1016/j.bmc.2019.06.030
Mus musculus Splenocyte Ratio CC50/IC50 12.39 None 10.1016/j.bmcl.2009.05.043
Mus musculus Splenocyte Ratio CC50/IC50 30.0 None 10.1016/j.bmc.2019.06.030
Mus musculus Splenocyte Ratio CC50/IC50 88.0 None 10.1016/j.bmcl.2009.05.043
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Oryctolagus cuniculus Oryctolagus cuniculus Activity 24.0 % 10.1016/j.bmc.2012.07.037
Oryctolagus cuniculus Oryctolagus cuniculus Activity 25.0 % 10.1016/j.bmc.2012.07.037
Oryctolagus cuniculus Oryctolagus cuniculus Activity 32.6 % 10.1021/jm500547c
Oryctolagus cuniculus Sarcoplasmic/endoplasmic reticulum calcium ATP-ase IC50 62000.0 nM 10.1021/acs.jmedchem.9b01509
Oryctolagus cuniculus Solute carrier family 15 member 1 Activity nan None 10.1039/C5MD00575B
Plasmodium Plasmodium IC50 1700.0 nM 10.1016/j.ejmech.2020.112275
Plasmodium berghei Plasmodium berghei IC50 1.65 nM 10.1073/pnas.1118370109
Plasmodium falciparum Plasmodium falciparum IC50 0.47 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 0.56 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 0.63 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 0.71 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 0.83 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 1.26 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 95.0 nM 10.1073/pnas.1118370109
Plasmodium falciparum Plasmodium falciparum IC50 138.0 nM 10.1073/pnas.1118370109
Plasmodium falciparum Plasmodium falciparum IC50 501.19 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 630.96 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 794.33 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 1258.93 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum Potency 329.4 nM None
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1a adrenergic receptor Ki nan None None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1b adrenergic receptor Ki nan None None
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus Bile acid transporter Activity nan None 10.1152/ajpgi.1998.274.2.g370
Rattus norvegicus Bile salt export pump IC50 600.0 nM 10.1124/dmd.111.040758
Rattus norvegicus Bile salt export pump Ki 300.0 nM 10.1016/s0016-5085(00)70224-1
Rattus norvegicus Canalicular multispecific organic anion transporter 1 Ki 1960.0 nM 10.2133/dmpk.17.23
Rattus norvegicus Canalicular multispecific organic anion transporter 1 Ki 10000.0 nM 10.1002/hep.510300220
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Cyclophilin A Relative IC50 1.0 None 10.1016/S0960-894X(01)80127-X
Rattus norvegicus GABA receptor alpha-1 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Liver IC50 100.0 nM 10.1002/hep.27206
Rattus norvegicus Multidrug resistance protein 1a Activity nan None 10.1007/s004240050829
Rattus norvegicus Multidrug resistance protein 1a Activity nan None 10.1152/ajprenal.1996.270.5.f756
Rattus norvegicus Multidrug resistance protein 1a Activity nan None None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Plasma Fu 0.068 None 10.1021/jm901371v
Rattus norvegicus Plasma PPB 99.6 % 10.1128/aac.00660-09
Rattus norvegicus Rattus norvegicus Activity 9.2 % 10.1128/aac.01324-07
Rattus norvegicus Rattus norvegicus Activity 23.1 % 10.1128/aac.01324-07
Rattus norvegicus Rattus norvegicus Activity 33.6 % 10.1128/aac.01324-07
Rattus norvegicus Rattus norvegicus Activity 85.1 % 10.1021/acs.jmedchem.0c01246
Rattus norvegicus Rattus norvegicus Activity 100.0 % 10.1016/0960-894X(95)00487-E
Rattus norvegicus Rattus norvegicus Activity 100.0 mg kg-1 10.1021/np2000528
Rattus norvegicus Rattus norvegicus ALB 27000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 28000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 29000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 30000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 31000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 32000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 33700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 34000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 35300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 36000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 36700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 37400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 37700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 38000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 39000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 39300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 39400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 39700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 40000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 40300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 40700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALBGLOB 1.1 None 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALBGLOB 1.2 None 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALBGLOB 1.3 None 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 232.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 254.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 318.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 328.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 357.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 376.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 378.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 381.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 382.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 384.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 403.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 412.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 424.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 426.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 438.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 440.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 507.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 528.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 860.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 986.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1397.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1457.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1497.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1499.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1508.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1525.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1551.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1578.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1579.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1611.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1622.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1626.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1688.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1696.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1758.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1761.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1779.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1780.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1784.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1797.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1804.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1820.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1827.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1873.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1890.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1961.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1972.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1974.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 2175.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 17.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 18.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 21.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 22.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 28.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 28.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 31.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 32.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 32.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 33.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 33.2 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 33.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 34.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 34.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 34.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 35.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 35.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 36.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 37.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 37.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 37.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 38.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 39.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 39.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 40.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 40.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 41.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 41.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 42.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 42.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 43.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 43.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 44.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 44.56 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 44.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 45.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 45.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 46.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 47.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 48.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 48.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 48.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 54.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 56.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 75.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 75.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus APTT 20.5 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 21.1 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 21.5 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 21.9 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 22.1 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 22.3 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 22.6 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 22.7 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 22.8 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 22.9 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 23.0 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 23.1 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 23.3 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 23.4 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 23.9 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 24.0 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 24.3 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 24.6 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 26.3 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 28.0 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 29.9 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 30.5 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 53.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 55.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 55.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 56.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 57.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 59.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 60.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 61.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 61.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 61.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 61.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 62.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 62.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 62.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 63.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 63.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 64.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 65.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 65.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 66.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 66.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 66.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 67.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 71.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 71.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 72.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 72.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 74.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 74.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 75.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 75.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 75.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 76.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 76.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 76.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 77.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 77.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 78.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 78.6 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 81.89 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 83.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 83.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 89.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 101.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 111.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AUC 13800.0 ng.hr.mL-1 10.1021/acs.jmedchem.5b00128
Rattus norvegicus Rattus norvegicus AUC 476000.0 ng.hr.mL-1 10.1021/acs.jmedchem.5b00128
Rattus norvegicus Rattus norvegicus BASO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.1 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.15 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.19 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.27 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.3 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.35 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.43 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BASOLE 0.32 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.38 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.42 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 1.3 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 1.4 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 1.77 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 1.78 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 1.87 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 1.93 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 2.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 2.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 3.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILDIR 0.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.02 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.08 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.1 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.22 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.26 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.32 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.34 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.36 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.42 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.46 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.48 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.52 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.72 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.74 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.96 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 1.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 3.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.02 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.04 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.06 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.12 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.14 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.18 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.22 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.26 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.3 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.38 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.4 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.56 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.6 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.68 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.72 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.78 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.82 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.86 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.94 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.96 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.98 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 1.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 1.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.4 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 3.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 3.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 3.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 4.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 4.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 4.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 5.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 6.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 7.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 8.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 8.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 60.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 80.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 84.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 98.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 103.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 104.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 110.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 112.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 113.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 114.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 118.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 122.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 128.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 130.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 132.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 136.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 146.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 153.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 154.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 156.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 158.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 160.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 162.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 168.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 170.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 176.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 178.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 183.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 190.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 190.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 194.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 196.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 203.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 220.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 226.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 226.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 231.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 260.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 264.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 273.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 280.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 390.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 104.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 105.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 106.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 107.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 108.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 109.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 110.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 111.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 112.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHLORIDE 98.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 99.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 102.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 102.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 103.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 103.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 104.6 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 104.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 106.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 106.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 107.89 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 108.4 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 108.8 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 110.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 576.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 616.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 620.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 630.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 633.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 652.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 660.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 662.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 688.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 696.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 700.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 706.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 710.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 714.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 718.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 724.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 736.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 743.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 748.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 754.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 756.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 762.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 770.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 772.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 773.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 776.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 780.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 781.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 786.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 786.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 794.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 795.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 796.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 802.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 806.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 812.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 826.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 840.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 848.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 850.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 856.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 860.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 878.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 966.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 188.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 194.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 196.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 199.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 199.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 199.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 200.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 209.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 222.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 224.8 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 239.4 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 251.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 259.11 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 277.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 279.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 373.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 473.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 582.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Cl 102.2 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 102.6 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 103.0 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 103.6 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 103.8 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 104.4 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 104.8 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 105.0 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 105.2 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 105.4 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 105.6 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 105.8 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 106.0 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 106.2 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 106.6 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 107.0 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 107.4 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CL 3.5 mL.min-1.kg-1 10.1021/acs.jmedchem.5b00128
Rattus norvegicus Rattus norvegicus Cmax 1197.38 nM 10.1021/acs.jmedchem.5b00128
Rattus norvegicus Rattus norvegicus CO2 24330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 25000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 28670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 31670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 32670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 35000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 36000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 36670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 37000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 39330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 40670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 41670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 43000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 44670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 0.8 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CREAT 1.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CREAT 1.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CREAT 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.9 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 3.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CREAT 3.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 3.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 3.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 3.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 4.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 5.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus deltaA 0.18 None 10.1128/aac.01324-07
Rattus norvegicus Rattus norvegicus ED100 15.0 mg kg-1 10.1021/jm00008a001
Rattus norvegicus Rattus norvegicus ED50 0.7 mg.kg-1 10.1021/jm00008a001
Rattus norvegicus Rattus norvegicus ED50 3.4 mg.kg-1 10.1021/jm00008a001
Rattus norvegicus Rattus norvegicus EOS 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.015 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.0233 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.0333 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.0433 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.06 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.0667 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.1 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.12 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 40.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 52.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus EOSLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.1 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus EOSLE 0.27 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.3 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus EOSLE 0.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.54 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.57 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.58 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus EOSLE 0.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.7 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus EOSLE 0.8 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 1.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus EOSLE 1.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus F 23.0 % 10.1021/ml5002823
Rattus norvegicus Rattus norvegicus F 24.0 % 10.1039/C1MD00093D
Rattus norvegicus Rattus norvegicus F 29.0 % 10.1016/j.bmc.2017.08.031
Rattus norvegicus Rattus norvegicus F 29.0 % 10.1021/acs.jmedchem.5b00128
Rattus norvegicus Rattus norvegicus F 43.7 % 10.1021/ml500239m
Rattus norvegicus Rattus norvegicus Fabs 26.0 % 10.1039/C1MD00093D
Rattus norvegicus Rattus norvegicus FIBRINO 2790.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2844.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2854.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2888.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2950.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2952.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2980.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2984.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3002.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3016.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3042.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3064.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3072.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3090.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3096.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3108.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3126.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3128.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3130.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3136.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3142.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3182.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3210.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3226.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3236.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3348.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3420.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3480.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 1.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 1.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 1.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 1.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 1.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 2.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 2.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 2.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 2.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1256.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1370.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1406.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1486.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1583.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1584.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1613.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1620.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1630.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1672.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1676.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1726.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1743.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1764.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1786.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1790.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1796.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1800.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1810.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1836.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1853.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1856.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1858.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1868.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1894.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1900.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1918.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1934.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1948.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1975.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1983.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1984.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1986.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 2000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 2020.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 2024.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 2088.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 2130.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 2240.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 2320.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 2330.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 2450.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 2674.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 2710.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 3246.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 3908.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 31.63 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.2 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 35.2 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 35.6 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 37.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 37.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 37.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 37.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 37.9 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 38.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 38.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 38.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 38.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 38.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 38.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 38.9 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 39.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 39.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 39.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 39.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 39.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 40.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 40.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 40.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 40.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 40.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 41.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 41.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 41.27 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 41.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 41.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 41.9 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 42.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 42.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 43.77 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 44.87 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 44.93 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 46.36 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 46.4 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 46.6 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 46.94 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 48.38 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 48.44 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 123700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 127000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 128000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 129000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 129300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 130000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 131000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 132000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 133000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 134000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 135000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 135700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 136000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 137300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 137700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 140000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 140700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 141300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 142000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 143000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 144000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 145000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 146000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 147300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 148000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 149000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 150000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 154000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 155300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 159100.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 163000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 163400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ID50 2.8 mg.kg-1 10.1016/s0960-894x(97)10188-3
Rattus norvegicus Rattus norvegicus ID50 2.8 mg.kg-1 10.1021/jm000173z
Rattus norvegicus Rattus norvegicus ID50 30.0 mg.kg-1 10.1016/s0960-894x(97)10188-3
Rattus norvegicus Rattus norvegicus ID50 30.0 mg.kg-1 10.1021/jm000173z
Rattus norvegicus Rattus norvegicus ID80 30.0 mg kg-1 10.1021/jm000173z
Rattus norvegicus Rattus norvegicus Inhibition 93.0 % 10.1021/acsmedchemlett.6b00119
Rattus norvegicus Rattus norvegicus LDH 47.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 52.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 60.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 75.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 78.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 80.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 92.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 95.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 99.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 116.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 128.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 140.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 149.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 152.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 155.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 159.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 161.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 162.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 164.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 166.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 175.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 176.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 176.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 178.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 187.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 191.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 193.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 194.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 195.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 199.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 201.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 204.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 205.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 209.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 213.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 215.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 217.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 219.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 223.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 232.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 234.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 241.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 276.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 292.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 308.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LIPASE 7.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 10.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 10.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 22.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 23.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 26.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 37.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 6.53 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 6.89 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 8.51 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 10.47 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 10.65 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 11.86 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 11.97 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 14.14 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 6676.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 8183.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 8222.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 8734.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 9105.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 13552.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 71.55 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 72.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 73.53 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 75.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 76.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 76.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 76.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 77.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 77.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 78.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 78.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 78.73 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 79.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 79.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 79.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 79.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 80.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 80.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 81.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 81.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 81.52 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 81.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 82.3 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 82.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 82.56 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 83.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 83.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 84.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 84.4 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 84.97 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 85.12 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 85.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 87.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 87.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 88.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 89.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 90.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 17.8 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 18.51 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 18.7 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 18.95 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 19.0 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 19.2 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 19.8 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 19.88 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 20.0 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.2 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.26 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 20.3 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.33 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 20.4 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.5 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.58 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 20.6 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.8 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.93 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 21.1 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.13 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 21.2 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.2 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 21.27 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 21.3 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.4 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.5 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.6 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.63 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 21.7 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.97 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.17 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.2 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.73 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.47 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.57 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 25.0 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 33.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.9 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 34.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 34.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 34.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 34.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 34.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 34.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 34.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 34.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 35.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 35.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 35.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 318000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 324200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 327700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 328900.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 329000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 331300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 334700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 335500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 335700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 336300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 337400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 343700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 370300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 381000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 386700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 390300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 390700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 52.4 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 52.8 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 54.3 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 55.3 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 56.27 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 56.4 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 56.6 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 58.3 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 58.6 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 58.7 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 59.17 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 59.5 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 60.1 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 60.2 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 60.5 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 60.8 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 60.9 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 61.27 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.28 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.5 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 61.6 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 61.9 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 62.2 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 62.4 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 62.5 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 62.5 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.6 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.7 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 62.93 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.0 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 63.3 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 63.4 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 63.5 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 63.7 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 63.8 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 63.83 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.93 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.0 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 64.33 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.5 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 64.68 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.8 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 65.2 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 65.4 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.12 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.16 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.23 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.37 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.43 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.49 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.54 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.78 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 67.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 98.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 155.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 193.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 549.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.44 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.63 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.9 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.97 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 2.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.16 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 2.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 2.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 2.73 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.77 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 2.84 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 3.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 3.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 3.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 3.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 3.54 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 3.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 3.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 3.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 3.8 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 4.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 4.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 4.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 4.6 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 5.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 5.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 5.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 5.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 6.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 7.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MST 7.3 day 10.1016/0960-894X(95)00126-E
Rattus norvegicus Rattus norvegicus MST 7.6 day 10.1021/jm960391l
Rattus norvegicus Rattus norvegicus MST 8.0 day 10.1021/jm000173z
Rattus norvegicus Rattus norvegicus MST 8.5 day 10.1021/jm960391l
Rattus norvegicus Rattus norvegicus MST 10.3 day 10.1021/jm960391l
Rattus norvegicus Rattus norvegicus MST 10.8 day 10.1016/0960-894X(95)00126-E
Rattus norvegicus Rattus norvegicus MST 10.8 day 10.1021/jm000173z
Rattus norvegicus Rattus norvegicus MST 10.8 day 10.1021/jm960391l
Rattus norvegicus Rattus norvegicus MST 13.5 day 10.1021/jm960391l
Rattus norvegicus Rattus norvegicus MST 15.0 day 10.1021/jm000173z
Rattus norvegicus Rattus norvegicus MST 15.2 day 10.1016/0960-894X(95)00126-E
Rattus norvegicus Rattus norvegicus MST 15.2 day 10.1021/jm960391l
Rattus norvegicus Rattus norvegicus MST 19.2 day 10.1016/0960-894X(95)00126-E
Rattus norvegicus Rattus norvegicus MST 19.4 day 10.1021/jm960391l
Rattus norvegicus Rattus norvegicus MST 19.8 day 10.1021/jm000173z
Rattus norvegicus Rattus norvegicus MST 20.5 day 10.1021/jm960391l
Rattus norvegicus Rattus norvegicus MST nan None 10.1016/0960-894X(95)00126-E
Rattus norvegicus Rattus norvegicus MST nan None 10.1021/jm000173z
Rattus norvegicus Rattus norvegicus MST nan None 10.1021/jm960391l
Rattus norvegicus Rattus norvegicus NEUTLE 5.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 6.27 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 9.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 10.27 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 11.1 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 11.28 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 11.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 11.54 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 11.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 12.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 12.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 12.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 12.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 12.73 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 12.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 12.97 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 13.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 13.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 13.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 13.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 13.88 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 14.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 14.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 15.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 15.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 15.4 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 15.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 16.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 16.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 16.79 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 17.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 17.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 17.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 18.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 18.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 18.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 19.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 19.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 19.7 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 20.6 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 21.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTSG 623.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 718.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1020.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1034.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1249.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 2124.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 67.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 70.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 71.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 73.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 74.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 76.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 77.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 81.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 84.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 85.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 86.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 87.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 88.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 89.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 93.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 94.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 97.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 98.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 99.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 99.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 100.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 101.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 102.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 102.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 105.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 105.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 105.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 106.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 106.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 107.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 108.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 111.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 112.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 116.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 118.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 120.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 122.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 131.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 134.4 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOSLPD 1242.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1310.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1360.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1362.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1376.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1398.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1418.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1432.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1448.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1450.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1454.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1472.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1492.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1494.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1504.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1506.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1514.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1520.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1574.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1590.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1592.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1616.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1624.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1654.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1672.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1684.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1698.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1722.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1776.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1876.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 793670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 859000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 896000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 920000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 937000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1014330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1032000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1070000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1080330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1099000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1123000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1130330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1141000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1145000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1153000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1155000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1167000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1167330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1186000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1190000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1196000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1204000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1211000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1215670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1216000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1226000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1226000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1229000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1233000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1235000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1237000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1242000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1250000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1258000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1268000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1269330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1280000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1281000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1291670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1305000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1326000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1326400.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1331500.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1371670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1415330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1423890.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1531200.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 3.6 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 3.8 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 3.9 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.0 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.1 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.2 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.3 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.4 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.5 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.6 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.7 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.8 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.9 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.97 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.24 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.37 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.38 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.54 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.6 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.7 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.73 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.92 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.13 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.53 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.57 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.58 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.8 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.83 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 7.03 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 50300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 51300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 51700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 52000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 53000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 54000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 54700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 55000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 55000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 55700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 56000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 56500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 57000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 57000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 58400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 58700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 59000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 60000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 60600.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 62300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 63000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 64200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 65000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 65700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 66000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 66400.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PT 15.4 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 15.5 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 15.6 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 15.7 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 15.9 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.0 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.1 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.2 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.3 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.4 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.6 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.7 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 17.2 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 17.4 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 18.1 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 18.2 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 5030000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5190000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5630000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5820000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5958000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 5982000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6022000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6070000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6086000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6112000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6130000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6132000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6138000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6156000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6180000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6184000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6196000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6212000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6220000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6250000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6268000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6280000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6284000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6290000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6318000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6380000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6410000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6470000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6576000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6610000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6620000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6706000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6736000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6770000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6800000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6930000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7014000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 7070000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7190000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7260000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7282000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 7300000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7352000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 7410000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7560000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7570000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 7570000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7834000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 8060000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 8590000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Reduction 51.0 % 10.1016/S0960-894X(00)80359-5
Rattus norvegicus Rattus norvegicus Reduction 68.0 % 10.1016/S0960-894X(00)80359-5
Rattus norvegicus Rattus norvegicus Reduction 77.0 % 10.1016/S0960-894X(00)80359-5
Rattus norvegicus Rattus norvegicus Reduction 100.0 % 10.1016/S0960-894X(00)80359-5
Rattus norvegicus Rattus norvegicus RETIRBC 1.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 1.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 2.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 2.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 2.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 2.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 3.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 3.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 3.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 4.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 4.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 4.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 4.9 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 5.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 5.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 5.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 6.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 6.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 6.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 6.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 6.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 7.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 7.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 7.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 7.9 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 8.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 138.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 138.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 138.63 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 139.6 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 140.4 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 140.8 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 141.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 141.03 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 141.2 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 141.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 141.4 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 141.6 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 141.8 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 142.1 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.2 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 142.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.4 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 142.8 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 143.0 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 143.2 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 143.3 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.4 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 143.6 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 143.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.8 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 144.2 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 144.4 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 145.3 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 145.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 145.77 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 146.8 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 148.2 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 148.6 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 152.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus T1/2 6.0 hr 10.1021/acs.jmedchem.5b00128
Rattus norvegicus Rattus norvegicus TERMBW 194.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 200.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 202.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 202.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 203.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 203.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 205.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 205.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 205.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 206.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 207.3 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 208.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 210.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 211.3 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 212.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 214.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 215.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 217.6 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 217.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 224.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 242.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 246.3 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 257.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 261.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 287.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 299.6 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 302.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 323.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 361.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 363.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 401.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TIME 175.2 hr 10.1021/np2000528
Rattus norvegicus Rattus norvegicus TIME 259.2 hr 10.1021/np2000528
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus TRIG 346.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 390.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 474.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 498.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 510.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 524.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 554.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 556.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 602.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 676.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 682.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 692.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 718.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 770.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 810.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 842.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 866.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 884.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 934.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1008.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1046.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1052.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1120.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1122.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1130.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1198.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1264.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1398.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1402.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1406.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1454.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 2186.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus URATE 1.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 2.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 3.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 5.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 6.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 7.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 9.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 9.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 10.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 12.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 14.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 14.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 14.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Vdss 1.2 L.kg-1 10.1021/acs.jmedchem.5b00128
Rattus norvegicus Rattus norvegicus WBC 6400.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 7280.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7370.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 7430.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7500.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7660.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 7710.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7830.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7950.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7980.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8200.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8340.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8380.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 8410.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8460.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8690.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 8820.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8980.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9130.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 9190.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9340.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9400.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9430.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 9480.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9700.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9870.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9870.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 9930.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9970.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 10090.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 10200.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 10260.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 10330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 10440.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 10530.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 10630.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 10930.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 11320.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 11550.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 11990.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 12010.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 12500.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13040.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13340.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 14510.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 16150.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 16270.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 16880.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 17870.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WEIGHT 0.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.2 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.3 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.2 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.6 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 3.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 8.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 8.2 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 8.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 8.6 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 8.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 8.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 9.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 9.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 9.3 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 9.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 9.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 10.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 10.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 10.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 11.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 12.2 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 12.3 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 12.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 13.3 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 13.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 14.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 15.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 17.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 17.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 nan None None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki nan None None
Rattus norvegicus Solute carrier family 22 member 6 Activity nan None 10.1074/jbc.272.48.30088
Rattus norvegicus Solute carrier organic anion transporter family member 1A1 Activity 27.6 % 10.1023/a:1014264614637
Rattus norvegicus Solute carrier organic anion transporter family member 1A4 Activity 27.4 % 10.1023/a:1014264614637
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Voltage-gated N-type calcium channel alpha-1B subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Saccharomyces cerevisiae Saccharomyces cerevisiae Potency 35481.3 nM None
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.07198 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 5820.0 nM 10.1101/2020.03.20.999730
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 6606.93 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 6610.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 50100.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 50118.72 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition index -0.1003 None 10.1101/2020.04.03.023846
Severe acute respiratory syndrome-related coronavirus SARS-CoV IC50 8300.0 nM 10.1128/aac.01324-07
Simian immunodeficiency virus Simian immunodeficiency virus Activity 10.0 % 10.1016/j.bmc.2009.02.051
Simian immunodeficiency virus Simian immunodeficiency virus EC50 nan None 10.1016/j.bmc.2009.02.051
Tenuivirus oryzaclavatae Rice stripe virus IC50 8300.0 nM 10.1128/aac.01324-07
Tolypocladium inflatum Tolypocladium inflatum IC50 5.0 nM 10.1021/jm00117a022
Trichophyton mentagrophytes Trichophyton mentagrophytes Activity nan None 10.1128/aac.00492-07
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC 1.0 ug.mL-1 10.1128/aac.00492-07
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC 2.0 ug.mL-1 10.1128/aac.00492-07
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC80 2.0 ug.mL-1 10.1128/aac.00492-07
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC80 8.0 ug.mL-1 10.1128/aac.00492-07
Trypanosoma brucei brucei Trypanosoma brucei brucei IC50 1.14 nM 10.1021/jm4004279
Trypanosoma cruzi Trypanosoma cruzi EC50 7190.0 nM 10.1016/j.bmcl.2004.07.003
Trypanosoma cruzi Trypanosoma cruzi IC50 5390.0 nM 10.1016/j.bmcl.2004.07.003
Vaccinia virus Vaccinia virus IC50 8300.0 nM 10.1128/aac.01324-07
Vesicular stomatitis virus Vesicular stomatitis virus Activity nan None 10.1128/aac.00189-09
Vesicular stomatitis virus Vesicular stomatitis virus IC50 8300.0 nM 10.1128/aac.01324-07
West Nile virus West Nile virus Activity nan None 10.1128/aac.00189-09
West Nile virus West Nile virus IC50 8000.0 nM 10.1128/aac.00189-09
West Nile virus West Nile virus Inhibition 2.0 % 10.1128/aac.00189-09
West Nile virus West Nile virus Inhibition 4.0 % 10.1128/aac.00189-09
West Nile virus West Nile virus Inhibition 10.0 % 10.1128/aac.00189-09
West Nile virus West Nile virus Inhibition 18.0 % 10.1128/aac.00189-09
West Nile virus West Nile virus Inhibition 70.0 % 10.1128/aac.00189-09
West Nile virus West Nile virus Inhibition nan % 10.1128/aac.00189-09
Yellow fever virus Yellow fever virus Activity nan None 10.1128/aac.00189-09
Yellow fever virus Yellow fever virus IC50 16600.0 nM 10.1128/aac.01324-07
Yellow fever virus Yellow fever virus Inhibition 70.0 % 10.1128/aac.00189-09
Yellow fever virus Yellow fever virus Inhibition nan % 10.1128/aac.00189-09
None ADMET Activity 20.0 % 10.1021/acs.jmedchem.5b01064
None ADMET Activity 48.0 None 10.1016/j.bmcl.2009.05.054
None ADMET Activity 80.0 % 10.1128/aac.00189-09
None ADMET Activity 87.0 % 10.1021/acs.jmedchem.1c00211
None ADMET Activity 1800.0 mg 10.1021/acs.jmedchem.0c00524
None ADMET Activity nan None 10.1021/acs.jmedchem.5b01064
None ADMET Activity nan None 10.1021/acs.jmedchem.5b01801
None ADMET Activity nan None 10.1021/acsmedchemlett.5b00451
None ADMET Activity nan None 10.1021/jm5004123
None ADMET Activity nan None 10.1128/aac.00660-09
None ADMET AUC 2900.0 ng.hr.mL-1 10.1021/acs.jmedchem.1c00211
None ADMET BPR 3.12 None 10.1021/acs.jmedchem.1c00211
None ADMET CC50 880.0 nM 10.1016/j.bmcl.2009.05.043
None ADMET CC50 1350.0 nM 10.1016/j.bmc.2006.10.034
None ADMET CC50 4400.0 nM 10.1039/C1MD00227A
None ADMET CC50 6000.0 nM 10.1128/aac.01534-07
None ADMET CC50 7000.0 nM 10.1128/aac.01534-07
None ADMET CC50 10100.0 nM 10.1016/j.bmcl.2012.03.080
None ADMET CC50 13780.0 nM 10.1016/j.bmc.2012.01.023
None ADMET CC50 14960.0 nM 10.1007/s00044-013-0561-0
None ADMET CC50 15820.0 nM 10.1016/j.ejmech.2010.10.034
None ADMET CC50 24000.0 nM 10.1128/aac.01534-07
None ADMET CC50 174240.0 nM 10.1016/j.bmc.2012.05.055
None ADMET CC50 178260.0 nM 10.1016/j.ejmech.2015.12.020
None ADMET CL 7.5 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET CL 117.0 mL.min-1.kg-1 10.1021/acs.jmedchem.1c00211
None ADMET CL 77000.0 mL.min-1.g-1 10.1128/aac.00660-09
None ADMET Cmax 449.02 nM 10.1021/acs.jmedchem.1c00211
None ADMET Drug recovery 52.0 % 10.1021/acs.jmedchem.1c00211
None ADMET Drug recovery 58.0 % 10.1021/acs.jmedchem.1c00211
None ADMET Drug recovery 68.0 % 10.1021/acs.jmedchem.1c00211
None ADMET Drug uptake nan None 10.1021/jm4007577
None ADMET F 20.0 % 10.1021/acs.jmedchem.1c00211
None ADMET Fu 0.005 None 10.1021/acs.jmedchem.8b00802
None ADMET GI50 8630.0 nM 10.1016/j.ejmech.2016.03.067
None ADMET IC50 0.01 ug.mL-1 10.1021/jm301518v
None ADMET IC50 2.75 ug.mL-1 10.1021/jm960023h
None ADMET IC50 10.0 nM 10.1016/j.bmcl.2015.11.002
None ADMET IC50 40.0 nM 10.1016/j.bmcl.2015.11.002
None ADMET IC50 56.0 nM 10.1128/aac.01324-07
None ADMET IC50 2900.0 nM 10.1124/dmd.112.050260
None ADMET IC50 5810.0 nM 10.1016/j.bmcl.2010.09.036
None ADMET IC50 8970.0 nM 10.1016/j.bmcl.2004.04.092
None ADMET IC90 18750.0 nM 10.1016/j.bmcl.2010.09.036
None ADMET Inhibition 8.7 % 10.1016/j.bmc.2009.06.043
None ADMET Inhibition 98.0 % 10.1124/dmd.112.050260
None ADMET log Pe -6.2 None 10.1021/acs.jmedchem.6b00222
None ADMET Log Phep 1.4 None 10.1021/jm00076a002
None ADMET MRT 7.3 hr 10.1124/dmd.108.020479
None ADMET OD 0.51 None 10.1016/j.bmc.2012.03.064
None ADMET Papp 1.0 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 1.4 10'-6 cm/s 10.1021/acs.jmedchem.8b01259
None ADMET Papp 2.5 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 2.57 ucm/s 10.1124/dmd.111.043778
None ADMET Papp 5.0 ucm/s 10.1021/ml5002823
None ADMET Papp 5.1 ucm/s 10.1021/ml500239m
None ADMET Papp 5.8 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 8.1 ucm/s 10.1124/dmd.110.034629
None ADMET permeability 1.51 10^-6 cm/s 10.1021/acs.jmedchem.1c00211
None ADMET permeability 1.61 10'-4 cm/s 10.1021/jm901846t
None ADMET permeability 1.97 10^-6 cm/s 10.1021/acs.jmedchem.1c00211
None ADMET permeability 2.5 10^-6 cm/s 10.1021/acs.jmedchem.1c00211
None ADMET permeability 3.3 10^-6 cm/s 10.1021/acs.jmedchem.1c00580
None ADMET permeability 3.5 10'-6 cm/s 10.1016/j.bmc.2009.12.010
None ADMET permeability 4.51 10^-6 cm/s 10.1021/acs.jmedchem.1c00211
None ADMET permeability 5.6 10'-6 cm/s 10.1021/acsmedchemlett.9b00149
None ADMET permeability 9.8 10^-6 cm/s 10.1021/acs.jmedchem.1c00580
None ADMET permeability 62.0 % 10.1021/jm070836d
None ADMET Ratio -41.0 None 10.1124/dmd.110.034629
None ADMET Ratio 0.7 None 10.1002/j.1552-4604.1990.tb01868.x
None ADMET Ratio 0.8 None 10.1002/j.1552-4604.1990.tb01868.x
None ADMET Ratio 0.99 None 10.1002/j.1552-4604.1990.tb01868.x
None ADMET Ratio 1.05 None 10.1002/j.1552-4604.1990.tb01868.x
None ADMET Ratio 1.24 None 10.1002/j.1552-4604.1990.tb01868.x
None ADMET Ratio 1.3 None 10.1002/j.1552-4604.1994.tb03967.x
None ADMET Ratio 1.31 None 10.1002/j.1552-4604.1990.tb01868.x
None ADMET Ratio 1.6 None 10.1124/dmd.111.043778
None ADMET Ratio 1.7 None 10.1002/j.1552-4604.1994.tb03967.x
None ADMET Ratio 1.78 None 10.1002/j.1552-4604.1990.tb01868.x
None ADMET Ratio 2.0 None 10.1002/j.1552-4604.1990.tb01868.x
None ADMET Ratio 2.6 None 10.1002/j.1552-4604.1994.tb03967.x
None ADMET Ratio 3.0 None 10.1021/acs.jmedchem.1c00211
None ADMET Ratio 3.2 None 10.1124/dmd.110.034629
None ADMET Ratio 5.6 None 10.1124/dmd.110.034629
None ADMET Ratio 42.0 None 10.1124/dmd.110.034629
None ADMET Ratio 144.0 None 10.1124/dmd.110.034629
None ADMET Ratio CC50/IC50 9.9 None 10.1021/acs.jnatprod.2c00204
None ADMET Ratio CC50/IC50 249.6 None 10.1021/acs.jnatprod.2c00204
None ADMET Ratio IC50/EC50 1059.4 None 10.1021/jm400930e
None ADMET Selectivity index 8.59 None 10.1101/2020.03.20.999730
None ADMET Selectivity Index 934.0 None 10.1016/j.ejmech.2021.113795
None ADMET T1/2 0.1833 hr 10.1128/aac.00660-09
None ADMET T1/2 4.6 hr 10.1021/acs.jmedchem.1c00211
None ADMET T1/2 7.3 hr 10.1124/dmd.108.020479
None ADMET TC50 8.3 uM 10.1128/aac.01324-07
None ADMET TC50 10.0 uM 10.1128/aac.01324-07
None ADMET TC50 42.0 uM 10.1016/j.bmcl.2009.05.054
None ADMET TC50 75.0 uM 10.1016/j.bmcl.2009.05.054
None ADMET TC50 nan None 10.1128/aac.01324-07
None ADMET TI 6.0 None 10.1016/j.ejmech.2016.03.067
None ADMET Tmax 1.0 hr 10.1021/acs.jmedchem.1c00211
None ADMET Vd 46.7 L.kg-1 10.1021/acs.jmedchem.1c00211
None ADMET Vdss 3.3 L.kg-1 10.1124/dmd.108.020479
None B-cell IC50 159.0 nM 10.1016/j.bmc.2006.10.034
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx1000865
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity Hepatotoxicity nan None 10.1124/dmd.110.035113
None Hepatotoxicity HepSE_bilirubinemia 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LTKB_BD DILI severity score 2.0 None 10.1016/j.drudis.2011.05.007
None Lymphocyte CC50 43200.0 nM 10.1016/j.bmcl.2017.12.045
None Lymphocyte EC50 60.0 nM 10.1021/jm500223x
None Lymphocyte IC50 0.2 ug.mL-1 10.1021/np50055a001
None Lymphocyte IC50 54.0 nM 10.1016/j.bmcl.2009.12.098
None Lymphocyte IC50 54.0 nM 10.1021/jm101254z
None Lymphocyte IC50 89.0 nM 10.1021/ml4004809
None MDR IC50 2800.0 nM 10.1021/jm201121b
None Molecular identity unknown PPB 91.0 % 10.1002/j.1552-4604.1994.tb03967.x
None Neutrophil IC50 0.047 nM 10.1016/j.bmc.2009.03.035
None NON-PROTEIN TARGET Activity nan None 10.1016/0960-894X(95)00281-W
None NON-PROTEIN TARGET Activity nan None 10.1016/s0960-894x(97)10221-9
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00189-09
None NON-PROTEIN TARGET Bronchoalveolar lavages 62.0 None 10.1021/jm990615a
None NON-PROTEIN TARGET Bronchoalveolar lavages 68.0 None 10.1021/jm990615a
None NON-PROTEIN TARGET Bronchoalveolar lavages 92.0 None 10.1021/jm990615a
None NON-PROTEIN TARGET Bronchoalveolar lavages 137.0 None 10.1021/jm990615a
None NON-PROTEIN TARGET Cytotoxicity 2.75 ug ml-1 10.1016/S0960-894X(97)10072-5
None NON-PROTEIN TARGET Fu 0.068 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 25.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 1.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 72.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 94.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET IC50 0.04 ug.mL-1 10.1021/np010152n
None NON-PROTEIN TARGET IC50 0.04 ug.mL-1 10.1021/np0302201
None NON-PROTEIN TARGET IC50 0.07 ug.mL-1 10.1021/np010152n
None NON-PROTEIN TARGET IC50 0.07 ug.mL-1 10.1021/np0302201
None NON-PROTEIN TARGET IC50 11.0 nM 10.1021/jm300630p
None NON-PROTEIN TARGET IC50 12.0 nM 10.1021/np0100237
None NON-PROTEIN TARGET IC50 14.0 nM 10.1021/np2000528
None NON-PROTEIN TARGET IC50 32.0 nM 10.1126/science.1087061
None NON-PROTEIN TARGET IC50 60.0 nM 10.1007/s00044-013-0561-0
None NON-PROTEIN TARGET IC50 60.0 nM 10.1016/j.ejmech.2010.10.034
None NON-PROTEIN TARGET IC50 70.0 nM 10.1016/j.bmc.2012.01.023
None NON-PROTEIN TARGET IC50 70.0 nM 10.1016/j.bmcl.2012.03.080
None NON-PROTEIN TARGET IC50 74.0 nM 10.1126/science.1087061
None NON-PROTEIN TARGET IC50 100.0 nM 10.1016/j.bmcl.2014.12.007
None NON-PROTEIN TARGET IC50 184.0 nM 10.1021/jm048979c
None NON-PROTEIN TARGET IC50 340.0 nM 10.1021/np010217m
None NON-PROTEIN TARGET IC50 550.0 nM 10.1016/j.bmcl.2009.05.054
None NON-PROTEIN TARGET IC50 700.0 nM 10.1021/jm501676v
None NON-PROTEIN TARGET IC50 700.0 nM 10.1128/aac.01324-07
None NON-PROTEIN TARGET IC50 1000.0 nM 10.1021/jm010126m
None NON-PROTEIN TARGET IC50 1100.0 nM 10.1021/jm010126m
None NON-PROTEIN TARGET IC50 2120.0 nM 10.1016/j.bmc.2012.05.055
None NON-PROTEIN TARGET IC50 2800.0 nM 10.1021/jm400930e
None NON-PROTEIN TARGET IC50 6600.0 nM 10.1128/aac.01324-07
None NON-PROTEIN TARGET IC50 8300.0 nM 10.1021/jm201121b
None NON-PROTEIN TARGET IC50 8300.0 nM 10.1021/jm400930e
None NON-PROTEIN TARGET IC50 10000.0 nM 10.1126/science.1087061
None NON-PROTEIN TARGET IC50 100000.0 nM 10.1021/jm300630p
None NON-PROTEIN TARGET IC50 nan None 10.1126/science.1087061
None NON-PROTEIN TARGET Inhibition 58.3 % 10.1021/ml2000998
None NON-PROTEIN TARGET Inhibition 69.77 % 10.1016/j.bmc.2012.03.064
None NON-PROTEIN TARGET Inhibition 86.4 % 10.1016/j.bmc.2009.06.043
None NON-PROTEIN TARGET Inhibition 96.0 % 10.1016/j.bmcl.2016.09.047
None NON-PROTEIN TARGET Inhibition 101.1 % 10.1021/np500465g
None NON-PROTEIN TARGET Inhibition nan % 10.1021/jm3017893
None NON-PROTEIN TARGET Inhibition nan % 10.1021/ml4004809
None NON-PROTEIN TARGET Ratio 53.0 None 10.1016/S0960-894X(97)10072-5
None NON-PROTEIN TARGET Relative cytotoxicity 26.9 None 10.1021/jm010126m
None NON-PROTEIN TARGET Relative cytotoxicity 33.6 None 10.1021/jm010126m
None NON-PROTEIN TARGET Selectivity index 53.0 None 10.1021/jm960023h
None NON-PROTEIN TARGET Survival 97.0 % 10.1016/j.bmc.2016.08.051
None NON-PROTEIN TARGET TC50 0.3 uM 10.1128/aac.01324-07
None NON-PROTEIN TARGET TC50 4.6 uM 10.1128/aac.01324-07
None No relevant target Daq 4.0 10'-6cm2/s 10.1021/jm901846t
None No relevant target Fu 0.14 None 10.1021/acs.jmedchem.8b00802
None No relevant target LogD 3.7 None 10.1021/acs.jmedchem.8b01259
None No relevant target LogD 4.4 None 10.1039/C1MD00227A
None No relevant target LogP 1.4 None 10.1021/acs.jmedchem.1c00580
None No relevant target LogP 2.9 None 10.1021/jm021012t
None No relevant target LogP 2.92 None 10.1021/acs.jmedchem.1c00580
None No relevant target LogP 2.92 None 10.1021/jm00076a002
None No relevant target LogP 3.54 None 10.1021/jm901846t
None No relevant target LogP 14.0 None 10.1021/jm00076a002
None No relevant target Solubility 10000.0 nM 10.1021/acs.jmedchem.8b01259
None No relevant target Solubility 51000.0 nM 10.1039/C1MD00227A
None Phospholipidosis Maximum test concentration that did not exhibit cytotoxicity 6.25 uM None
None Phospholipidosis Phospholipidosis as % of positive control 0.3 % None
None T-cell Activity 0.68 % 10.1021/ml4004809
None T-cell Activity 0.71 % 10.1016/j.bmcl.2011.10.081
None T-cell Activity 1.02 % 10.1021/ml4004809
None T-cell Activity 1.94 % 10.1021/ml4004809
None T-cell Activity 2.01 % 10.1021/ml4004809
None T-cell Activity 10.8 % 10.1021/ml4004809
None T-cell Activity 10.9 % 10.1021/ml4004809
None T-cell Activity 35.14 % 10.1016/j.bmc.2009.06.043
None T-cell Activity 86.1 % 10.1021/ml4004809
None T-cell Activity 86.5 % 10.1021/ml4004809
None T-cell CC50 4500.0 nM 10.1021/acs.jnatprod.7b00017
None T-cell EC50 6.4 nM 10.1021/acs.jmedchem.6b01329
None T-cell ED50 50.0 nM 10.1016/j.bmcl.2004.06.028
None T-cell IC50 0.046 ug.mL-1 10.1021/np50055a001
None T-cell IC50 0.28 ug.mL-1 10.1021/np50055a001
None T-cell IC50 1.34 nM 10.1021/jm048979c
None T-cell IC50 1.37 nM 10.1016/j.bmc.2006.10.034
None T-cell IC50 7.0 nM 10.1016/S0960-894X(97)10005-1
None T-cell IC50 8.1 nM 10.1021/jm00008a001
None T-cell IC50 13.7 nM 10.1021/jm00008a001
None T-cell IC50 80.0 nM 10.1021/acs.jnatprod.7b00017
None T-cell IC50 100.0 nM 10.1021/acs.jnatprod.9b01167
None T-cell IC50 200.0 nM 10.1021/acs.jnatprod.8b00791
None T-cell IC50 260.0 nM 10.1016/j.bmcl.2017.12.045
None T-cell IC50 8970.0 nM 10.1016/j.bmcl.2011.10.081
None T-cell IC50 10000.0 nM 10.1126/science.1087061
None T-cell Ratio 1.0 None 10.1016/S0960-894X(01)80716-2
None T-cell Ratio CC50/IC50 8.0 None 10.1016/j.bmc.2006.10.034
None T-cell Ratio CC50/IC50 56.3 None 10.1021/acs.jnatprod.7b00017
None T-cell Ratio CC50/IC50 82.19 None 10.1016/j.bmc.2012.05.055
None T-cell Ratio CC50/IC50 196.86 None 10.1016/j.bmc.2012.01.023
None T-cell Ratio CC50/IC50 263.67 None 10.1016/j.ejmech.2010.10.034
None Unchecked Ac50 0.631 uM None
None Unchecked Ac50 3.981 uM None
None Unchecked Ac50 4.467 uM None
None Unchecked AC50 631.0 nM None
None Unchecked AC50 3981.1 nM None
None Unchecked AC50 4466.8 nM None
None Unchecked Activity 0.5 uM 10.1074/jbc.m706175200
None Unchecked Activity 0.6 uM 10.1074/jbc.m706175200
None Unchecked Activity 46.0 % 10.1016/j.ejmech.2012.12.033
None Unchecked Activity 46.0 % 10.1016/j.ejmech.2014.07.027
None Unchecked Activity 46.0 % 10.1016/j.ejmech.2017.12.045
None Unchecked Activity 81.83 % 10.1016/j.ejmech.2021.113791
None Unchecked Activity 84.2 % 10.1016/j.ejmech.2018.04.012
None Unchecked Activity 100.0 % 10.1021/acs.jmedchem.1c00580
None Unchecked Activity 100.0 % 10.1021/jm00165a018
None Unchecked Activity 224.0 % 10.1021/jm500547c
None Unchecked Activity nan None 10.1016/j.ejmech.2017.09.043
None Unchecked Activity nan None 10.1021/acs.jmedchem.0c01484
None Unchecked Activity nan None 10.1021/acs.jmedchem.5b01064
None Unchecked Activity nan None 10.1021/jm900254k
None Unchecked Activity nan None 10.1021/np400950h
None Unchecked CC50 9800.0 nM 10.1021/acs.jnatprod.0c00067
None Unchecked CC50 22120.0 nM None
None Unchecked CC50 200400.0 nM 10.1021/acs.jnatprod.8b00920
None Unchecked EC50 32.0 nM 10.1016/j.ejmech.2021.113795
None Unchecked EC50 600.0 nM 10.1021/jm010126m
None Unchecked EC50 700.0 nM 10.1021/jm010126m
None Unchecked EC50 25200.0 nM 10.1016/j.bmcl.2008.05.055
None Unchecked EC50 80000.0 nM 10.1016/j.bmc.2008.01.055
None Unchecked EC50 80000.0 nM None
None Unchecked EC50 83680.0 nM 10.1016/j.ejmech.2018.04.012
None Unchecked FC 0.67 None 10.1016/j.ejmech.2021.113168
None Unchecked FC 5.4 None 10.1016/j.ejmech.2018.04.012
None Unchecked FC 77.4 None 10.1016/j.ejmech.2016.09.070
None Unchecked Flu intensity 4.4 None 10.1021/acs.jmedchem.6b00525
None Unchecked Flu intensity 27.0 None 10.1021/acs.jmedchem.6b00525
None Unchecked Hepatotoxicity (acute) 15.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 11.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 4.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 1e-09 None 10.1016/S0960-894X(01)80906-9
None Unchecked IC50 0.01 ug.mL-1 10.1016/0960-894X(95)00140-O
None Unchecked IC50 0.047 nM 10.1016/j.bmcl.2007.04.036
None Unchecked IC50 1.4 nM 10.1021/jm4007577
None Unchecked IC50 1.8 nM 10.1016/j.ejmech.2016.09.070
None Unchecked IC50 4.0 nM 10.1021/jm00156a014
None Unchecked IC50 5.0 nM 10.1021/jm00048a002
None Unchecked IC50 5.0 nM 10.1021/jm010066k
None Unchecked IC50 7.0 nM 10.1016/j.bmcl.2020.127545
None Unchecked IC50 7.0 nM 10.1021/acs.jmedchem.1c00631
None Unchecked IC50 10.0 nM 10.1021/jm901108b
None Unchecked IC50 14.0 nM 10.1021/jm960391l
None Unchecked IC50 14.42 nM 10.1016/j.bmcl.2004.07.003
None Unchecked IC50 20.0 nM 10.1016/j.bmcl.2019.126717
None Unchecked IC50 26.0 nM 10.1021/acs.jnatprod.0c00067
None Unchecked IC50 30.0 nM 10.1016/j.bmcl.2020.127545
None Unchecked IC50 30.0 nM 10.1021/acs.jnatprod.2c00204
None Unchecked IC50 50.0 nM 10.1016/j.bmcl.2004.09.093
None Unchecked IC50 54.0 nM 10.1016/j.bmc.2012.12.032
None Unchecked IC50 79.4 nM 10.1021/jm4007577
None Unchecked IC50 500.0 nM 10.1016/j.bmcl.2018.05.050
None Unchecked IC50 1000.0 nM 10.1016/S0960-894X(97)10005-1
None Unchecked IC50 1150.0 nM 10.1016/j.bmcl.2017.12.045
None Unchecked IC50 1300.0 nM 10.1021/acs.jnatprod.8b00920
None Unchecked IC50 10000.0 nM 10.1021/jm010822m
None Unchecked IC50 14899.0 nM None
None Unchecked IC50 19400.0 nM 10.1021/jm050169t
None Unchecked IC50 21900.0 nM 10.1021/acs.jmedchem.9b00963
None Unchecked IC50 31350.0 nM 10.1016/j.bmcl.2021.128235
None Unchecked IC50 62000.0 nM 10.1021/acs.jmedchem.9b01509
None Unchecked IC50 99290.0 nM None
None Unchecked IC50 99570.0 nM None
None Unchecked IC50 100000.0 nM 10.1016/j.bmcl.2009.05.054
None Unchecked IC50 nan nM 10.1016/j.bmcl.2004.09.093
None Unchecked IC50 nan None None
None Unchecked Inhibition 24.0 % 10.1021/acs.jmedchem.0c01236
None Unchecked Inhibition 37.0 % 10.1021/acs.jmedchem.0c01236
None Unchecked Inhibition 50.0 % 10.1021/ml1002663
None Unchecked Inhibition 75.0 % 10.1021/ml1002663
None Unchecked Inhibition 93.5 % 10.1039/D1MD00210D
None Unchecked Inhibition 96.8 % 10.1016/j.ejmech.2021.113791
None Unchecked Inhibition nan % 10.1016/j.bmcl.2012.01.107
None Unchecked Inhibition nan % 10.1016/j.ejmech.2021.113168
None Unchecked Inhibition nan % 10.1021/acs.jmedchem.5b01064
None Unchecked Inhibition nan % 10.1021/acs.jmedchem.5b01801
None Unchecked Inhibition nan % 10.1021/acs.jmedchem.6b00525
None Unchecked Inhibition nan % 10.1021/acs.jmedchem.8b00278
None Unchecked Inhibition nan % 10.1021/acs.jnatprod.1c00118
None Unchecked Inhibition nan % 10.1021/jm4007577
None Unchecked Inhibition nan % 10.1021/jm500547c
None Unchecked Inhibition nan % 10.1021/ml1002663
None Unchecked Inhibition nan % 10.1021/np2000528
None Unchecked Inhibition nan % 10.1038/nchembio873
None Unchecked Inhibition nan % 10.1128/aac.00189-09
None Unchecked Kd 6.0 nM 10.1016/S0960-894X(00)80405-9
None Unchecked Ki 2090.0 nM 10.1016/j.pharmthera.2004.10.013
None Unchecked Ki 13358.0 nM None
None Unchecked Ki nan None None
None Unchecked Potency 562.3 nM None
None Unchecked Potency 1000.0 nM None
None Unchecked Potency 2238.7 nM None
None Unchecked Potency 2511.9 nM None
None Unchecked Potency 5804.8 nM None
None Unchecked Potency 6309.6 nM None
None Unchecked Potency 15848.9 nM None
None Unchecked Potency 18356.4 nM None
None Unchecked Potency 20596.2 nM None
None Unchecked Ratio 0.009 None 10.1093/toxsci/kft176
None Unchecked Ratio 0.014 None 10.1093/toxsci/kft176
None Unchecked Ratio 0.406 None 10.1093/toxsci/kft176
None Unchecked Ratio 1.0 None 10.1016/S0960-894X(01)80716-2
None Unchecked Ratio 2.4 None 10.1021/acs.jmedchem.6b00525
None Unchecked Ratio 2.6 None 10.1021/jm501676v
None Unchecked Ratio 46.0 % 10.1016/j.ejmech.2017.09.043
None Unchecked Ratio 57.4 None 10.1021/acs.jmedchem.6b00525
None Unchecked Ratio 76.6 None 10.1021/jm201121b
None Unchecked Ratio nan None 10.1021/jm201121b
None Unchecked Ratio CC50/EC50 14.0 None 10.1039/C1MD00227A
None Unchecked Ratio CC50/EC50 nan None 10.1021/acs.jnatprod.2c00766
None Unchecked Ratio CC50/IC50 7.81 None 10.1021/acs.jnatprod.1c01085
None Unchecked Ratio CC50/IC50 38.0 None 10.1016/j.bmcl.2017.12.045
None Unchecked Ratio CC50/IC50 77.8 None 10.1021/acs.jnatprod.0c00067
None Unchecked Ratio CC50/IC50 83.33 None 10.1021/acs.jnatprod.1c01085
None Unchecked Ratio CC50/IC50 149.6 None 10.1021/acs.jnatprod.8b00920
None Unchecked Ratio CC50/IC50 154.13 None 10.1016/j.bmcl.2012.03.080
None Unchecked Ratio CC50/IC50 166.0 None 10.1016/j.bmcl.2017.12.045
None Unchecked Ratio CC50/IC50 249.33 None 10.1007/s00044-013-0561-0
None Unchecked Ratio CC50/IC50 312.73 None 10.1016/j.ejmech.2015.12.020
None Unchecked Ratio CC50/IC50 985.0 None 10.1016/j.bmc.2006.10.034
None Unchecked Ratio IC50 79.4 None 10.1021/acs.jmedchem.8b00834
None Unchecked Ratio IC50/EC50 934.0 None 10.1021/acs.jmedchem.5b00085
None Unchecked Ratio Ki 330.0 None 10.1021/acs.jmedchem.1c00211
None Unchecked Relative IC50 1.0 None 10.1016/S0960-894X(01)80127-X
None Unchecked Relative IC50 1.0 None 10.1021/jm00017a020
None Unchecked Relative potency 32.5 None 10.1021/jm010126m
None Unchecked Relative potency 60.6 None 10.1021/jm010126m
None Unchecked Respiratory system resistance 13.0 None 10.1021/jm990615a
None Unchecked Respiratory system resistance 90.0 None 10.1021/jm990615a
None Unchecked Selectivity Index 18.4 None 10.1128/aac.00660-09

Metabolism Information