Stepharine
AlkaPlorer ID: AK011026
Synonym: None
IUPAC Name: (4S)-10,11-dimethoxyspiro[5-azatricyclo[6.3.1.04,12]dodeca-1(12),8,10-triene-2,4'-cyclohexa-2,5-diene]-1'-one
Structure
SMILES: COC1=CC2=C3C(=C1OC)C1(C=CC(=O)C=C1)C[C@@H]3NCC2
InChI: InChI=1S/C18H19NO3/c1-21-14-9-11-5-8-19-13-10-18(6-3-12(20)4-7-18)16(15(11)13)17(14)22-2/h3-4,6-7,9,13,19H,5,8,10H2,1-2H3/t13-/m0/s1
InChIKey: OGJKMZVUJJYWKO-ZDUSSCGKSA-N
Reference
Aporphine alkaloids from the roots of<i>Stephania viridiflavens</i>
PubChem CID: 830726
LOTUS: LTS0134128
SuperNatural Ⅲ: SN0264695-02
NPASS: NPC2770
data_source: manually
Source
Properties Information
Molecule Weight: 297.35400000000004
TPSA？: 47.56
MolLogP？: 2.2272
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Trypanosoma cruzi | Trypanosoma cruzi | Activity | 65.0 | % | 10.1021/np960223w |