Atherosperminine; 2-O-De-Me
AlkaPlorer ID: AK011931
Synonym: 1-[2-(Dimethylamino)ethyl]-4-methoxy-3-phenanthrenol, 1-(2-Dimethylaminoethyl)-3-hydroxy-4-methoxyphenanthrene, Argentinine
IUPAC Name: 1-[2-(dimethylamino)ethyl]-4-methoxyphenanthren-3-ol
Structure
SMILES: COC1=C(O)C=C(CCN(C)C)C2=CC=C3C=CC=CC3=C12
InChI: InChI=1S/C19H21NO2/c1-20(2)11-10-14-12-17(21)19(22-3)18-15-7-5-4-6-13(15)8-9-16(14)18/h4-9,12,21H,10-11H2,1-3H3
InChIKey: HCXNUWJYBNHDAE-UHFFFAOYSA-N
Reference
Chromone and Phenanthrene Alkaloids from Dennettia tripetala.
PubChem CID: 10085878
CAS: 16625-57-3
LOTUS: LTS0092147
SuperNatural Ⅲ: SN0122211
COCONUT: CNP0147432
data_source: manually
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Annona montana | Annona | Annonaceae | Magnoliales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Monodora angolensis | Monodora | Annonaceae | Magnoliales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| None | Enantia | Pieridae | Lepidoptera | Insecta | Arthropoda | Metazoa | Eukaryota |
| None | Enantia | Pieridae | Lepidoptera | Insecta | Arthropoda | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 295.382
TPSA？: 32.7
MolLogP？: 3.811300000000003
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Leishmania amazonensis | Leishmania amazonensis | Activity | nan | None | 10.1021/np50109a003 |
| Leishmania braziliensis | Leishmania braziliensis | Activity | nan | None | 10.1021/np50109a003 |
| Leishmania donovani | Leishmania donovani | Activity | nan | None | 10.1021/np50109a003 |
| Trypanosoma cruzi | Trypanosoma cruzi | Activity | 81.3 | % | 10.1021/np50109a003 |