Chonemorphine
AlkaPlorer ID: AK012319
Synonym: None
IUPAC Name: None
Structure
SMILES: C[C@@H]([C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@H]([NH3+])CC[C@]4(C)[C@H]3CC[C@]12C)[NH+](C)C
InChI: InChI=1S/C23H42N2/c1-15(25(4)5)19-8-9-20-18-7-6-16-14-17(24)10-12-22(16,2)21(18)11-13-23(19,20)3/h15-21H,6-14,24H2,1-5H3/p+2/t15-,16-,17-,18-,19+,20-,21-,22-,23+/m0/s1
InChIKey: MJGLREGOLPEPID-GHKGYAFRSA-P
Reference
Chonemorphine and Rapanone--Antiparasitic Agents from Plant Sources
LOTUS: LTS0167774
SuperNatural Ⅲ: SN0227196-02
NPASS: NPC53276
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Sarcococca hookeriana | Sarcococca | Buxaceae | Buxales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 348.61900000000014
TPSA？: 32.08
MolLogP？: 2.788800000000003
Number of H-Donors: 2
Number of H-Acceptors: 0
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | IZ | 16.5 | mm | 10.1021/np800305b |
| Bacillus subtilis | Bacillus subtilis | MIC | 90300.0 | nM | 10.1021/np800305b |
| Enterococcus faecalis | Enterococcus faecalis | IZ | 10.0 | mm | 10.1021/np800305b |
| Homo sapiens | Acetylcholinesterase | IC50 | 28000.0 | nM | 10.1021/np800305b |
| Homo sapiens | Butyrylcholinesterase | IC50 | 500.0 | nM | 10.1021/np800305b |
| Micrococcus luteus | Micrococcus luteus | IZ | 11.5 | mm | 10.1021/np800305b |
| Micrococcus luteus | Micrococcus luteus | MIC | 90300.0 | nM | 10.1021/np800305b |
| Pseudomonas | Pseudomonas | IZ | 14.0 | mm | 10.1021/np800305b |
| Pseudomonas | Pseudomonas | MIC | 180600.0 | nM | 10.1021/np800305b |