Vibrindole A
AlkaPlorer ID: AK012344
Synonym: None
IUPAC Name: 3-[1-(1H-indol-3-yl)ethyl]-1H-indole
Structure
SMILES: CC(C1=CNC2=CC=CC=C12)C1=CNC2=CC=CC=C12
InChI: InChI=1S/C18H16N2/c1-12(15-10-19-17-8-4-2-6-13(15)17)16-11-20-18-9-5-3-7-14(16)18/h2-12,19-20H,1H3
InChIKey: WOJBBIJJRKFKOJ-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Vibrio parahaemolyticus | Vibrio | Vibrionaceae | Vibrionales | Gammaproteobacteria | Pseudomonadota | None | Bacteria |
Properties Information
Molecule Weight: 260.34000000000003
TPSA？: 31.58
MolLogP？: 4.801000000000003
Number of H-Donors: 2
Number of H-Acceptors: 0
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | IZ | 7.0 | mm | 10.1021/np50113a022 |
| Homo sapiens | Free fatty acid receptor 1 | Activity | nan | None | 10.1021/acs.jmedchem.6b01593 |
| Homo sapiens | G-protein coupled receptor 120 | Activity | nan | None | 10.1021/acs.jmedchem.6b01593 |
| Homo sapiens | G-protein coupled receptor 120 | Inhibition | nan | % | 10.1021/acs.jmedchem.6b01593 |
| Homo sapiens | G-protein coupled receptor 84 | EC50 | 10000.0 | nM | 10.1021/acs.jmedchem.6b01593 |
| Homo sapiens | G-protein coupled receptor 84 | Emax | -5.0 | % | 10.1021/acs.jmedchem.6b01593 |
| Homo sapiens | G-protein coupled receptor 84 | Emax | 3.0 | % | 10.1021/acs.jmedchem.6b01593 |
| Homo sapiens | G-protein coupled receptor 84 | Inhibition | nan | % | 10.1021/acs.jmedchem.6b01593 |
| Staphylococcus | Staphylococcus | IZ | 11.0 | mm | 10.1021/np50113a022 |
| Staphylococcus aureus | Staphylococcus aureus | IZ | 11.0 | mm | 10.1021/np50113a022 |