(3R)-7-(4-hydroxy-5-methoxy-7-methylnaphthalen-1-yl)-8-methoxy-1,3-dimethyl-3,4-dihydroisoquinolin-6-ol
AlkaPlorer ID: AK012548
Synonym: None
IUPAC Name: (3R)-7-(4-hydroxy-5-methoxy-7-methylnaphthalen-1-yl)-8-methoxy-1,3-dimethyl-3,4-dihydroisoquinolin-6-ol
Structure
SMILES: COC1=C2C(C)=N[C@H](C)CC2=CC(O)=C1C1=CC=C(O)C2=C(OC)C=C(C)C=C12
InChI: InChI=1S/C24H25NO4/c1-12-8-17-16(6-7-18(26)22(17)20(9-12)28-4)23-19(27)11-15-10-13(2)25-14(3)21(15)24(23)29-5/h6-9,11,13,26-27H,10H2,1-5H3/t13-/m1/s1
InChIKey: YNZRHQDRHHJZQU-CYBMUJFWSA-N
Reference
Yaoundamines A and B, new antimalarial naphthylisoquinoline alkaloids from Ancistrocladus korupensis
PubChem CID: 392429
LOTUS: LTS0115703
SuperNatural Ⅲ: SN0455625-01
NPASS: NPC71819
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Ancistrocladus ealaensis | Ancistrocladus | Ancistrocladaceae | Caryophyllales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 391.46700000000016
TPSA？: 71.28
MolLogP？: 4.997220000000006
Number of H-Donors: 2
Number of H-Acceptors: 5
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | PANC-1 | Activity | nan | None | 10.1021/acs.jnatprod.9b00755 |
| Homo sapiens | PANC-1 | PC50 | 37.8 | uM | 10.1021/acs.jnatprod.9b00755 |