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L-homoserine

AlkaPlorer ID: AK012897

Synonym: '', 'L-Homoserine', 'Homoserine', '2-Amino-4-hydroxybutyric acid', 'L-HOMOSERINE', '(2S)-2-amino-4-hydroxybutanoic acid', '2-Amino-4-hydroxybutanoic acid', '672-15-1'

IUPAC Name: (2S)-2-amino-4-hydroxybutanoic acid

Structure

SMILES: N[C@@H](CCO)C(=O)O

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InChI: InChI=1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1

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InChIKey: UKAUYVFTDYCKQA-VKHMYHEASA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Polygonatum sibiricum Polygonatum Asparagaceae Asparagales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Eucalyptus globulus Eucalyptus Myrtaceae Myrtales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Canavalia gladiata Canavalia Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Astragalus sinicus Astragalus Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Pulicaria arabica Pulicaria Asteraceae Asterales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Pterocarpus indicus Pterocarpus Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Pisum sativum Pisum Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Homo sapiens Homo Hominidae Primates Mammalia Chordata Metazoa Eukaryota
Salvia trijuga Salvia Lamiaceae Lamiales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Glycine falcata Glycine Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Polygonatum cyrtonema Polygonatum Asparagaceae Asparagales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Saccharomyces cerevisiae Saccharomyces Saccharomycetaceae Saccharomycetales Saccharomycetes Ascomycota Fungi Eukaryota
Chlamydomonas reinhardtii Chlamydomonas Chlamydomonadaceae Chlamydomonadales Chlorophyceae Chlorophyta Viridiplantae Eukaryota
Achillea moschata Achillea Asteraceae Asterales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Escherichia coli Escherichia Enterobacteriaceae Enterobacterales Gammaproteobacteria Pseudomonadota None Bacteria
Deamia testudo Deamia Cactaceae Caryophyllales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Picradeniopsis pringlei Picradeniopsis Asteraceae Asterales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 119.11999999999998

TPSA？: 83.55

MolLogP？: -1.2192999999999998

Number of H-Donors: 3

Number of H-Acceptors: 3

RingCount: 0

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Rattus norvegicus Amino acid transporter Inhibition 25.0 % None
None Unchecked Activity nan None 10.1016/j.bmc.2008.04.015
None Unchecked krel nan None 10.1016/s0960-894x(98)00164-4

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT000054 *C(=O)CC(=O)/C(C)=C/C=C/C(C)=C/C(C)=C/C(C)=C\C.N[C@@H](CCO)C(=O)O>>C/C=C(C)\C=C(C)\C=C(C)\C=C\C=C(/C)C(=O)C1=CC(CCO)NC1=O RXN-16739
AKRT001469 C/C=C/C(=O)OCC[C@H](N)C(=O)O>>N[C@@H](CCO)C(=O)O enzymemap_30725
AKRT001473 C/C=C/C(=O)[CoA].N[C@@H](CCO)C(=O)O>>C/C=C/C(=O)OCC[C@H](N)C(=O)O enzymemap_30725
AKRT004181 CC(=O)OCC[C@H](N)C(=O)O>>CC(=O)[32S].N[C@@H](CCO)C(=O)O None
AKRT004435 CC(=O)[32S].N[C@@H](CCO)C(=O)O>>CC(=O)OCC[C@H](N)C(=O)O None
AKRT004695 CC(=O)[CoA].N[C@@H](CCO)C(=O)O>>CC(=O)OCC[C@H](N)C(=O)O R01776
AKRT005387 CC(C)C(=O)[CoA].N[C@@H](CCO)C(=O)O>>CC(C)C(=O)OCC[C@H](N)C(=O)O enzymemap_30723
AKRT006631 CC(O)CC(=O)[CoA].N[C@@H](CCO)C(=O)O>>CC(O)CC(=O)N[C@@H](CCO)C(=O)O enzymemap_30722
AKRT007193 CCC(=O)[CoA].N[C@@H](CCO)C(=O)O>>CCC(=O)OCC[C@H](N)C(=O)O enzymemap_30729
AKRT007444 CCCC(=O)[CoA].N[C@@H](CCO)C(=O)O>>CCCC(=O)OCC[C@H](N)C(=O)O enzymemap_30728
AKRT014469 C[S+](C)CC[C@H](N)C(=O)O>>N[C@@H](CCO)C(=O)O RXN-19156
AKRT014536 C[S@@+](CC[C@H](N)C(=O)O)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O>>N[C@@H](CCO)C(=O)O ADENOSYLMETHIONINE-HYDROLASE-RXN
AKRT016989 NC(=O)Cc1cc(=O)oc2cc(NC(=O)[C@@H](N)CCO)ccc12>>N[C@@H](CCO)C(=O)O enzymemap_65337
AKRT018554 NOCC[C@H](N)C(=O)O>>N[C@@H](CCO)C(=O)O RXN-35
AKRT018768 N[C@@H](CC=O)C(=O)O>>N[C@@H](CCO)C(=O)O HOMOSERDEHYDROG-RXN
AKRT019342 N[C@@H](CCO)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O>>N[C@@H](CCC(=O)N[C@@H](CCO)C(=O)O)C(=O)O enzymemap_90498
AKRT019343 N[C@@H](CCO)C(=O)O.N[C@@H](CS)C(=O)O>>N[C@@H](CCSC[C@H](N)C(=O)O)C(=O)O CYSTATHIONASE-RXN
AKRT019344 N[C@@H](CCO)C(=O)O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O>>N[C@@H](CCOP(=O)(O)O)C(=O)O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O None
AKRT019345 N[C@@H](CCO)C(=O)O.O=C(O)CCC(=O)C(=O)O>>N[C@@H](CCC(=O)O)C(=O)O.O=C(O)C(=O)CCO None
AKRT019346 N[C@@H](CCO)C(=O)O.O=C(O)CCC(=O)[32S]>>N[C@@H](CCOC(=O)CCC(=O)O)C(=O)O None
AKRT019347 N[C@@H](CCO)C(=O)O.O=C(O)CCC(=O)[CoA]>>N[C@@H](CCOC(=O)CCC(=O)O)C(=O)O HOMSUCTRAN-RXN
AKRT019348 N[C@@H](CCO)C(=O)O.O=CC(=O)O>>O=C(O)C(=O)CCO enzymemap_41631
AKRT019349 N[C@@H](CCO)C(=O)O>>C/C=C(\N)C(=O)O RXN-14049
AKRT019350 N[C@@H](CCO)C(=O)O>>CCC(=O)C(=O)O HOMOSERDEAM-RXN
AKRT019351 N[C@@H](CCO)C(=O)O>>NCC(=O)O enzymemap_41631
AKRT019352 N[C@@H](CCO)C(=O)O>>NOCC[C@H](N)C(=O)O RXN-25
AKRT019353 N[C@@H](CCO)C(=O)O>>N[C@@H](CC=O)C(=O)O enzymemap_4024
AKRT019354 N[C@@H](CCO)C(=O)O>>N[C@@H](CCOP(=O)(O)O)C(=O)O HOMOSERKIN-RXN
AKRT019355 N[C@@H](CCO)C(=O)O>>N[C@@H](CCS)C(=O)O enzymemap_40672
AKRT019356 N[C@@H](CCO)C(=O)O>>N[C@H](CCO)C(=O)O RXN0-7285
AKRT019357 N[C@@H](CCO)C(=O)O>>O=C(O)C(=O)CCO enzymemap_21475
AKRT019363 N[C@@H](CCOC(=O)CCC(=O)O)C(=O)O>>N[C@@H](CCO)C(=O)O R01777
AKRT019364 N[C@@H](CCOC(=O)CCC(=O)O)C(=O)O>>N[C@@H](CCO)C(=O)O.O=C(O)CCC(=O)[32S] None
AKRT019368 N[C@@H](CCOC(=O)CCCC(=O)O)C(=O)O>>N[C@@H](CCO)C(=O)O enzymemap_30959
AKRT019376 N[C@@H](CCOP(=O)(O)O)C(=O)O>>N[C@@H](CCO)C(=O)O enzymemap_55887
AKRT019403 N[C@@H](CCSC[C@H](N)C(=O)O)C(=O)O>>N[C@@H](CCO)C(=O)O CYSTATHIONASE-RXN
AKRT020264 N[C@H](CCO)C(=O)O>>N[C@@H](CCO)C(=O)O RXN0-7285
AKRT020414 N[C@H]1CCOC1=O>>N[C@@H](CCO)C(=O)O enzymemap_54242
AKRT022574 O=C(O)C(=O)CCO>>N[C@@H](CCO)C(=O)O enzymemap_42470
AKRT022712 O=C(O)CC(=O)[CoA].N[C@@H](CCO)C(=O)O>>N[C@@H](CCOC(=O)CC(=O)O)C(=O)O enzymemap_30724
AKRT022753 O=C(O)CCC(=O)[CoA].N[C@@H](CCO)C(=O)O>>N[C@@H](CCOC(=O)CCC(=O)O)C(=O)O enzymemap_30721
AKRT022778 O=C(O)CCCC(=O)[CoA].N[C@@H](CCO)C(=O)O>>N[C@@H](CCOC(=O)CCCC(=O)O)C(=O)O enzymemap_30726