Annomontine; N9-Hydroxy
AlkaPlorer ID: AK013013
Synonym: N9-Hydroxyannomontine
IUPAC Name: 4-(9-hydroxypyrido[3,4-b]indol-1-yl)pyrimidin-2-amine
Structure
SMILES: N=C1N=C(C2=NC=CC3=C2N(O)C2=C3C=CC=C2)C=CN1
InChI: InChI=1S/C15H11N5O/c16-15-18-8-6-11(19-15)13-14-10(5-7-17-13)9-3-1-2-4-12(9)20(14)21/h1-8,21H,(H2,16,18,19)
InChIKey: CUDZAZQWOSIPTN-UHFFFAOYSA-N
Reference
PubChem CID: 11687726
CAS: 878049-56-0
LOTUS: LTS0219883
SuperNatural Ⅲ: SN0055689
NPASS: NPC225018
COCONUT: CNP0181707
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Annona foetida | Annona | Annonaceae | Magnoliales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 277.287
TPSA？: 90.58
MolLogP？: 2.29637
Number of H-Donors: 3
Number of H-Acceptors: 5
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Leishmania braziliensis | Leishmania braziliensis | IC50 | 252700.0 | nM | 10.1021/np050422s |
| Leishmania guyanensis | Leishmania guyanensis | IC50 | 437500.0 | nM | 10.1021/np050422s |