4-methylene-L-glutamic acid
AlkaPlorer ID: AK013227
Synonym: None
IUPAC Name: (2S)-2-amino-4-methylidenepentanedioic acid
Structure
SMILES: C=C(C[C@H](N)C(=O)O)C(=O)O
InChI: InChI=1S/C6H9NO4/c1-3(5(8)9)2-4(7)6(10)11/h4H,1-2,7H2,(H,8,9)(H,10,11)/t4-/m0/s1
InChIKey: RCCMXKJGURLWPB-BYPYZUCNSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Lilium candidum | Lilium | Liliaceae | Liliales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 159.141
TPSA？: 100.62000000000002
MolLogP？: -0.5708000000000002
Number of H-Donors: 3
Number of H-Acceptors: 3
RingCount: 0
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Glutamate receptor ionotropic kainate 1 | Ki | 270.0 | nM | 10.1016/s0960-894x(00)00346-2 |
| Homo sapiens | Glutamate receptor ionotropic kainate 2 | Ki | 450.0 | nM | 10.1016/s0960-894x(00)00346-2 |
| Homo sapiens | Metabotropic glutamate receptor 1 | Ki | 150.0 | nM | 10.1021/jm000007r |
| Homo sapiens | Metabotropic glutamate receptor 2 | Ki | 230.0 | nM | 10.1021/jm000007r |
| Homo sapiens | Metabotropic glutamate receptor 4 | Ki | 1000000.0 | nM | 10.1021/jm000007r |
| Rattus norvegicus | Metabotropic glutamate receptor 1 | EC50 ratio | 0.7 | None | 10.1021/jm980571q |
| Rattus norvegicus | Metabotropic glutamate receptor 2 | EC50 ratio | nan | None | 10.1021/jm980571q |
| Rattus norvegicus | Vesicular glutamate transporter 3 | Ki | 3000.0 | nM | 10.1021/jm010261z |
| None | Unchecked | Ratio | 1.67 | None | 10.1016/s0960-894x(00)00346-2 |