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erythro-4-hydroxy-L-glutamate(1-)

AlkaPlorer ID: AK013469

Synonym: 'erythro-4-hydroxy-L-glutamic acid', '(2S,4R)-2-amino-4-hydroxypentanedioic acid', 'erythro-4-hydroxy-L-glutamate', 'L-erythro-4-hydroxyglutamic acid', '(2S,4R)-2-ammonio-4-hydroxypentanedioate'

IUPAC Name: (2S,4S)-2-amino-4-hydroxypentanedioic acid

Structure

SMILES: N[C@@H](C[C@H](O)C(=O)O)C(=O)O

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InChI: InChI=1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/t2-,3-/m0/s1

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InChIKey: HBDWQSHEVMSFGY-HRFVKAFMSA-N

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Reference

PubChem CID: 192790

CAS: 3913-68-6

SuperNatural Ⅲ: SN0120802-01

NPASS: NPC88898

Source

Species Genus Family Order Class Phylum Kingdom Domain
Hemerocallis fulva Hemerocallis Asphodelaceae Asparagales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 163.129

TPSA？: 120.85

MolLogP？: -1.7660999999999991

Number of H-Donors: 4

Number of H-Acceptors: 4

RingCount: 0

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Homo sapiens Excitatory amino acid transporter 1 Km 140000.0 nM 10.1021/jm050597z
Homo sapiens Excitatory amino acid transporter 1 pKm 4.06 None 10.1021/jm050597z
Homo sapiens Excitatory amino acid transporter 2 Km 67000.0 nM 10.1021/jm050597z
Homo sapiens Excitatory amino acid transporter 2 pKm 4.21 None 10.1021/jm050597z
Homo sapiens Excitatory amino acid transporter 3 Km 81000.0 nM 10.1021/jm050597z
Homo sapiens Excitatory amino acid transporter 3 pKm 4.16 None 10.1021/jm050597z
Rattus norvegicus Metabotropic glutamate receptor 1 EC50 11000.0 nM 10.1016/s0960-894x(01)00158-5
Rattus norvegicus Metabotropic glutamate receptor 1 Rmax 95.0 mM 10.1016/s0960-894x(01)00158-5
Rattus norvegicus Metabotropic glutamate receptor 2 EC50 137000.0 nM 10.1016/s0960-894x(01)00158-5
Rattus norvegicus Metabotropic glutamate receptor 2 Rmax 60.0 mM 10.1016/s0960-894x(01)00158-5
Rattus norvegicus Metabotropic glutamate receptor 8 EC50 53000.0 nM 10.1016/s0960-894x(01)00158-5
Rattus norvegicus Metabotropic glutamate receptor 8 Rmax 94.0 mM 10.1016/s0960-894x(01)00158-5

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT010200 CC[C@H](N)C(=O)O.N[C@@H](C[C@H](O)C(=O)O)C(=O)O>>CC[C@H](NC(=O)[C@@H](N)C[C@H](O)C(=O)O)C(=O)O enzymemap_90537