Limazepine D
AlkaPlorer ID: AK013560
Synonym: None
IUPAC Name: 8-ethyl-4-hydroxy-3-methoxypyrrolo[2,1-c][1,4]benzodiazepin-11-one
Structure
SMILES: CCC1=CN2C(=O)C3=CC=C(OC)C(O)=C3N=CC2=C1
InChI: InChI=1S/C15H14N2O3/c1-3-9-6-10-7-16-13-11(15(19)17(10)8-9)4-5-12(20-2)14(13)18/h4-8,18H,3H2,1-2H3
InChIKey: SKMAAAVNEKWJHB-UHFFFAOYSA-N
Reference
Limazepines A−F, Pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian <i>Micrococcus</i> sp.
PubChem CID: 42639335
CAS: 1143525-64-7
LOTUS: LTS0037654
SuperNatural Ⅲ: SN0348033
COCONUT: CNP0159386
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | None | Micrococcaceae | Micrococcales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 270.288
TPSA？: 63.83
MolLogP？: 2.1243
Number of H-Donors: 1
Number of H-Acceptors: 5
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | Activity | nan | None | 10.1021/np800827w |
| Candida albicans | Candida albicans | Activity | nan | None | 10.1021/np800827w |
| Escherichia coli | Escherichia coli | IZ | nan | None | 10.1021/np800827w |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | IZ | 9.0 | mm | 10.1021/np800827w |
| Rhizomucor miehei | Rhizomucor miehei | Activity | nan | None | 10.1021/np800827w |
| Staphylococcus aureus | Staphylococcus aureus | IZ | 7.0 | mm | 10.1021/np800827w |