Molecule

Forticine

AlkaPlorer ID: AK013883

Synonym: '', 'Persicanidine A', 'Persicanidine B', 'Ebeiedine', 'Tortifoline', 'Harepermine', 'Petilidine', '(-)-Tortifoline', 'Eduardinine', 'Hupehenine', 'Edpetilidine', 'Songbeinine', 'Ebeinine', 'Delavine'

IUPAC Name: (1R,2S,6S,9R,10S,11R,14S,15S,17R,18S,20S,23R,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-17,20-diol

Structure

SMILES: C[C@H]1CC[C@@H]2[C@@H](C)[C@@H]3CC[C@@H]4[C@@H](C[C@H]5[C@H]4C[C@@H](O)[C@H]4C[C@@H](O)CC[C@@]45C)[C@@H]3CN2C1

InChI: InChI=1S/C27H45NO2/c1-15-4-7-25-16(2)18-5-6-19-20(22(18)14-28(25)13-15)11-23-21(19)12-26(30)24-10-17(29)8-9-27(23,24)3/h15-26,29-30H,4-14H2,1-3H3/t15-,16-,17-,18-,19+,20+,21-,22+,23-,24+,25+,26+,27+/m0/s1

InChIKey: NEMWYOKGHGSVSC-SECATLSXSA-N

Reference

Tortifoline, a novel (20S, 22R)-5.ALPHA.-cevanine alkaloid from Fritillaria tortifolia.

PubChem CID: 21636310

LOTUS: LTS0197280

SuperNatural Ⅲ: SN0243282-35

NPASS: NPC115554

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Boletinus cavipes	Boletinus	Gyrodontaceae	Boletales	Agaricomycetes	Basidiomycota	Fungi	Eukaryota
Cenchrus setaceus	Cenchrus	Poaceae	Poales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Trichopezizella barbata	Trichopezizella	Solenopeziaceae	Helotiales	Leotiomycetes	Ascomycota	Fungi	Eukaryota
Choristoneura rosaceana	Choristoneura	Tortricidae	Lepidoptera	Insecta	Arthropoda	Metazoa	Eukaryota
Salvia macrosiphon	Salvia	Lamiaceae	Lamiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Caragana stenophylla	Caragana	Fabaceae	Fabales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Conoideocrella tenuis	Conoideocrella	Clavicipitaceae	Hypocreales	Sordariomycetes	Ascomycota	Fungi	Eukaryota
Acacia trineura	Acacia	Fabaceae	Fabales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Diospyros lotus	Diospyros	Ebenaceae	Ericales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota

Properties Information

Molecule Weight: 415.66200000000026

TPSA？: 43.7

MolLogP？: 4.563200000000005

Number of H-Donors: 2

Number of H-Acceptors: 3

RingCount: 6

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Electrophorus electricus	Acetylcholinesterase	IC50	5850.0	nM	10.1016/j.ejmech.2017.06.007
Electrophorus electricus	Acetylcholinesterase	Inhibition	nan	%	10.1016/j.ejmech.2017.06.007
Equus caballus	Cholinesterase	IC50	2080.0	nM	10.1016/j.ejmech.2017.06.007
None	Unchecked	Ratio IC50	0.36	None	10.1016/j.ejmech.2017.06.007