6-methoxy-1-methyl-2-phenylquinolin-4-one
AlkaPlorer ID: AK014032
Synonym: '6-methoxy-1-methyl-2-phenyl-4(1H)-quinolinone', 'MLS000549197', 'SMR000113847'
IUPAC Name: 6-methoxy-1-methyl-2-phenylquinolin-4-one
Structure
SMILES: COC1=CC=C2C(=C1)C(=O)C=C(C1=CC=CC=C1)N2C
InChI: InChI=1S/C17H15NO2/c1-18-15-9-8-13(20-2)10-14(15)17(19)11-16(18)12-6-4-3-5-7-12/h3-11H,1-2H3
InChIKey: GFUAPSNFZWUMBP-UHFFFAOYSA-N
Reference
Citrus bitter principles. IX. Extractives of Casimiroa edulis. Structure of zapoterin
PubChem CID: 622180
LOTUS: LTS0187369
SuperNatural Ⅲ: SN0104563
COCONUT: CNP0187679
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Orixa japonica | Orixa | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 265.312
TPSA？: 31.23
MolLogP？: 3.214100000000001
Number of H-Donors: 0
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Escherichia coli K-12 | Beta-lactamase AmpC | Potency | 25118.9 | nM | None |
| Homo sapiens | 15-hydroxyprostaglandin dehydrogenase [NAD+] | Potency | 28183.8 | nM | None |
| Homo sapiens | Aldehyde dehydrogenase 1A1 | Potency | 39810.7 | nM | None |
| Homo sapiens | ATPase family AAA domain-containing protein 5 | Potency | 23109.3 | nM | None |
| Homo sapiens | Breast cancer type 1 susceptibility protein | Potency | 12589.3 | nM | None |
| Homo sapiens | Cellular tumor antigen p53 | Potency | 50118.7 | nM | None |
| Homo sapiens | Chromobox protein homolog 1 | Potency | 89125.1 | nM | None |
| Homo sapiens | DNA polymerase iota | Potency | 70794.6 | nM | None |
| Homo sapiens | HEK293 | Potency | 4466.8 | nM | None |
| Homo sapiens | Lysine-specific demethylase 4D-like | Potency | 28183.8 | nM | None |
| Homo sapiens | microRNA 21 | Potency | 10399.2 | nM | None |
| Homo sapiens | Muscleblind-like protein 1 | Potency | 5011.9 | nM | None |
| Homo sapiens | Neuropeptide S receptor | Potency | 4.0 | nM | None |
| Homo sapiens | Nuclear factor erythroid 2-related factor 2 | Potency | 11220.2 | nM | None |
| Homo sapiens | Survival motor neuron protein | Potency | 35481.3 | nM | None |
| Mus musculus | Nuclear receptor ROR-gamma | Potency | 12589.3 | nM | None |
| Photinus pyralis | Luciferin 4-monooxygenase | Potency | 23934.1 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 9285.0 | nM | None |