Kosinostatin
AlkaPlorer ID: AK015173
Synonym: None
IUPAC Name: (1S,16R,17R,19R)-16-[(2S,4R,5S,6S)-5-acetyl-4,5-dihydroxy-6-methyloxan-2-yl]oxy-3,10-dihydroxy-17-methylspiro[18-oxapentacyclo[15.2.1.02,15.04,13.06,11]icosa-2,4(13),6(11),7,9,14-hexaene-19,5'-3,6-dihydro-2H-pyrrolo[2,3-b]pyrrole]-5,12-dione
Structure
SMILES: CC(=O)[C@]1(O)[C@H](O)C[C@H](O[C@@H]2C3=CC4=C(C(=O)C5=CC=CC(O)=C5C4=O)C(O)=C3[C@@H]3C[C@@]2(C)O[C@]32C=C3CCN=C3N2)O[C@H]1C
InChI: InChI=1S/C33H32N2O10/c1-13(36)33(42)14(2)43-22(10-21(33)38)44-29-18-9-17-25(26(39)16-5-4-6-20(37)24(16)27(17)40)28(41)23(18)19-12-31(29,3)45-32(19)11-15-7-8-34-30(15)35-32/h4-6,9,11,14,19,21-22,29,37-38,41-42H,7-8,10,12H2,1-3H3,(H,34,35)/t14-,19-,21+,22-,29+,31+,32+,33+/m0/s1
InChIKey: IWQFYWITNQDEGF-LXJOWWJISA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Micromonospora sp. | Micromonospora | Micromonosporaceae | Micromonosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 616.623
TPSA？: 184.21
MolLogP？: 2.0511
Number of H-Donors: 5
Number of H-Acceptors: 12
RingCount: 8
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|