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L-2-amino-4-pentynoic acid

AlkaPlorer ID: AK015800

Synonym: None

IUPAC Name: (2S)-2-aminopent-4-ynoic acid

Structure

SMILES: C#CC[C@H](N)C(=O)O

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InChI: InChI=1S/C5H7NO2/c1-2-3-4(6)5(7)8/h1,4H,3,6H2,(H,7,8)/t4-/m0/s1

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InChIKey: DGYHPLMPMRKMPD-BYPYZUCNSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Streptomyces sp. Streptomyces Streptomycetaceae Kitasatosporales Actinomycetes Actinomycetota None Bacteria

Properties Information

Molecule Weight: 113.116

TPSA？: 63.32000000000001

MolLogP？: -0.5784000000000002

Number of H-Donors: 2

Number of H-Acceptors: 2

RingCount: 0

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Enterobacter cloacae Enterobacter cloacae MIC 100.0 ug.mL-1 10.1021/jm00366a015
Enterococcus faecalis Enterococcus faecalis MIC 100.0 ug.mL-1 10.1021/jm00366a015
Escherichia coli Escherichia coli MIC 100.0 ug.mL-1 10.1021/jm00366a015
Haemophilus influenzae Haemophilus influenzae MIC 100.0 ug.mL-1 10.1021/jm00366a015
Homo sapiens Cystathionine gamma-lyase IC50 40000.0 nM 10.1021/acsmedchemlett.7b00313
Klebsiella aerogenes Klebsiella aerogenes MIC 100.0 ug.mL-1 10.1021/jm00366a015
Klebsiella pneumoniae Klebsiella pneumoniae MIC 100.0 ug.mL-1 10.1021/jm00366a015
Morganella morganii Morganella morganii MIC 100.0 ug.mL-1 10.1021/jm00366a015
Proteus mirabilis Proteus mirabilis MIC 100.0 ug.mL-1 10.1021/jm00366a015
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 100.0 ug.mL-1 10.1021/jm00366a015
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 100.0 ug.mL-1 10.1021/jm00366a015
Serratia marcescens Serratia marcescens MIC 100.0 ug.mL-1 10.1021/jm00366a015
Shigella flexneri Shigella flexneri MIC 100.0 ug.mL-1 10.1021/jm00366a015
Staphylococcus aureus Staphylococcus aureus MIC 100.0 ug.mL-1 10.1021/jm00366a015
Staphylococcus epidermidis Staphylococcus epidermidis MIC 100.0 ug.mL-1 10.1021/jm00366a015
Streptococcus agalactiae Streptococcus agalactiae MIC 100.0 ug.mL-1 10.1021/jm00366a015
Streptococcus pyogenes Streptococcus pyogenes MIC 100.0 ug.mL-1 10.1021/jm00366a015

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT001114 C#C/C=C/C(=O)O>>C#CC[C@H](N)C(=O)O enzymemap_85664
AKRT001119 C#CC[C@H](N)C(=O)Nc1ccc2c(CC(N)=O)cc(=O)oc2c1>>C#CC[C@H](N)C(=O)O enzymemap_65344
AKRT001120 C#CC[C@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O>>C#CC[C@H](NC(=O)CC[C@H](N)C(=O)O)C(=O)O R12410
AKRT001121 C#CC[C@H](N)C(=O)O>>C#C/C=C/C(=O)O enzymemap_85664
AKRT001122 C#CC[C@H](N)C(=O)O>>C#CCC(=O)C(=O)O enzymemap_22156
AKRT001633 C=C(Cl)C[C@H](N)C(=O)O>>C#CC[C@H](N)C(=O)O R12409