1,2,3-Trihydroxydibenz[cd,f]indol-4(5H)-one; Tri-Me ether
AlkaPlorer ID: AK016272
Synonym: 1,2,3-Trimethoxydibenz[cd,f]indol-4(5H)-one, Piperolactam C
IUPAC Name: 13,14,15-trimethoxy-10-azatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),2,4,6,8,12,14-heptaen-11-one
Structure
SMILES: COC1=C(OC)C(OC)=C2C3=C1C(O)=NC3=CC1=CC=CC=C12
InChI: InChI=1S/C18H15NO4/c1-21-15-12-10-7-5-4-6-9(10)8-11-13(12)14(18(20)19-11)16(22-2)17(15)23-3/h4-8H,1-3H3,(H,19,20)
InChIKey: GYYIMUXZCUHECT-UHFFFAOYSA-N
Reference
Antifungal Amides from <i>Piper scutifolium</i> and <i>Piper hoffmanseggianum</i>
PubChem CID: 10881419
CAS: 116064-76-7
LOTUS: LTS0090023
SuperNatural Ⅲ: SN0119089
NPASS: NPC276060
COCONUT: CNP0151368
data_source: manually
Source
Properties Information
Molecule Weight: 309.321
TPSA？: 60.28
MolLogP？: 3.9685000000000015
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Cladosporium cladosporioides | Cladosporium cladosporioides | MIC | 5.0 | ug | 10.1021/np070347g |
| Cladosporium sphaerospermum | Cladosporium sphaerospermum | MIC | 50.0 | ug | 10.1021/np070347g |
| None | Platelet | Inhibition | 0.0 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 6.1 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 7.8 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 82.0 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 83.7 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 89.4 | % | 10.1021/np000063v |