Radicamine A
AlkaPlorer ID: AK016732
Synonym: None
IUPAC Name: (2R,3R,4R,5R)-2-(3-hydroxy-4-methoxyphenyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol
Structure
SMILES: COC1=CC=C([C@H]2N[C@H](CO)[C@@H](O)[C@@H]2O)C=C1O
InChI: InChI=1S/C12H17NO5/c1-18-9-3-2-6(4-8(9)15)10-12(17)11(16)7(5-14)13-10/h2-4,7,10-17H,5H2,1H3/t7-,10-,11-,12-/m1/s1
InChIKey: NEAQPVOYHYPSER-FAQVLOEFSA-N
Reference
Polyhydroxylated Alkaloids with Lipophilic Moieties as Glycosidase Inhibitors from Higher Plants
PubChem CID: 44569922
LOTUS: LTS0224205
NPASS: NPC37205
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Lobelia chinensis | Lobelia | Campanulaceae | Asterales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 255.27
TPSA？: 102.18
MolLogP？: -0.8722000000000001
Number of H-Donors: 5
Number of H-Acceptors: 6
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| None | Unchecked | IC50 | 4200.0 | nM | 10.1016/j.bmc.2008.10.063 |
| None | Unchecked | IC50 | 12000.0 | nM | 10.1016/j.bmc.2008.10.063 |
| None | Unchecked | IC50 | 66000.0 | nM | 10.1016/j.bmc.2008.10.063 |
| None | Unchecked | IC50 | 200000.0 | nM | 10.1016/j.bmc.2008.10.063 |