Oxazinomycin
AlkaPlorer ID: AK017905
Synonym: 'Oxazinomycin', 'Minimycin'
IUPAC Name: 5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-oxazine-2,4-dione
Structure
SMILES: O=C1N=C(O)C([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)=CO1
InChI: InChI=1S/C9H11NO7/c11-1-4-5(12)6(13)7(17-4)3-2-16-9(15)10-8(3)14/h2,4-7,11-13H,1H2,(H,10,14,15)/t4-,5-,6-,7+/m1/s1
InChIKey: REFHNSOTFKKRAI-GBNDHIKLSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces tanashiensis | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 245.187
TPSA？: 133.25
MolLogP？: -2.1056
Number of H-Donors: 4
Number of H-Acceptors: 8
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | HeLa | IC50 | 500.0 | nM | 10.1021/jm00142a010 |
| Mus musculus | L1210 | IC50 | 300.0 | nM | 10.1021/jm00142a010 |
| Mus musculus | L1210 | Inhibition | 5.0 | % | 10.1021/jm00142a010 |