7-hydroxy-8-methoxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid
AlkaPlorer ID: AK018219
Synonym: None
IUPAC Name: 7-hydroxy-8-methoxy-3-methyl-10-oxochromeno[3,2-c]pyridine-9-carboxylic acid
Structure
SMILES: COC1=C(O)C=C2OC3=CC(C)=NC=C3C(=O)C2=C1C(=O)O
InChI: InChI=1S/C15H11NO6/c1-6-3-9-7(5-16-6)13(18)11-10(22-9)4-8(17)14(21-2)12(11)15(19)20/h3-5,17H,1-2H3,(H,19,20)
InChIKey: YKFKVOZQQDHYCE-UHFFFAOYSA-N
Reference
Polyketides with New Delhi Metallo-β-lactamase 1 Inhibitory Activity from <i>Penicillium</i> sp.
PubChem CID: 73349168
LOTUS: LTS0195094
COCONUT: CNP0267094
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | None | Trichocomaceae | Eurotiales | Eurotiomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 301.254
TPSA？: 109.86
MolLogP？: 2.0620199999999995
Number of H-Donors: 2
Number of H-Acceptors: 6
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Coxsackievirus B3 | Coxsackievirus B3 | Activity | nan | None | 10.1021/np4000944 |
| Homo sapiens | A549 | Activity | nan | None | 10.1021/np4000944 |
| Homo sapiens | Bel-7402 | Activity | nan | None | 10.1021/np4000944 |
| Homo sapiens | BGC-823 | Activity | nan | None | 10.1021/np4000944 |
| Homo sapiens | HCT-8 | Activity | nan | None | 10.1021/np4000944 |
| Homo sapiens | KETR3 | Activity | nan | None | 10.1021/np4000944 |
| Homo sapiens | MCF7 | Activity | nan | None | 10.1021/np4000944 |
| Influenza A virus | Influenza A virus | Activity | nan | None | 10.1021/np4000944 |
| Klebsiella pneumoniae | Klebsiella pneumoniae | Activity | nan | None | 10.1021/np4000944 |
| None | Unchecked | IC50 | 87900.0 | nM | 10.1021/np4000944 |