Molecule

2-amino-9-[(2-hydroxyethoxy)methyl]-9H-purin-6-ol

AlkaPlorer ID: AK019350

Synonym: None

IUPAC Name: 2-amino-9-(2-hydroxyethoxymethyl)-1H-purin-6-one

Structure

SMILES: NC1=NC(O)=C2N=CN(COCCO)C2=N1

InChI: InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)

InChIKey: MKUXAQIIEYXACX-UHFFFAOYSA-N

Reference

PubChem CID: 135398513

CAS: 141294-79-3

NPASS: NPC35410

COCONUT: CNP0335007

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Jatropha dioica	Jatropha	Euphorbiaceae	Malpighiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Houttuynia cordata	Houttuynia	Saururaceae	Piperales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Lyonia ovalifolia	Lyonia	Ericaceae	Ericales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Rhododendron latoucheae	Rhododendron	Ericaceae	Ericales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota

Properties Information

Molecule Weight: 225.208

TPSA？: 119.31000000000002

MolLogP？: -0.9195

Number of H-Donors: 3

Number of H-Acceptors: 8

RingCount: 2

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Acinetobacter baumannii	Acinetobacter baumannii	Inhibition	6.13	%	10.6019/CHEMBL4513141
Acinetobacter baumannii	Acinetobacter baumannii	MIC	20000.0	nM	10.6019/CHEMBL4513161
African swine fever virus	African swine fever virus	ED50	40.0	ug ml-1	10.1021/jm00172a026
Bacillus subtilis	4'-phosphopantetheinyl transferase ffp	Potency	70794.6	nM	None
Bos taurus	Progesterone receptor	IC50	nan	None	None
Bos taurus	Progesterone receptor	Ki	nan	None	None
Bovine alphaherpesvirus 1	Bovine alphaherpesvirus 1	MIC	7.0	ug.mL-1	10.1021/jm00402a017
Bovine viral diarrhea virus 1	Bovine viral diarrhea virus 1	EC50	100000.0	nM	10.1016/j.bmc.2009.05.020
Bovine viral diarrhea virus 1	Bovine viral diarrhea virus 1	EC50	100000.0	nM	10.1016/j.bmc.2010.02.037
Bovine viral diarrhea virus 1	Bovine viral diarrhea virus 1	EC50	100000.0	nM	10.1016/j.bmc.2014.06.043
Bovine viral diarrhea virus 1	Bovine viral diarrhea virus 1	EC50	100000.0	nM	10.1016/j.bmc.2015.09.035
Candida albicans	Candida albicans	Inhibition	4.6	%	10.6019/CHEMBL4513141
Candida albicans	Candida albicans	MIC	20000.0	nM	10.6019/CHEMBL4513161
Canis lupus familiaris	MDCK	CC50	nan	None	10.1021/np050498o
Canis lupus familiaris	MDCK	logPapp	-5.87	None	10.1021/jm901846t
Canis lupus familiaris	MDCK	MNCC	nan	None	10.1021/np050498o
Cavia porcellus	Cavia porcellus	Duration time	4.2	None	10.1021/jm00127a010
Cavia porcellus	Cavia porcellus	Duration time	5.4	None	10.1021/jm00127a010
Cavia porcellus	Cavia porcellus	Log geometric mean	2.13	pfu mg-1	10.1021/jm00371a024
Cavia porcellus	Cavia porcellus	Log geometric mean	3.31	pfu mg-1	10.1021/jm00371a024
Cavia porcellus	Cavia porcellus	Log geometric mean	4.09	pfu mg-1	10.1021/jm00371a024
Cavia porcellus	Cavia porcellus	Log geometric mean	4.3	pfu mg-1	10.1021/jm00371a024
Cavia porcellus	Cavia porcellus	Mean vesicle score	0.58	None	10.1021/jm00371a024
Cavia porcellus	Cavia porcellus	Mean vesicle score	0.83	None	10.1021/jm00371a024
Cavia porcellus	Cavia porcellus	Mean vesicle score	1.0	None	10.1021/jm00371a024
Cavia porcellus	Cavia porcellus	Mean vesicle score	1.16	None	10.1021/jm00371a024
Cavia porcellus	Cavia porcellus	Severity mean	2.4	None	10.1021/jm00127a010
Cavia porcellus	Cavia porcellus	Total score	14.0	None	10.1021/jm00127a010
Cavia porcellus	Cavia porcellus	Total score	60.4	None	10.1021/jm00127a010
Cavia porcellus	Leukotriene C4 synthase	IC50	nan	None	None
Cavia porcellus	Leukotriene C4 synthase	Ki	nan	None	None
Cavia porcellus	Serotonin 4 (5-HT4) receptor	IC50	nan	None	None
Cavia porcellus	Serotonin 4 (5-HT4) receptor	Ki	nan	None	None
Cercopithecine alphaherpesvirus 9	Cercopithecine alphaherpesvirus 9	ID50	100.0	uM	10.1021/jm00061a013
Chikungunya virus	Chikungunya virus	EC	nan	None	10.1021/acs.jnatprod.2c00464
Chikungunya virus	Chikungunya virus	FC	nan	None	10.1021/acs.jnatprod.2c00464
Chlorocebus sabaeus	Vero	CC100	600.0	ug ml-1	10.1016/j.ejmech.2009.10.010
Chlorocebus sabaeus	Vero	CC100	600.0	ug ml-1	10.1021/np010206t
Chlorocebus sabaeus	Vero	CC100	600.0	ug ml-1	10.1021/np010207l
Chlorocebus sabaeus	Vero	CC50	10.0	ug.mL-1	10.1016/S0960-894X(01)80693-4
Chlorocebus sabaeus	Vero	CC50	10.0	ug.mL-1	10.1021/np020234r
Chlorocebus sabaeus	Vero	CC50	100.0	ug.mL-1	10.1016/s0960-894x(01)00589-3
Chlorocebus sabaeus	Vero	CC50	130.0	ug.mL-1	10.1016/j.bmcl.2012.07.098
Chlorocebus sabaeus	Vero	CC50	500.0	ug.mL-1	10.1021/np050498o
Chlorocebus sabaeus	Vero	CC50	820.0	ug.mL-1	10.1021/jm9705869
Chlorocebus sabaeus	Vero	CC50	820.0	ug.mL-1	10.1021/jm9904194
Chlorocebus sabaeus	Vero	CC50	1275.0	ug.mL-1	10.1007/s00044-011-9574-8
Chlorocebus sabaeus	Vero	CC50	5000.0	nM	10.1016/s0960-894x(00)00061-5
Chlorocebus sabaeus	Vero	CC50	50000.0	nM	10.1016/j.ejmech.2013.01.015
Chlorocebus sabaeus	Vero	CC50	100000.0	nM	10.1016/0960-894X(95)00208-B
Chlorocebus sabaeus	Vero	CC50	100000.0	nM	10.1016/j.bmc.2009.05.020
Chlorocebus sabaeus	Vero	CC50	100000.0	nM	10.1016/j.bmc.2010.02.037
Chlorocebus sabaeus	Vero	CC50	100000.0	nM	10.1016/j.bmc.2011.10.009
Chlorocebus sabaeus	Vero	CC50	100000.0	nM	10.1016/j.bmcl.2007.10.065
Chlorocebus sabaeus	Vero	CC50	100000.0	nM	10.1016/j.ejmech.2012.03.038
Chlorocebus sabaeus	Vero	CC50	100000.0	nM	10.1016/j.ejmech.2022.114443
Chlorocebus sabaeus	Vero	CC50	100000.0	nM	10.1021/acs.jnatprod.1c00400
Chlorocebus sabaeus	Vero	CC50	100000.0	nM	10.1021/jm050162b
Chlorocebus sabaeus	Vero	CC50	122000.0	ug.mL-1	10.1021/np010207l
Chlorocebus sabaeus	Vero	CC50	126000.0	nM	10.1016/j.bmc.2007.09.032
Chlorocebus sabaeus	Vero	CC50	200000.0	nM	10.1016/j.bmcl.2007.02.079
Chlorocebus sabaeus	Vero	CC50	200000.0	nM	10.1016/j.bmcl.2007.11.120
Chlorocebus sabaeus	Vero	CC50	200000.0	nM	10.1016/j.bmcl.2009.08.009
Chlorocebus sabaeus	Vero	CC50	200000.0	nM	10.1016/j.bmcl.2011.01.098
Chlorocebus sabaeus	Vero	CC50	200000.0	nM	10.1016/j.bmcl.2012.05.079
Chlorocebus sabaeus	Vero	CC50	200000.0	nM	10.1016/j.bmcl.2012.10.047
Chlorocebus sabaeus	Vero	CC50	200000.0	nM	10.1021/acs.jnatprod.7b00620
Chlorocebus sabaeus	Vero	CC50	200000.0	nM	10.1021/jm040149b
Chlorocebus sabaeus	Vero	CC50	400000.0	nM	10.1021/jm030206l
Chlorocebus sabaeus	Vero	CC50	860000.0	nM	10.1016/j.bmc.2011.02.007
Chlorocebus sabaeus	Vero	CC50	890000.0	nM	10.1128/aac.01284-06
Chlorocebus sabaeus	Vero	CC50	960000.0	nM	10.1007/s00044-007-9035-6
Chlorocebus sabaeus	Vero	CC50	960000.0	nM	10.1016/j.bmcl.2005.10.111
Chlorocebus sabaeus	Vero	CC50	1000000.0	nM	10.1016/j.bmcl.2015.05.039
Chlorocebus sabaeus	Vero	CC50	1000000.0	nM	10.1016/j.bmcl.2017.01.032
Chlorocebus sabaeus	Vero	CC50	1100000.0	ug.mL-1	10.1016/j.bmc.2020.115378
Chlorocebus sabaeus	Vero	CC50	2000000.0	nM	10.1016/j.bmc.2012.08.008
Chlorocebus sabaeus	Vero	CC50	2000000.0	nM	10.1016/j.ejmech.2019.01.076
Chlorocebus sabaeus	Vero	CC50	nan	None	10.1021/acs.jnatprod.7b00193
Chlorocebus sabaeus	Vero	CCID50	500.0	uM	10.1021/jm950029r
Chlorocebus sabaeus	Vero	CD50	50.0	uM	10.1021/jm00027a009
Chlorocebus sabaeus	Vero	Cytotoxicity	400.0	None	10.1021/jm991171l
Chlorocebus sabaeus	Vero	EC50	0.32	ug.mL-1	10.1016/0960-894X(95)00395-A
Chlorocebus sabaeus	Vero	EC50	0.39	ug.mL-1	10.1016/0960-894X(95)00395-A
Chlorocebus sabaeus	Vero	EC50	0.5	ug.mL-1	10.1016/s0960-894x(01)00589-3
Chlorocebus sabaeus	Vero	EC50	40.0	ug.mL-1	10.1016/s0960-894x(01)00589-3
Chlorocebus sabaeus	Vero	EC50	3000.0	nM	10.1016/0960-894X(95)00208-B
Chlorocebus sabaeus	Vero	EC50	3000.0	nM	10.1016/s0960-894x(00)00061-5
Chlorocebus sabaeus	Vero	EC50	6000.0	nM	10.1016/0960-894X(95)00208-B
Chlorocebus sabaeus	Vero	EC50	6000.0	nM	10.1016/s0960-894x(00)00373-5
Chlorocebus sabaeus	Vero	ED50	0.04	uM	10.1021/jm00083a017
Chlorocebus sabaeus	Vero	ED50	0.5	uM	10.1021/jm00027a009
Chlorocebus sabaeus	Vero	ED50	1300.0	uM	10.1021/jm00083a017
Chlorocebus sabaeus	Vero	IC50	0.1	ug.mL-1	10.1016/S0960-894X(01)80693-4
Chlorocebus sabaeus	Vero	IC50	0.5	ug.mL-1	10.1016/S0960-894X(01)80693-4
Chlorocebus sabaeus	Vero	IC50	0.81	ug.mL-1	10.1021/jm9705869
Chlorocebus sabaeus	Vero	IC50	1.5	ug.mL-1	10.1016/S0960-894X(01)80236-5
Chlorocebus sabaeus	Vero	IC50	50.0	ug.mL-1	10.1016/S0960-894X(97)00365-X
Chlorocebus sabaeus	Vero	IC50	100.0	nM	10.1021/jm00146a002
Chlorocebus sabaeus	Vero	IC50	100.0	ug.mL-1	10.1021/np960613i
Chlorocebus sabaeus	Vero	IC50	1200.0	nM	10.1021/jm00094a005
Chlorocebus sabaeus	Vero	IC50	2100.0	nM	10.1021/jm050162b
Chlorocebus sabaeus	Vero	IC50	2400.0	nM	10.1021/jm050162b
Chlorocebus sabaeus	Vero	IC50	2500.0	nM	10.1021/jm00392a020
Chlorocebus sabaeus	Vero	IC50	2800.0	nM	10.1021/jm050162b
Chlorocebus sabaeus	Vero	IC50	3500.0	nM	10.1021/jm050162b
Chlorocebus sabaeus	Vero	IC50	3800.0	nM	10.1021/jm00392a020
Chlorocebus sabaeus	Vero	IC50	4400.0	nM	10.1021/jm050162b
Chlorocebus sabaeus	Vero	IC50	5400.0	nM	10.1021/jm050162b
Chlorocebus sabaeus	Vero	IC50	6660.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	6700.0	nM	10.1021/jm00163a031
Chlorocebus sabaeus	Vero	IC50	7540.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	10000.0	nM	10.1021/jm050162b
Chlorocebus sabaeus	Vero	IC50	37800.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	44400.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	50000.0	nM	10.1016/s0960-894x(00)00418-2
Chlorocebus sabaeus	Vero	IC50	62800.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	88800.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	111000.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	130700.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	138400.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	189800.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	378800.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	444000.0	nM	10.1021/jm980182w
Chlorocebus sabaeus	Vero	IC50	1700000.0	nM	10.1016/j.ejmech.2015.11.009
Chlorocebus sabaeus	Vero	IC50	nan	None	10.1016/j.ejmech.2015.11.009
Chlorocebus sabaeus	Vero	ID50	0.01	ug ml-1	10.1021/jm00125a003
Chlorocebus sabaeus	Vero	ID50	0.01	ug ml-1	10.1021/jm00164a039
Chlorocebus sabaeus	Vero	ID50	0.2	ug ml-1	10.1016/S0960-894X(01)80719-8
Chlorocebus sabaeus	Vero	ID50	0.5	ug ml-1	10.1021/jm00111a052
Chlorocebus sabaeus	Vero	ID50	0.5	uM	10.1021/jm00158a011
Chlorocebus sabaeus	Vero	ID50	0.5	uM	10.1021/jm00381a015
Chlorocebus sabaeus	Vero	ID50	0.6	ug ml-1	10.1016/S0960-894X(01)80719-8
Chlorocebus sabaeus	Vero	ID50	0.9	ug ml-1	10.1021/jm00166a020
Chlorocebus sabaeus	Vero	ID50	2.4	ug ml-1	10.1021/jm00111a052
Chlorocebus sabaeus	Vero	ID50	100.0	ug ml-1	10.1021/jm00111a052
Chlorocebus sabaeus	Vero	ID50	100.0	ug ml-1	10.1021/jm00166a019
Chlorocebus sabaeus	Vero	ID50	300.0	ug ml-1	10.1016/S0960-894X(01)80719-8
Chlorocebus sabaeus	Vero	ID50	300.0	ug ml-1	10.1021/jm00107a006
Chlorocebus sabaeus	Vero	ID50	500.0	None	10.1021/jm00113a016
Chlorocebus sabaeus	Vero	ID50	1100.0	uM	10.1021/jm00147a020
Chlorocebus sabaeus	Vero	MCC	nan	None	10.1021/jm050772b
Chlorocebus sabaeus	Vero	MIC	0.14	ug.mL-1	10.1021/jm00063a008
Chlorocebus sabaeus	Vero	MIC	0.29	ug.mL-1	10.1021/jm00063a008
Chlorocebus sabaeus	Vero	MIC	1.3	ug.mL-1	10.1021/jm00014a006
Chlorocebus sabaeus	Vero	MIC	1.3	ug.mL-1	10.1021/jm00063a008
Chlorocebus sabaeus	Vero	MIC	7.8	ug.mL-1	10.1021/jm00063a008
Chlorocebus sabaeus	Vero	MIC	11.0	ug.mL-1	10.1021/jm00063a008
Chlorocebus sabaeus	Vero	MIC	43.0	ug.mL-1	10.1021/jm00063a008
Chlorocebus sabaeus	Vero	MIC	77.0	ug.mL-1	10.1021/jm00063a008
Chlorocebus sabaeus	Vero	MIC50	4.3	ug.mL-1	10.1021/jm00388a036
Chlorocebus sabaeus	Vero	MIC50	1800.0	nM	10.1021/jm00113a016
Chlorocebus sabaeus	Vero	MNCC	1.11	mM	10.1021/np800760p
Chlorocebus sabaeus	Vero	MNCC	1.11	mM	10.1021/np900290s
Chlorocebus sabaeus	Vero	MNCC	1.11	mM	10.1021/np900530n
Chlorocebus sabaeus	Vero	MNCC	nan	None	10.1007/s00044-010-9338-x
Chlorocebus sabaeus	Vero	MNCC	nan	None	10.1021/np050498o
Chlorocebus sabaeus	Vero	MNTD	40.0	ug ml-1	10.1021/jm00172a026
Chlorocebus sabaeus	Vero	MTC	255.2	ug ml-1	10.1021/jm00166a020
Chlorocebus sabaeus	Vero	MTL	200.0	ug ml-1	10.1021/jm00014a006
Chlorocebus sabaeus	Vero	Selectivity index	880.0	None	10.1016/j.bmcl.2005.10.111
Chlorocebus sabaeus	Vero	TC50	100.0	uM	10.1021/acs.jnatprod.7b01074
Chlorocebus sabaeus	Vero	TC50	100.0	umol/L	10.1021/acs.jnatprod.6b00585
Chlorocebus sabaeus	Vero	TD50	240.0	ug ml-1	10.1021/jm00172a026
Chlorocebus sabaeus	Vero	Therapeutic index	240.3	None	10.1021/jm00166a020
Chlorocebus sabaeus	Vero	Virus rating	6.2	None	10.1021/jm00166a020
Chlorocebus sabaeus	Vero	Zone of inhibition	11.0	mM	10.1021/jm00146a002
Chlorocebus sabaeus	Vero 76	CC50	100000.0	nM	10.1016/j.ejmech.2017.09.060
Chlorocebus sabaeus	Vero C1008	CC100	nan	None	10.1021/acs.jnatprod.2c00464
Chlorocebus sabaeus	Vero C1008	MCC	444000.0	nM	10.1016/j.bmcl.2017.03.100
Coxsackievirus	Coxsackievirus	EC50	nan	nM	10.1021/jm0493966
Coxsackievirus B2	Coxsackievirus B2	EC50	100000.0	nM	10.1016/j.bmc.2009.05.020
Coxsackievirus B2	Coxsackievirus B2	EC50	100000.0	nM	10.1016/j.bmc.2010.02.037
Coxsackievirus B2	Coxsackievirus B2	EC50	nan	None	10.1016/j.ejmech.2016.03.080
Coxsackievirus B3	Coxsackievirus B3	IC50	25.0	ug.mL-1	10.1021/np050498o
Coxsackievirus B4	Coxsackievirus B4	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Coxsackievirus B4	Coxsackievirus B4	Inhibition	nan	%	10.1016/j.bmc.2013.07.031
Coxsackievirus B4	Coxsackievirus B4	MIC50	nan	None	10.1021/jm050772b
Coxsackievirus B5	Coxsackievirus B5	EC50	100000.0	nM	10.1016/j.bmc.2014.06.043
Coxsackievirus B5	Coxsackievirus B5	EC50	100000.0	nM	10.1016/j.bmc.2015.09.035
Coxsackievirus B5	Coxsackievirus B5	EC50	100000.0	nM	10.1016/j.ejmech.2015.10.002
Cryptococcus neoformans	Cryptococcus neoformans	Inhibition	-1.27	%	10.6019/CHEMBL4513141
Cryptococcus neoformans	Cryptococcus neoformans	MIC	20000.0	nM	10.6019/CHEMBL4513161
Cytomegalovirus	Cytomegalovirus	EC50	16.0	ug.mL-1	10.1016/s0960-894x(01)00270-0
Cytomegalovirus	Cytomegalovirus	EC50	nan	ug.mL-1	10.1016/s0960-894x(01)00270-0
Cytomegalovirus	Cytomegalovirus	EC50	nan	ug.mL-1	10.1021/jm040869i
Cytomegalovirus	Cytomegalovirus	EC50	nan	None	10.1021/acsmedchemlett.0c00090
Cytomegalovirus	Cytomegalovirus	IC50	63000.0	nM	10.1021/jm00403a005
Cytomegalovirus	Cytomegalovirus	IC50	93000.0	nM	10.1021/jm00062a006
Cytomegalovirus	Cytomegalovirus	IC50	nan	ug.mL-1	10.1016/s0960-894x(01)00270-0
Cytomegalovirus	Cytomegalovirus	MIC	20.0	ug.mL-1	10.1021/jm00402a017
Cytomegalovirus	Cytomegalovirus	MIC	25.0	ug.mL-1	10.1021/jm00402a017
Cytomegalovirus	Cytomegalovirus	MIC	nan	ug.mL-1	10.1016/S0960-894X(96)00244-2
dengue virus type 2	dengue virus type 2	Activity	nan	None	10.1016/j.ejmech.2015.11.009
dengue virus type 2	dengue virus type 2	EC	nan	None	10.1021/acs.jnatprod.2c00464
dengue virus type 2	dengue virus type 2	EC50	nan	None	10.1016/j.bmc.2015.09.035
dengue virus type 2	dengue virus type 2	EC50	nan	None	10.1016/j.ejmech.2015.11.009
dengue virus type 2	dengue virus type 2	MNTD	nan	None	10.1016/j.ejmech.2015.11.009
Duck hepatitis B virus	Duck hepatitis B virus	Inhibition	nan	%	10.1016/s0960-894x(01)00589-3
Echovirus E9	Echovirus E9	Inhibition	nan	%	10.1016/j.bmc.2013.07.031
Enterovirus E	Enterovirus E	Activity	nan	None	10.1016/j.ejmech.2021.113738
Enterovirus E	Enterovirus E	EC50	222.0	None	10.1016/j.ejmech.2021.113738
Equid alphaherpesvirus 1	Equid alphaherpesvirus 1	EC50	1.7	ug.mL-1	10.1128/aac.00116-07
Equid alphaherpesvirus 1	Equid alphaherpesvirus 1	MIC	0.2	ug.mL-1	10.1021/jm00402a017
Equus caballus	Equus caballus	Activity	nan	None	10.1128/aac.00116-07
Equus caballus	Equus caballus	AUC	1160.0	ng.hr.mL-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	AUC	18000.0	ng.hr.mL-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	AUC	19200.0	ng.hr.mL-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	AUC	37300.0	ng.hr.mL-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	CL	0.3	L/hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	CL	6.833	mL.min-1.kg-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	CL	9.833	mL.min-1.kg-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	Cmax	1465.3	nM	10.1128/aac.00116-07
Equus caballus	Equus caballus	Cmax	46179.12	nM	10.1128/aac.00116-07
Equus caballus	Equus caballus	Cmax	47511.21	nM	10.1128/aac.00116-07
Equus caballus	Equus caballus	Cmax	205141.87	nM	10.1128/aac.00116-07
Equus caballus	Equus caballus	Cp	50.0	ng/ml	10.1128/aac.00116-07
Equus caballus	Equus caballus	F	2.8	%	10.1128/aac.00116-07
Equus caballus	Equus caballus	F	3.13	%	10.1128/aac.00116-07
Equus caballus	Equus caballus	F	7.52	%	10.1128/aac.00116-07
Equus caballus	Equus caballus	fAUC	3530.0	ng.hr.mL-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	fAUC	24600.0	ng.hr.mL-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	fCmax	0.4	ug ml-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	fCmax	10.5	ug ml-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	MRT	5.38	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	MRT	7.09	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	MRT	23.1	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	T1/2	0.1	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	T1/2	0.23	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	T1/2	1.23	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	T1/2	1.56	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	T1/2	5.05	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	T1/2	9.6	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	T1/2	11.9	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	T1/2	13.5	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	Tmax	1.04	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	Tmax	1.06	hr	10.1128/aac.00116-07
Equus caballus	Equus caballus	Vd	0.27	L.kg-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	Vd	0.36	L.kg-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	Vdss	2.96	L.kg-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	Vdss	3.54	L.kg-1	10.1128/aac.00116-07
Equus caballus	Equus caballus	Vdss	9.81	L.kg-1	10.1128/aac.00116-07
Equus caballus	Ferritin light chain	Potency	0.08913	nM	None
Escherichia coli	Escherichia coli	Inhibition	4.79	%	10.6019/CHEMBL4513141
Escherichia coli	Escherichia coli	MIC	20000.0	nM	10.6019/CHEMBL4513161
Felid alphaherpesvirus 1	Felid alphaherpesvirus 1	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Felid alphaherpesvirus 1	Felid alphaherpesvirus 1	EC50	1000.0	nM	10.1016/j.bmc.2011.05.037
Felid alphaherpesvirus 1	Felid alphaherpesvirus 1	EC50	100000.0	nM	10.1016/j.ejmech.2013.09.047
Felid alphaherpesvirus 1	Felid alphaherpesvirus 1	EC50	nan	None	10.1016/j.bmc.2011.04.016
Felid alphaherpesvirus 1	Felid alphaherpesvirus 1	EC50	nan	None	10.1016/j.ejmech.2012.07.027
Feline coronavirus	Feline coronavirus	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Hepacivirus hominis	Hepatitis C virus	Activity	nan	None	10.1021/jm900126v
Hepacivirus hominis	Hepatitis C virus	EC50	nan	nM	10.1021/jm034265a
Hepatitis B virus	Hepatitis B virus	Activity	nan	None	10.1021/jm900126v
Hepatitis B virus	Hepatitis B virus	EC50	20.0	nM	10.1021/jm034265a
Hepatitis B virus	Hepatitis B virus	EC50	nan	nM	10.1016/s0960-894x(00)00418-2
Hepatitis B virus	Hepatitis B virus	IC50	50.0	ug.mL-1	10.1016/s0960-894x(01)00270-0
Hepatitis B virus	Hepatitis B virus	IC50	1000000.0	nM	10.1016/j.bmcl.2012.12.097
Hepatovirus A	Hepatovirus A	IC50	30.6	ug.mL-1	10.1016/j.ejmech.2019.02.048
Hepatovirus A	Hepatovirus A	IC50	33.5	ug.mL-1	10.1016/j.ejmech.2019.02.048
Hepatovirus A	Hepatovirus A	IC50	35.6	ug.mL-1	10.1016/j.ejmech.2019.02.048
Herpes simplex virus (type 1 / strain 17)	Human herpesvirus 1 DNA polymerase	DP	9.0	%	10.1021/jm00120a010
Herpes simplex virus (type 1 / strain 17)	Human herpesvirus 1 DNA polymerase	Inhibition	79.0	%	10.1021/jm00120a010
Herpes simplex virus (type 1 / strain 17)	Human herpesvirus 1 DNA polymerase	MP	3.0	%	10.1021/jm00120a010
Herpes simplex virus (type 1 / strain 17)	Human herpesvirus 1 DNA polymerase	MP	17.0	%	10.1021/jm00120a010
Herpes simplex virus (type 1 / strain 17)	Human herpesvirus 1 DNA polymerase	TP	60.0	%	10.1021/jm00120a010
Homo sapiens	A549	CC20	196.08	uM	10.1016/j.ejmech.2021.113738
Homo sapiens	A549	CC50	1555600.0	nM	10.1016/j.ejmech.2021.113738
Homo sapiens	Acetylcholinesterase	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Acetylcholinesterase	IC50	nan	None	None
Homo sapiens	Acetylcholinesterase	Ki	nan	None	None
Homo sapiens	Adenosine A1 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Adenosine A1 receptor	IC50	nan	None	None
Homo sapiens	Adenosine A1 receptor	Ki	nan	None	None
Homo sapiens	Adenosine A2a receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Adenosine A2a receptor	IC50	nan	None	None
Homo sapiens	Adenosine A2a receptor	Ki	nan	None	None
Homo sapiens	Adenosine A3 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Adenosine A3 receptor	IC50	nan	None	None
Homo sapiens	Adenosine A3 receptor	Ki	nan	None	None
Homo sapiens	Alpha-1a adrenergic receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-1a adrenergic receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-1d adrenergic receptor	IC50	nan	None	None
Homo sapiens	Alpha-1d adrenergic receptor	Ki	nan	None	None
Homo sapiens	Alpha-2a adrenergic receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2a adrenergic receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2a adrenergic receptor	IC50	nan	None	None
Homo sapiens	Alpha-2a adrenergic receptor	Ki	nan	None	None
Homo sapiens	Alpha-2b adrenergic receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2b adrenergic receptor	IC50	nan	None	None
Homo sapiens	Alpha-2b adrenergic receptor	Ki	nan	None	None
Homo sapiens	Alpha-2c adrenergic receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2c adrenergic receptor	IC50	nan	None	None
Homo sapiens	Alpha-2c adrenergic receptor	Ki	nan	None	None
Homo sapiens	Androgen Receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Angiotensin II type 2 (AT-2) receptor	IC50	nan	None	None
Homo sapiens	Angiotensin II type 2 (AT-2) receptor	Ki	nan	None	None
Homo sapiens	ATP-dependent DNA helicase Q1	Potency	794.3	nM	None
Homo sapiens	Beta-1 adrenergic receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Beta-1 adrenergic receptor	IC50	nan	None	None
Homo sapiens	Beta-1 adrenergic receptor	Ki	nan	None	None
Homo sapiens	Beta-2 adrenergic receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Beta-2 adrenergic receptor	IC50	nan	None	None
Homo sapiens	Beta-2 adrenergic receptor	Ki	nan	None	None
Homo sapiens	Beta-3 adrenergic receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Beta-3 adrenergic receptor	IC50	nan	None	None
Homo sapiens	Beta-3 adrenergic receptor	Ki	nan	None	None
Homo sapiens	Bile salt export pump	IC50	133000.0	nM	10.1093/toxsci/kft176
Homo sapiens	Bile salt export pump	IC50	135000.0	nM	10.1093/toxsci/kfq269
Homo sapiens	Bile salt export pump	IC50	1000000.0	nM	10.1124/dmd.111.040758
Homo sapiens	Bile salt export pump	IC50	1000000.0	nM	10.1124/dmd.112.047068
Homo sapiens	Bloom syndrome protein	Potency	501.2	nM	None
Homo sapiens	Bradykinin B1 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Bradykinin B2 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Bradykinin B2 receptor	IC50	nan	None	None
Homo sapiens	Bradykinin B2 receptor	Ki	nan	None	None
Homo sapiens	Caco-2	logPapp	-6.15	None	10.1016/j.bmc.2009.08.022
Homo sapiens	Caco-2	logPapp	-6.15	None	10.1016/j.bmc.2011.03.011
Homo sapiens	Calcitonin receptor	IC50	nan	None	None
Homo sapiens	Calcitonin receptor	Ki	nan	None	None
Homo sapiens	Canalicular multispecific organic anion transporter 1	IC50	133000.0	nM	10.1093/toxsci/kft176
Homo sapiens	Canalicular multispecific organic anion transporter 2	IC50	133000.0	nM	10.1093/toxsci/kft176
Homo sapiens	Cannabinoid CB1 receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Cannabinoid CB1 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Cannabinoid CB1 receptor	IC50	nan	None	None
Homo sapiens	Cannabinoid CB1 receptor	Ki	nan	None	None
Homo sapiens	Carbonic anhydrase II	IC50	nan	None	None
Homo sapiens	Carbonic anhydrase II	Ki	nan	None	None
Homo sapiens	Caspase-1	IC50	nan	None	None
Homo sapiens	Caspase-1	Ki	nan	None	None
Homo sapiens	Cathepsin G	IC50	nan	None	None
Homo sapiens	Cathepsin G	Ki	nan	None	None
Homo sapiens	C-C chemokine receptor type 2	IC50	nan	None	None
Homo sapiens	C-C chemokine receptor type 2	Ki	nan	None	None
Homo sapiens	C-C chemokine receptor type 4	IC50	nan	None	None
Homo sapiens	C-C chemokine receptor type 4	Ki	nan	None	None
Homo sapiens	C-C chemokine receptor type 5	IC50	nan	None	None
Homo sapiens	C-C chemokine receptor type 5	Ki	nan	None	None
Homo sapiens	CCRF-CEM	CC50	200000.0	nM	10.1016/j.bmcl.2003.09.033
Homo sapiens	CCRF-CEM	EC50	200000.0	nM	10.1016/j.bmcl.2003.09.033
Homo sapiens	CCRF-CEM	IC50	250000.0	nM	10.1021/jm9007856
Homo sapiens	CCRF-CEM	IC50	440000.0	nM	10.1016/s0960-894x(01)00735-1
Homo sapiens	CCRF-CEM	IC50	nan	nM	10.1016/s0960-894x(01)00735-1
Homo sapiens	CCRF-CEM	ID50	100.0	None	10.1021/jm990543n
Homo sapiens	CCRF-CEM	ID50	200.0	None	10.1021/jm990543n
Homo sapiens	CCRF-CEM	ID50	nan	None	10.1021/jm034265a
Homo sapiens	CCRF-HSB-2	IC50	100.0	ug.mL-1	10.1021/jm9701536
Homo sapiens	CDGSH iron-sulfur domain-containing protein 1	IC50	nan	None	10.1016/j.bmcl.2016.09.009
Homo sapiens	CDGSH iron-sulfur domain-containing protein 1	Ki	nan	None	10.1016/j.bmcl.2016.09.009
Homo sapiens	Cerebroside-sulfatase	Potency	23934.1	nM	None
Homo sapiens	Cholecystokinin A receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Cholecystokinin A receptor	IC50	nan	None	None
Homo sapiens	Cholecystokinin A receptor	Ki	nan	None	None
Homo sapiens	Cholecystokinin B receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Corticotropin releasing factor receptor 1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Corticotropin releasing factor receptor 2	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Cyclooxygenase-1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Cyclooxygenase-1	IC50	nan	None	None
Homo sapiens	Cyclooxygenase-1	Ki	nan	None	None
Homo sapiens	Cyclooxygenase-2	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Cyclooxygenase-2	IC50	nan	None	None
Homo sapiens	Cyclooxygenase-2	Ki	nan	None	None
Homo sapiens	Cysteinyl leukotriene receptor 1	IC50	nan	None	None
Homo sapiens	Cysteinyl leukotriene receptor 1	Ki	nan	None	None
Homo sapiens	Cytochrome P450 1A2	AC50	nan	None	None
Homo sapiens	Cytochrome P450 1A2	Activity	nan	None	None
Homo sapiens	Cytochrome P450 1A2	IC50	nan	None	None
Homo sapiens	Cytochrome P450 1A2	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2A6	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2A6	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2C19	AC50	nan	None	None
Homo sapiens	Cytochrome P450 2C19	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2C19	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2C9	AC50	nan	None	None
Homo sapiens	Cytochrome P450 2C9	FC	1.0	None	10.1016/j.bmcl.2016.06.088
Homo sapiens	Cytochrome P450 2C9	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2C9	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2D6	AC50	nan	None	None
Homo sapiens	Cytochrome P450 2D6	FC	1.0	None	10.1016/j.bmcl.2016.06.088
Homo sapiens	Cytochrome P450 2D6	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2D6	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2E1	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2E1	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2J2	IC50	50000.0	nM	10.1124/dmd.112.048264
Homo sapiens	Cytochrome P450 3A4	AC50	nan	None	None
Homo sapiens	Cytochrome P450 3A4	FC	1.0	None	10.1016/j.bmcl.2016.06.088
Homo sapiens	Cytochrome P450 3A4	IC50	nan	None	None
Homo sapiens	Cytochrome P450 3A4	Ki	nan	None	None
Homo sapiens	Daudi	CC50	100000.0	nM	10.1021/jm0607404
Homo sapiens	Daudi	CC50	222000.0	nM	10.1021/jm040093l
Homo sapiens	Daudi	CC50	222000.0	nM	10.1021/jm040149b
Homo sapiens	Delta opioid receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Delta opioid receptor	IC50	nan	None	None
Homo sapiens	Delta opioid receptor	Ki	nan	None	None
Homo sapiens	DNA polymerase alpha subunit	Inhibition	37.0	%	10.1021/jm00155a039
Homo sapiens	Dopamine D1 receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine D1 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine D1 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D1 receptor	Ki	nan	None	None
Homo sapiens	Dopamine D2 receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine D2 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D2 receptor	Ki	nan	None	None
Homo sapiens	Dopamine D3 receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine D3 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine D3 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D3 receptor	Ki	nan	None	None
Homo sapiens	Dopamine D4 receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine D4 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D4 receptor	Ki	nan	None	None
Homo sapiens	Dopamine transporter	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine transporter	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine transporter	IC50	nan	None	None
Homo sapiens	Dopamine transporter	Ki	nan	None	None
Homo sapiens	E6SM	CC50	400.0	ug.mL-1	10.1021/jm9507901
Homo sapiens	E6SM	Cytotoxicity	50.0	None	10.1021/jm991171l
Homo sapiens	E6SM	EC50	0.07	ug.mL-1	10.1021/jm049806q
Homo sapiens	E6SM	EC50	0.38	ug.mL-1	10.1021/jm049806q
Homo sapiens	E6SM	EC50	48.0	ug.mL-1	10.1021/jm049806q
Homo sapiens	E6SM	MCC	200.0	ug.mL-1	10.1021/jm980287z
Homo sapiens	E6SM	MCC	400.0	ug.mL-1	10.1016/j.ejmech.2007.04.010
Homo sapiens	E6SM	MCC	400.0	ug.mL-1	10.1016/s0960-894x(01)00838-1
Homo sapiens	E6SM	MCC	400.0	ug.mL-1	10.1021/jm00086a015
Homo sapiens	E6SM	MCC	400.0	ug.mL-1	10.1021/jm0108404
Homo sapiens	E6SM	MCC	400.0	ug.mL-1	10.1021/jm025569k
Homo sapiens	E6SM	MCC	400.0	ug.mL-1	10.1021/jm049806q
Homo sapiens	E6SM	MCC	400.0	ug.mL-1	10.1021/jm0701472
Homo sapiens	E6SM	MIC	0.015	ug.mL-1	10.1021/jm00086a015
Homo sapiens	E6SM	MIC	0.02	ug.mL-1	10.1021/jm00086a015
Homo sapiens	E6SM	MIC	0.04	ug.mL-1	10.1021/jm00086a015
Homo sapiens	E6SM	MIC	0.04	ug.mL-1	10.1021/jm960770e
Homo sapiens	E6SM	MIC	0.07	ug.mL-1	10.1021/jm00086a015
Homo sapiens	E6SM	MIC	0.07	ug.mL-1	10.1021/jm960770e
Homo sapiens	E6SM	MIC	0.075	ug.mL-1	10.1021/jm980287z
Homo sapiens	E6SM	MIC	0.077	ug.mL-1	10.1021/jm0108404
Homo sapiens	E6SM	MIC	0.08	ug.mL-1	10.1016/s0960-894x(01)00838-1
Homo sapiens	E6SM	MIC	0.1	ug.mL-1	10.1021/jm980287z
Homo sapiens	E6SM	MIC	0.38	ug.mL-1	10.1021/jm980287z
Homo sapiens	E6SM	MIC	0.384	ug.mL-1	10.1021/jm0108404
Homo sapiens	E6SM	MIC	1.92	ug.mL-1	10.1021/jm980287z
Homo sapiens	E6SM	MIC	10.0	ug.mL-1	10.1021/jm00086a015
Homo sapiens	E6SM	MIC	48.0	ug.mL-1	10.1016/s0960-894x(01)00838-1
Homo sapiens	E6SM	MIC	48.0	ug.mL-1	10.1021/jm0108404
Homo sapiens	E6SM	MIC	70.0	ug.mL-1	10.1021/jm00086a015
Homo sapiens	E6SM	MIC	70.0	ug.mL-1	10.1021/jm960770e
Homo sapiens	E6SM	MIC	200.0	ug.mL-1	10.1021/jm960770e
Homo sapiens	E6SM	MIC	350.0	ug.mL-1	10.1021/jm00045a025
Homo sapiens	E6SM	MIC	400.0	ug.mL-1	10.1016/s0960-894x(01)00838-1
Homo sapiens	E6SM	MIC	400.0	ug.mL-1	10.1021/jm0108404
Homo sapiens	E6SM	MIC	400.0	ug.mL-1	10.1021/jm960770e
Homo sapiens	E6SM	MIC	500000.0	nM	10.1016/j.bmc.2006.10.046
Homo sapiens	E6SM	MIC	500000.0	nM	10.1021/np060435l
Homo sapiens	E6SM	VSV	400.0	None	10.1021/jm00086a015
Homo sapiens	E6SM	VV	400.0	None	10.1021/jm00086a015
Homo sapiens	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Potency	15848.9	nM	None
Homo sapiens	Endothelin receptor ET-A	AC50	8940.1	nM	10.1038/s41467-023-40064-9
Homo sapiens	Endothelin receptor ET-A	IC50	nan	None	None
Homo sapiens	Endothelin receptor ET-A	Ki	nan	None	None
Homo sapiens	Endothelin receptor ET-B	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Epidermal growth factor receptor erbB1	IC50	nan	None	None
Homo sapiens	Epidermal growth factor receptor erbB1	Ki	nan	None	None
Homo sapiens	Equilibrative nucleoside transporter 1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Estrogen receptor alpha	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Estrogen receptor alpha	IC50	nan	None	None
Homo sapiens	Estrogen receptor alpha	Ki	nan	None	None
Homo sapiens	Estrogen receptor beta	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Estrogen receptor beta	IC50	nan	None	None
Homo sapiens	Estrogen receptor beta	Ki	nan	None	None
Homo sapiens	F2002 cell line	IC50	nan	ug.mL-1	10.1016/S0960-894X(01)80693-4
Homo sapiens	GABA-B receptor 1	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Gastric inhibitory polypeptide receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Ghrelin receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Glucagon receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Glucocorticoid receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Glucocorticoid receptor	IC50	nan	None	None
Homo sapiens	Glucocorticoid receptor	Ki	nan	None	None
Homo sapiens	HEK293	CC50	20000.0	nM	10.6019/CHEMBL4513161
Homo sapiens	HEK293	Potency	2908.1	nM	None
Homo sapiens	HEL	Activity	100.0	ug ml-1	10.1021/jm061281+
Homo sapiens	HEL	Activity	173.5	ug ml-1	10.1021/jm061281+
Homo sapiens	HEL	CC	100.0	ug ml-1	10.1021/jm981051y
Homo sapiens	HEL	CC50	50.0	ug.mL-1	10.1016/S0960-894X(01)80538-2
Homo sapiens	HEL	CC50	118.0	ug.mL-1	10.1021/jm051023x
Homo sapiens	HEL	CC50	120.0	ug.mL-1	10.1007/s00044-011-9776-0
Homo sapiens	HEL	CC50	137.0	ug.mL-1	10.1016/j.bmc.2008.09.027
Homo sapiens	HEL	CC50	200.0	ug.mL-1	10.1016/j.bmc.2007.03.061
Homo sapiens	HEL	CC50	200.0	ug.mL-1	10.1016/j.ejmech.2007.04.010
Homo sapiens	HEL	CC50	200.0	ug.mL-1	10.1016/s0960-894x(02)00535-8
Homo sapiens	HEL	CC50	200.0	ug.mL-1	10.1021/jm00005a010
Homo sapiens	HEL	CC50	200.0	ug.mL-1	10.1021/jm040869i
Homo sapiens	HEL	CC50	200.0	ug.mL-1	10.1021/jm980327z
Homo sapiens	HEL	CC50	212.0	ug.mL-1	10.1021/jm0707166
Homo sapiens	HEL	CC50	130000.0	nM	10.1016/j.ejmech.2010.12.017
Homo sapiens	HEL	CC50	134000.0	nM	10.1016/j.ejmech.2012.08.042
Homo sapiens	HEL	CC50	200000.0	nM	10.1016/s0960-894x(00)00193-1
Homo sapiens	HEL	CC50	200000.0	nM	10.1016/s0960-894x(00)00672-7
Homo sapiens	HEL	CC50	200000.0	nM	10.1021/jm070357e
Homo sapiens	HEL	CC50	300000.0	nM	10.1016/j.ejmech.2020.112884
Homo sapiens	HEL	CC50	300000.0	nM	10.1016/j.ejmech.2021.113467
Homo sapiens	HEL	CC50	400000.0	nM	10.1016/j.bmc.2011.05.037
Homo sapiens	HEL	CC50	400000.0	nM	10.1016/s0960-894x(01)00471-1
Homo sapiens	HEL	CC50	400000.0	nM	10.1021/jm000118q
Homo sapiens	HEL	CC50	424000.0	nM	10.1021/acsmedchemlett.0c00485
Homo sapiens	HEL	CC50	440000.0	nM	10.1016/j.bmc.2014.02.056
Homo sapiens	HEL	CC50	440000.0	nM	10.1016/j.bmc.2015.09.033
Homo sapiens	HEL	CC50	440000.0	nM	10.1016/j.bmc.2017.06.046
Homo sapiens	HEL	CC50	440000.0	nM	10.1016/j.ejmech.2016.10.002
Homo sapiens	HEL	CC50	440000.0	nM	10.1016/j.ejmech.2018.01.086
Homo sapiens	HEL	CC50	440000.0	nM	10.1016/j.ejmech.2018.06.028
Homo sapiens	HEL	CC50	444000.0	nM	10.1016/j.ejmech.2017.12.018
Homo sapiens	HEL	CC50	444000.0	nM	10.1016/j.ejmech.2018.03.008
Homo sapiens	HEL	CC50	444000.0	nM	10.1021/acs.jmedchem.7b00416
Homo sapiens	HEL	CC50	444000.0	nM	10.1021/acsmedchemlett.0c00090
Homo sapiens	HEL	CC50	444000.0	nM	10.1021/acsmedchemlett.8b00079
Homo sapiens	HEL	CC50	444030.0	nM	10.1021/acs.jmedchem.2c00667
Homo sapiens	HEL	CC50	470000.0	nM	10.1016/j.ejmech.2012.04.001
Homo sapiens	HEL	CC50	500000.0	nM	10.1021/jm060030y
Homo sapiens	HEL	CC50	511000.0	nM	10.1021/jm0492812
Homo sapiens	HEL	CC50	545000.0	nM	10.1021/jm070324z
Homo sapiens	HEL	CC50	649000.0	nM	10.1021/jm0614329
Homo sapiens	HEL	CC50	733000.0	nM	10.1021/jm8014662
Homo sapiens	HEL	CC50	782000.0	nM	10.1016/j.ejmech.2009.03.005
Homo sapiens	HEL	CC50	787000.0	nM	10.1021/acs.jmedchem.7b01009
Homo sapiens	HEL	CC50	889000.0	nM	10.1021/jm050867d
Homo sapiens	HEL	CC50	890000.0	nM	10.1021/jm070210n
Homo sapiens	HEL	CC50	918000.0	nM	10.1016/j.ejmech.2012.07.027
Homo sapiens	HEL	CC50	1338000.0	nM	10.1016/j.bmc.2011.06.045
Homo sapiens	HEL	CC50	1350000.0	nM	10.1016/j.bmcl.2008.06.069
Homo sapiens	HEL	CC50	1421000.0	nM	10.1016/j.bmc.2011.04.016
Homo sapiens	HEL	CC50	1700000.0	nM	10.1016/j.bmcl.2003.09.033
Homo sapiens	HEL	CC50	1778000.0	nM	10.1016/j.bmcl.2009.12.102
Homo sapiens	HEL	CC50	nan	ug.mL-1	10.1016/s0960-894x(02)00535-8
Homo sapiens	HEL	Cytotoxicity	200.0	None	10.1021/jm991171l
Homo sapiens	HEL	EC50	0.03	ug.mL-1	10.1021/jm0707166
Homo sapiens	HEL	EC50	25.2	ug.mL-1	10.1021/jm0707166
Homo sapiens	HEL	EC50	320.0	nM	10.1016/j.bmcl.2003.09.033
Homo sapiens	HEL	EC50	900.0	nM	10.1021/jm049806q
Homo sapiens	HEL	EC50	1100.0	nM	10.1016/s0960-894x(01)00471-1
Homo sapiens	HEL	EC50	1300.0	nM	10.1016/j.bmcl.2003.09.033
Homo sapiens	HEL	EC50	1300.0	nM	10.1021/jm049806q
Homo sapiens	HEL	EC50	1500.0	nM	10.1016/s0960-894x(01)00471-1
Homo sapiens	HEL	EC50	4090.0	nM	10.1021/jm0108350
Homo sapiens	HEL	EC50	4530.0	nM	10.1021/jm0108350
Homo sapiens	HEL	EC50	7100.0	nM	10.1021/jm0492812
Homo sapiens	HEL	EC50	17000.0	nM	10.1021/jm0492812
Homo sapiens	HEL	EC50	20000.0	nM	10.1021/jm0492812
Homo sapiens	HEL	EC50	24000.0	nM	10.1021/jm049806q
Homo sapiens	HEL	EC50	27000.0	nM	10.1021/jm049806q
Homo sapiens	HEL	EC50	40000.0	nM	10.1016/s0960-894x(01)00471-1
Homo sapiens	HEL	EC50	41000.0	nM	10.1021/jm0108350
Homo sapiens	HEL	EC50	44000.0	nM	10.1016/s0960-894x(01)00471-1
Homo sapiens	HEL	EC50	63000.0	nM	10.1021/jm0108350
Homo sapiens	HEL	EC50	88000.0	nM	10.1016/j.bmcl.2003.09.033
Homo sapiens	HEL	EC50	111000.0	nM	10.1021/jm0492812
Homo sapiens	HEL	EC50	200000.0	nM	10.1021/jm049806q
Homo sapiens	HEL	EC50	400000.0	nM	10.1021/jm049806q
Homo sapiens	HEL	EC50	nan	None	10.1021/jm000118q
Homo sapiens	HEL	IC50	0.04	ug.mL-1	10.1021/jm00005a010
Homo sapiens	HEL	IC50	0.1	ug.mL-1	10.1021/jm00075a030
Homo sapiens	HEL	IC50	0.15	ug.mL-1	10.1021/jm00005a010
Homo sapiens	HEL	IC50	0.23	ug.mL-1	10.1016/S0960-894X(01)80538-2
Homo sapiens	HEL	IC50	0.32	ug.mL-1	10.1016/S0960-894X(01)80538-2
Homo sapiens	HEL	IC50	3.0	ug.mL-1	10.1021/jm00005a010
Homo sapiens	HEL	IC50	3.4	ug.mL-1	10.1021/jm9904194
Homo sapiens	HEL	IC50	4.0	ug.mL-1	10.1021/jm00075a030
Homo sapiens	HEL	IC50	5.0	ug.mL-1	10.1021/jm00005a010
Homo sapiens	HEL	IC50	5.0	ug.mL-1	10.1021/jm00075a030
Homo sapiens	HEL	IC50	5.4	ug.mL-1	10.1021/jm9904194
Homo sapiens	HEL	IC50	9.0	ug.mL-1	10.1016/S0960-894X(01)80538-2
Homo sapiens	HEL	IC50	15.0	ug.mL-1	10.1021/jm00005a010
Homo sapiens	HEL	IC50	20.0	ug.mL-1	10.1021/jm00005a010
Homo sapiens	HEL	IC50	22.0	ug.mL-1	10.1016/S0960-894X(01)80538-2
Homo sapiens	HEL	IC50	22.0	ug.mL-1	10.1021/jm00075a030
Homo sapiens	HEL	IC50	24.0	ug.mL-1	10.1016/S0960-894X(97)00149-2
Homo sapiens	HEL	IC50	26.0	ug.mL-1	10.1016/S0960-894X(97)00149-2
Homo sapiens	HEL	IC50	26.0	ug.mL-1	10.1021/jm00075a030
Homo sapiens	HEL	IC50	50.0	ug.mL-1	10.1016/S0960-894X(97)00365-X
Homo sapiens	HEL	IC50	160.0	nM	10.1021/jm991017z
Homo sapiens	HEL	IC50	200.0	ug.mL-1	10.1021/jm00075a030
Homo sapiens	HEL	IC50	780.0	nM	10.1021/jm991017z
Homo sapiens	HEL	IC50	12000.0	nM	10.1021/jm991017z
Homo sapiens	HEL	IC50	17000.0	nM	10.1021/jm991017z
Homo sapiens	HEL	IC50	50000.0	nM	10.1021/jm991017z
Homo sapiens	HEL	IC50	100000.0	nM	10.1021/jm991017z
Homo sapiens	HEL	IC50	200000.0	nM	10.1021/jm990346o
Homo sapiens	HEL	IC50	nan	nM	10.1021/jm991017z
Homo sapiens	HEL	IC50	nan	ug.mL-1	10.1016/s0960-894x(02)00535-8
Homo sapiens	HEL	IC50	nan	ug.mL-1	10.1021/jm981051y
Homo sapiens	HEL	IC50	nan	None	10.1021/jm9007856
Homo sapiens	HEL	MCC	40.0	ug.mL-1	10.1016/S0960-894X(01)80538-2
Homo sapiens	HEL	MCC	50.0	ug.mL-1	10.1016/s0960-894x(01)00838-1
Homo sapiens	HEL	MCC	50.0	ug.mL-1	10.1016/s0960-894x(02)00535-8
Homo sapiens	HEL	MCC	50.0	ug.mL-1	10.1021/jm980327z
Homo sapiens	HEL	MCC	100.0	ug.mL-1	10.1007/s00044-011-9776-0
Homo sapiens	HEL	MCC	100.0	ug.mL-1	10.1021/jm0707166
Homo sapiens	HEL	MCC	100.0	ug.mL-1	10.1021/jm9507901
Homo sapiens	HEL	MCC	250.0	ug.mL-1	10.1016/j.ejmech.2009.02.030
Homo sapiens	HEL	MCC	400.0	ug.mL-1	10.1016/j.bmc.2007.03.061
Homo sapiens	HEL	MCC	400.0	ug.mL-1	10.1016/j.bmc.2008.09.027
Homo sapiens	HEL	MCC	400.0	ug.mL-1	10.1016/j.ejmech.2007.04.010
Homo sapiens	HEL	MCC	400.0	ug.mL-1	10.1021/jm040869i
Homo sapiens	HEL	MCC	400.0	ug.mL-1	10.1021/jm050772b
Homo sapiens	HEL	MCC	400.0	ug.mL-1	10.1021/jm051023x
Homo sapiens	HEL	MCC	500.0	ug.mL-1	10.1007/s00044-012-0127-6
Homo sapiens	HEL	MCC	50000.0	nM	10.1016/j.ejmech.2010.12.017
Homo sapiens	HEL	MCC	88800.0	nM	10.1021/acsmedchemlett.8b00079
Homo sapiens	HEL	MCC	100000.0	nM	10.1016/j.ejmech.2012.08.042
Homo sapiens	HEL	MCC	100000.0	nM	10.1016/j.ejmech.2013.09.047
Homo sapiens	HEL	MCC	100000.0	nM	10.1021/jm9007856
Homo sapiens	HEL	MCC	150000.0	nM	10.1021/jm000118q
Homo sapiens	HEL	MCC	200000.0	nM	10.1016/s0960-894x(00)00672-7
Homo sapiens	HEL	MCC	200000.0	nM	10.1016/s0960-894x(01)00471-1
Homo sapiens	HEL	MCC	200000.0	nM	10.1021/jm070357e
Homo sapiens	HEL	MCC	200000.0	nM	10.1021/jm8014662
Homo sapiens	HEL	MCC	200000.0	nM	10.1021/jm990346o
Homo sapiens	HEL	MCC	220000.0	nM	10.1021/jm070210n
Homo sapiens	HEL	MCC	222000.0	nM	10.1016/j.bmc.2011.04.016
Homo sapiens	HEL	MCC	222000.0	nM	10.1021/jm050867d
Homo sapiens	HEL	MCC	250000.0	nM	10.1007/s00044-012-0184-x
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.bmc.2008.08.041
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.bmc.2011.05.037
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.bmc.2015.04.079
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.bmc.2018.05.034
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.bmc.2019.02.005
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.bmcl.2008.06.069
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.bmcl.2012.09.079
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.bmcl.2018.09.019
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.ejmech.2012.03.007
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.ejmech.2013.02.039
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.ejmech.2013.05.046
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.ejmech.2013.06.036
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.ejmech.2015.06.024
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.ejmech.2016.10.002
Homo sapiens	HEL	MCC	250000.0	nM	10.1016/j.ejmech.2022.114618
Homo sapiens	HEL	MCC	250000.0	nM	10.1021/acs.jmedchem.7b01009
Homo sapiens	HEL	MCC	300000.0	nM	10.1016/j.ejmech.2012.04.001
Homo sapiens	HEL	MCC	440000.0	nM	10.1016/j.bmc.2014.02.056
Homo sapiens	HEL	MCC	440000.0	nM	10.1016/j.bmc.2015.09.033
Homo sapiens	HEL	MCC	440000.0	nM	10.1016/j.bmc.2017.06.046
Homo sapiens	HEL	MCC	440000.0	nM	10.1016/j.ejmech.2016.10.002
Homo sapiens	HEL	MCC	440000.0	nM	10.1016/j.ejmech.2018.01.086
Homo sapiens	HEL	MCC	440000.0	nM	10.1016/j.ejmech.2020.112884
Homo sapiens	HEL	MCC	440000.0	nM	10.1021/acsmedchemlett.0c00485
Homo sapiens	HEL	MCC	444000.0	nM	10.1016/j.bmc.2011.06.045
Homo sapiens	HEL	MCC	444000.0	nM	10.1016/j.ejmech.2012.07.027
Homo sapiens	HEL	MCC	444000.0	nM	10.1016/j.ejmech.2017.12.018
Homo sapiens	HEL	MCC	444000.0	nM	10.1016/j.ejmech.2018.03.008
Homo sapiens	HEL	MCC	444000.0	nM	10.1021/acs.jmedchem.7b00416
Homo sapiens	HEL	MCC	444000.0	nM	10.1021/acsmedchemlett.0c00090
Homo sapiens	HEL	MCC	444000.0	nM	10.1021/jm901828c
Homo sapiens	HEL	MCC	444030.0	nM	10.1021/acs.jmedchem.2c00667
Homo sapiens	HEL	MCC	1200000.0	nM	10.1021/jm0492812
Homo sapiens	HEL	MCC	1576000.0	nM	10.1021/jm901828c
Homo sapiens	HEL	MCC	1778000.0	nM	10.1016/j.bmcl.2009.12.102
Homo sapiens	HEL	MCC	1778000.0	nM	10.1016/j.ejmech.2009.03.005
Homo sapiens	HEL	MCC	1778000.0	nM	10.1021/jm0614329
Homo sapiens	HEL	MCC	1778000.0	nM	10.1021/jm070324z
Homo sapiens	HEL	MIC	0.0007	ug.mL-1	10.1021/jm00090a007
Homo sapiens	HEL	MIC	0.001	ug.mL-1	10.1021/jm00090a007
Homo sapiens	HEL	MIC	0.1	ug.mL-1	10.1021/jm960770e
Homo sapiens	HEL	MIC	0.2	ug.mL-1	10.1021/jm00112a010
Homo sapiens	HEL	MIC	0.3	ug.mL-1	10.1021/jm00112a010
Homo sapiens	HEL	MIC	1.1	ug.mL-1	10.1016/s0960-894x(01)00838-1
Homo sapiens	HEL	MIC	4.0	ug.mL-1	10.1021/jm00035a010
Homo sapiens	HEL	MIC	5.0	ug.mL-1	10.1021/jm00112a010
Homo sapiens	HEL	MIC	5.0	ug.mL-1	10.1021/jm960770e
Homo sapiens	HEL	MIC	10.0	ug.mL-1	10.1021/jm00090a007
Homo sapiens	HEL	MIC	10.0	ug.mL-1	10.1021/jm00112a010
Homo sapiens	HEL	MIC	15.0	ug.mL-1	10.1021/jm00112a010
Homo sapiens	HEL	MIC	35.0	ug.mL-1	10.1021/jm00035a010
Homo sapiens	HEL	MIC	50.0	ug.mL-1	10.1021/jm00035a010
Homo sapiens	HEL	MIC	80.0	ug.mL-1	10.1021/jm00035a010
Homo sapiens	HEL	MIC	200.0	ug.mL-1	10.1021/jm00035a010
Homo sapiens	HEL	MIC	200.0	ug.mL-1	10.1021/jm00045a025
Homo sapiens	HEL	MIC	200.0	ug.mL-1	10.1021/jm00066a013
Homo sapiens	HEL	MIC	200.0	ug.mL-1	10.1021/jm00112a010
Homo sapiens	HEL	MIC	200.0	ug.mL-1	10.1021/jm960770e
Homo sapiens	HEL	MIC	150000.0	nM	10.1021/jm0108350
Homo sapiens	HEL	MTC	1700.0	uM	10.1021/jm0504306
Homo sapiens	HeLa	CC100	600.0	ug ml-1	10.1016/j.ejmech.2009.01.014
Homo sapiens	HeLa	CC50	200.0	ug.mL-1	10.1016/S0960-894X(97)00149-2
Homo sapiens	HeLa	CC50	400000.0	nM	10.1016/j.bmcl.2004.03.029
Homo sapiens	HeLa	CC50	400000.0	nM	10.1016/j.bmcl.2005.05.071
Homo sapiens	HeLa	CC50	541000.0	nM	10.1016/j.ejmech.2012.03.007
Homo sapiens	HeLa	IC50	0.1	ug.mL-1	10.1021/jm00023a004
Homo sapiens	HeLa	IC50	0.23	ug.mL-1	10.1021/jm00023a004
Homo sapiens	HeLa	IC50	20.0	ug.mL-1	10.1021/jm00023a004
Homo sapiens	HeLa	IC50	110.0	nM	10.1021/jm0004446
Homo sapiens	HeLa	IC50	190.0	nM	10.1021/jm0004446
Homo sapiens	HeLa	IC50	250.0	ug.mL-1	10.1021/jm00023a004
Homo sapiens	HeLa	IC50	1900.0	nM	10.1021/jm00010a027
Homo sapiens	HeLa	IC50	8710.0	nM	10.1021/jm0004446
Homo sapiens	HeLa	IC50	26430.0	nM	10.1021/jm0004446
Homo sapiens	HeLa	IC50	200000.0	nM	10.1021/jm00010a027
Homo sapiens	HeLa	IC50	253640.0	nM	10.1021/jm0004446
Homo sapiens	HeLa	IC50	nan	ug.mL-1	10.1016/S0960-894X(97)00365-X
Homo sapiens	HeLa	MCC	200000.0	nM	10.1016/j.bmcl.2004.03.029
Homo sapiens	HeLa	MCC	nan	None	10.1021/jm050772b
Homo sapiens	HeLa	MIC	12.3	ug.mL-1	10.1016/s0960-894x(01)00838-1
Homo sapiens	HeLa	Tox50	10000.0	uM	10.1021/jm00379a010
Homo sapiens	Hemoglobin beta chain	Potency	12589.3	nM	None
Homo sapiens	HEp-2	MTC	330.0	ug ml-1	10.1021/jm00149a024
Homo sapiens	HepG2	IC50	nan	nM	10.1016/s0960-894x(00)00418-2
Homo sapiens	HepG2	Potency	891.3	nM	None
Homo sapiens	HERG	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	HERG	IC50	nan	None	None
Homo sapiens	HERG	Ki	nan	None	None
Homo sapiens	HFF	CC50	100000.0	nM	10.1016/j.bmcl.2007.03.102
Homo sapiens	HFF	CC50	100000.0	nM	10.1016/j.bmcl.2008.06.060
Homo sapiens	HFF	CC50	100000.0	nM	10.1016/j.bmcl.2010.03.115
Homo sapiens	HFF	CC50	100000.0	nM	10.1016/j.ejmech.2011.02.014
Homo sapiens	HFF	CC50	100000.0	nM	10.1021/jm050162b
Homo sapiens	HFF	CC50	150000.0	nM	10.1021/acs.jmedchem.2c00667
Homo sapiens	HFF	CC50	300000.0	nM	10.1016/j.bmc.2009.04.020
Homo sapiens	HFF	CC50	300000.0	nM	10.1016/j.bmc.2012.04.049
Homo sapiens	HFF	CC50	300000.0	nM	10.1021/acs.jmedchem.6b00659
Homo sapiens	HFF	CC50	444000.0	nM	10.1021/jm040093l
Homo sapiens	HFF	CC50	444000.0	nM	10.1021/jm040149b
Homo sapiens	HFF	CC50	444000.0	nM	10.1128/aac.00417-09
Homo sapiens	HFF	CC50	nan	None	10.1016/j.ejmech.2011.02.014
Homo sapiens	HFF	CC50	nan	None	10.1021/acs.jmedchem.2c00667
Homo sapiens	HFF	CC50	nan	None	10.1039/d1md00086a
Homo sapiens	HFF	EC50	1100.0	nM	10.1021/jm030241s
Homo sapiens	HFF	EC50	1680.0	nM	10.1021/jm030241s
Homo sapiens	HFF	IC50	2.7	ug.mL-1	10.1021/jm9705869
Homo sapiens	HFF	IC50	8100.0	nM	10.1021/jm050162b
Homo sapiens	HFF	IC50	20000.0	nM	10.1021/jm050162b
Homo sapiens	HFF	IC50	100000.0	nM	10.1021/jm00119a006
Homo sapiens	HFF	IC50	100000.0	nM	10.1021/jm00169a027
Homo sapiens	HFF	IC50	100000.0	nM	10.1021/jm00174a011
Homo sapiens	HFF	IC50	100000.0	nM	10.1021/jm00403a005
Homo sapiens	HFF	IC50	100000.0	nM	10.1021/jm950835y
Homo sapiens	HFF	IC50	444000.0	nM	10.1128/aac.00417-09
Homo sapiens	HFF	MTC	320.0	None	10.1021/jm9705869
Homo sapiens	HFF	SI	83.0	None	10.1021/jm9705869
Homo sapiens	Histamine H1 receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Histamine H1 receptor	IC50	nan	None	None
Homo sapiens	Histamine H1 receptor	Ki	nan	None	None
Homo sapiens	Histamine H2 receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Histamine H2 receptor	IC50	nan	None	None
Homo sapiens	Histamine H2 receptor	Ki	nan	None	None
Homo sapiens	Histamine H3 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Histone deacetylase 6	Inhibition	-24.99	%	10.6019/CHEMBL4808148
Homo sapiens	Histone deacetylase 6	Inhibition	-1.46	%	10.6019/CHEMBL4808148
Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Potency	25.1	nM	None
Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Potency	39810.7	nM	None
Homo sapiens	HMG-CoA reductase	IC50	nan	None	None
Homo sapiens	HMG-CoA reductase	Ki	nan	None	None
Homo sapiens	Homo sapiens	% absorbed	20.0	%	10.1021/jm001020e
Homo sapiens	Homo sapiens	Activity	0.23	%	10.1016/j.ejmech.2009.11.034
Homo sapiens	Homo sapiens	AUC	8332.77	ng.hr.mL-1	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	AUC	30853.77	ng.hr.mL-1	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	AUC	35808.39	ng.hr.mL-1	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	AUC	129946.17	ng.hr.mL-1	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	CC50	nan	nM	10.1021/jm030241s
Homo sapiens	Homo sapiens	CL	0.2	L/hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	CL	0.5	L/hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	CL	1.1	mL.min-1.kg-1	10.1021/jm901371v
Homo sapiens	Homo sapiens	CL	1.2	L/hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	CL	4.7	mL.min-1.kg-1	10.1021/jm900403j
Homo sapiens	Homo sapiens	CL	4.7	mL.min-1.kg-1	10.1021/jm901371v
Homo sapiens	Homo sapiens	CL/F	145.0	ml/min	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	CL/F	759.0	ml/min	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	CL_renal	3.57	mL.min-1.kg-1	10.1021/jm900403j
Homo sapiens	Homo sapiens	CL_renal	3.6	L/hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	CL_renal	3.6	mL.min-1.kg-1	10.1021/jm901371v
Homo sapiens	Homo sapiens	CL_renal	3.8	L/hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	CL_renal	3.9	L/hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	CL_renal	8.4	L/hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	Cmax	7800.0	nM	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Cmax	16000.0	nM	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Cmax	42000.0	nM	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Cmax	82000.0	nM	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Cytotoxicity	0.0	None	10.1021/jm00394a017
Homo sapiens	Homo sapiens	DILI_Concern	nan	None	10.1016/j.drudis.2016.02.015
Homo sapiens	Homo sapiens	DILI_severity_class	5.0	None	10.1016/j.drudis.2016.02.015
Homo sapiens	Homo sapiens	Drug uptake	6.25	uM	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Drug uptake	13.3	uM	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Drug uptake	23.0	uM	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Drug uptake	48.0	uM	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	EC50	40.0	nM	10.1021/jm00069a004
Homo sapiens	Homo sapiens	EC50	90.0	nM	10.1021/jm00069a004
Homo sapiens	Homo sapiens	EC50	1100.0	nM	10.1021/jm030241s
Homo sapiens	Homo sapiens	EC50	1680.0	nM	10.1021/jm030241s
Homo sapiens	Homo sapiens	EC50	7100.0	nM	10.1021/jm00069a004
Homo sapiens	Homo sapiens	EC50	10210.0	nM	10.1021/jm030241s
Homo sapiens	Homo sapiens	EC50	nan	nM	10.1021/jm00069a004
Homo sapiens	Homo sapiens	F	10.0	%	10.1016/j.ejmech.2013.10.001
Homo sapiens	Homo sapiens	F	21.0	%	10.1021/jm901421c
Homo sapiens	Homo sapiens	F	21.0	%	10.1021/jm901846t
Homo sapiens	Homo sapiens	F	48.0	%	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	F	54.0	%	10.1128/aac.00116-07
Homo sapiens	Homo sapiens	F	60.0	%	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	Fa	0.23	None	10.1021/jm901371v
Homo sapiens	Homo sapiens	F_fraction	0.23	None	10.1021/jm901371v
Homo sapiens	Homo sapiens	Fg	1.05	None	10.1021/jm901371v
Homo sapiens	Homo sapiens	Fh	0.95	None	10.1021/jm901371v
Homo sapiens	Homo sapiens	IC50	100000.0	nM	10.1021/jm00127a003
Homo sapiens	Homo sapiens	IC50	440000.0	nM	10.1021/jm00069a004
Homo sapiens	Homo sapiens	IC50	nan	ug.mL-1	10.1016/s0960-894x(01)00589-3
Homo sapiens	Homo sapiens	ID50	165.0	ug ml-1	10.1021/jm00167a002
Homo sapiens	Homo sapiens	Ratio	0.19	None	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Ratio	0.2	None	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Reduction	32.0	%	10.1021/jm00394a017
Homo sapiens	Homo sapiens	Reduction	35.0	%	10.1021/jm00394a017
Homo sapiens	Homo sapiens	Reduction	41.0	%	10.1021/jm00394a017
Homo sapiens	Homo sapiens	Reduction	79.0	%	10.1021/jm00394a017
Homo sapiens	Homo sapiens	Reduction	94.0	%	10.1021/jm00394a017
Homo sapiens	Homo sapiens	Reduction	100.0	%	10.1021/jm00394a017
Homo sapiens	Homo sapiens	T1/2	1.4	hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	T1/2	1.5	hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	T1/2	1.7	hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	T1/2	1.9	hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	T1/2	2.1	hr	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	Tmax	2.0	hr	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Tmax	2.1	hr	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Tmax	2.3	hr	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Tmax	5.3	hr	10.1128/aac.00729-09
Homo sapiens	Homo sapiens	Vd	0.4	L.kg-1	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	Vd	1.2	L.kg-1	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	Vd	1.3	L.kg-1	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	Vd	3.0	L.kg-1	10.1128/aac.01138-08
Homo sapiens	Homo sapiens	Vdss	0.69	L.kg-1	10.1016/j.ejmech.2009.06.004
Homo sapiens	Homo sapiens	Vdss	0.71	L.kg-1	10.1021/jm901371v
Homo sapiens	Interleukin-8 receptor A	IC50	nan	None	None
Homo sapiens	Interleukin-8 receptor A	Ki	nan	None	None
Homo sapiens	Interleukin-8 receptor B	IC50	nan	None	None
Homo sapiens	Interleukin-8 receptor B	Ki	nan	None	None
Homo sapiens	Kappa opioid receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Kappa opioid receptor	IC50	nan	None	None
Homo sapiens	Kappa opioid receptor	Ki	nan	None	None
Homo sapiens	KB	CC50	100000.0	nM	10.1021/jm0607404
Homo sapiens	KB	IC50	100000.0	nM	10.1021/jm00044a015
Homo sapiens	KB	IC50	100000.0	nM	10.1021/jm00081a014
Homo sapiens	KB	IC50	100000.0	nM	10.1021/jm950835y
Homo sapiens	KB	IC50	nan	None	10.1021/jm2001426
Homo sapiens	Leukocyte common antigen	IC50	nan	None	None
Homo sapiens	Leukocyte common antigen	Ki	nan	None	None
Homo sapiens	Leukocyte elastase	IC50	nan	None	None
Homo sapiens	Leukocyte elastase	Ki	nan	None	None
Homo sapiens	MAP kinase ERK1	IC50	nan	None	None
Homo sapiens	MAP kinase ERK1	Ki	nan	None	None
Homo sapiens	MAP kinase ERK2	IC50	nan	None	None
Homo sapiens	MAP kinase ERK2	Ki	nan	None	None
Homo sapiens	MAP kinase p38 alpha	IC50	nan	None	None
Homo sapiens	MAP kinase p38 alpha	Ki	nan	None	None
Homo sapiens	Matrix metalloproteinase-1	IC50	nan	None	None
Homo sapiens	Matrix metalloproteinase-1	Ki	nan	None	None
Homo sapiens	Matrix metalloproteinase 9	IC50	nan	None	None
Homo sapiens	Matrix metalloproteinase 9	Ki	nan	None	None
Homo sapiens	MCF-10A	Activity	nan	None	10.1007/s00044-007-9065-0
Homo sapiens	MCF-12A	Activity	nan	None	10.1007/s00044-007-9065-0
Homo sapiens	MCF7	Activity	nan	None	10.1007/s00044-007-9065-0
Homo sapiens	MDA-MB-231	Activity	nan	None	10.1007/s00044-007-9065-0
Homo sapiens	Melanocortin receptor 3	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Melanocortin receptor 3	IC50	nan	None	None
Homo sapiens	Melanocortin receptor 3	Ki	nan	None	None
Homo sapiens	Melanocortin receptor 4	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Melanocortin receptor 4	IC50	nan	None	None
Homo sapiens	Melanocortin receptor 4	Ki	nan	None	None
Homo sapiens	Melanocortin receptor 5	IC50	nan	None	None
Homo sapiens	Melanocortin receptor 5	Ki	nan	None	None
Homo sapiens	MOLT-4F	ID50	100.0	ug ml-1	10.1021/jm00171a009
Homo sapiens	Monoamine oxidase A	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Monoamine oxidase A	IC50	nan	None	None
Homo sapiens	Monoamine oxidase A	Ki	nan	None	None
Homo sapiens	Mothers against decapentaplegic homolog 3	Potency	3981.1	nM	None
Homo sapiens	Motilin receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	MRC5	CC50	100000.0	nM	10.1016/0960-894X(95)00208-B
Homo sapiens	MRC5	CD50	355.0	uM	10.1021/jm00062a006
Homo sapiens	MRC5	EC50	5000.0	nM	10.1016/s0960-894x(00)00061-5
Homo sapiens	MRC5	EC50	18000.0	nM	10.1016/0960-894X(95)00208-B
Homo sapiens	MRC5	EC50	50000.0	nM	10.1016/s0960-894x(00)00061-5
Homo sapiens	MRC5	IC50	0.25	ug.mL-1	10.1021/jm9904194
Homo sapiens	MRC5	IC50	0.29	ug.mL-1	10.1021/jm9904194
Homo sapiens	MRC5	IC50	1.3	ug.mL-1	10.1021/jm9904194
Homo sapiens	MRC5	IC50	2500.0	nM	10.1021/jm00163a031
Homo sapiens	MRC5	IC50	20000.0	nM	10.1021/jm00163a031
Homo sapiens	MRC5	IC90	300.0	nM	10.1021/jm00392a020
Homo sapiens	MRC5	IC90	700.0	nM	10.1021/jm00392a020
Homo sapiens	MRC5	IC90	900.0	nM	10.1021/jm00392a020
Homo sapiens	MRC5	IC90	1200.0	nM	10.1021/jm00392a020
Homo sapiens	MRC5	IC90	1400.0	nM	10.1021/jm00392a020
Homo sapiens	MRC5	IC90	4800.0	nM	10.1021/jm00392a020
Homo sapiens	MRC5	ID50	38.4	ug ml-1	10.1021/jm00111a052
Homo sapiens	MRC5	MIC50	1300.0	nM	10.1021/jm00113a016
Homo sapiens	MRC5	MIC50	14500.0	nM	10.1021/jm00113a016
Homo sapiens	MRC5	MIC50	100000.0	nM	10.1021/jm00113a016
Homo sapiens	MT2	IC50	nan	nM	10.1016/s0960-894x(00)00418-2
Homo sapiens	MT2	ID50	nan	None	10.1021/jm034265a
Homo sapiens	MT4	Activity	nan	None	10.1016/s0960-894x(02)00394-3
Homo sapiens	MT4	CC50	11.4	ug.mL-1	10.1016/s0960-894x(02)00394-3
Homo sapiens	MT4	CC50	76.6	ug.mL-1	10.1016/s0960-894x(02)00394-3
Homo sapiens	MT4	CC50	100000.0	nM	10.1016/j.bmc.2009.05.020
Homo sapiens	MT4	CC50	100000.0	nM	10.1016/j.bmc.2010.02.037
Homo sapiens	MT4	CC50	100000.0	nM	10.1016/j.bmc.2014.06.043
Homo sapiens	MT4	CC50	100000.0	nM	10.1016/j.bmc.2015.09.035
Homo sapiens	MT4	CC50	250000.0	nM	10.1016/j.ejmech.2013.09.047
Homo sapiens	MT4	CC50	250000.0	nM	10.1021/jm9007856
Homo sapiens	MT4	EC50	nan	ug.mL-1	10.1016/0960-894X(95)00395-A
Homo sapiens	MT4	IC50	100.0	ug.mL-1	10.1021/jm00075a030
Homo sapiens	MT4	IC50	250000.0	nM	10.1021/jm9007856
Homo sapiens	Multidrug resistance-associated protein 4	IC50	133000.0	nM	10.1093/toxsci/kft176
Homo sapiens	Mu opioid receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Mu opioid receptor	IC50	nan	None	None
Homo sapiens	Mu opioid receptor	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M1	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Muscarinic acetylcholine receptor M1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Muscarinic acetylcholine receptor M1	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M1	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M2	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Muscarinic acetylcholine receptor M2	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Muscarinic acetylcholine receptor M2	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M2	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M3	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M3	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M4	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M4	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M5	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Muscarinic acetylcholine receptor M5	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M5	Ki	nan	None	None
Homo sapiens	NC-37	CC50	100.0	ug.mL-1	10.1016/S0960-894X(01)80146-3
Homo sapiens	NC-37	EC50	0.17	ug.mL-1	10.1016/S0960-894X(01)80146-3
Homo sapiens	Neoplastic cell line	IC50	100000.0	nM	10.1021/jm00169a028
Homo sapiens	Neurokinin 1 receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Neurokinin 1 receptor	IC50	nan	None	None
Homo sapiens	Neurokinin 1 receptor	Ki	nan	None	None
Homo sapiens	Neurokinin 2 receptor	IC50	nan	None	None
Homo sapiens	Neurokinin 2 receptor	Ki	nan	None	None
Homo sapiens	Neuronal acetylcholine receptor protein alpha-4 subunit	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Neuropeptide Y receptor type 1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Neuropeptide Y receptor type 1	IC50	nan	None	None
Homo sapiens	Neuropeptide Y receptor type 1	Ki	nan	None	None
Homo sapiens	Neuropeptide Y receptor type 2	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Neuropeptide Y receptor type 2	IC50	nan	None	None
Homo sapiens	Neuropeptide Y receptor type 2	Ki	nan	None	None
Homo sapiens	Neurotensin receptor 1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Norepinephrine transporter	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Norepinephrine transporter	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Norepinephrine transporter	IC50	nan	None	None
Homo sapiens	Norepinephrine transporter	Ki	nan	None	None
Homo sapiens	P3HR-1	CC50	392000.0	nM	10.1021/jm0209275
Homo sapiens	Phosphodiesterase 3A	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Phosphodiesterase 4A	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Phosphodiesterase 4D	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Phosphodiesterase 5A	IC50	nan	None	None
Homo sapiens	Phosphodiesterase 5A	Ki	nan	None	None
Homo sapiens	Plasma	fCmax	18.87	uM	10.1124/dmd.111.040758
Homo sapiens	Platelet activating factor receptor	IC50	nan	None	None
Homo sapiens	Platelet activating factor receptor	Ki	nan	None	None
Homo sapiens	POU domain, class 2, transcription factor 2	Drug transport	nan	None	10.1124/dmd.111.042036
Homo sapiens	POU domain, class 2, transcription factor 2	Jmax	561.0	pmol/min	10.1124/dmd.111.042036
Homo sapiens	POU domain, class 2, transcription factor 2	Km	94000.0	nM	10.1124/dmd.111.042036
Homo sapiens	POU domain, class 2, transcription factor 2	Ratio	6.0	uL/min	10.1124/dmd.111.042036
Homo sapiens	Prelamin-A/C	Potency	0.9	nM	None
Homo sapiens	Progesterone receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Protein kinase C alpha	IC50	nan	None	None
Homo sapiens	Protein kinase C alpha	Ki	nan	None	None
Homo sapiens	Purine nucleoside phosphorylase	Ki	91000.0	nM	10.1039/C8MD00372F
Homo sapiens	Purine nucleoside phosphorylase	Ki	180000.0	nM	10.1021/jm00060a010
Homo sapiens	Raji	EC50	2900.0	nM	10.1021/jm00069a004
Homo sapiens	Raji	ED50	3.8	ug ml-1	10.1021/jm00167a002
Homo sapiens	Raji	ID50	100.0	ug ml-1	10.1021/jm00167a002
Homo sapiens	Raji	ID50	100.0	ug ml-1	10.1021/jm00171a009
Homo sapiens	RD	CC50	25000.0	nM	10.1016/j.bmcl.2011.02.037
Homo sapiens	Receptor protein-tyrosine kinase erbB-2	IC50	nan	None	None
Homo sapiens	Receptor protein-tyrosine kinase erbB-2	Ki	nan	None	None
Homo sapiens	Runt-related transcription factor 1/Core-binding factor subunit beta	Potency	31622.8	nM	None
Homo sapiens	Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform	IC50	nan	None	None
Homo sapiens	Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform	Ki	nan	None	None
Homo sapiens	Serotonin 1a (5-HT1a) receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 1a (5-HT1a) receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 2a (5-HT2a) receptor	AC50	3371.9	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 2a (5-HT2a) receptor	IC50	nan	None	None
Homo sapiens	Serotonin 2a (5-HT2a) receptor	Ki	nan	None	None
Homo sapiens	Serotonin 2b (5-HT2b) receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 2b (5-HT2b) receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 2b (5-HT2b) receptor	IC50	nan	None	None
Homo sapiens	Serotonin 2b (5-HT2b) receptor	Ki	nan	None	None
Homo sapiens	Serotonin 2c (5-HT2c) receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 2c (5-HT2c) receptor	IC50	nan	None	None
Homo sapiens	Serotonin 2c (5-HT2c) receptor	Ki	nan	None	None
Homo sapiens	Serotonin 3a (5-HT3a) receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 6 (5-HT6) receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 6 (5-HT6) receptor	IC50	nan	None	None
Homo sapiens	Serotonin 6 (5-HT6) receptor	Ki	nan	None	None
Homo sapiens	Serotonin 7 (5-HT7) receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin transporter	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin transporter	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin transporter	IC50	nan	None	None
Homo sapiens	Serotonin transporter	Ki	nan	None	None
Homo sapiens	Sigma opioid receptor	IC50	nan	None	None
Homo sapiens	Sigma opioid receptor	Ki	nan	None	None
Homo sapiens	Sodium channel protein type V alpha subunit	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Solute carrier family 22 member 1	Activity	88.4	%	10.1124/jpet.300.3.918
Homo sapiens	Solute carrier family 22 member 1	Inhibition	-3.9	%	10.1021/jm8003152
Homo sapiens	Solute carrier family 22 member 1	Km	151200.0	nM	10.1124/jpet.300.3.918
Homo sapiens	Solute carrier family 22 member 6	Activity	67.0	%	10.1124/jpet.300.3.918
Homo sapiens	Solute carrier family 22 member 6	Activity	nan	None	10.1038/nrd3028
Homo sapiens	Solute carrier family 22 member 6	FC	1.7	None	10.1124/dmd.111.042036
Homo sapiens	Solute carrier family 22 member 6	Jmax	434.0	pmol/min	10.1124/dmd.111.042036
Homo sapiens	Solute carrier family 22 member 6	Km	342300.0	nM	10.1124/jpet.300.3.918
Homo sapiens	Solute carrier family 22 member 6	Km	839000.0	nM	10.1124/dmd.111.042036
Homo sapiens	Solute carrier family 22 member 6	Ratio	0.5	uL/min	10.1124/dmd.111.042036
Homo sapiens	Solute carrier family 22 member 7	FC	10.0	None	10.1124/dmd.111.042036
Homo sapiens	Solute carrier family 22 member 8	Activity	64.3	%	10.1124/jpet.300.3.918
Homo sapiens	Solute carrier family 22 member 8	Activity	nan	None	10.1124/mol.59.5.1277
Homo sapiens	Solute carrier family 22 member 8	FC	1.7	None	10.1124/dmd.111.042036
Homo sapiens	Solute carrier family 22 member 8	Jmax	797.0	pmol/min	10.1124/dmd.111.042036
Homo sapiens	Solute carrier family 22 member 8	Km	772000.0	nM	10.1124/dmd.111.042036
Homo sapiens	Solute carrier family 22 member 8	Ratio	1.0	uL/min	10.1124/dmd.111.042036
Homo sapiens	Solute carrier organic anion transporter family member 1B1	Inhibition	2.3	%	10.1021/jm300212s
Homo sapiens	Solute carrier organic anion transporter family member 1B1	Inhibition	103.39	%	10.1124/mol.112.084152
Homo sapiens	Solute carrier organic anion transporter family member 1B3	Inhibition	-2.0	%	10.1021/jm300212s
Homo sapiens	Solute carrier organic anion transporter family member 1B3	Inhibition	105.48	%	10.1124/mol.112.084152
Homo sapiens	Solute carrier organic anion transporter family member 2B1	Inhibition	-15.2	%	10.1021/jm300212s
Homo sapiens	Thrombin	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Thromboxane A2 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Thromboxane-A synthase	IC50	nan	None	None
Homo sapiens	Thromboxane-A synthase	Ki	nan	None	None
Homo sapiens	Thymidine kinase, cytosolic	Activity	23.0	%	10.1021/jm00158a011
Homo sapiens	Thymidine kinase, cytosolic	Inhibition	69.0	%	10.1021/jm00146a002
Homo sapiens	Thymidine kinase, cytosolic	k cat	0.1	s-1	10.1021/jm030241s
Homo sapiens	Thymidine kinase, cytosolic	Kinase activity	13.0	pM min-1*ml-1	10.1021/jm00088a015
Homo sapiens	Thymidine kinase, cytosolic	Km	1500.0	nM	10.1021/jm010216r
Homo sapiens	Thymidine kinase, cytosolic	Km	2200.0	nM	10.1021/jm010216r
Homo sapiens	Thymidine kinase, cytosolic	Relative substrate velocity	36.0	%	10.1021/jm00146a002
Homo sapiens	Thymidine kinase, cytosolic	Relative Vmax	3.0	None	10.1021/jm010216r
Homo sapiens	Thymidine kinase, cytosolic	Relative Vmax	39.2	None	10.1021/jm010216r
Homo sapiens	Thyroid stimulating hormone receptor	Potency	15848.9	nM	None
Homo sapiens	Type-1 angiotensin II receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Tyrosine-protein kinase FYN	IC50	nan	None	None
Homo sapiens	Tyrosine-protein kinase FYN	Ki	nan	None	None
Homo sapiens	Tyrosine-protein kinase LCK	IC50	nan	None	None
Homo sapiens	Tyrosine-protein kinase LCK	Ki	nan	None	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	259.3	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	446.7	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	452.8	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	508.1	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	1158.2	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	1299.5	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	2238.7	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	5173.5	nM	None
Homo sapiens	Ubiquitin carboxyl-terminal hydrolase 2	Potency	12589.3	nM	None
Homo sapiens	Vascular endothelial growth factor receptor 1	IC50	nan	None	None
Homo sapiens	Vascular endothelial growth factor receptor 1	Ki	nan	None	None
Homo sapiens	Vascular endothelial growth factor receptor 2	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Vasoactive intestinal polypeptide receptor 1	IC50	nan	None	None
Homo sapiens	Vasoactive intestinal polypeptide receptor 1	Ki	nan	None	None
Homo sapiens	Vasopressin V1a receptor	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Vasopressin V1a receptor	IC50	nan	None	None
Homo sapiens	Vasopressin V1a receptor	Ki	nan	None	None
Homo sapiens	Vasopressin V2 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	WI-38	ID50	0.2	uM	10.1021/jm00088a015
Homo sapiens	WI-38	ID50	0.8	uM	10.1021/jm00088a015
Homo sapiens	WI-38	ID50	2.0	uM	10.1021/jm00088a015
Homo sapiens	WI-38	ID50	4.0	uM	10.1021/jm00088a015
Homo sapiens	WI-38	ID50	40.0	uM	10.1021/jm00088a015
Homo sapiens	WI-38	ID50	110.0	uM	10.1021/jm00088a015
Homo sapiens	WI-38	ID50	220.0	uM	10.1021/jm00088a015
Homo sapiens	WI-38	ID50	750.0	uM	10.1021/jm00088a015
Homo sapiens	WI-38	ID50	800.0	uM	10.1021/jm00061a013
Homo sapiens	WISH	Activity	3414.0	umol/L	10.1016/j.bmcl.2014.11.065
Human adenovirus 2	Human adenovirus 2	EC50	5800.0	nM	10.1016/j.ejmech.2019.111739
Human adenovirus 2	Human adenovirus 2	EC50	nan	None	10.1016/j.ejmech.2022.114618
Human adenovirus 2	Human adenovirus 2	Inhibition	nan	%	10.1016/j.bmc.2013.07.031
Human adenovirus 5	Human adenovirus 5	Activity	nan	None	10.1016/j.ejmech.2021.113738
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	0.012	ug ml-1	10.1007/s00044-010-9338-x
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	0.1	%	10.1016/j.bmc.2018.03.018
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	0.44	%	10.1016/j.bmcl.2017.09.026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	0.76	%	10.1016/j.bmcl.2017.09.026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	1.13	%	10.1016/j.bmcl.2017.09.026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	1.36	%	10.1016/j.bmcl.2017.09.026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	1.6	ug ml-1	10.1007/s00044-010-9338-x
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	2.0	None	10.1021/np50107a013
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	3.0	None	10.1021/np50107a013
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	3.25	None	10.1021/np50107a013
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	6.0	ug ml-1	10.1016/j.ejmech.2009.01.014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	6.0	ug ml-1	10.1016/j.ejmech.2009.10.010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	6.22	%	10.1016/j.bmcl.2017.09.026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	7.92	%	10.1016/j.bmcl.2017.09.026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	10.0	None	10.1016/j.ejmech.2009.01.014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	12.0	%	10.1016/j.ejmech.2009.02.012
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	28.0	%	10.1016/j.ejmech.2009.02.012
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	33.3	PFU/ml	10.1021/acsmedchemlett.5b00318
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	89.6	%	10.1016/j.bmcl.2017.09.026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	92.6	%	10.1016/j.bmcl.2017.09.026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	100.0	%	10.1007/s00044-011-9960-2
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	100.0	%	10.1016/j.bmc.2019.02.044
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	nan	None	10.1016/j.bmc.2019.02.044
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	nan	None	10.1016/j.bmc.2020.115304
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	nan	None	10.1016/j.bmcl.2011.01.098
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	nan	None	10.1016/j.bmcl.2012.05.079
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	nan	None	10.1016/j.bmcl.2020.127559
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	nan	None	10.1016/j.ejmech.2021.113738
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	nan	None	10.1021/acsmedchemlett.5b00318
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Activity	nan	None	10.1021/np50070a001
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Average lesion score	1.45	None	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Average lesion score	2.95	None	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Average lesion score	3.75	None	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Average survival	6.5	day	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Average survival	7.6	day	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Average survival	8.7	day	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	CC50	100000.0	nM	10.1016/s0960-894x(99)00010-4
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	0.2	%	10.1021/jm00394a039
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	0.3	%	10.1021/jm00394a039
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	0.7	%	10.1021/jm00145a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	3.0	%	10.1021/jm00394a039
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	4.0	%	10.1021/jm00145a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	6.5	%	10.1021/jm00145a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	10.0	%	10.1021/jm00394a039
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	18.0	%	10.1021/jm00394a039
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	21.0	%	10.1021/jm00394a039
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	37.0	%	10.1021/jm00394a039
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	63.0	%	10.1021/jm00394a039
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	85.0	%	10.1021/jm00145a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Control	100.0	%	10.1021/jm00145a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	CPE50	60.0	uM	10.1021/jm00379a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC	1.5	ug ml-1	10.1021/acs.jnatprod.2c00464
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	0.015	ug.mL-1	10.1021/jm061281+
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	0.02	ug.mL-1	10.1021/jm0701472
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	0.06	ug.mL-1	10.1016/S0960-894X(97)00082-6
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	0.077	ug.mL-1	10.1021/jm025569k
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	0.13	ug.mL-1	10.1016/s0960-894x(02)00394-3
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	0.18	ug.mL-1	10.1016/j.bmcl.2008.12.103
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	0.24	ug.mL-1	10.1021/np970341z
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	0.26	ug.mL-1	10.1021/np9703914
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	0.3	ug.mL-1	10.1016/S0960-894X(97)00082-6
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	0.8	ug.mL-1	10.1021/np020234r
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1.054	ug.mL-1	10.1016/s0960-894x(98)00122-x
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1.5	ug.mL-1	10.1007/s00044-011-9574-8
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1.6	ug.mL-1	10.1016/j.bmcl.2012.07.098
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	2.1	ug.mL-1	10.1016/j.bmcl.2012.07.098
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	7.0	ug.mL-1	10.1021/jm0701472
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	11.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	20.0	ug.mL-1	10.1021/jm061281+
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	40.0	ug.mL-1	10.1021/jm0701472
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	70.0	nM	10.1021/acsmedchemlett.5b00318
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	80.0	nM	10.1016/j.ejmech.2013.02.039
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	80.0	nM	10.1016/j.ejmech.2016.09.014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	80.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	140.0	nM	10.1016/j.bmcl.2012.09.079
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	160.0	nM	10.1016/j.ejmech.2022.114443
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	160.0	nM	10.1016/s0960-894x(99)00010-4
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	160.0	nM	10.1021/jm901828c
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	200.0	nM	10.1016/j.bmc.2014.02.056
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	200.0	nM	10.1016/j.bmc.2015.04.079
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	200.0	nM	10.1016/j.ejmech.2012.03.007
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	200.0	nM	10.1016/j.ejmech.2013.06.036
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	200.0	nM	10.1016/j.ejmech.2015.06.024
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	200.0	nM	10.1016/j.ejmech.2016.10.002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	200.0	nM	10.1016/j.ejmech.2018.07.062
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	230.0	nM	10.1016/j.ejmech.2013.09.047
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	270.0	nM	10.1016/j.bmc.2011.04.016
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	300.0	nM	10.1016/j.bmc.2009.04.020
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	300.0	nM	10.1016/j.bmc.2011.06.045
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	300.0	nM	10.1016/j.ejmech.2018.03.008
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	320.0	nM	10.1016/j.ejmech.2013.10.001
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	320.0	nM	10.1021/jm0493966
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	360.0	nM	10.1021/jm990050i
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	380.0	nM	10.1016/j.ejmech.2017.12.018
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	400.0	nM	10.1016/j.bmc.2011.05.037
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	400.0	nM	10.1016/j.bmc.2017.06.046
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	400.0	nM	10.1016/j.bmcl.2008.06.069
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	400.0	nM	10.1016/j.ejmech.2010.12.017
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	400.0	nM	10.1016/j.ejmech.2012.08.042
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	400.0	nM	10.1016/j.ejmech.2013.05.046
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	400.0	nM	10.1021/acs.jmedchem.7b01009
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	400.0	nM	10.1021/jm9007856
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	470.0	nM	10.1021/acsmedchemlett.8b00079
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	480.0	nM	10.1021/jm060030y
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	500.0	nM	10.1016/j.bmc.2012.07.028
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	530.0	nM	10.1016/j.ejmech.2012.07.027
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	600.0	nM	10.1016/j.bmcl.2018.09.019
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	600.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	660.0	nM	10.1021/acs.jmedchem.5b00804
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	760.0	nM	10.1016/j.bmcl.2012.10.047
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	800.0	nM	10.1016/j.bmc.2018.05.034
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	800.0	nM	10.1016/j.ejmech.2022.114618
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	900.0	nM	10.1016/j.bmc.2019.02.005
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	900.0	nM	10.1016/j.ejmech.2019.111739
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	900.0	nM	10.1021/jm040149b
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	950.0	nM	10.1021/np049802o
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1000.0	nM	10.1007/s00044-012-0184-x
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1090.0	nM	10.1007/s00044-007-9035-6
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1090.0	nM	10.1016/j.bmcl.2005.10.111
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1100.0	nM	10.1021/np034052o
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1120.0	nM	10.1021/jm0504306
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1160.0	nM	10.1016/j.bmcl.2011.01.098
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1200.0	nM	10.1016/j.bmc.2014.06.043
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1200.0	nM	10.1016/j.bmc.2015.09.035
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1200.0	nM	10.1016/j.bmcl.2012.05.079
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1200.0	nM	10.1016/j.ejmech.2018.01.086
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1200.0	ug.mL-1	10.1016/j.bmc.2020.115378
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1300.0	nM	10.1016/j.bmc.2009.04.020
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1300.0	nM	10.1128/aac.01447-06
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1400.0	nM	10.1128/aac.01284-06
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1500.0	nM	10.1021/jm040149b
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1700.0	nM	10.1016/j.bmc.2012.08.008
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1700.0	nM	10.1016/j.ejmech.2013.01.015
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	1800.0	nM	10.1016/j.ejmech.2017.09.060
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	2000.0	nM	10.1016/j.bmc.2015.04.079
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	2000.0	nM	10.1016/j.bmcl.2018.09.019
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	2200.0	nM	10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	2200.0	nM	10.1021/jm010226s
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	2220.0	nM	10.1021/jm030241s
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	2800.0	nM	10.1016/j.bmcl.2015.04.006
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3000.0	nM	10.1007/s00044-010-9513-0
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3000.0	nM	10.1007/s00044-012-0342-1
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3000.0	nM	10.1016/j.bmc.2009.05.020
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3000.0	nM	10.1016/j.bmc.2010.02.037
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3000.0	nM	10.1016/j.bmc.2011.10.009
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3000.0	nM	10.1016/j.bmcl.2017.01.032
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3000.0	nM	10.1016/j.ejmech.2012.03.038
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3000.0	nM	10.1016/j.ejmech.2014.07.011
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3000.0	nM	10.1016/j.ejmech.2015.06.027
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3000.0	nM	10.1016/j.ejmech.2015.10.002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3000.0	nM	10.1016/j.ejmech.2020.112790
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3080.0	nM	10.1016/s0960-894x(01)00735-1
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3300.0	nM	10.1016/j.ejmech.2013.12.055
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3500.0	nM	10.1021/jm0607404
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	3600.0	nM	10.1021/acs.jnatprod.1c00400
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	4400.0	nM	10.1021/jm010226s
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	4400.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	6000.0	nM	10.1016/j.bmcl.2007.10.065
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	7300.0	nM	10.1016/j.bmc.2011.06.045
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	8000.0	nM	10.1021/jm034265a
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	10000.0	nM	10.1016/j.ejmech.2010.12.017
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	10000.0	nM	10.1016/j.ejmech.2015.06.024
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	10000.0	nM	10.1016/j.ejmech.2018.07.062
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	10000.0	nM	10.1021/jm040093l
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	10000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	11000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	12000.0	nM	10.1021/jm060030y
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	12000.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	12800.0	ug.mL-1	10.1016/j.bmc.2020.115378
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	13500.0	nM	10.1021/jm040149b
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	16000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	17000.0	nM	10.1016/j.ejmech.2019.111739
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	18000.0	nM	10.1016/j.ejmech.2013.10.001
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	19300.0	nM	10.1128/aac.01435-08
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	22000.0	nM	10.1016/j.bmcl.2012.10.047
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	22000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	23000.0	nM	10.1016/j.ejmech.2013.09.047
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	23000.0	nM	10.1016/s0960-894x(00)00418-2
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	26000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	27100.0	nM	10.1016/j.bmc.2011.04.016
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	29000.0	nM	10.1016/j.ejmech.2013.02.039
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	31000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	35000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	44000.0	nM	10.1016/j.bmcl.2012.09.079
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	50000.0	nM	10.1016/j.bmc.2011.05.037
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	50000.0	nM	10.1016/j.bmc.2014.02.056
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	50000.0	nM	10.1016/j.bmcl.2008.06.069
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	50000.0	nM	10.1021/jm9007856
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	50000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	54000.0	nM	10.1016/j.bmc.2017.06.046
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	60000.0	nM	10.1021/acs.jmedchem.7b01009
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	86600.0	nM	10.1021/jm0504306
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	88000.0	nM	10.1016/j.ejmech.2018.03.008
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	88800.0	nM	10.1021/acsmedchemlett.8b00079
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	88810.0	nM	10.1016/j.ejmech.2017.12.018
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	94000.0	nM	10.1016/j.ejmech.2018.01.086
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	100000.0	nM	10.1016/j.bmc.2019.02.005
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	111100.0	nM	10.1016/j.ejmech.2021.113738
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	112000.0	nM	10.1016/j.ejmech.2013.05.046
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	112000.0	nM	10.1016/j.ejmech.2013.06.036
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	112000.0	nM	10.1016/j.ejmech.2016.09.014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	117600.0	nM	10.1021/jm010226s
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	125000.0	nM	10.1021/jm901828c
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	126000.0	nM	10.1016/j.bmc.2018.05.034
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	126000.0	nM	10.1016/j.ejmech.2022.114618
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	212000.0	nM	10.1016/j.ejmech.2012.07.027
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	250000.0	nM	10.1007/s00044-012-0184-x
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	250000.0	nM	10.1016/j.ejmech.2012.03.007
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	250000.0	nM	10.1016/j.ejmech.2012.08.042
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	250000.0	nM	10.1016/j.ejmech.2016.10.002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	444000.0	nM	10.1128/aac.01447-06
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	530000.0	nM	10.1016/j.bmc.2012.08.008
Human alphaherpesvirus 1	Human alphaherpesvirus 1	EC50	nan	None	10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ED50	0.02	ug ml-1	10.1021/jm00172a026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ED50	0.08	ug ml-1	10.1021/jm00167a002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ED50	0.14	ug ml-1	10.1021/jm9701536
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ED50	0.2	uM	10.1016/S0960-894X(00)80318-2
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ED50	0.5	mg.kg-1	10.1021/acs.jmedchem.2c00668
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ED50	0.5	uM	10.1021/jm030206l
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ED50	1.0	ug ml-1	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ED50	12.3	ug ml-1	10.1021/jm00384a033
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ED50	50.0	mg.kg-1	10.1021/jm00107a006
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ED50	58.0	mg.kg-1	10.1021/jm00107a006
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ED50	189.9	ug ml-1	10.1021/jm00167a002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	FC	4.3	None	10.1021/acsmedchemlett.5b00318
Human alphaherpesvirus 1	Human alphaherpesvirus 1	FC	8.5	None	10.1021/acsmedchemlett.5b00318
Human alphaherpesvirus 1	Human alphaherpesvirus 1	FC	100.0	None	10.1021/acs.jnatprod.2c00464
Human alphaherpesvirus 1	Human alphaherpesvirus 1	FC	2300.0	None	10.1021/acsmedchemlett.5b00318
Human alphaherpesvirus 1	Human alphaherpesvirus 1	FC	10000.0	None	10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	0.00475	nM	10.1021/acs.jnatprod.7b00193
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	0.01	ug.mL-1	10.1016/s0960-894x(01)00270-0
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	0.1	ug.mL-1	10.1021/np0501886
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	0.2	ug.mL-1	10.1021/np300636k
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	0.25	ug.mL-1	10.1021/np050498o
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	0.5	ug.mL-1	10.1021/np0602012
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	1.1	ug.mL-1	10.1021/np0503202
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	2.0	ug.mL-1	10.1021/np0004404
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	2.6	ug.mL-1	10.1021/jm00402a016
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	6.86	ug.mL-1	10.1021/np900082h
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	9.6	ug.mL-1	10.1016/s0960-894x(01)00270-0
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	100.0	nM	10.1021/jm00144a033
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	100.0	ug.mL-1	10.1021/jm00402a016
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	150.0	nM	10.1021/acs.jnatprod.7b00620
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	200.0	nM	10.1016/S0960-894X(97)00117-0
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	300.0	nM	10.1016/j.bmcl.2011.02.037
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	320.0	nM	10.1016/j.bmc.2008.10.081
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	390.0	nM	10.1016/j.bmcl.2007.02.079
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	390.0	nM	10.1016/j.bmcl.2007.11.120
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	400.0	nM	10.1016/S0960-894X(00)80317-0
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	410.0	nM	10.1021/acs.jnatprod.6b00585
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	410.0	nM	10.1021/acs.jnatprod.7b01074
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	580.0	nM	10.1016/j.bmc.2008.10.081
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	600.0	nM	10.1021/jm2001426
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	990.0	nM	10.1016/j.bmc.2011.02.007
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	1290.0	nM	10.1016/j.bmcl.2018.08.040
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	1380.0	nM	10.1016/j.ejmech.2019.01.076
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	1700.0	nM	10.1021/jm00044a015
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	1730.0	nM	10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	1800.0	nM	10.1021/jm950029r
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	2100.0	nM	10.1016/j.bmcl.2007.03.102
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	2100.0	nM	10.1016/j.bmcl.2007.05.010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	2100.0	nM	10.1016/j.bmcl.2008.06.060
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	2100.0	nM	10.1016/j.bmcl.2010.03.115
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	2600.0	nM	10.1021/jm00119a006
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	2600.0	nM	10.1021/jm00403a005
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	2900.0	nM	10.1016/j.bmc.2012.04.049
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	3040.0	nM	10.1016/j.bmc.2008.10.081
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	3400.0	nM	10.1021/jm00081a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	3400.0	nM	10.1021/jm950835y
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	3500.0	nM	10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	3500.0	nM	10.1016/j.ejmech.2020.112790
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	3900.0	nM	10.1021/jm00062a006
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	3900.0	nM	10.1021/jm00127a003
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	3900.0	nM	10.1021/jm00169a027
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	4000.0	nM	10.1021/jm00169a028
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	4000.0	nM	10.1021/jm00174a011
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	4300.0	nM	10.1021/np800760p
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	4300.0	nM	10.1021/np900530n
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	4800.0	nM	10.1021/jm00105a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	7000.0	nM	10.1021/jm00169a028
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	9510.0	nM	10.1016/j.bmc.2008.10.081
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	10200.0	nM	10.1021/np070689m
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	13000.0	nM	10.1021/np900650c
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	17000.0	nM	10.1021/np100849x
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	17300.0	nM	10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	27400.0	nM	10.1016/j.bmcl.2020.127559
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	27800.0	nM	10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	31200.0	nM	10.1016/j.bmc.2008.10.081
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	75070.0	nM	10.1016/j.bmc.2008.10.081
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	350000.0	nM	10.1021/jm990050i
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	444000.0	nM	10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC50	nan	None	10.1016/j.ejmech.2019.01.076
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC90	7000.0	nM	10.1021/jm00174a011
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC95	6900.0	nM	10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC95	13900.0	nM	10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC95	111000.0	nM	10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC95	138800.0	nM	10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1	Human alphaherpesvirus 1	IC95	444000.0	nM	10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	0.05	ug ml-1	10.1021/jm00377a018
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	0.2	ug ml-1	10.1021/jm00107a006
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	0.4	uM	10.1021/jm00147a020
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	0.48	uM	10.1021/jm00397a022
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	0.5	ug ml-1	10.1021/jm00127a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	0.5	ug ml-1	10.1021/jm00166a019
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	0.7	ug ml-1	10.1021/jm00117a004
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	0.8	ug ml-1	10.1021/jm00353a011
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	0.9	uM	10.1021/jm00061a013
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	1.3	uM	10.1021/jm00122a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	4.3	ug ml-1	10.1021/jm00127a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	100.0	ug ml-1	10.1021/jm00167a002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	ID50	440.0	uM	10.1021/jm00061a013
Human alphaherpesvirus 1	Human alphaherpesvirus 1	INH	0.0043	mM	10.1021/np900290s
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	0.0	%	10.1021/jm00045a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	85.0	%	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	86.0	%	10.1021/jm00155a039
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	94.0	%	10.1016/j.bmcl.2012.07.098
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	95.0	%	10.1016/j.bmc.2011.02.007
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	96.0	%	10.1007/s00044-007-9035-6
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	96.0	%	10.1016/j.bmcl.2005.10.111
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	100.0	%	10.1021/jm00045a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	nan	%	10.1016/j.bmc.2013.07.031
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	nan	%	10.1016/j.bmcl.2012.05.079
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	nan	%	10.1016/j.bmcl.2012.06.031
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Inhibition	nan	%	10.1021/acsmedchemlett.7b00364
Human alphaherpesvirus 1	Human alphaherpesvirus 1	log(activity)	2.42	None	10.1016/j.ejmech.2022.114443
Human alphaherpesvirus 1	Human alphaherpesvirus 1	log(activity)	3.36	None	10.1016/j.ejmech.2022.114443
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MDD	7.8	None	10.1021/jm00167a002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MDD	8.0	None	10.1021/jm00167a002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MDD	12.3	None	10.1021/jm00167a002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.003	ug.mL-1	10.1021/jm991171l
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.004	ug.mL-1	10.1016/S0960-894X(96)00244-2
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.004	ug.mL-1	10.1021/jm00045a025
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.02	ug.mL-1	10.1016/S0960-894X(96)00254-5
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.02	ug.mL-1	10.1021/jm00066a013
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.02	ug.mL-1	10.1021/jm991171l
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.08	ug.mL-1	10.1021/jm010922s
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.1	ug.mL-1	10.1021/jm00402a017
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.13	ug.mL-1	10.1021/jm010922s
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.2	ug.mL-1	10.1021/jm00402a017
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.3	ug.mL-1	10.1021/jm00149a024
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.384	ug.mL-1	10.1016/j.ejmech.2007.04.010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.4	ug.mL-1	10.1021/jm00066a013
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	0.7	ug.mL-1	10.1021/jm00066a013
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	1.563	ug.mL-1	10.1016/S0960-894X(97)00365-X
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	2.4	ug.mL-1	10.1007/s00044-012-0127-6
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	4.0	ug.mL-1	10.1016/S0960-894X(96)00254-5
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	5.0	ug.mL-1	10.1021/jm00045a025
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	7.1	ug.mL-1	10.1021/jm010922s
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	10.0	nM	10.1021/jm00117a026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	19.0	ug.mL-1	10.1021/jm010922s
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	20.0	ug.mL-1	10.1021/jm00402a017
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	48.0	ug.mL-1	10.1016/j.ejmech.2007.04.010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	70.0	ug.mL-1	10.1021/jm00045a025
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	70.0	ug.mL-1	10.1021/jm00066a013
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	80.0	ug.mL-1	10.1016/S0960-894X(96)00254-5
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	100.0	ug.mL-1	10.1021/jm00035a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	300.0	ug.mL-1	10.1007/s00044-012-0127-6
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	400.0	nM	10.1021/jm070324z
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	480.0	nM	10.1016/j.bmc.2006.10.046
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	480.0	nM	10.1021/np060435l
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	1300.0	nM	10.1021/jm00117a026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	4400.0	nM	10.1021/jm00117a026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	13200.0	nM	10.1021/jm00117a026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	44000.0	nM	10.1021/jm00117a026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	60000.0	nM	10.1016/j.bmc.2006.10.046
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	60000.0	nM	10.1021/np060435l
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC	440000.0	nM	10.1021/jm00117a026
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC50	0.384	ug.mL-1	10.1021/jm050772b
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC50	0.4	ug.mL-1	10.1016/j.ejmech.2009.02.030
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC50	3.0	ug.mL-1	10.1021/jm00389a019
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC50	48.0	ug.mL-1	10.1021/jm050772b
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MIC50	50.0	ug.mL-1	10.1016/j.ejmech.2009.02.030
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Mice with lesions	6.0	None	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Mice with lesions	8.0	None	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Mice with lesions	10.0	None	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	MNTD	6.7	uM	10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Plaque inhibition result	nan	None	10.1021/jm00144a033
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Ratio	1000.0	None	10.1016/j.ejmech.2009.10.010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Survivors	0.0	None	10.1021/jm00107a006
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Survivors	0.0	None	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Survivors	1.0	None	10.1021/jm00107a006
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Survivors	1.0	None	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Survivors	2.0	None	10.1021/jm00107a006
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Survivors	2.0	None	10.1021/jm00145a014
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Survivors	3.0	None	10.1021/jm00107a006
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Survivors	8.0	None	10.1021/jm00107a006
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Survivors / treated	0.0	None	10.1021/jm00167a002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Survivors / treated	2.0	None	10.1021/jm00167a002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Survivors / treated	4.0	None	10.1021/jm00167a002
Human alphaherpesvirus 1	Human alphaherpesvirus 1	TCID50	0.012	ug ml-1	10.1016/j.ejmech.2010.05.069
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Therapeutic index	38.0	None	10.1021/jm00402a016
Human alphaherpesvirus 1	Human alphaherpesvirus 1	Virus rating	6.7	None	10.1021/jm00117a004
Human alphaherpesvirus 1	Human alphaherpesvirus 1	VR	0.0	None	10.1021/jm00389a019
Human alphaherpesvirus 1	Human alphaherpesvirus 1	VR	1.4	None	10.1021/jm00142a010
Human alphaherpesvirus 1	Human alphaherpesvirus 1	VR	5.7	None	10.1021/jm00389a019
Human alphaherpesvirus 1	Human alphaherpesvirus 1	VR	6.3	None	10.1021/jm00384a033
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Activity	6.0	ug ml-1	10.1021/np010206t
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Activity	6.0	ug ml-1	10.1021/np010207l
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	0.018	ug.mL-1	10.1021/jm061281+
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	0.02	ug.mL-1	10.1021/jm0707166
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	0.048	ug.mL-1	10.1021/jm061281+
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	0.05	ug.mL-1	10.1021/jm0707166
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	0.07	ug.mL-1	10.1021/jm0701472
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	0.2	ug.mL-1	10.1016/S0960-894X(97)00082-6
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	0.22	ug.mL-1	10.1021/np970341z
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	0.36	ug.mL-1	10.1016/j.bmcl.2008.12.103
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	0.88	ug.mL-1	10.1016/s0960-894x(02)00394-3
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	1.1	ug.mL-1	10.1016/S0960-894X(97)00082-6
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	1.5	ug.mL-1	10.1021/np960613i
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	2.3	ug.mL-1	10.1021/np9601871
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	2.3	ug.mL-1	10.1021/np9703914
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	2.4	ug.mL-1	10.1021/np020234r
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	5.12	ug.mL-1	10.1016/s0960-894x(98)00122-x
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	80.0	nM	10.1016/j.bmc.2015.04.079
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	80.0	nM	10.1016/j.ejmech.2013.02.039
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	100.0	nM	10.1016/j.bmc.2014.02.056
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	100.0	nM	10.1016/j.ejmech.2015.06.024
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	140.0	nM	10.1016/j.bmcl.2012.09.079
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	180.0	nM	10.1016/j.bmc.2017.06.046
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	200.0	nM	10.1016/j.bmcl.2008.06.069
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	200.0	nM	10.1016/j.ejmech.2010.12.017
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	200.0	nM	10.1016/j.ejmech.2013.05.046
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	200.0	nM	10.1016/j.ejmech.2013.06.036
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	200.0	nM	10.1016/j.ejmech.2013.09.047
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	200.0	nM	10.1016/j.ejmech.2016.09.014
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	200.0	nM	10.1016/j.ejmech.2018.07.062
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	200.0	nM	10.1021/jm9007856
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	230.0	nM	10.1016/j.bmc.2011.04.016
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	230.0	nM	10.1016/j.bmc.2011.06.045
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	270.0	nM	10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	290.0	nM	10.1016/j.ejmech.2017.12.018
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	290.0	nM	10.1016/j.ejmech.2018.03.008
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	300.0	nM	10.1021/jm901828c
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	340.0	nM	10.1021/acsmedchemlett.8b00079
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	380.0	nM	10.1016/j.ejmech.2012.07.027
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	400.0	nM	10.1016/j.bmc.2011.05.037
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	400.0	nM	10.1016/j.bmc.2018.05.034
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	400.0	nM	10.1016/j.ejmech.2012.03.007
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	400.0	nM	10.1016/j.ejmech.2012.08.042
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	400.0	nM	10.1016/j.ejmech.2016.10.002
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	400.0	nM	10.1016/j.ejmech.2022.114618
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	400.0	nM	10.1021/acs.jmedchem.7b01009
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	480.0	nM	10.1021/jm060030y
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	500.0	nM	10.1016/j.ejmech.2013.10.001
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	600.0	nM	10.1016/j.bmcl.2018.09.019
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	700.0	nM	10.1007/s00044-012-0184-x
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	700.0	nM	10.1016/j.ejmech.2018.01.086
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	900.0	nM	10.1016/j.bmc.2019.02.005
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	950.0	nM	10.1021/np049802o
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	1000.0	nM	10.1021/np034052o
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	1020.0	nM	10.1021/acs.jmedchem.5b00804
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	1100.0	nM	10.1021/jm990050i
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	1200.0	nM	10.1016/j.bmc.2009.04.020
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	1440.0	nM	10.1016/j.ejmech.2022.114443
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	1720.0	nM	10.1016/j.bmcl.2011.01.098
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	1760.0	nM	10.1021/jm0504306
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	1870.0	nM	10.1016/j.bmcl.2012.05.079
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	2000.0	nM	10.1016/j.ejmech.2019.111739
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	3000.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	3100.0	nM	10.1128/aac.01447-06
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	4600.0	nM	10.1021/acs.jnatprod.1c00400
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	4700.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	4900.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	6000.0	nM	10.1016/j.bmcl.2008.06.069
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	6160.0	nM	10.1016/s0960-894x(01)00735-1
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	6200.0	nM	10.1021/jm010226s
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	6600.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	6700.0	nM	10.1021/jm040149b
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	9600.0	nM	10.1016/j.ejmech.2013.12.055
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	9600.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	10210.0	nM	10.1021/jm030241s
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	11000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	18000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	19300.0	nM	10.1128/aac.01435-08
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	24000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	32300.0	nM	10.1021/jm040149b
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	33000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	35000.0	nM	10.1016/s0960-894x(00)00418-2
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	42000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	43000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	50000.0	nM	10.1128/aac.00669-10
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	58600.0	nM	10.1016/j.ejmech.2013.01.015
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	100000.0	nM	10.1016/j.bmcl.2008.06.069
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	100000.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	440000.0	nM	10.1128/aac.00417-09
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	444000.0	nM	10.1128/aac.01447-06
Human alphaherpesvirus 2	Human alphaherpesvirus 2	EC50	nan	None	10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ED50	0.06	ug ml-1	10.1021/jm00167a002
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ED50	0.07	ug ml-1	10.1021/jm00167a002
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ED50	0.09	ug ml-1	10.1021/jm00167a002
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ED50	0.1	ug ml-1	10.1021/jm00167a002
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ED50	0.23	ug ml-1	10.1021/jm9701536
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ED50	0.4	uM	10.1016/S0960-894X(00)80318-2
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ED50	0.5	mg.kg-1	10.1021/acs.jmedchem.2c00668
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ED50	1.0	ug ml-1	10.1021/jm00145a014
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ED50	2.5	uM	10.1021/jm030206l
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ED50	4.8	ug ml-1	10.1021/jm00384a033
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ED50	58.0	mg.kg-1	10.1021/jm00107a006
Human alphaherpesvirus 2	Human alphaherpesvirus 2	FC	1000.0	None	10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	0.00311	nM	10.1021/acs.jnatprod.7b00193
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	0.02	ug.mL-1	10.1016/s0960-894x(01)00270-0
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	4.21	ug.mL-1	10.1021/np010207l
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	400.0	nM	10.1016/S0960-894X(00)80317-0
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	1200.0	nM	10.1021/jm00105a010
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	1270.0	nM	10.1016/j.bmcl.2011.02.037
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	2100.0	nM	10.1016/S0960-894X(97)00117-0
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	2800.0	nM	10.1016/j.bmc.2012.04.049
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	3230.0	nM	10.1016/j.ejmech.2019.01.076
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	4300.0	nM	10.1021/jm00062a006
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	31000.0	nM	10.1021/acs.jnatprod.9b01242
Human alphaherpesvirus 2	Human alphaherpesvirus 2	IC50	350000.0	nM	10.1021/jm990050i
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ID50	0.04	ug ml-1	10.1021/jm00377a018
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ID50	0.3	ug ml-1	10.1021/jm00127a010
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ID50	0.6	ug ml-1	10.1021/jm00107a006
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ID50	1.5	uM	10.1021/jm00147a020
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ID50	1.6	uM	10.1021/jm00397a022
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ID50	2.2	uM	10.1021/jm00122a014
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ID50	2.4	ug ml-1	10.1021/jm00166a019
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ID50	5.3	ug ml-1	10.1021/jm00117a004
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ID50	100.0	ug ml-1	10.1021/jm00167a002
Human alphaherpesvirus 2	Human alphaherpesvirus 2	ID50	440.0	uM	10.1021/jm00061a013
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Inhibition	34.0	%	10.1021/jm00145a014
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Inhibition	60.6	%	10.1021/np200493t
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Inhibition	66.3	%	10.1021/np200493t
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Inhibition	nan	%	10.1016/j.bmc.2013.07.031
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Inhibition	nan	%	10.1016/j.bmcl.2012.05.079
Human alphaherpesvirus 2	Human alphaherpesvirus 2	log(activity)	1.79	None	10.1016/j.ejmech.2022.114443
Human alphaherpesvirus 2	Human alphaherpesvirus 2	log(activity)	2.9	None	10.1016/j.ejmech.2022.114443
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MED	12.0	mg kg-1	10.1021/jm00063a008
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	0.004	ug.mL-1	10.1016/S0960-894X(96)00244-2
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	0.02	ug.mL-1	10.1021/jm00066a013
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	0.03	ug.mL-1	10.1016/S0960-894X(96)00254-5
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	0.07	ug.mL-1	10.1021/jm00402a017
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	0.07	ug.mL-1	10.1021/jm010922s
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	0.19	ug.mL-1	10.1021/jm010922s
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	0.2	ug.mL-1	10.1021/jm00402a017
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	0.28	ug.mL-1	10.1021/jm010922s
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	0.384	ug.mL-1	10.1016/j.ejmech.2007.04.010
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	0.7	ug.mL-1	10.1021/jm00066a013
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	1.3	ug.mL-1	10.1021/jm00063a008
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	2.0	ug.mL-1	10.1021/jm00066a013
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	3.0	ug.mL-1	10.1021/jm00149a024
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	20.0	ug.mL-1	10.1007/s00044-012-0127-6
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	400.0	nM	10.1021/jm070324z
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	480.0	nM	10.1021/np060435l
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	800.0	nM	10.1016/j.bmc.2006.10.046
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	132000.0	nM	10.1021/jm00117a026
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC	440000.0	nM	10.1021/jm00117a026
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC50	0.384	ug.mL-1	10.1021/jm050772b
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MIC50	0.4	ug.mL-1	10.1016/j.ejmech.2009.02.030
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MNTD	6.7	uM	10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MTD	200.0	mg kg-1	10.1021/jm00063a008
Human alphaherpesvirus 2	Human alphaherpesvirus 2	MTL	200.0	ug ml-1	10.1021/jm00063a008
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Ratio	100000.0	None	10.1021/np010207l
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Ratio EC50	100.0	None	10.1128/aac.00417-09
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Survivors	0.0	None	10.1021/jm00107a006
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Survivors	1.0	None	10.1021/jm00107a006
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Survivors	2.0	None	10.1021/jm00107a006
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Survivors	3.0	None	10.1021/jm00107a006
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Survivors	7.0	None	10.1021/jm00107a006
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Virus rating	4.5	None	10.1021/jm00117a004
Human alphaherpesvirus 2	Human alphaherpesvirus 2	Virus rating	5.1	None	10.1021/jm00388a036
Human alphaherpesvirus 2	Human alphaherpesvirus 2	VR	4.8	None	10.1021/jm00384a033
Human alphaherpesvirus 3	Human alphaherpesvirus 3	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Human alphaherpesvirus 3	Human alphaherpesvirus 3	CC50	200000.0	nM	10.1021/jm000210m
Human alphaherpesvirus 3	Human alphaherpesvirus 3	CC50	488000.0	nM	10.1021/jm030241s
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	0.17	ug.mL-1	10.1016/j.ejmech.2007.04.010
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	0.22	ug.mL-1	10.1021/jm051023x
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	0.23	ug.mL-1	10.1021/jm0707166
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	0.24	ug.mL-1	10.1016/j.bmc.2008.09.027
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	0.44	ug.mL-1	10.1007/s00044-011-9776-0
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	0.6	ug.mL-1	10.1016/S0960-894X(97)00082-6
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	0.6	ug.mL-1	10.1021/jm040869i
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	0.7	ug.mL-1	10.1016/j.bmc.2007.03.061
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	0.75	ug.mL-1	10.1021/jm061281+
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	9.0	nM	10.1016/j.ejmech.2021.113467
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	9.4	ug.mL-1	10.1021/jm040869i
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	10.2	ug.mL-1	10.1021/jm0707166
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	13.0	ug.mL-1	10.1016/j.bmc.2008.09.027
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	14.0	ug.mL-1	10.1021/jm051023x
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	16.0	ug.mL-1	10.1016/j.ejmech.2007.04.010
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	23.0	ug.mL-1	10.1007/s00044-011-9776-0
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	25.1	ug.mL-1	10.1021/jm061281+
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	26.0	nM	10.1016/j.ejmech.2013.05.046
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	28.0	ug.mL-1	10.1016/j.bmc.2007.03.061
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	30.0	nM	10.1021/jm0607404
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	490.0	nM	10.1016/j.ejmech.2012.03.007
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	490.0	nM	10.1016/j.ejmech.2020.112884
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	700.0	nM	10.1016/j.ejmech.2022.114255
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	700.0	nM	10.1016/j.ejmech.2022.114618
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	800.0	nM	10.1016/j.ejmech.2016.10.002
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	840.0	nM	10.1016/j.bmcl.2009.12.102
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1000.0	nM	10.1016/j.ejmech.2010.12.017
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1000.0	nM	10.1016/s0960-894x(00)00193-1
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1000.0	nM	10.1016/s0960-894x(00)00672-7
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1000.0	nM	10.1021/jm000210m
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1000.0	nM	10.1021/jm0614329
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1000.0	nM	10.1021/jm070324z
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1000.0	nM	10.1021/jm070357e
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1000.0	nM	10.1021/jm990346o
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1100.0	nM	10.1016/j.bmcl.2004.03.029
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1100.0	nM	10.1016/j.ejmech.2011.02.014
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1100.0	nM	10.1021/jm8014662
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1260.0	nM	10.1016/j.ejmech.2018.07.062
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1400.0	nM	10.1016/j.bmc.2011.05.037
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1400.0	nM	10.1021/jm050867d
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1400.0	nM	10.1021/jm070210n
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1500.0	nM	10.1016/j.bmc.2015.04.079
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1500.0	nM	10.1016/j.bmc.2017.06.046
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1500.0	nM	10.1016/j.bmcl.2004.03.029
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1560.0	nM	10.1016/j.bmc.2011.06.045
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1560.0	nM	10.1016/j.ejmech.2019.111739
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1600.0	nM	10.1021/acsmedchemlett.0c00485
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1600.0	nM	10.1021/jm040093l
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1640.0	nM	10.1016/j.ejmech.2012.07.027
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1690.0	nM	10.1016/j.ejmech.2015.06.024
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1800.0	nM	10.1016/j.ejmech.2009.03.005
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1820.0	nM	10.1016/j.bmc.2015.09.033
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	1880.0	nM	10.1021/acs.jmedchem.7b01009
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2000.0	nM	10.1016/j.ejmech.2009.03.005
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2000.0	nM	10.1021/jm990543n
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2100.0	nM	10.1016/j.ejmech.2013.06.036
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2180.0	nM	10.1016/j.ejmech.2012.04.001
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2350.0	nM	10.1016/j.ejmech.2018.06.028
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2400.0	nM	10.1021/jm030241s
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2500.0	nM	10.1016/j.bmcl.2008.06.069
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2500.0	nM	10.1016/j.ejmech.2012.04.001
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2600.0	nM	10.1016/j.bmc.2014.02.056
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2600.0	nM	10.1021/jm010226s
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2600.0	nM	10.1021/jm010227k
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2700.0	nM	10.1016/j.ejmech.2012.08.042
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2840.0	nM	10.1016/j.ejmech.2012.07.027
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2840.0	nM	10.1021/acsmedchemlett.8b00079
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2900.0	nM	10.1016/j.bmcl.2008.06.069
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2900.0	nM	10.1016/s0960-894x(00)00193-1
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2900.0	nM	10.1016/s0960-894x(00)00672-7
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2900.0	nM	10.1021/jm000210m
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2900.0	nM	10.1021/jm070357e
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2900.0	nM	10.1021/jm990346o
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	2930.0	nM	10.1016/j.ejmech.2018.01.086
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	3000.0	nM	10.1016/j.bmc.2011.04.016
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	3020.0	nM	10.1021/acs.jmedchem.7b00416
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	3300.0	nM	10.1021/jm1011462
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	3370.0	nM	10.1016/j.ejmech.2018.03.008
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	3550.0	nM	10.1016/j.bmc.2018.05.034
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	3640.0	nM	10.1016/j.bmc.2011.06.045
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	4000.0	nM	10.1016/s0960-894x(00)00672-7
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	4000.0	nM	10.1021/jm070210n
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	4170.0	nM	10.1021/acs.jmedchem.2c00667
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	4170.0	nM	10.1039/d1md00086a
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	4400.0	nM	10.1016/j.bmc.2009.04.020
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	4900.0	nM	10.1016/j.bmc.2011.05.037
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	5000.0	nM	10.1016/j.bmc.2019.02.005
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	5310.0	nM	10.1016/j.ejmech.2017.12.018
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	6400.0	nM	10.1021/acs.jmedchem.5b00804
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	7060.0	nM	10.1021/acsmedchemlett.0c00090
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	7100.0	nM	10.1021/acs.jmedchem.2c00667
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	8500.0	nM	10.1128/aac.01447-06
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	8810.0	nM	10.1016/s0960-894x(01)00735-1
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	12000.0	nM	10.1016/j.ejmech.2021.113467
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	14120.0	nM	10.1016/j.ejmech.2018.03.008
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	14650.0	nM	10.1016/j.ejmech.2022.114857
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	14740.0	nM	10.1016/j.ejmech.2022.114618
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	14870.0	nM	10.1016/j.bmc.2018.05.034
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	15000.0	nM	10.1016/j.ejmech.2012.08.042
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	16500.0	nM	10.1016/j.ejmech.2010.12.017
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	19000.0	nM	10.1021/jm030241s
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	20700.0	nM	10.1021/acs.jmedchem.7b00416
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	22150.0	nM	10.1021/acsmedchemlett.0c00485
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	23220.0	nM	10.1016/j.ejmech.2020.112884
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	24000.0	nM	10.1021/jm050867d
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	24000.0	nM	10.1021/jm070210n
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	26000.0	nM	10.1016/j.ejmech.2013.06.036
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	26600.0	nM	10.1016/j.ejmech.2012.03.007
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	26700.0	nM	10.1016/j.bmcl.2009.12.102
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	27000.0	nM	10.1016/j.ejmech.2016.04.034
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	30000.0	nM	10.1021/jm030241s
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	32000.0	nM	10.1021/jm0614329
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	32000.0	nM	10.1021/jm070324z
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	33000.0	nM	10.1016/j.bmc.2015.04.079
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	36000.0	nM	10.1021/jm050867d
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	36000.0	nM	10.1021/jm070210n
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	36740.0	nM	10.1016/j.ejmech.2018.07.062
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	37000.0	nM	10.1016/j.ejmech.2012.07.027
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	38900.0	nM	10.1016/j.bmc.2017.06.046
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	40000.0	nM	10.1016/j.bmcl.2004.03.029
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	42700.0	nM	10.1021/acsmedchemlett.0c00090
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	43000.0	nM	10.1016/j.bmc.2011.05.037
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	43000.0	nM	10.1016/j.bmcl.2008.06.069
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	49300.0	nM	10.1016/j.ejmech.2015.06.024
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	50300.0	nM	10.1016/j.ejmech.2016.10.002
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	53510.0	nM	10.1016/j.ejmech.2017.12.018
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	54000.0	nM	10.1016/j.ejmech.2012.07.027
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	54400.0	nM	10.1016/j.ejmech.2018.01.086
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	54500.0	nM	10.1016/j.bmc.2015.09.033
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	54800.0	nM	10.1021/acsmedchemlett.8b00079
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	56000.0	nM	10.1016/j.ejmech.2021.113467
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	59200.0	nM	10.1016/j.bmc.2019.02.005
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	61000.0	nM	10.1016/j.bmcl.2008.06.069
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	62000.0	nM	10.1021/jm1011462
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	62200.0	nM	10.1016/j.ejmech.2009.03.005
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	69300.0	nM	10.1016/j.bmc.2011.04.016
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	71600.0	nM	10.1016/j.bmc.2011.06.045
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	72000.0	nM	10.1021/jm8014662
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	73000.0	nM	10.1021/acs.jmedchem.7b01009
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	74000.0	nM	10.1016/s0960-894x(00)00193-1
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	74000.0	nM	10.1021/jm000210m
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	74000.0	nM	10.1021/jm070357e
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	74000.0	nM	10.1021/jm990346o
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	76900.0	nM	10.1016/j.bmc.2011.06.045
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	84630.0	nM	10.1016/j.ejmech.2022.114857
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	92000.0	nM	10.1016/j.ejmech.2012.04.001
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	96000.0	nM	10.1016/j.ejmech.2019.111739
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	111000.0	nM	10.1016/j.bmc.2011.05.037
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	125000.0	nM	10.1016/s0960-894x(00)00193-1
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	125000.0	nM	10.1016/s0960-894x(00)00672-7
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	125000.0	nM	10.1021/jm000210m
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	125000.0	nM	10.1021/jm070357e
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	125000.0	nM	10.1021/jm990346o
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	133300.0	nM	10.1016/j.ejmech.2018.06.028
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	140000.0	nM	10.1016/j.bmc.2014.02.056
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	143600.0	nM	10.1016/j.ejmech.2013.05.046
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC50	275830.0	nM	10.1021/acs.jmedchem.2c00667
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC90	30.23	uM	10.1021/acs.jmedchem.2c00667
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC90	30.23	uM	10.1039/d1md00086a
Human alphaherpesvirus 3	Human alphaherpesvirus 3	EC90	nan	None	10.1016/j.ejmech.2011.02.014
Human alphaherpesvirus 3	Human alphaherpesvirus 3	ED50	1.0	ug ml-1	10.1021/jm00145a014
Human alphaherpesvirus 3	Human alphaherpesvirus 3	ED50	2.0	uM	10.1016/S0960-894X(00)80318-2
Human alphaherpesvirus 3	Human alphaherpesvirus 3	ED50	2.3	ug ml-1	10.1021/jm00167a002
Human alphaherpesvirus 3	Human alphaherpesvirus 3	ED50	2.7	ug ml-1	10.1021/jm9701536
Human alphaherpesvirus 3	Human alphaherpesvirus 3	ED50	3.7	ug ml-1	10.1021/jm00167a002
Human alphaherpesvirus 3	Human alphaherpesvirus 3	FC	1.8	None	10.1021/acsmedchemlett.5b00318
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	0.18	ug.mL-1	10.1021/jm960314q
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	0.35	ug.mL-1	10.1016/s0960-894x(02)00535-8
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	0.35	ug.mL-1	10.1021/jm960314q
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	0.38	ug.mL-1	10.1016/s0960-894x(02)00535-8
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	0.73	ug.mL-1	10.1021/jm980327z
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	0.78	ug.mL-1	10.1021/jm980327z
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	0.82	ug.mL-1	10.1021/jm981051y
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	0.95	ug.mL-1	10.1021/jm981051y
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	1.1	ug.mL-1	10.1016/s0960-894x(01)00270-0
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	3.1	ug.mL-1	10.1016/s0960-894x(02)00535-8
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	6.5	ug.mL-1	10.1016/s0960-894x(02)00535-8
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	11.0	ug.mL-1	10.1021/jm960314q
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	13.0	ug.mL-1	10.1016/s0960-894x(01)00270-0
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	22.0	ug.mL-1	10.1021/jm960314q
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	24.0	ug.mL-1	10.1021/jm980327z
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	25.0	ug.mL-1	10.1021/jm981051y
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	26.0	ug.mL-1	10.1021/jm980327z
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	40.0	ug.mL-1	10.1021/jm981051y
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	1900.0	nM	10.1016/j.bmc.2012.04.049
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	2000.0	nM	10.1016/S0960-894X(00)80317-0
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	4090.0	nM	10.1021/jm000118q
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	4530.0	nM	10.1021/jm000118q
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	5800.0	nM	10.1016/j.bmc.2010.12.052
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	8100.0	nM	10.1016/j.bmcl.2007.03.102
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	8100.0	nM	10.1016/j.bmcl.2007.05.010
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	8100.0	nM	10.1016/j.bmcl.2008.06.060
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	8100.0	nM	10.1016/j.bmcl.2010.01.094
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	8100.0	nM	10.1016/j.bmcl.2010.03.115
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	13000.0	nM	10.1016/j.bmcl.2012.11.017
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	15000.0	nM	10.1021/jm00105a010
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	21000.0	nM	10.1021/jm00062a006
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	41000.0	nM	10.1021/jm000118q
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	46800.0	nM	10.1021/jm950029r
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	58700.0	nM	10.1016/j.bmc.2010.12.052
Human alphaherpesvirus 3	Human alphaherpesvirus 3	IC50	63000.0	nM	10.1021/jm000118q
Human alphaherpesvirus 3	Human alphaherpesvirus 3	ID50	2.0	uM	10.1021/jm00061a013
Human alphaherpesvirus 3	Human alphaherpesvirus 3	ID50	4.0	uM	10.1021/jm00061a013
Human alphaherpesvirus 3	Human alphaherpesvirus 3	ID50	100.0	ug ml-1	10.1021/jm00167a002
Human alphaherpesvirus 3	Human alphaherpesvirus 3	ID50	100.0	uM	10.1021/jm00061a013
Human alphaherpesvirus 3	Human alphaherpesvirus 3	Inhibition	nan	%	10.1016/j.bmc.2013.07.031
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MCC	200000.0	nM	10.1021/jm000210m
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MCC	200000.0	nM	10.1021/jm030241s
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	0.04	ug.mL-1	10.1021/jm00066a013
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	0.15	ug.mL-1	10.1021/jm00066a013
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	0.18	ug.mL-1	10.1021/jm00045a025
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	0.3	ug.mL-1	10.1021/jm00402a017
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	0.38	ug.mL-1	10.1021/jm00045a025
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	0.5	ug.mL-1	10.1016/S0960-894X(96)00244-2
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	0.6	ug.mL-1	10.1021/jm00402a017
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	0.8	ug.mL-1	10.1021/jm991171l
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	0.82	ug.mL-1	10.1021/jm9507901
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	0.95	ug.mL-1	10.1021/jm9507901
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	3.0	ug.mL-1	10.1021/jm00066a013
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	4.7	ug.mL-1	10.1021/jm00045a025
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	5.0	ug.mL-1	10.1021/jm00066a013
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	6.25	ug.mL-1	10.1016/S0960-894X(97)00365-X
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	10.0	ug.mL-1	10.1021/jm00402a017
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	13.0	ug.mL-1	10.1021/jm991171l
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	13.7	ug.mL-1	10.1021/jm00045a025
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	25.0	ug.mL-1	10.1021/jm00402a017
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	25.0	ug.mL-1	10.1021/jm9507901
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	28.0	ug.mL-1	10.1021/jm991171l
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	40.0	ug.mL-1	10.1021/jm9507901
Human alphaherpesvirus 3	Human alphaherpesvirus 3	MIC	220.0	ug.mL-1	10.1021/jm00045a025
Human betaherpesvirus 5	Human betaherpesvirus 5	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	4.8	ug.mL-1	10.1021/jm800050t
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	7.7	ug.mL-1	10.1021/jm800050t
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	7.9	ug.mL-1	10.1021/jm800050t
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	12.0	ug.mL-1	10.1021/jm800050t
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	22.0	ug.mL-1	10.1021/jm800050t
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	91.0	ug.mL-1	10.1021/jm800050t
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	130.0	ug.mL-1	10.1021/jm800050t
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	173.0	ug.mL-1	10.1021/jm800050t
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	510.0	nM	10.1016/j.ejmech.2015.06.024
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	1000.0	nM	10.1021/jm8014662
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	1240.0	nM	10.1016/j.ejmech.2015.06.024
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	2080.0	nM	10.1021/acs.jmedchem.2c00667
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	2270.0	nM	10.1021/acs.jmedchem.2c00667
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	3690.0	nM	10.1021/jm901828c
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	4300.0	nM	10.1021/jm8014662
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	7500.0	nM	10.1021/jm8014662
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	7600.0	nM	10.1021/jm8014662
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	15000.0	nM	10.1021/jm8014662
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	18900.0	nM	10.1021/acs.jmedchem.5b00804
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	45000.0	nM	10.1016/j.ejmech.2009.03.005
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	60400.0	nM	10.1021/jm901828c
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	125000.0	nM	10.1021/jm8014662
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	176000.0	nM	10.1021/jm8014662
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	178000.0	nM	10.1016/j.ejmech.2009.03.005
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	200000.0	nM	10.1021/jm8014662
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	nM	10.1016/s0960-894x(01)00735-1
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	ug.mL-1	10.1016/s0960-894x(98)00122-x
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.bmc.2007.03.061
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.bmc.2008.09.027
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.bmc.2011.04.016
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.bmc.2011.06.045
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.bmc.2017.06.046
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.bmc.2019.02.005
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.ejmech.2011.02.014
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.ejmech.2012.07.027
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.ejmech.2017.12.018
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.ejmech.2018.01.086
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.ejmech.2018.03.008
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.ejmech.2018.07.062
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.ejmech.2022.114618
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1016/j.ejmech.2022.114857
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1021/acs.jmedchem.2c00667
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1021/acs.jmedchem.7b00416
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1021/acs.jmedchem.7b01009
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1021/acsmedchemlett.8b00079
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1021/jm050867d
Human betaherpesvirus 5	Human betaherpesvirus 5	EC50	nan	None	10.1021/jm070210n
Human betaherpesvirus 5	Human betaherpesvirus 5	EC90	nan	None	10.1016/j.ejmech.2011.02.014
Human betaherpesvirus 5	Human betaherpesvirus 5	EC90	nan	None	10.1021/acs.jmedchem.2c00667
Human betaherpesvirus 5	Human betaherpesvirus 5	ED50	6.9	ug ml-1	10.1021/jm9701536
Human betaherpesvirus 5	Human betaherpesvirus 5	ED50	20.0	ug ml-1	10.1021/jm00145a014
Human betaherpesvirus 5	Human betaherpesvirus 5	ED50	20.0	uM	10.1016/S0960-894X(00)80318-2
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	13.0	ug.mL-1	10.1021/jm960314q
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	20000.0	nM	10.1016/j.bmcl.2007.03.102
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	20000.0	nM	10.1016/j.bmcl.2007.05.010
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	20000.0	nM	10.1016/j.bmcl.2008.06.060
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	20000.0	nM	10.1016/j.bmcl.2010.01.094
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	20000.0	nM	10.1016/S0960-894X(00)80317-0
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	63000.0	nM	10.1021/jm00081a014
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	63000.0	nM	10.1021/jm00119a006
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	63000.0	nM	10.1021/jm00122a019
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	63000.0	nM	10.1021/jm00127a003
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	63000.0	nM	10.1021/jm00169a027
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	63000.0	nM	10.1021/jm00169a028
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	63000.0	nM	10.1021/jm00174a011
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	85000.0	nM	10.1021/jm950029r
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	86000.0	nM	10.1021/jm00044a015
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	90000.0	nM	10.1021/jm00169a028
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	100000.0	nM	10.1021/jm00044a015
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	100000.0	nM	10.1021/jm950835y
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	nan	ug.mL-1	10.1016/s0960-894x(02)00535-8
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	nan	None	10.1016/j.bmc.2008.10.081
Human betaherpesvirus 5	Human betaherpesvirus 5	IC50	nan	None	10.1021/jm2001426
Human betaherpesvirus 5	Human betaherpesvirus 5	IC90	85000.0	nM	10.1021/jm00044a015
Human betaherpesvirus 5	Human betaherpesvirus 5	IC90	90000.0	nM	10.1021/jm00081a014
Human betaherpesvirus 5	Human betaherpesvirus 5	IC90	90000.0	nM	10.1021/jm00174a011
Human betaherpesvirus 5	Human betaherpesvirus 5	ID50	38.4	ug ml-1	10.1021/jm00166a019
Human betaherpesvirus 5	Human betaherpesvirus 5	ID50	40.0	uM	10.1021/jm00061a013
Human betaherpesvirus 5	Human betaherpesvirus 5	ID50	100.0	uM	10.1021/jm00147a020
Human betaherpesvirus 5	Human betaherpesvirus 5	Inhibition	nan	%	10.1016/j.bmc.2013.07.031
Human betaherpesvirus 5	Human betaherpesvirus 5	Inhibition	nan	%	10.1021/jm00171a022
Human betaherpesvirus 5	Human betaherpesvirus 5	MIC	13.2	ug.mL-1	10.1021/jm00045a025
Human gammaherpesvirus 4	Human gammaherpesvirus 4	EC50	330.0	nM	10.1021/jm0607404
Human gammaherpesvirus 4	Human gammaherpesvirus 4	EC50	1100.0	nM	10.1021/jm040093l
Human gammaherpesvirus 4	Human gammaherpesvirus 4	EC50	1100.0	nM	10.1021/jm040149b
Human gammaherpesvirus 4	Human gammaherpesvirus 4	EC50	1700.0	nM	10.1016/j.bmc.2007.11.082
Human gammaherpesvirus 4	Human gammaherpesvirus 4	EC50	3300.0	nM	10.1021/jm900126v
Human gammaherpesvirus 4	Human gammaherpesvirus 4	EC50	3960.0	nM	10.1016/s0960-894x(01)00735-1
Human gammaherpesvirus 4	Human gammaherpesvirus 4	EC50	5300.0	nM	10.1021/jm040093l
Human gammaherpesvirus 4	Human gammaherpesvirus 4	EC50	19700.0	nM	10.1021/jm990543n
Human gammaherpesvirus 4	Human gammaherpesvirus 4	EC50	nan	nM	10.1021/jm034265a
Human gammaherpesvirus 4	Human gammaherpesvirus 4	IC50	6900.0	nM	10.1016/j.bmcl.2007.03.102
Human gammaherpesvirus 4	Human gammaherpesvirus 4	IC50	6900.0	nM	10.1016/j.bmcl.2008.06.060
Human gammaherpesvirus 8	Human gammaherpesvirus 8	IC50	100000.0	nM	10.1021/jm070032y
Human herpesvirus 1	Thymidine kinase	IC50	122000.0	nM	10.1128/aac.01284-06
Human herpesvirus 2	Thymidine kinase	IC50	200000.0	nM	10.1128/aac.01284-06
Human herpesvirus 2 strain G	Human herpesvirus 2 strain G	EC50	1.8	ug.mL-1	10.1016/j.bmcl.2012.07.098
Human immunodeficiency virus	Human immunodeficiency virus	EC50	nan	nM	10.1021/jm034265a
Human immunodeficiency virus 1	Human immunodeficiency virus 1	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Human immunodeficiency virus 1	Human immunodeficiency virus 1	CC50	nan	nM	10.1016/s0960-894x(99)00010-4
Human immunodeficiency virus 1	Human immunodeficiency virus 1	EC50	50000.0	nM	10.1021/jm0504306
Human immunodeficiency virus 1	Human immunodeficiency virus 1	EC50	250000.0	nM	10.1016/j.ejmech.2013.09.047
Human immunodeficiency virus 1	Human immunodeficiency virus 1	EC50	250000.0	nM	10.1021/jm9007856
Human immunodeficiency virus 1	Human immunodeficiency virus 1	EC50	nan	nM	10.1016/s0960-894x(00)00418-2
Human immunodeficiency virus 1	Human immunodeficiency virus 1	EC50	nan	nM	10.1016/s0960-894x(99)00010-4
Human immunodeficiency virus 1	Human immunodeficiency virus 1	EC50	nan	ug.mL-1	10.1016/s0960-894x(98)00122-x
Human immunodeficiency virus 1	Human immunodeficiency virus 1	EC50	nan	None	10.1016/j.bmc.2015.09.035
Human immunodeficiency virus 1	Human immunodeficiency virus 1	EC50	nan	None	10.1021/np034052o
Human immunodeficiency virus 1	Human immunodeficiency virus 1	GI	nan	None	10.1016/j.bmc.2012.08.008
Human immunodeficiency virus 1	Human immunodeficiency virus 1	Inhibition	nan	%	10.1021/jm00171a022
Human immunodeficiency virus 2	Human immunodeficiency virus 2	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Human immunodeficiency virus 2	Human immunodeficiency virus 2	EC50	50000.0	nM	10.1021/jm0504306
Human immunodeficiency virus 2	Human immunodeficiency virus 2	EC50	250000.0	nM	10.1021/jm9007856
Human orthopneumovirus	Human orthopneumovirus	EC50	100000.0	nM	10.1016/j.bmc.2015.09.035
Human respirovirus 3	Human respirovirus 3	Activity	nan	None	10.1007/s00044-010-9338-x
Human respirovirus 3	Human respirovirus 3	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Human respirovirus 3	Human respirovirus 3	MIC50	nan	None	10.1021/jm050772b
Human respirovirus 3	Human respirovirus 3	TCID50	0.012	ug ml-1	10.1016/j.ejmech.2010.05.069
Influenza A virus	Influenza A virus	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Influenza A virus	Influenza A virus	IC50	15.7	ug.mL-1	10.1021/np050498o
Influenza A virus	Influenza A virus	IC50	nan	None	10.1021/np0501886
Influenza B virus	Influenza B virus	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Klebsiella pneumoniae	Klebsiella pneumoniae	Inhibition	6.29	%	10.6019/CHEMBL4513141
Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	20000.0	nM	10.6019/CHEMBL4513161
Macacine alphaherpesvirus 1	Macacine alphaherpesvirus 1	Activity	33.0	%	10.1128/aac.01435-08
Macacine alphaherpesvirus 1	Macacine alphaherpesvirus 1	EC50	19300.0	nM	10.1128/aac.01435-08
Macacine alphaherpesvirus 1	Macacine alphaherpesvirus 1	EC50	47500.0	nM	10.1128/aac.01284-06
Macacine alphaherpesvirus 1	Macacine alphaherpesvirus 1	EC50	112000.0	nM	10.1128/aac.01284-06
Macacine alphaherpesvirus 1	Macacine alphaherpesvirus 1	EC50	118000.0	nM	10.1128/aac.01284-06
Macacine herpesvirus 1	Thymidine kinase	Activity	nan	None	10.1128/aac.01284-06
Macacine herpesvirus 1	Thymidine kinase	IC50	1000000.0	nM	10.1128/aac.01284-06
Mammalian orthoreovirus 1	Mammalian orthoreovirus 1	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Mammalian orthoreovirus 1	Mammalian orthoreovirus 1	EC50	100000.0	nM	10.1016/j.bmc.2009.05.020
Mammalian orthoreovirus 1	Mammalian orthoreovirus 1	MIC50	nan	None	10.1021/jm050772b
Mesocricetus auratus	BHK-21	CC100	nan	None	10.1021/acs.jnatprod.2c00464
Mesocricetus auratus	BHK-21	EC50	2000.0	nM	10.1021/jm960324r
Mus musculus	FM3A	Concentration	400.0	ug ml-1	10.1021/jm00171a009
Mus musculus	FM3A	ID50	0.0009	ug ml-1	10.1021/jm00171a009
Mus musculus	FM3A	ID50	0.62	ug ml-1	10.1021/jm00171a009
Mus musculus	FM3A	ID50	17.0	ug ml-1	10.1021/jm00171a009
Mus musculus	FM3A	MIC	66.0	ug.mL-1	10.1021/jm00402a017
Mus musculus	Jejunum	Peff	7.4	ucm/s	10.1124/dmd.112.049239
Mus musculus	L1210	ID50	13.0	ug ml-1	10.1021/jm00377a018
Mus musculus	L1210	ID50	41.0	ug ml-1	10.1021/jm00171a009
Mus musculus	L1210	ID50	50.0	ug ml-1	10.1021/jm00377a018
Mus musculus	L1210	ID50	367.0	ug ml-1	10.1021/jm00377a018
Mus musculus	L1210	MIC	55.0	ug.mL-1	10.1021/jm00402a017
Mus musculus	Monoamine oxidase A	Activity	nan	None	10.1021/jm800656v
Mus musculus	Monoamine oxidase B	Activity	nan	None	10.1021/jm800656v
Mus musculus	Mus musculus	Activity	0.0	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	1.0	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	1.2	%	10.1016/j.bmcl.2012.12.097
Mus musculus	Mus musculus	Activity	2.0	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	3.0	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	6.0	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	7.0	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	10.0	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	11.0	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	13.0	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	14.2	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	15.0	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	15.1	%	10.1016/j.bmcl.2012.12.097
Mus musculus	Mus musculus	Activity	17.2	None	10.1021/jm00171a009
Mus musculus	Mus musculus	Activity	17.2	None	10.1021/jm049059x
Mus musculus	Mus musculus	Activity	18.7	%	10.1016/j.bmcl.2012.12.097
Mus musculus	Mus musculus	Activity	31.2	%	10.1016/j.bmcl.2012.12.097
Mus musculus	Mus musculus	Activity	40.8	None	10.1021/jm00171a009
Mus musculus	Mus musculus	Activity	nan	None	10.1016/j.bmcl.2012.12.097
Mus musculus	Mus musculus	AUC	1129.88	ng.hr.mL-1	10.1124/dmd.112.049239
Mus musculus	Mus musculus	AUC	2781.34	ng.hr.mL-1	10.1124/dmd.112.049239
Mus musculus	Mus musculus	Cmax	2000.0	nM	10.1124/dmd.112.049239
Mus musculus	Mus musculus	Cmax	9300.0	nM	10.1124/dmd.112.049239
Mus musculus	Mus musculus	CMP	10.0	None	10.1021/jm00117a026
Mus musculus	Mus musculus	CMP	15.0	None	10.1021/jm00117a026
Mus musculus	Mus musculus	Efficacy	0.0	mg kg-1	10.1021/jm00152a007
Mus musculus	Mus musculus	Efficacy	nan	None	10.1021/jm00152a007
Mus musculus	Mus musculus	Mean day of death	7.8	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Mean day of death	8.3	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Mean day of death	9.0	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Mean day of death	9.3	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Mean day of death	10.0	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Mean day of death	11.6	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Mean day of death	11.7	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Mean day of death	11.8	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Mean day of death	13.0	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Mean day of death	13.5	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Mean day of death	14.0	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Mean survival time	30.4	day	10.1021/jm00171a009
Mus musculus	Mus musculus	Mean survival time	46.2	day	10.1021/jm00171a009
Mus musculus	Mus musculus	MED	12.0	mg kg-1	10.1021/jm00014a006
Mus musculus	Mus musculus	MST	18.4	day	10.1021/jm00111a052
Mus musculus	Mus musculus	MST	18.6	day	10.1021/jm00117a026
Mus musculus	Mus musculus	MST	18.9	day	10.1021/jm00117a026
Mus musculus	Mus musculus	MST	20.0	day	10.1021/jm00111a052
Mus musculus	Mus musculus	MTD	200.0	mg kg-1	10.1021/jm00014a006
Mus musculus	Mus musculus	No. of dead mice	0.0	None	10.1021/jm00152a007
Mus musculus	Mus musculus	No. of dead mice	1.0	None	10.1021/jm00152a007
Mus musculus	Mus musculus	No. of dead mice	7.0	None	10.1021/jm00152a007
Mus musculus	Mus musculus	No. of mice	5.0	None	10.1021/jm00389a005
Mus musculus	Mus musculus	No. of mice	10.0	None	10.1021/jm00389a005
Mus musculus	Mus musculus	PD50	200.0	mg kg-1 day-1	10.1021/jm00061a013
Mus musculus	Mus musculus	Survival	2.0	%	10.1021/jm00127a010
Mus musculus	Mus musculus	Survival	50.0	%	10.1021/jm00127a010
Mus musculus	Mus musculus	Survival	70.0	%	10.1021/jm00111a052
Mus musculus	Mus musculus	Survival	70.0	%	10.1021/jm00127a010
Mus musculus	Mus musculus	Survival	75.0	%	10.1021/jm00127a010
Mus musculus	Mus musculus	Survival	78.0	%	10.1021/jm00127a010
Mus musculus	Mus musculus	Survival	86.0	%	10.1021/jm00111a052
Mus musculus	Mus musculus	Survival rate	5.0	None	10.1021/jm00389a005
Mus musculus	Mus musculus	Survival rate	10.0	None	10.1021/jm00389a005
Mus musculus	Mus musculus	Survivors	0.0	%	10.1021/jm00149a024
Mus musculus	Mus musculus	Survivors	0.0	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Survivors	1.0	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Survivors	2.0	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Survivors	3.0	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Survivors	4.0	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Survivors	5.0	None	10.1021/jm00061a013
Mus musculus	Mus musculus	Survivors	9.0	%	10.1021/jm00149a024
Mus musculus	Mus musculus	Survivors	54.0	%	10.1021/jm00149a024
Mus musculus	Mus musculus	Survivors	55.0	%	10.1021/jm00149a024
Mus musculus	Mus musculus	Survivors	75.0	%	10.1021/jm00149a024
Mus musculus	Mus musculus	Survivors	83.0	%	10.1021/jm00149a024
Mus musculus	Mus musculus	Survivors	91.0	%	10.1021/jm00149a024
Mus musculus	Mus musculus	Survivors	92.0	%	10.1021/jm00149a024
Mus musculus	Mus musculus	Survivors	100.0	%	10.1021/jm00149a024
Mus musculus	Mus musculus	Survivors	nan	None	10.1021/jm00149a024
Mus musculus	Mus musculus	Tmax	0.4167	hr	10.1124/dmd.112.049239
Mus musculus	Mus musculus	Tmax	1.167	hr	10.1124/dmd.112.049239
Mus musculus	Nitric oxide synthase, inducible	IC50	nan	None	None
Mus musculus	Nitric oxide synthase, inducible	Ki	nan	None	None
Mus musculus	Plasma	Drug metabolism	nan	None	10.1124/dmd.112.049239
Mus musculus	Solute carrier family 15 member 1	Peff	4.0	ucm/s	10.1124/dmd.112.049239
Mycobacterium tuberculosis	Purine nucleoside phosphorylase	Kd	12589.25	nM	10.1016/j.bmc.2010.05.009
Oryctolagus cuniculus	Angiotensin-converting enzyme	IC50	nan	None	None
Oryctolagus cuniculus	Angiotensin-converting enzyme	Ki	nan	None	None
Oryctolagus cuniculus	Arachidonate 15-lipoxygenase	IC50	nan	None	None
Oryctolagus cuniculus	Arachidonate 15-lipoxygenase	Ki	nan	None	None
Oryctolagus cuniculus	Oryctolagus cuniculus	EC50	51000.0	nM	10.1021/jm034265a
Oryctolagus cuniculus	Oryctolagus cuniculus	MIC	0.04	ug.mL-1	10.1021/jm00358a029
Oryctolagus cuniculus	Oryctolagus cuniculus	MIC	0.06	ug.mL-1	10.1021/jm00358a029
Oryctolagus cuniculus	Oryctolagus cuniculus	MIC	0.08	ug.mL-1	10.1021/jm00358a029
Oryctolagus cuniculus	Oryctolagus cuniculus	MIC	0.09	ug.mL-1	10.1021/jm00358a029
Oryctolagus cuniculus	Oryctolagus cuniculus	MIC	0.1	ug.mL-1	10.1021/jm00358a029
Oryctolagus cuniculus	Oryctolagus cuniculus	MIC	80.0	ug.mL-1	10.1021/jm00358a029
Oryctolagus cuniculus	Oryctolagus cuniculus	MIC	400.0	ug.mL-1	10.1021/jm00358a029
Oryctolagus cuniculus	Oryctolagus cuniculus	MTC	440.0	uM	10.1021/jm00117a026
Poliovirus 1	Poliovirus 1	EC50	100000.0	nM	10.1016/j.bmc.2009.05.020
Poliovirus 1	Poliovirus 1	EC50	100000.0	nM	10.1016/j.bmc.2010.02.037
Poliovirus 1	Poliovirus 1	EC50	100000.0	nM	10.1016/j.bmc.2014.06.043
Poliovirus 1	Poliovirus 1	EC50	100000.0	nM	10.1016/j.bmc.2015.09.035
Poliovirus 1	Poliovirus 1	EC50	nan	None	10.1016/j.ejmech.2016.03.080
Poliovirus 1	Poliovirus 1	Inhibition	nan	%	10.1016/j.bmc.2013.07.031
Pseudomonas aeruginosa	Pseudomonas aeruginosa	Inhibition	9.14	%	10.6019/CHEMBL4513141
Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	20000.0	nM	10.6019/CHEMBL4513161
Punta Toro virus	Punta Toro virus	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Punta Toro virus	Punta Toro virus	MIC50	nan	None	10.1021/jm050772b
Rattus norvegicus	Aldose reductase	IC50	nan	None	None
Rattus norvegicus	Aldose reductase	Ki	nan	None	None
Rattus norvegicus	Alpha-1a adrenergic receptor	IC50	nan	None	None
Rattus norvegicus	Alpha-1a adrenergic receptor	Ki	nan	None	None
Rattus norvegicus	Alpha-1b adrenergic receptor	IC50	nan	None	None
Rattus norvegicus	Alpha-1b adrenergic receptor	Ki	nan	None	None
Rattus norvegicus	Androgen Receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Rattus norvegicus	Androgen Receptor	IC50	nan	None	None
Rattus norvegicus	Androgen Receptor	Ki	nan	None	None
Rattus norvegicus	Bile salt export pump	IC50	1000000.0	nM	10.1124/dmd.111.040758
Rattus norvegicus	Cyclooxygenase-1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Rattus norvegicus	GABA receptor alpha-1 subunit	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Rattus norvegicus	GABA receptor alpha-1 subunit	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Rattus norvegicus	Glutamate (NMDA) receptor subunit zeta 1	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Rattus norvegicus	Glycine receptor	IC50	nan	None	None
Rattus norvegicus	Glycine receptor	Ki	nan	None	None
Rattus norvegicus	Insulin receptor	IC50	nan	None	None
Rattus norvegicus	Insulin receptor	Ki	nan	None	None
Rattus norvegicus	Nitric-oxide synthase, brain	IC50	nan	None	None
Rattus norvegicus	Nitric-oxide synthase, brain	Ki	nan	None	None
Rattus norvegicus	Plasma	Fu	0.85	None	10.1021/jm901371v
Rattus norvegicus	Plasma	logFu	0.85	None	10.1016/j.ejmech.2009.06.004
Rattus norvegicus	Rattus norvegicus	ALB	40700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	41000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	41300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	41700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	43000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	300.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	310.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	320.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	321.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	334.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	356.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	46.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	47.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	49.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	50.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	50.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	54.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	74.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	78.17	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	79.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	83.5	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	88.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	89.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BASO	0.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BASOLE	0.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	1.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	1.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	1.8	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	2.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	126.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	140.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	141.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	156.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	160.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	173.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	98.5	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	100.0	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	100.33	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	100.5	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	101.0	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	576.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	673.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	713.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	743.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	765.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	248.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	253.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	328.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	331.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	458.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	489.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	25670000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	28330000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	29330000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	29670000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	31000000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	31330000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	2.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	2.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	3.4	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	3.5	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	4.4	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	0.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	23.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	28.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	32.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	37.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOSLE	0.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOSLE	0.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	F	20.0	%	10.1016/j.ejmech.2016.09.080
Rattus norvegicus	Rattus norvegicus	GLUC	1440.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1496.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1510.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1540.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1556.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1830.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	32.97	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	33.55	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	35.13	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	35.43	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	36.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	36.08	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	128000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	131000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	139000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	139300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	139700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	140700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	107.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	119.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	123.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	133.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	135.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	177.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	9.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	9.83	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	10.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	11.17	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	11.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	12.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	6827.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	6898.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	8681.17	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	9269.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	12359.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	14421.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	92.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	92.5	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	92.67	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	93.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	94.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	95.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	23.83	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	23.92	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	24.1	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	24.17	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	24.37	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	24.47	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	387000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	388700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	389800.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	390700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	394000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	396000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	60.17	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	61.1	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	61.22	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	62.47	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	62.67	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	62.78	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	23.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	45.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	79.83	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	115.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	118.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	122.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	0.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	0.67	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	1.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	1.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	4.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	4.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	6.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	6.17	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	6.67	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	7.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	383.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	428.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	459.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	559.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	689.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	847.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	99.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	108.8	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	113.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	119.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	126.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	128.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	783000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	980670.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1001170.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1125670.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1133330.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1202170.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.5	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.65	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.7	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.85	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	6.3	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	6.75	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	57700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	58300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	58700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	59800.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	60500.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	61700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5270000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5490000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5750000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5770000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5800000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5830000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBCNUC	0.0	/100WBC	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBCNUC	0.17	/100WBC	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBCNUC	0.33	/100WBC	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	142.0	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	142.43	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	144.1	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	145.17	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	145.23	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	145.7	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	Tissue Severity Score	nan	None	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	6.8	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	8.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	9.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	9.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	14.2	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	22.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	7330.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	7400.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	9450.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	9800.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	13370.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	15100.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Serotonin 1a (5-HT1a) receptor	IC50	nan	None	None
Rattus norvegicus	Serotonin 1a (5-HT1a) receptor	Ki	nan	None	None
Rattus norvegicus	Serotonin 1b (5-HT1b) receptor	IC50	nan	None	None
Rattus norvegicus	Serotonin 1b (5-HT1b) receptor	Ki	nan	None	None
Rattus norvegicus	Solute carrier family 22 member 6	Activity	nan	None	None
Rattus norvegicus	Solute carrier family 22 member 6	Km	242000.0	nM	None
Rattus norvegicus	Solute carrier family 22 member 8	Activity	7.66	%	10.1046/j.1471-4159.2002.01108.x
Rattus norvegicus	Thioredoxin reductase 1, cytoplasmic	Potency	2993.5	nM	None
Rattus norvegicus	Voltage-gated L-type calcium channel alpha-1C subunit	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Rattus norvegicus	Voltage-gated N-type calcium channel alpha-1B subunit	AC50	10000.0	nM	10.1038/s41467-023-40064-9
Reovirus sp.	Reovirus sp.	EC50	100000.0	nM	10.1016/j.bmc.2014.06.043
Respiratory syncytial virus	Respiratory syncytial virus	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Respiratory syncytial virus	Respiratory syncytial virus	EC50	100000.0	nM	10.1016/j.bmc.2009.05.020
Respiratory syncytial virus	Respiratory syncytial virus	EC50	100000.0	nM	10.1016/j.bmc.2010.02.037
Respiratory syncytial virus	Respiratory syncytial virus	EC50	100000.0	nM	10.1016/j.bmc.2014.06.043
Respiratory syncytial virus	Respiratory syncytial virus	EC50	nan	None	10.1016/j.ejmech.2016.03.080
Respiratory syncytial virus	Respiratory syncytial virus	IC50	nan	None	10.1021/np050498o
Respiratory syncytial virus	Respiratory syncytial virus	MIC50	nan	None	10.1021/jm050772b
Severe acute respiratory syndrome coronavirus 2	Replicase polyprotein 1ab	Inhibition	6.729	%	10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Hit score	0.1075	None	10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	IC50	19952.62	nM	10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	IC50	20000.0	nM	10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition	0.04	%	10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition	8.75	%	10.21203/rs.3.rs-23951/v1
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition index	0.1444	None	10.1101/2020.04.03.023846
Sindbis virus	Sindbis virus	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Sindbis virus	Sindbis virus	MIC50	nan	None	10.1021/jm050772b
Staphylococcus aureus	Staphylococcus aureus	Inhibition	-22.02	%	10.6019/CHEMBL4513141
Staphylococcus aureus	Staphylococcus aureus	MIC	20000.0	nM	10.6019/CHEMBL4513161
Suid alphaherpesvirus 1	Suid alphaherpesvirus 1	MIC	7.0	ug.mL-1	10.1021/jm00402a017
Vaccinia virus	Vaccinia virus	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Vaccinia virus	Vaccinia virus	EC50	400.0	ug.mL-1	10.1021/jm025569k
Vaccinia virus	Vaccinia virus	EC50	400.0	ug.mL-1	10.1021/jm0701472
Vaccinia virus	Vaccinia virus	EC50	1500.0	nM	10.1016/j.ejmech.2016.03.080
Vaccinia virus	Vaccinia virus	EC50	100000.0	nM	10.1016/j.bmc.2010.02.037
Vaccinia virus	Vaccinia virus	EC50	100000.0	nM	10.1016/j.bmc.2014.06.043
Vaccinia virus	Vaccinia virus	EC50	100000.0	nM	10.1016/j.bmc.2015.09.035
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1007/s00044-012-0184-x
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.bmc.2011.04.016
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.bmc.2011.05.037
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.bmc.2011.06.045
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.bmc.2015.04.079
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.bmc.2017.06.046
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.bmc.2018.05.034
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.bmcl.2012.09.079
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.bmcl.2018.09.019
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.ejmech.2010.12.017
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.ejmech.2012.03.007
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.ejmech.2012.08.042
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.ejmech.2013.02.039
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.ejmech.2013.05.046
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.ejmech.2013.06.036
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.ejmech.2015.06.024
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.ejmech.2018.01.086
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.ejmech.2018.07.062
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.ejmech.2019.111739
Vaccinia virus	Vaccinia virus	EC50	250000.0	nM	10.1016/j.ejmech.2022.114618
Vaccinia virus	Vaccinia virus	EC50	300000.0	nM	10.1021/jm060030y
Vaccinia virus	Vaccinia virus	EC50	1000000.0	nM	10.1016/j.ejmech.2012.07.027
Vaccinia virus	Vaccinia virus	EC50	nan	None	10.1016/j.ejmech.2011.02.014
Vaccinia virus	Vaccinia virus	EC90	nan	None	10.1016/j.ejmech.2011.02.014
Vaccinia virus	Vaccinia virus	ED50	110.0	ug ml-1	10.1021/jm00172a026
Vaccinia virus	Vaccinia virus	IC50	384.0	nM	10.1016/j.bmc.2008.11.075
Vaccinia virus	Vaccinia virus	IC50	nan	None	10.1021/jm2001426
Vaccinia virus	Vaccinia virus	ID50	50.0	ug ml-1	10.1021/jm00377a018
Vaccinia virus	Vaccinia virus	ID50	440.0	uM	10.1021/jm00061a013
Vaccinia virus	Vaccinia virus	MIC	80.0	ug.mL-1	10.1021/jm010922s
Vaccinia virus	Vaccinia virus	MIC	150.0	ug.mL-1	10.1021/jm00402a017
Vaccinia virus	Vaccinia virus	MIC	180.0	ug.mL-1	10.1021/jm00045a025
Vaccinia virus	Vaccinia virus	MIC	400.0	ug.mL-1	10.1016/j.ejmech.2007.04.010
Vaccinia virus	Vaccinia virus	MIC	400.0	ug.mL-1	10.1021/jm00035a010
Vaccinia virus	Vaccinia virus	MIC	400.0	ug.mL-1	10.1021/jm00066a013
Vaccinia virus	Vaccinia virus	MIC	500.0	ug.mL-1	10.1007/s00044-012-0127-6
Vaccinia virus	Vaccinia virus	MIC	250000.0	nM	10.1021/jm070324z
Vaccinia virus	Vaccinia virus	MIC	300000.0	nM	10.1016/j.bmc.2006.10.046
Vaccinia virus	Vaccinia virus	MIC	500000.0	nM	10.1021/np060435l
Vaccinia virus	Vaccinia virus	MIC50	250.0	ug.mL-1	10.1016/j.ejmech.2009.02.030
Vaccinia virus	Vaccinia virus	MIC50	400.0	ug.mL-1	10.1021/jm050772b
Vesicular stomatitis virus	Vesicular stomatitis virus	Activity	nan	None	10.1016/j.ejmech.2011.11.021
Vesicular stomatitis virus	Vesicular stomatitis virus	Activity	nan	None	10.1016/j.ejmech.2021.113738
Vesicular stomatitis virus	Vesicular stomatitis virus	EC50	400.0	ug.mL-1	10.1021/jm025569k
Vesicular stomatitis virus	Vesicular stomatitis virus	EC50	100000.0	nM	10.1016/j.bmc.2014.06.043
Vesicular stomatitis virus	Vesicular stomatitis virus	EC50	100000.0	nM	10.1016/j.bmc.2015.09.035
Vesicular stomatitis virus	Vesicular stomatitis virus	EC50	250000.0	nM	10.1007/s00044-012-0184-x
Vesicular stomatitis virus	Vesicular stomatitis virus	EC50	250000.0	nM	10.1016/j.bmcl.2012.09.079
Vesicular stomatitis virus	Vesicular stomatitis virus	EC50	250000.0	nM	10.1016/j.ejmech.2012.03.007
Vesicular stomatitis virus	Vesicular stomatitis virus	EC50	250000.0	nM	10.1016/j.ejmech.2013.05.046
Vesicular stomatitis virus	Vesicular stomatitis virus	EC50	250000.0	nM	10.1016/j.ejmech.2013.06.036
Vesicular stomatitis virus	Vesicular stomatitis virus	EC50	250000.0	nM	10.1016/j.ejmech.2015.06.024
Vesicular stomatitis virus	Vesicular stomatitis virus	EC50	500000.0	nM	10.1021/jm060030y
Vesicular stomatitis virus	Vesicular stomatitis virus	EC50	nan	None	10.1016/j.ejmech.2016.03.080
Vesicular stomatitis virus	Vesicular stomatitis virus	ED50	40.0	ug ml-1	10.1021/jm00172a026
Vesicular stomatitis virus	Vesicular stomatitis virus	ED50	1411.0	umol/L	10.1016/j.bmcl.2014.11.065
Vesicular stomatitis virus	Vesicular stomatitis virus	ID50	400.0	ug ml-1	10.1021/jm00377a018
Vesicular stomatitis virus	Vesicular stomatitis virus	MIC	80.0	ug.mL-1	10.1021/jm010922s
Vesicular stomatitis virus	Vesicular stomatitis virus	MIC	400.0	ug.mL-1	10.1016/j.ejmech.2007.04.010
Vesicular stomatitis virus	Vesicular stomatitis virus	MIC	400.0	ug.mL-1	10.1021/jm00035a010
Vesicular stomatitis virus	Vesicular stomatitis virus	MIC	400.0	ug.mL-1	10.1021/jm00066a013
Vesicular stomatitis virus	Vesicular stomatitis virus	MIC	500.0	ug.mL-1	10.1007/s00044-012-0127-6
Vesicular stomatitis virus	Vesicular stomatitis virus	MIC	500000.0	nM	10.1016/j.bmc.2006.10.046
Vesicular stomatitis virus	Vesicular stomatitis virus	MIC	500000.0	nM	10.1021/np060435l
Vesicular stomatitis virus	Vesicular stomatitis virus	MIC50	250.0	ug.mL-1	10.1016/j.ejmech.2009.02.030
Vesicular stomatitis virus	Vesicular stomatitis virus	MIC50	400.0	ug.mL-1	10.1021/jm050772b
Vesicular stomatitis virus	Vesicular stomatitis virus	MIC50	nan	None	10.1021/jm050772b
West Nile virus	West Nile virus	EC50	nan	None	10.1016/j.bmc.2015.09.035
Yellow fever virus	Yellow fever virus	EC50	100000.0	nM	10.1016/j.bmc.2009.05.020
Yellow fever virus	Yellow fever virus	EC50	100000.0	nM	10.1016/j.bmc.2010.02.037
Yellow fever virus	Yellow fever virus	EC50	100000.0	nM	10.1016/j.bmc.2014.06.043
Yellow fever virus	Yellow fever virus	EC50	100000.0	nM	10.1016/j.bmc.2015.09.035
Yellow fever virus	Yellow fever virus	EC50	nan	None	10.1016/j.ejmech.2016.03.080
Zika virus	Zika virus	EC	nan	None	10.1021/acs.jnatprod.2c00464
None	ADMET	Activity	nan	None	10.1021/acsmedchemlett.5b00318
None	ADMET	CC50	10000.0	nM	10.1021/jm040093l
None	ADMET	CC50	13000.0	nM	10.1016/j.ejmech.2015.06.027
None	ADMET	CC50	100000.0	nM	10.1016/j.bmc.2009.05.020
None	ADMET	CC50	100000.0	nM	10.1016/j.bmc.2010.02.037
None	ADMET	CC50	100000.0	nM	10.1016/j.bmc.2011.05.037
None	ADMET	CC50	100000.0	nM	10.1016/j.bmc.2014.06.043
None	ADMET	CC50	100000.0	nM	10.1016/j.bmc.2015.09.035
None	ADMET	CC50	100000.0	nM	10.1016/j.bmcl.2015.04.006
None	ADMET	CC50	100000.0	nM	10.1016/j.bmcl.2015.05.039
None	ADMET	CC50	100000.0	nM	10.1016/j.ejmech.2014.07.011
None	ADMET	CC50	100000.0	nM	10.1016/j.ejmech.2016.03.080
None	ADMET	CC50	100000.0	nM	10.1021/acs.jmedchem.5b00804
None	ADMET	CC50	100000.0	nM	10.1021/jm040149b
None	ADMET	CC50	100000.0	nM	10.1021/jm900126v
None	ADMET	CC50	630000.0	nM	10.1016/j.bmcl.2012.12.097
None	ADMET	CC50	1000000.0	nM	10.1016/j.bmcl.2015.05.039
None	ADMET	CC50	1778000.0	nM	10.1016/j.bmc.2010.12.052
None	ADMET	CC50	nan	ug.mL-1	10.1016/S0960-894X(01)80693-4
None	ADMET	CC50	nan	None	10.1016/j.bmc.2011.04.016
None	ADMET	CC50	nan	None	10.1016/j.ejmech.2016.03.080
None	ADMET	CC50	nan	None	10.1021/np050498o
None	ADMET	CL	3.4	mL.min-1.kg-1	10.1002/jps.20373
None	ADMET	CL	4.7	mL.min-1.kg-1	10.1124/dmd.108.020479
None	ADMET	CL	5.8	mL.min-1.kg-1	10.1002/jps.20373
None	ADMET	CL	6.7	mL.min-1.kg-1	10.1002/jps.20373
None	ADMET	CL	8.4	mL.min-1.kg-1	10.1002/jps.20373
None	ADMET	Drugabsorption	2.98	%	10.1016/j.ejmech.2020.112492
None	ADMET	Drug transport	nan	None	10.1124/dmd.111.042036
None	ADMET	EC50	0.077	ug.mL-1	10.1021/jm025569k
None	ADMET	EC50	0.384	ug.mL-1	10.1021/jm025569k
None	ADMET	EC50	48.0	ug.mL-1	10.1021/jm025569k
None	ADMET	EC50	13600.0	nM	10.1021/jm990543n
None	ADMET	F	54.0	%	10.1021/acs.jmedchem.2c00668
None	ADMET	F	63.0	%	10.1021/acs.jmedchem.2c00668
None	ADMET	F	65.0	%	10.1021/acs.jmedchem.2c00668
None	ADMET	F	83.0	%	10.1021/acs.jmedchem.2c00668
None	ADMET	FA	19.0	%	10.1021/jm049711o
None	ADMET	Fu	0.8	ug ml-1	10.1128/aac.00116-07
None	ADMET	IC50	0.02	ug.mL-1	10.1021/jm960314q
None	ADMET	IC50	10.0	ug.mL-1	10.1021/np9703914
None	ADMET	IC50	67.0	ug.mL-1	10.1021/np9703914
None	ADMET	IC50	1700.0	nM	10.1021/jm950029r
None	ADMET	IC50	2600.0	nM	10.1021/jm00122a019
None	ADMET	IC50	57730.0	nM	10.1021/jm061445m
None	ADMET	IC50	100000.0	nM	10.1021/jm00081a014
None	ADMET	IC50	100000.0	nM	10.1021/jm00119a006
None	ADMET	IC50	100000.0	nM	10.1021/jm00122a019
None	ADMET	IC50	100000.0	nM	10.1021/jm00127a003
None	ADMET	IC50	100000.0	nM	10.1021/jm00169a027
None	ADMET	IC50	100000.0	nM	10.1021/jm00169a028
None	ADMET	IC50	100000.0	nM	10.1021/jm00174a011
None	ADMET	IC50	100000.0	nM	10.1021/jm00403a005
None	ADMET	IC50	100000.0	nM	10.1021/jm070032y
None	ADMET	ID50	0.9	uM	10.1021/jm00061a013
None	ADMET	ID50	2.0	uM	10.1021/jm00061a013
None	ADMET	ID50	12.0	ug ml-1	10.1021/jm00377a018
None	ADMET	ID50	13.0	ug ml-1	10.1021/jm00377a018
None	ADMET	ID50	360.0	uM	10.1021/jm00397a022
None	ADMET	Inhibition	100.0	%	10.1021/jm00119a006
None	ADMET	LD50	1250.0	mg.kg-1	10.1021/jm00152a007
None	ADMET	Log Pe	-4.8	cm s-1	10.1021/jm001020e
None	ADMET	MCC	1778000.0	nM	10.1016/j.bmc.2010.12.052
None	ADMET	MIC	0.005	ug.mL-1	10.1021/jm991171l
None	ADMET	MIC	0.01	ug.mL-1	10.1021/jm991171l
None	ADMET	MIC	0.02	ug.mL-1	10.1021/jm00171a009
None	ADMET	MIC	0.02	ug.mL-1	10.1021/jm991171l
None	ADMET	MIC	0.07	ug.mL-1	10.1021/jm00035a010
None	ADMET	MIC	0.07	ug.mL-1	10.1021/jm00171a009
None	ADMET	MIC	0.1	ug.mL-1	10.1021/jm00171a009
None	ADMET	MIC	0.2	ug.mL-1	10.1021/jm00171a009
None	ADMET	MIC	8.0	ug.mL-1	10.1021/jm00402a017
None	ADMET	MIC	10.0	ug.mL-1	10.1021/jm00171a009
None	ADMET	MIC	20.0	ug.mL-1	10.1021/jm00171a009
None	ADMET	MIC	150.0	ug.mL-1	10.1021/jm00171a009
None	ADMET	MIC	400.0	ug.mL-1	10.1021/jm00171a009
None	ADMET	MNCC	1.6	ug ml-1	10.1007/s00044-010-9338-x
None	ADMET	MNCC	nan	None	10.1021/np050498o
None	ADMET	MNTD	1.6	ug ml-1	10.1016/j.ejmech.2010.05.069
None	ADMET	MRT	2.5	hr	10.1124/dmd.108.020479
None	ADMET	Papp	0.38	cm/s * 10E6	10.1021/jm049711o
None	ADMET	Papp	8.2	cm/s * 10E6	10.1021/jm049711o
None	ADMET	Papp	93.0	cm/s * 10E6	10.1021/jm049711o
None	ADMET	permeability	0.01	10^6cm/s	10.1021/jm070836d
None	ADMET	permeability	0.01	10^6cm/s	10.1021/jm701044r
None	ADMET	permeability	0.06	10^-6 cm/s	10.1016/j.ejmech.2020.112492
None	ADMET	permeability	0.08	10^-6 cm/s	10.1016/j.ejmech.2020.112492
None	ADMET	permeability	0.8	10'-6 cm/s	10.1021/jm901421c
None	ADMET	Permeability coefficient	6.21	None	10.1021/jm960163r
None	ADMET	PPB	10.0	%	10.1128/aac.00116-07
None	ADMET	PPB	10.09	%	10.6019/CHEMBL3301361
None	ADMET	PPB	25.75	%	10.6019/CHEMBL3301361
None	ADMET	Ratio	21.9	None	10.1021/acs.jnatprod.1c00400
None	ADMET	Ratio	27.9	None	10.1021/acs.jnatprod.1c00400
None	ADMET	Ratio CC50/EC50	1.5	None	10.1016/j.ejmech.2021.113467
None	ADMET	Ratio CC50/EC50	3.8	None	10.1016/j.bmc.2012.08.008
None	ADMET	Ratio CC50/EC50	36.0	None	10.1021/acs.jmedchem.2c00667
None	ADMET	Ratio CC50/EC50	69.0	None	10.1016/j.ejmech.2022.114443
None	ADMET	Ratio CC50/EC50	1176.0	None	10.1016/j.bmc.2012.08.008
None	ADMET	Ratio CC50/EC50	nan	None	10.1021/acs.jmedchem.2c00667
None	ADMET	Ratio CC50/IC50	80.0	None	10.1016/j.ejmech.2019.02.048
None	ADMET	Ratio CC50/IC50	85.0	None	10.1016/j.ejmech.2019.02.048
None	ADMET	Ratio CC50/IC50	93.0	None	10.1016/j.ejmech.2019.02.048
None	ADMET	Ratio CC50/IC50	nan	None	10.1021/np050498o
None	ADMET	Selectivity Index	7.0	None	10.1016/j.ejmech.2021.113738
None	ADMET	Selectivity Index	14.0	None	10.1016/j.ejmech.2021.113738
None	ADMET	T1/2	1.0	hr	10.1021/acs.jmedchem.2c00668
None	ADMET	T1/2	1.3	hr	10.1021/acs.jmedchem.2c00668
None	ADMET	T1/2	2.5	hr	10.1124/dmd.108.020479
None	ADMET	T1/2	2.7	hr	10.1021/acs.jmedchem.2c00668
None	ADMET	Therapeutic index	3.8	None	10.1021/jm00088a015
None	ADMET	TI	116.27	None	10.1016/j.bmcl.2011.01.098
None	ADMET	TI	160.0	None	10.1021/jm030206l
None	ADMET	TI	172.42	None	10.1016/j.bmcl.2011.01.098
None	ADMET	TI	800.0	None	10.1021/jm030206l
None	ADMET	Vdss	0.61	L.kg-1	10.1002/jps.20373
None	ADMET	Vdss	0.69	L.kg-1	10.1002/jps.20373
None	ADMET	Vdss	0.7	mL/min/kg	10.1002/jps.20373
None	ADMET	Vdss	0.71	L.kg-1	10.1124/dmd.108.020479
None	ADMET	Vdss	1.2	L.kg-1	10.1002/jps.20373
None	ADMET	Virus yield	2.0	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	3.1	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	3.3	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	3.6	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	3.8	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	4.1	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	4.8	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	5.0	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	5.2	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	5.3	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	5.6	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	5.7	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	5.8	log pfu ml-1	10.1021/jm00389a005
None	ADMET	Virus yield	5.9	log pfu ml-1	10.1021/jm00389a005
None	Erythrocyte	HC10	20.0	uM	10.6019/CHEMBL4513161
None	ESM	MIC	0.007	ug.mL-1	10.1021/jm00112a010
None	ESM	MIC	0.01	ug.mL-1	10.1021/jm00112a010
None	ESM	MIC	0.02	ug.mL-1	10.1021/jm00112a010
None	ESM	MIC	0.07	ug.mL-1	10.1021/jm00112a010
None	ESM	MIC	40.0	ug.mL-1	10.1021/jm00112a010
None	ESM	MIC	100.0	ug.mL-1	10.1021/jm00112a010
None	ESM	MIC	200.0	ug.mL-1	10.1021/jm00112a010
None	ESM	MIC	400.0	ug.mL-1	10.1021/jm00035a010
None	ESM	MIC	400.0	ug.mL-1	10.1021/jm00112a010
None	Hepatotoxicity	Alkaline Phosphatase Increase - Activity Score	nan	None	10.2174/1570163043334794
None	Hepatotoxicity	Alkaline Phosphatase Increase - Index Value	0.9	None	10.2174/1570163043334794
None	Hepatotoxicity	Alkaline Phosphatase Increase - Number of Reports	4.0	None	10.2174/1570163043334794
None	Hepatotoxicity	Composite Activity - Active	0.0	None	10.2174/1570163043334794
None	Hepatotoxicity	Composite Activity - Marginal	0.0	None	10.2174/1570163043334794
None	Hepatotoxicity	Composite Activity - Score	nan	None	10.2174/1570163043334794
None	Hepatotoxicity	GGT Increase - Activity Score	nan	None	10.2174/1570163043334794
None	Hepatotoxicity	GGT Increase - Index Value	0.0	None	10.2174/1570163043334794
None	Hepatotoxicity	GGT Increase - Number of Reports	4.0	None	10.2174/1570163043334794
None	Hepatotoxicity	Hepatotoxicity	nan	None	10.1021/tx900326k
None	Hepatotoxicity	HepSE_bilirubinemia	1.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_cholecystitis	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_cholelithiasis	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_cirrhosis	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_Combined Scores	4.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_elevated liver function tests	1.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_hepatic failure	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_hepatic necrosis	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_hepatitis	1.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_hepatomegaly	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_jaundice	1.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_liver disease	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_liver fatty	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_liver function tests abnormal	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	LDH Increase - Activity Score	nan	None	10.2174/1570163043334794
None	Hepatotoxicity	LDH Increase - Index Value	0.1	None	10.2174/1570163043334794
None	Hepatotoxicity	LDH Increase - Number of Reports	4.0	None	10.2174/1570163043334794
None	Hepatotoxicity	LTKB_BD DILI severity score	5.0	None	10.1016/j.drudis.2011.05.007
None	Hepatotoxicity	SGOT Increase - Activity Score	nan	None	10.2174/1570163043334794
None	Hepatotoxicity	SGOT Increase - Index Value	0.9	None	10.2174/1570163043334794
None	Hepatotoxicity	SGOT Increase - Number of Reports	4.0	None	10.2174/1570163043334794
None	Hepatotoxicity	SGPT Increase - Activity Score	nan	None	10.2174/1570163043334794
None	Hepatotoxicity	SGPT Increase - Index Value	0.1	None	10.2174/1570163043334794
None	Hepatotoxicity	SGPT Increase - Number of Reports	4.0	None	10.2174/1570163043334794
None	Molecular identity unknown	EC50	1500.0	nM	10.1016/j.bmcl.2005.05.071
None	Molecular identity unknown	EC50	1600.0	nM	10.1021/jm040149b
None	Molecular identity unknown	EC50	3100.0	nM	10.1016/j.bmcl.2005.05.071
None	Molecular identity unknown	EC50	40000.0	nM	10.1016/j.bmcl.2005.05.071
None	Molecular identity unknown	EC50	53000.0	nM	10.1016/j.bmcl.2005.05.071
None	NON-PROTEIN TARGET	CC50	100000.0	nM	10.1016/j.bmc.2014.06.043
None	NON-PROTEIN TARGET	CC50	191000.0	nM	10.1016/j.ejmech.2016.09.014
None	NON-PROTEIN TARGET	Control	100.0	%	10.1021/jm00145a010
None	NON-PROTEIN TARGET	EC50	1900.0	nM	10.1016/j.ejmech.2016.09.014
None	NON-PROTEIN TARGET	EC50	26000.0	nM	10.1016/j.ejmech.2016.09.014
None	NON-PROTEIN TARGET	EC50	100000.0	nM	10.1016/j.bmcl.2015.05.039
None	NON-PROTEIN TARGET	EC50	1000000.0	nM	10.1016/j.bmcl.2015.05.039
None	NON-PROTEIN TARGET	EC50	nan	None	10.1016/j.bmc.2015.09.035
None	NON-PROTEIN TARGET	EC50	nan	None	10.1016/j.ejmech.2011.02.014
None	NON-PROTEIN TARGET	EC50	nan	None	10.1016/j.ejmech.2016.03.080
None	NON-PROTEIN TARGET	EC50	nan	None	10.1016/j.ejmech.2016.09.014
None	NON-PROTEIN TARGET	EC90	nan	None	10.1016/j.ejmech.2011.02.014
None	NON-PROTEIN TARGET	ED50	3.0	ug ml-1	10.1021/jm00120a010
None	NON-PROTEIN TARGET	Fu	0.85	None	10.1124/dmd.108.020479
None	NON-PROTEIN TARGET	Hepatotoxicity (acute)	1.9	%	10.1016/s0399-8320(04)95062-2
None	NON-PROTEIN TARGET	Hepatotoxicity (animal toxicity known)	nan	None	10.1016/s0399-8320(04)95062-2
None	NON-PROTEIN TARGET	Hepatotoxicity (benign tumour)	0.0	None	10.1016/s0399-8320(04)95062-2
None	NON-PROTEIN TARGET	Hepatotoxicity (granulomatous hepatitis)	0.0	None	10.1016/s0399-8320(04)95062-2
None	NON-PROTEIN TARGET	Hepatotoxicity (mechanism)	nan	None	10.1016/s0399-8320(04)95062-2
None	NON-PROTEIN TARGET	Hepatotoxicity (moderate)	18.0	None	10.1016/s0399-8320(04)95062-2
None	NON-PROTEIN TARGET	Hepatotoxicity (moderate)	50.0	%	10.1016/s0399-8320(04)95062-2
None	NON-PROTEIN TARGET	Hepatotoxicity (time to onset)	nan	None	10.1016/s0399-8320(04)95062-2
None	NON-PROTEIN TARGET	IC50	0.015	ug.mL-1	10.1021/jm960314q
None	NON-PROTEIN TARGET	IC50	0.81	ug.mL-1	10.1021/jm9904194
None	NON-PROTEIN TARGET	IC50	250.0	ug.mL-1	10.1016/s0960-894x(98)00122-x
None	NON-PROTEIN TARGET	IC50	390.0	nM	10.1016/j.bmcl.2009.08.009
None	NON-PROTEIN TARGET	IC50	nan	None	10.1021/jm2001426
None	NON-PROTEIN TARGET	ID50	100.0	ug ml-1	10.1021/jm00167a002
None	NON-PROTEIN TARGET	MCC	400.0	ug.mL-1	10.1021/jm010922s
None	NON-PROTEIN TARGET	MCC	200000.0	nM	10.1016/j.bmcl.2005.05.071
None	NON-PROTEIN TARGET	MCC	200000.0	nM	10.1016/s0960-894x(00)00193-1
None	NON-PROTEIN TARGET	MCC	250000.0	nM	10.1016/j.ejmech.2016.09.014
None	NON-PROTEIN TARGET	MCC	1776000.0	nM	10.1021/jm020827z
None	NON-PROTEIN TARGET	MIC	0.009	ug.mL-1	10.1021/jm00045a025
None	NON-PROTEIN TARGET	MIC	0.01	ug.mL-1	10.1021/jm00045a025
None	NON-PROTEIN TARGET	MIC	0.02	ug.mL-1	10.1021/jm00045a025
None	NON-PROTEIN TARGET	MIC	0.02	ug.mL-1	10.1021/jm991171l
None	NON-PROTEIN TARGET	MIC	0.07	ug.mL-1	10.1021/jm00045a025
None	NON-PROTEIN TARGET	MIC	0.07	ug.mL-1	10.1021/jm991171l
None	NON-PROTEIN TARGET	MIC	0.09	ug.mL-1	10.1021/jm00045a025
None	NON-PROTEIN TARGET	MIC	1.1	ug.mL-1	10.1021/jm991171l
None	NON-PROTEIN TARGET	MIC	9.6	ug.mL-1	10.1021/jm991171l
None	NON-PROTEIN TARGET	MIC	242.0	nM	10.1021/jm020827z
None	NON-PROTEIN TARGET	MIC	341.0	nM	10.1021/jm020827z
None	NON-PROTEIN TARGET	MIC	400.0	ug.mL-1	10.1016/S0960-894X(96)00254-5
None	NON-PROTEIN TARGET	MIC	1000.0	nM	10.1021/jm020827z
None	NON-PROTEIN TARGET	MIC	249000.0	nM	10.1021/jm020827z
None	NON-PROTEIN TARGET	Potency	1.7	nM	None
None	NON-PROTEIN TARGET	Potency	2.4	nM	None
None	NON-PROTEIN TARGET	Potency	2.7	nM	None
None	NON-PROTEIN TARGET	Potency	211.2	nM	None
None	NON-PROTEIN TARGET	Potency	5623.4	nM	None
None	NON-PROTEIN TARGET	Ratio CC50/EC50	10.4	None	10.1016/j.ejmech.2013.12.055
None	NON-PROTEIN TARGET	Ratio CC50/EC50	30.3	None	10.1016/j.ejmech.2013.12.055
None	NON-PROTEIN TARGET	Selectivity index	nan	None	10.1021/jm981051y
None	NON-PROTEIN TARGET	Selectivity Index	2.4	None	10.1016/j.bmcl.2014.11.065
None	No relevant target	Fa	13.36	%	10.1039/C9MD00358D
None	No relevant target	LogD	-2.0	None	10.1021/jm001020e
None	No relevant target	LogD7.4	-1.42	None	10.6019/CHEMBL3301361
None	No relevant target	LogP	-1.59	None	10.1128/aac.00116-07
None	No relevant target	LogP	1.0	None	10.1021/acs.jmedchem.0c00415
None	No relevant target	LogP	1.6	None	10.1021/jm0209275
None	No relevant target	Peff	0.0	10'-6 cm/s	10.1039/C9MD00358D
None	No relevant target	Peff	0.6	10'-6 cm/s	10.1039/C9MD00358D
None	No relevant target	permeability	0.0	ucm/s	10.1016/j.ejmech.2018.01.007
None	No relevant target	permeability	0.1	ucm/s	10.1016/j.ejmech.2018.01.007
None	No relevant target	pKa_A1	9.26	None	10.6019/CHEMBL3301361
None	No relevant target	pKa_B1	2.2	None	10.6019/CHEMBL3301361
None	No relevant target	Solubility	1000.0	ug.mL-1	10.1128/aac.00116-07
None	No relevant target	Solubility	1290.0	ug.mL-1	10.1016/j.ejmech.2013.10.001
None	No relevant target	Solubility	2500.0	ug.mL-1	10.1021/acs.jmedchem.1c00790
None	No relevant target	Solubility	3920.0	ug.mL-1	10.1021/acs.jmedchem.5b00804
None	No relevant target	Stability	5.0	%	10.1124/dmd.112.049239
None	Nucleic Acid	EC50	6750.0	nM	10.1021/jm0209275
None	Nucleic Acid	EC50	nan	ug.mL-1	10.1016/s0960-894x(01)00589-3
None	Unchecked	Ac50	0.631	uM	None
None	Unchecked	Ac50	0.7079	uM	None
None	Unchecked	Ac50	6.31	uM	None
None	Unchecked	Ac50	11.22	uM	None
None	Unchecked	Ac50	14.13	uM	None
None	Unchecked	AC50	631.0	nM	None
None	Unchecked	AC50	707.9	nM	None
None	Unchecked	AC50	6309.6	nM	None
None	Unchecked	AC50	11220.2	nM	None
None	Unchecked	AC50	14130.0	nM	None
None	Unchecked	Animal death	18.9	%	10.1021/jm010216r
None	Unchecked	Animal death	21.0	%	10.1021/jm010216r
None	Unchecked	Antiviral index	300.0	None	10.1021/jm00377a018
None	Unchecked	CC50	1000.0	ug.mL-1	10.1016/j.ejmech.2019.02.048
None	Unchecked	CC50	440000.0	nM	10.1016/j.ejmech.2018.07.062
None	Unchecked	CC50	440000.0	nM	10.1016/j.ejmech.2019.111739
None	Unchecked	EC50	0.384	ug.mL-1	10.1021/jm025569k
None	Unchecked	EC50	990.0	nM	10.1021/acs.jmedchem.6b00659
None	Unchecked	EC50	nan	nM	10.1021/jm034265a
None	Unchecked	EC50	nan	None	10.1021/acsmedchemlett.0c00485
None	Unchecked	EC50	nan	None	10.1039/d1md00086a
None	Unchecked	EC90	nan	None	10.1039/d1md00086a
None	Unchecked	Hepatotoxicity (acute)	1.0	None	10.1016/s0399-8320(04)95062-2
None	Unchecked	Hepatotoxicity (association with vascular disease)	0.0	None	10.1016/s0399-8320(04)95062-2
None	Unchecked	Hepatotoxicity (choleostasis)	0.0	None	10.1016/s0399-8320(04)95062-2
None	Unchecked	Hepatotoxicity (chronic liver disease)	0.0	None	10.1016/s0399-8320(04)95062-2
None	Unchecked	Hepatotoxicity (cirrhosis)	0.0	None	10.1016/s0399-8320(04)95062-2
None	Unchecked	Hepatotoxicity (comment)	nan	None	10.1016/s0399-8320(04)95062-2
None	Unchecked	Hepatotoxicity (cytolytic)	1.0	None	10.1016/s0399-8320(04)95062-2
None	Unchecked	Hepatotoxicity (malignant tumour)	0.0	None	10.1016/s0399-8320(04)95062-2
None	Unchecked	Hepatotoxicity (severe hepatitis)	0.0	None	10.1016/s0399-8320(04)95062-2
None	Unchecked	Hepatotoxicity (steatosis)	0.0	None	10.1016/s0399-8320(04)95062-2
None	Unchecked	Hepatotoxicity (successful reintroduction)	nan	None	10.1016/s0399-8320(04)95062-2
None	Unchecked	IC50	20000.0	nM	10.1016/j.bmcl.2010.03.115
None	Unchecked	IC50	100000.0	nM	10.1021/jm070357e
None	Unchecked	IC50	nan	None	None
None	Unchecked	Inhibition	40.0	%	10.1021/jm00120a010
None	Unchecked	Inhibition	nan	%	10.1016/S0960-894X(97)00325-9
None	Unchecked	Inhibition	nan	%	10.1038/nchembio873
None	Unchecked	Ki	nan	None	None
None	Unchecked	MCC	250000.0	nM	10.1016/j.ejmech.2018.07.062
None	Unchecked	MCC	250000.0	nM	10.1016/j.ejmech.2019.111739
None	Unchecked	MCC	444000.0	nM	10.1016/j.ejmech.2022.114857
None	Unchecked	Papp	0.034	cm/s * 10E6	10.1021/jm049711o
None	Unchecked	Potency	12589.3	nM	None
None	Unchecked	Ratio	0.33	None	10.1021/jm00389a019
None	Unchecked	Ratio CC50/EC50	8.0	None	10.1016/j.ejmech.2018.01.086
None	Unchecked	Ratio CC50/EC50	19.0	None	10.1021/acsmedchemlett.0c00485
None	Unchecked	Ratio CC50/EC50	36.0	None	10.1039/d1md00086a
None	Unchecked	Ratio CC50/EC50	61.9	None	10.1016/j.bmcl.2012.07.098
None	Unchecked	Ratio CC50/EC50	72.2	None	10.1016/j.bmcl.2012.07.098
None	Unchecked	Ratio CC50/EC50	81.3	None	10.1016/j.bmcl.2012.07.098
None	Unchecked	Ratio CC50/EC50	86.0	None	10.1016/j.bmc.2020.115378
None	Unchecked	Ratio CC50/EC50	106.95	None	10.1016/j.bmcl.2012.05.079
None	Unchecked	Ratio CC50/EC50	150.0	None	10.1016/j.ejmech.2018.01.086
None	Unchecked	Ratio CC50/EC50	150.0	None	10.1128/aac.00417-09
None	Unchecked	Ratio CC50/EC50	166.67	None	10.1016/j.bmcl.2012.05.079
None	Unchecked	Ratio CC50/EC50	265.0	None	10.1021/acsmedchemlett.0c00485
None	Unchecked	Ratio CC50/EC50	300.0	None	10.1021/acs.jmedchem.6b00659
None	Unchecked	Ratio CC50/EC50	850.0	None	10.1007/s00044-011-9574-8
None	Unchecked	Ratio CC50/EC50	880.0	None	10.1007/s00044-007-9035-6
None	Unchecked	Ratio CC50/EC50	916.0	None	10.1016/j.bmc.2020.115378
None	Unchecked	Ratio CC50/IC50	619.0	None	10.1016/j.ejmech.2019.01.076
None	Unchecked	Ratio CC50/IC50	869.0	None	10.1016/j.bmc.2011.02.007
None	Unchecked	Ratio CC50/IC50	1333.0	None	10.1021/acs.jnatprod.7b00620
None	Unchecked	Ratio CC50/IC50	1449.0	None	10.1016/j.ejmech.2019.01.076
None	Unchecked	Ratio CC50/IC50	1500.0	None	10.1016/j.bmcl.2018.08.040
None	Unchecked	Ratio CC50/IC50	2000.0	None	10.1021/np050498o
None	Unchecked	Ratio CC50/IC50	nan	None	10.1021/acs.jnatprod.7b00193
None	Unchecked	Ratio CC50/IC50	nan	None	10.1021/np050498o
None	Unchecked	Ratio IC50/EC50	4.3	None	10.1021/np9703914
None	Unchecked	Ratio IC50/EC50	60.0	None	10.1021/np960613i
None	Unchecked	Ratio IC50/EC50	250.0	None	10.1021/np9703914
None	Unchecked	Selectivity	58.0	None	10.1021/jm0209275
None	Unchecked	Selectivity index	10.0	None	10.1021/jm980182w
None	Unchecked	Selectivity index	11.0	None	10.1021/jm980182w
None	Unchecked	Selectivity index	23.0	None	10.1021/jm980182w
None	Unchecked	Selectivity index	32.0	None	10.1021/jm980182w
None	Unchecked	Selectivity index	34.0	None	10.1021/jm980182w
None	Unchecked	Selectivity index	40.0	None	10.1021/jm980182w
None	Unchecked	Selectivity index	50.0	None	10.1021/jm980182w
None	Unchecked	Selectivity index	70.0	None	10.1021/jm980182w
None	Unchecked	Selectivity index	100.0	None	10.1021/jm00027a009
None	Unchecked	Selectivity index	100.0	None	10.1021/jm980182w
None	Unchecked	Selectivity index	117.0	None	10.1021/jm980182w
None	Unchecked	Selectivity index	589.0	None	10.1021/jm980182w
None	Unchecked	Selectivity index	667.0	None	10.1021/jm980182w
None	Unchecked	Selectivity Index	1.0	None	10.1016/j.bmcl.2017.03.100
None	Unchecked	Selectivity Index	16.0	None	10.1016/j.bmcl.2017.03.100
None	Unchecked	Selectivity Index	26.0	None	10.1016/j.bmcl.2017.03.100
None	Unchecked	Selectivity Index	90.9	None	10.1016/j.ejmech.2011.02.014
None	Unchecked	Selectivity Index	128.0	None	10.1016/j.bmcl.2017.03.100
None	Unchecked	Selectivity Index	243.9	None	10.1021/acs.jnatprod.7b01074
None	Unchecked	Selectivity Index	244.0	None	10.1021/acs.jnatprod.6b00585
None	Unchecked	Selectivity Index	256.0	None	10.1016/j.bmcl.2017.03.100
None	Unchecked	Selectivity Index	nan	None	10.1016/j.ejmech.2011.02.014
None	Unchecked	SI	nan	None	10.1021/jm030241s
None	Unchecked	Symptom initiation	15.6	%	10.1021/jm010216r
None	Unchecked	Symptom initiation	19.1	%	10.1021/jm010216r
None	Unchecked	Symptom initiation	21.0	%	10.1021/jm010216r

Metabolism Information

AKRT ID	Reaction	Reaction Link ID
AKRT006303	CC(C)[C@H](N)C(=O)O.Nc1nc2c(ncn2COCCO)c(=O)[nH]1>>CC(C)[C@H](N)C(=O)OCCOCn1cnc2c(=O)[nH]c(N)nc21	MNXR133627
AKRT006338	CC(C)[C@H](N)C(=O)OCCOCn1cnc2c(=O)[nH]c(=N)[nH]c21>>N=c1[nH]c(=O)c2ncn(COCCO)c2[nH]1	enzymemap_52923
AKRT006340	CC(C)[C@H](N)C(=O)OCCOCn1cnc2c(=O)[nH]c(N)nc21>>Nc1nc2c(ncn2COCCO)c(=O)[nH]1	enzymemap_52923
AKRT016375	N=c1[nH]c(=O)c2ncn(COCCO)c2[nH]1>>N=c1[nH]c(=O)c2ncn(COCCOP(=O)(O)O)c2[nH]1	enzymemap_43499
AKRT021261	Nc1nc2c(ncn2COCCO)c(=O)[nH]1>>N=c1nc(O)c2ncn(COCCOP(=O)(O)O)c2[nH]1	MNXR133690
AKRT021262	Nc1nc2c(ncn2COCCO)c(=O)[nH]1>>Nc1nc2c(ncn2COCCOP(=O)(O)O)c(=O)[nH]1	enzymemap_43499