Mannostatin A
AlkaPlorer ID: AK019492
Synonym: None
IUPAC Name: (1R,2R,3R,4S,5R)-4-amino-5-methylsulfanylcyclopentane-1,2,3-triol
Structure
SMILES: CS[C@@H]1[C@@H](N)[C@@H](O)[C@@H](O)[C@H]1O
InChI: InChI=1S/C6H13NO3S/c1-11-6-2(7)3(8)4(9)5(6)10/h2-6,8-10H,7H2,1H3/t2-,3+,4+,5+,6+/m0/s1
InChIKey: BLOFGONIVNXZME-YDMGZANHSA-N
Reference
Structure determination of mannostatins A and B.
PubChem CID: 124189
CAS: 102822-56-0
LOTUS: LTS0169075
SuperNatural Ⅲ: SN0028865-01
{NPAtlas: NPA020732
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptoverticillium verticillium | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 179.241
TPSA？: 86.71000000000001
MolLogP？: -1.8584
Number of H-Donors: 4
Number of H-Acceptors: 5
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Drosophila melanogaster | Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B | IC50 | 150.0 | nM | 10.1016/j.ejmech.2011.01.012 |
| None | Unchecked | IC50 | 240.0 | nM | 10.1016/s0960-894x(99)00224-3 |
| None | Unchecked | IC50 | 350.0 | nM | 10.1016/s0960-894x(00)00162-1 |
| None | Unchecked | IC50 | 3000.0 | nM | 10.1016/j.ejmech.2011.01.012 |