Tecleanthine
AlkaPlorer ID: AK020031
Synonym: None
IUPAC Name: 6,11-dimethoxy-5-methyl-[1,3]dioxolo[4,5-b]acridin-10-one
Structure
SMILES: COC1=C2C(=O)C3=C(C(OC)=CC=C3)N(C)C2=CC2=C1OCO2
InChI: InChI=1S/C17H15NO5/c1-18-10-7-12-16(23-8-22-12)17(21-3)13(10)15(19)9-5-4-6-11(20-2)14(9)18/h4-7H,8H2,1-3H3
InChIKey: QYWWGVQKWKTLMU-UHFFFAOYSA-N
Reference
9-Acridone Insect Antifeedant Alkaloids from Teclea Trichocarpa Bark
PubChem CID: 628642
LOTUS: LTS0101614
SuperNatural Ⅲ: SN0318905
COCONUT: CNP0143067
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Teclea natalensis | Teclea | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 313.3090000000001
TPSA？: 58.92
MolLogP？: 2.4376
Number of H-Donors: 0
Number of H-Acceptors: 6
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 23200.0 | nM | 10.1021/np0106182 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 53000.0 | nM | 10.1021/np0106182 |